{"id":"https://openalex.org/W2000326606","doi":"https://doi.org/10.1515/cclm.2011.241","title":"Association of a functional polymorphism in the MMP7 gene promoter with susceptibility to vulnerable carotid plaque in a Han Chinese Population","display_name":"Association of a functional polymorphism in the MMP7 gene promoter with susceptibility to vulnerable carotid plaque in a Han Chinese Population","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2000326606","doi":"https://doi.org/10.1515/cclm.2011.241","mag":"2000326606","pmid":"https://pubmed.ncbi.nlm.nih.gov/21722074"},"language":"en","primary_location":{"id":"doi:10.1515/cclm.2011.241","doi":"https://doi.org/10.1515/cclm.2011.241","is_oa":false,"landing_page_url":"https://doi.org/10.1515/cclm.2011.241","pdf_url":null,"source":{"id":"https://openalex.org/S124948411","display_name":"Clinical Chemistry and Laboratory Medicine (CCLM)","issn_l":"1434-6621","issn":["1434-6621","1437-4331"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry and Laboratory Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070956358","display_name":"Xiaofei Hu","orcid":"https://orcid.org/0000-0001-5376-2779","observed_orcids":["https://orcid.org/0000-0001-5376-2779"]},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I4210158774","display_name":"Zhejiang Taizhou Hospital","ror":"https://ror.org/05m0wv206","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158774","https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao-Fei Hu","raw_affiliation_strings":["Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, PR China","institution_ids":["https://openalex.org/I27781120","https://openalex.org/I4210158774"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067703908","display_name":"Xiaoping Jin","orcid":"https://orcid.org/0000-0003-3593-5853","observed_orcids":["https://orcid.org/0000-0003-3593-5853"]},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiao-Ping Jin","raw_affiliation_strings":["Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China","institution_ids":["https://openalex.org/I27781120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102707621","display_name":"Pei-Yang Hu","orcid":"https://orcid.org/0000-0002-5468-7798","observed_orcids":["https://orcid.org/0000-0002-5468-7798"]},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pei-Yang Hu","raw_affiliation_strings":["Department of General Practice, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Practice, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China","institution_ids":["https://openalex.org/I27781120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021836486","display_name":"Min Sheng Zhu","orcid":"https://orcid.org/0000-0002-0706-6390","observed_orcids":["https://orcid.org/0000-0002-0706-6390"]},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Zhu","raw_affiliation_strings":["Public Laboratory, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Public Laboratory, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China","institution_ids":["https://openalex.org/I27781120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102803929","display_name":"Feng Wang","orcid":"https://orcid.org/0000-0002-8657-7753","observed_orcids":["https://orcid.org/0000-0002-8657-7753"]},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feng Wang","raw_affiliation_strings":["Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China","institution_ids":["https://openalex.org/I27781120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113642603","display_name":"Xian-fang Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xian-Fang Lin","raw_affiliation_strings":["Department of Ultrasound, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ultrasound, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China","institution_ids":["https://openalex.org/I27781120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021150663","display_name":"Weiling Li","orcid":"https://orcid.org/0000-0001-6681-9156","observed_orcids":["https://orcid.org/0000-0001-6681-9156","https://orcid.org/0009-0001-3708-0273"]},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei-Ling Li","raw_affiliation_strings":["Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China","institution_ids":["https://openalex.org/I27781120"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hong