{"id":"https://openalex.org/W2000330004","doi":"https://doi.org/10.1210/jcem-20-2-266","title":"PUBERAL MATURATION OF THE NORMAL HUMAN TESTIS. A HISTOLOGIC STUDY","display_name":"PUBERAL MATURATION OF THE NORMAL HUMAN TESTIS. A HISTOLOGIC STUDY","publication_year":1960,"publication_date":"1960-02-01","ids":{"openalex":"https://openalex.org/W2000330004","doi":"https://doi.org/10.1210/jcem-20-2-266","mag":"2000330004","pmid":"https://pubmed.ncbi.nlm.nih.gov/13814792"},"language":"en","primary_location":{"id":"doi:10.1210/jcem-20-2-266","doi":"https://doi.org/10.1210/jcem-20-2-266","is_oa":false,"landing_page_url":"https://doi.org/10.1210/jcem-20-2-266","pdf_url":null,"source":{"id":"https://openalex.org/S205775358","display_name":"The Journal of Clinical Endocrinology & Metabolism","issn_l":"0021-972X","issn":["0021-972X","1945-7197"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Clinical Endocrinology & Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038395116","display_name":"FELIPE A. DE LA BALZE","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"FELIPE A. DE LA BALZE","raw_affiliation_strings":["Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003085409","display_name":"ROBERTO A. MANCINI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"ROBERTO A. MANCINI","raw_affiliation_strings":["Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064491010","display_name":"FRANCISCO ARRILLAGA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"FRANCISCO ARRILLAGA","raw_affiliation_strings":["Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110105804","display_name":"J A Andrada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"JUAN A. ANDRADA","raw_affiliation_strings":["Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084691441","display_name":"Oscar Vilar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"OSCAR VILAR","raw_affiliation_strings":["Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071148904","display_name":"Angel I. Gurtman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"ANGEL I. GURTMAN","raw_affiliation_strings":["Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052183086","display_name":"Oscar W. Davidson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"OSCAR W. DAVIDSON","raw_affiliation_strings":["Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Endocrinolog\u00eda del Instituto National de la Salud y Sra. C\u00e1tedra de Clinica M\u00e9dica de la Facultad de Medicina de Buenos Aires Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I24354313"],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":null,"fwci":2.0094,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.81196581,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"20","issue":"2","first_page":"266","last_page":"285"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9467999935150146,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9467999935150146,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.025499999523162842,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":0.01600000075995922,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/testicular-maturation","display_name":"testicular maturation","score":0.9509999752044678},{"id":"https://openalex.org/keywords/puberty","display_name":"puberty","score":0.9819999933242798},{"id":"https://openalex.org/keywords/testis-histology","display_name":"testicular histology","score":0.8970000147819519},{"id":"https://openalex.org/keywords/tunica-propria","display_name":"tunica propria","score":0.8690000176429749},{"id":"https://openalex.org/keywords/basal-membrane","display_name":"basal membrane","score":0.6119999885559082},{"id":"https://openalex.org/keywords/reticular-fibers","display_name":"reticular fibers","score":0.800000011920929},{"id":"https://openalex.org/keywords/fibroblasts","display_name":"fibroblasts","score":0.8999999761581421},{"id":"https://openalex.org/keywords/testicular-biopsy","display_name":"testicular biopsy","score":0.5490000247955322}],"concepts":[{"id":"https://openalex.org/C518705261","wikidata":"https://www.wikidata.org/wiki/Q25615","display_name":"Connective tissue","level":2,"score":0.8127124905586243},{"id":"https://openalex.org/C95190701","wikidata":"https://www.wikidata.org/wiki/Q3268002","display_name":"Reticular connective tissue","level":2,"score":0.7500537037849426},{"id":"https://openalex.org/C2778803959","wikidata":"https://www.wikidata.org/wiki/Q4000449","display_name":"Tunica","level":2,"score":0.567684531211853},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5109526515007019},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.47125887870788574},{"id":"https://openalex.org/C26064473","wikidata":"https://www.wikidata.org/wiki/Q1539396","display_name":"Reticular