Ni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Ni","raw_affiliation_strings":["Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China","institution_ids":["https://openalex.org/I27781120"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101640656","display_name":"Lihua Yang","orcid":"https://orcid.org/0000-0002-0009-871X","observed_orcids":["https://orcid.org/0000-0002-0009-871X"]},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li-Hua Yang","raw_affiliation_strings":["Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Taizhou Hospital, Affiliated Hospital of Wenzhou Medical College, Taizhou, Zhejiang, P.R. China","institution_ids":["https://openalex.org/I27781120"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5067703908"],"corresponding_institution_ids":["https://openalex.org/I27781120"],"apc_list":{"value":2400,"currency":"EUR","value_usd":2712},"apc_paid":null,"fwci":0.6441,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.73859571,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"49","issue":"10","first_page":"1735","last_page":"41"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.8252000212669373,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.8252000212669373,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.08320000022649765,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.04540000110864639,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mmp-7","display_name":"MMP-7","score":0.8370000123977661},{"id":"https://openalex.org/keywords/matrix-metalloproteinase-7","display_name":"matrix metalloproteinase-7","score":0.9950000047683716},{"id":"https://openalex.org/keywords/promoter-polymorphism","display_name":"promoter polymorphism","score":0.9459999799728394},{"id":"https://openalex.org/keywords/vulnerable-carotid-plaque","display_name":"vulnerable carotid plaque","score":0.9789999723434448},{"id":"https://openalex.org/keywords/carotid-atherosclerosis","display_name":"carotid atherosclerosis","score":0.8650000095367432},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.968999981880188},{"id":"https://openalex.org/keywords/han-chinese","display_name":"Han Chinese","score":0.6809999942779541},{"id":"https://openalex.org/keywords/statin-therapy","display_name":"statin therapy","score":0.8420000076293945},{"id":"https://openalex.org/keywords/age-as-risk-factor","display_name":"age as risk factor","score":0.9539999961853027}],"concepts":[{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.772138237953186},{"id":"https://openalex.org/C2778710248","wikidata":"https://www.wikidata.org/wiki/Q17154669","display_name":"Vulnerable plaque","level":2,"score":0.7224180102348328},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.6303181052207947},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5429747700691223},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5292170643806458},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5131910443305969},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4894751310348511},{"id":"https://openalex.org/C149737253","wikidata":"https://www.wikidata.org/wiki/Q3240252","display_name":"Polymorphism (computer science)","level":4,"score":0.4509146809577942},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.4194600582122803},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3781825304031372},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30546098947525024},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.26367831230163574},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22379574179649353}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020783","descriptor_name":"Matrix Metalloproteinase 7","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D044466","descriptor_name":"Asian People","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D058226","descriptor_name":"Plaque, Atherosclerotic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1515/cclm.2011.241","doi":"https://doi.org/10.1515/cclm.2011.241","is_oa":false,"landing_page_url":"https://doi.org/10.1515/cclm.2011.241","pdf_url":null,"source":{"id":"https://openalex.org/S124948411","display_name":"Clinical Chemistry and Laboratory Medicine (CCLM)","issn_l":"1434-6621","issn":["1434-6621","1437-4331"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry and Laboratory Medicine","raw_type":"journal-article"},{"id":"pmid:21722074","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21722074","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical chemistry and laboratory medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320338464","display_name":"Natural