fiber","level":2,"score":0.4668351411819458},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.45765507221221924},{"id":"https://openalex.org/C2780350170","wikidata":"https://www.wikidata.org/wiki/Q7853103","display_name":"Tunica albuginea (penis)","level":3,"score":0.428308367729187},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.41766273975372314},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3894340693950653},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.22418862581253052},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.210127055644989},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0},{"id":"https://openalex.org/C2777786686","wikidata":"https://www.wikidata.org/wiki/Q58","display_name":"Penis","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011627","descriptor_name":"Puberty","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012741","descriptor_name":"Sexual Maturation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1210/jcem-20-2-266","doi":"https://doi.org/10.1210/jcem-20-2-266","is_oa":false,"landing_page_url":"https://doi.org/10.1210/jcem-20-2-266","pdf_url":null,"source":{"id":"https://openalex.org/S205775358","display_name":"The Journal of Clinical Endocrinology & Metabolism","issn_l":"0021-972X","issn":["0021-972X","1945-7197"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Clinical Endocrinology & Metabolism","raw_type":"journal-article"},{"id":"pmid:13814792","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/13814792","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical endocrinology and metabolism","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.428600013256073,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2018954080","https://openalex.org/W7143668701","https://openalex.org/W35286394","https://openalex.org/W1975633739","https://openalex.org/W2746494450","https://openalex.org/W7028481131","https://openalex.org/W2520490068","https://openalex.org/W2772804103","https://openalex.org/W1965579492","https://openalex.org/W2345999671"],"abstract_inverted_index":{"A":[0,117],"histologic":[1,210],"study":[2],"was":[3,120,144,165],"made":[4],"of":[5,25,58,63,90,94,100,125,138,157,185,212,215],"testicular":[6,139,216],"biopsy":[7],"specimens":[8],"obtained":[9],"from":[10,39,167],"13":[11],"normal":[12,33,219],"youths":[13],"9":[14],"to":[15,21,171,177,183,228,240],"16":[16],"years":[17],"old,":[18],"in":[19,31,106,122,192,199],"order":[20],"determine":[22],"the":[23,26,32,36,46,61,71,87,101,123,126,136,141,151,160,193,200,209,213,235],"pattern":[24,225],"maturation":[27,140,217,242],"which":[28,79,227],"takes":[29],"place":[30],"testis":[34],"during":[35,218,243],"period":[37],"ranging":[38],"prepuberal":[40,169],"age":[41],"until":[42],"adulthood.":[43,83],"Observations":[44],"on":[45],"tubular":[47,49,102],"content,":[48],"wall":[50,103],"and":[51,73,76,114,133,175,203],"intertubular":[52,161,179],"connective":[53,162,180],"tissue,":[54,163,174],"indicated":[55],"three":[56,92,127],"degrees":[57],"maturation:":[59],"1)":[60],"beginning":[62],"puberal":[64,72],"development,":[65],"2)":[66],"an":[67,178,186],"intermediate":[68],"degree":[69,89],"between":[70],"adult":[74,187],"structure,":[75],"3)":[77],"testes":[78,85],"have":[80],"practically":[81],"reached":[82],"In":[84,135,159],"showing":[86],"first":[88],"maturation,":[91],"stages":[93],"lobular":[95],"evolution":[96],"were":[97],"observed.":[98],"Organization":[99],"became":[104],"manifest":[105],"two":[107],"well":[108,197],"differentiated":[109],"zones,":[110],"i.e.,":[111],"basal":[112],"membrane":[113],"tunica":[115],"propria.":[116],"definite":[118],"sequence":[119],"observed":[121,166],"development":[124],"component":[128],"parts:":[129],"amorphous":[130,142,201],"substance,":[131],"fibers":[132,148],"cells.":[134],"course":[137],"substance":[143,202],"replaced":[145],"by":[146],"reticular":[147],"and,":[149],"at":[150],"same":[152],"time,":[153],"fibroblasts":[154],"showed":[155],"signs":[156],"maturation.":[158],"transition":[164],"inactive":[168],"tissue":[170,181],"active":[172],"embryonic":[173],"subsequently":[176],"similar":[182],"that":[184],"testis.":[188],"These":[189,205],"changes":[190],"occurred":[191],"cellular":[194],"elements":[195],"as":[196,198,223],"fibers.":[204],"findings,":[206],"besides":[207],"demonstrating":[208],"characteristics":[211],"process":[214],"puberty,":[220],"should":[221],"serve":[222],"a":[224],"with":[226],"compare":[229],"histologically":[230],"abnormal":[231,241],"testes,":[232],"particularly":[233],"when":[234],"condition":[236],"may":[237],"be":[238],"due":[239],"puberty.":[244]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}