Science Foundation of Zhejiang Province","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1488829562","https://openalex.org/W1493755221","https://openalex.org/W1934785904","https://openalex.org/W1976537349","https://openalex.org/W1979226284","https://openalex.org/W1982399072","https://openalex.org/W1991398445","https://openalex.org/W1997216053","https://openalex.org/W2004260875","https://openalex.org/W2012105257","https://openalex.org/W2017598386","https://openalex.org/W2027872594","https://openalex.org/W2032806953","https://openalex.org/W2037033559","https://openalex.org/W2037141618","https://openalex.org/W2040393298","https://openalex.org/W2043804201","https://openalex.org/W2062870312","https://openalex.org/W2071359561","https://openalex.org/W2079820607","https://openalex.org/W2095928540","https://openalex.org/W2097279828","https://openalex.org/W2104193952","https://openalex.org/W2110667456","https://openalex.org/W2116728322","https://openalex.org/W2121311096","https://openalex.org/W2122574397","https://openalex.org/W2125530801","https://openalex.org/W2138984008","https://openalex.org/W2139889359","https://openalex.org/W2141224591","https://openalex.org/W2149545865","https://openalex.org/W2157006649","https://openalex.org/W2157732983","https://openalex.org/W2158653931","https://openalex.org/W2159064660","https://openalex.org/W2165154997","https://openalex.org/W2165351280","https://openalex.org/W3031276683","https://openalex.org/W4296979652"],"related_works":["https://openalex.org/W3030887689","https://openalex.org/W2156954568","https://openalex.org/W1976594925","https://openalex.org/W2366414306","https://openalex.org/W2903151431","https://openalex.org/W1979793161","https://openalex.org/W3193918749","https://openalex.org/W2114306699","https://openalex.org/W7002056908","https://openalex.org/W1997216053"],"abstract_inverted_index":{"BACKGROUND:":[0],"Matrix":[1],"metalloproteinase-7":[2],"(MMP-7)":[3],"may":[4],"play":[5],"an":[6],"important":[7],"role":[8],"in":[9,20,28,148],"the":[10,21,32,36,46,49,72,96,111,118,140,149,169,181,215],"development":[11,216],"of":[12,24,35,40,142,171,196,217,238],"vulnerable":[13,54,76,150,184,193,218],"carotid":[14,55,73,130,219,239],"plaque.":[15,173],"An":[16],"A-to-G":[17],"transition":[18],"(-181A/G)":[19],"promoter":[22],"region":[23],"MMP7":[25,50,97,125,188,209],"is":[26,212,222,232],"functional":[27],"vitro":[29],"by":[30,102],"altering":[31],"transcriptional":[33],"activity":[34],"gene.":[37],"The":[38,59,208],"aim":[39],"this":[41,187],"study":[42],"was":[43,100,132,145,157,190],"to":[44,71,117],"investigate":[45],"association":[47],"between":[48,124,180],"-181A/G":[51,98,210],"polymorphism":[52,99,189,211],"and":[53,64,84,95,128,183],"plaque":[56,77,81,86,120,131,151,162,185,194,227],"formation.":[57],"METHODS:":[58],"authors":[60],"enrolled":[61],"641":[62],"patients":[63],"divided":[65],"them":[66],"into":[67],"three":[68],"groups":[69],"according":[70],"ultrasound":[74],"examination:":[75],"group":[78,82,87,152],"(n=118),":[79],"stable":[80,129,182],"(n=385)":[83],"no":[85,119,122],"(n=138).":[88],"Traditional":[89],"atherosclerosis":[90],"risk":[91,159,224],"factors":[92,198],"were":[93],"recorded":[94],"genotyped":[101],"polymerase":[103],"chain":[104],"reaction-restriction":[105],"fragment":[106],"length":[107],"polymorphism.":[108],"RESULTS:":[109],"In":[110],"multinomial":[112],"logistic":[113,177],"regression":[114,178],"analysis,":[115],"compared":[116],"group,":[121],"relationship":[123],"-181AG+GG":[126],"genotypes":[127,144],"observed":[133],"[odds":[134],"ratio":[135],"(OR)":[136],"1.50;":[137],"p=0.239].":[138],"However,":[139],"frequency":[141],"AG+GG":[143],"significantly":[146],"higher":[147],"(OR":[153],"2.74;":[154],"p=0.008).":[155],"Age":[156,221],"a":[158,223,235],"factor":[160,225],"for":[161,226],"formation,":[163,228],"while":[164,229],"statin":[165,230],"treatment":[166],"can":[167],"reduce":[168],"prevalence":[170,237],"atherosclerotic":[172],"Additionally,":[174],"using":[175],"binary":[176],"analysis":[179],"groups,":[186],"associated":[191,213,233],"with":[192,214,234],"independently":[195],"other":[197],"[OR":[199],"1.83;":[200],"95%":[201],"confidence":[202],"interval":[203],"1.08-":[204],"3.11;":[205],"p=0.026].":[206],"CONCLUSIONS:":[207],"plaques.":[220,241],"therapy":[231],"decreased":[236],"atheromatous":[240]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}