{"id":"https://openalex.org/W2000304408","doi":"https://doi.org/10.1016/s0167-4889(00)00132-4","title":"Free leucine dissociates homo- and heterodimers formed between proteins containing leucine heptad repeats","display_name":"Free leucine dissociates homo- and heterodimers formed between proteins containing leucine heptad repeats","publication_year":2001,"publication_date":"2001-01-01","ids":{"openalex":"https://openalex.org/W2000304408","doi":"https://doi.org/10.1016/s0167-4889(00)00132-4","mag":"2000304408","pmid":"https://pubmed.ncbi.nlm.nih.gov/11341964"},"language":"en","primary_location":{"id":"doi:10.1016/s0167-4889(00)00132-4","doi":"https://doi.org/10.1016/s0167-4889(00)00132-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0167-4889(00)00132-4","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0167488900001324/pdf","source":{"id":"https://openalex.org/S4210226410","display_name":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","issn_l":"0167-4889","issn":["0167-4889","1879-2596"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S0167488900001324/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086982875","display_name":"Putu Khrisna Dharma Jaya","orcid":"https://orcid.org/0009-0004-6502-6030","observed_orcids":["https://orcid.org/0009-0004-6502-6030"]},"institutions":[{"id":"https://openalex.org/I89324447","display_name":"Rajiv Gandhi Centre for Biotechnology","ror":"https://ror.org/05sdqd547","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I89324447"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"P. Jaya","raw_affiliation_strings":["Rajiv Gandhi Centre for Biotechnology, Jagathy, Thiruvananthapuram 695 014, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rajiv Gandhi Centre for Biotechnology, Jagathy, Thiruvananthapuram 695 014, Kerala, India","institution_ids":["https://openalex.org/I89324447"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M. Premkumar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36893310","display_name":"University of Hyderabad","ror":"https://ror.org/04a7rxb17","country_code":"IN","type":"education","lineage":["https://openalex.org/I36893310"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"M. Premkumar","raw_affiliation_strings":["Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad 500 046, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad 500 046, India","institution_ids":["https://openalex.org/I36893310"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062724249","display_name":"Raghava Varman Thampan","orcid":"https://orcid.org/0000-0002-5100-8518","observed_orcids":["https://orcid.org/0000-0002-5100-8518"]},"institutions":[{"id":"https://openalex.org/I89324447","display_name":"Rajiv Gandhi Centre for Biotechnology","ror":"https://ror.org/05sdqd547","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I89324447"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Raghava Varman Thampan","raw_affiliation_strings":["Rajiv Gandhi Centre for Biotechnology, Jagathy, Thiruvananthapuram 695 014, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rajiv Gandhi Centre for Biotechnology, Jagathy, Thiruvananthapuram 695 014, Kerala, India","institution_ids":["https://openalex.org/I89324447"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5062724249"],"corresponding_institution_ids":["https://openalex.org/I89324447"],"apc_list":{"value":3930,"currency":"USD","value_usd":3930},"apc_paid":null,"fwci":0.2168,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.40031729,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"1499","issue":"3","first_page":"171","last_page":"179"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.9032999873161316,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.9032999873161316,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.05009999871253967,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.008899999782443047,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-dimer-dissociation","display_name":"protein dimer dissociation","score":0.8700000047683716},{"id":"https://openalex.org/keywords/leucine-zipper","display_name":"leucine zipper","score":0.8709999918937683},{"id":"https://openalex.org/keywords/coiled-coil-dimerization","display_name":"coiled-coil dimerization","score":0.890999972820282},{"id":"https://openalex.org/keywords/oestrogen-receptor","display_name":"oestrogen receptor","score":0.7549999952316284},{"id":"https://openalex.org/keywords/c-jun","display_name":"c-Jun","score":0.8640000224113464},{"id":"https://openalex.org/keywords/c-fos","display_name":"c-fos","score":0.9810000061988831},{"id":"https://openalex.org/keywords/glucocorticoid-receptor","display_name":"glucocorticoid receptor","score":0.9869999885559082},{"id":"https://openalex.org/keywords/steroid-hormone-receptors","display_name":"steroid hormone receptors","score":0.9660000205039978},{"id":"https://openalex.org/keywords/oncoprotein","display_name":"oncoprotein","score":0.9409999847412109}],"concepts":[{"id":"https://openalex.org/C156860981","wikidata":"https://www.wikidata.org/wiki/Q2565229","display_name":"Leucine zipper","level":4,"score":0.9164837598800659},{"id":"https://openalex.org/C122146531","wikidata":"https://www.wikidata.org/wiki/Q16920125","display_name":"Heptad repeat","level":4,"score":0.8191009759902954},{"id":"https://openalex.org/C2776580952","wikidata":"https://www.wikidata.org/wiki/Q483745","display_name":"Leucine","level":3,"score":0.6316808462142944},{"id":"https://openalex.org/C2779546866","wikidata":"https://www.wikidata.org/wiki/Q531306","display_name":"Dimer","level":2,"score":0.6273242235183716},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6014131903648376},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5758647322654724},{"id":"https://openalex.org/C55988834","wikidata":"https://www.wikidata.org/wiki/Q903650","display_name":"Coiled coil","level":2,"score":0.5749446749687195},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4931037127971649},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36422133445739746},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.337322473526001},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3369898200035095},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.25865834951400757},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.24401786923408508},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1801758110523224},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007930","descriptor_name":"Leucine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011960","descriptor_name":"Receptors, Estrogen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011965","descriptor_name":"Receptors, Glucocorticoid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014599","descriptor_name":"Uterus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016350","descriptor_name":"Leucine Zippers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016755","descriptor_name":"Proto-Oncogene Proteins c-jun","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019281","descriptor_name":"Dimerization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020836","descriptor_name":"Protein Structure, Quaternary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0167-4889(00)00132-4","doi":"https://doi.org/10.1016/s0167-4889(00)00132-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0167-4889(00)00132-4","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0167488900001324/pdf","source":{"id":"https://openalex.org/S4210226410","display_name":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","issn_l":"0167-4889","issn":["0167-4889","1879-2596"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","raw_type":"journal-article"},{"id":"pmid:11341964","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11341964","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0167-4889(00)00132-4","doi":"https://doi.org/10.1016/s0167-4889(00)00132-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0167-4889(00)00132-4","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0167488900001324/pdf","source":{"id":"https://openalex.org/S4210226410","display_name":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","issn_l":"0167-4889","issn":["0167-4889","1879-2596"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2000304408.pdf","grobid_xml":"https://content.openalex.org/works/W2000304408.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1545434430","https://openalex.org/W1605399271","https://openalex.org/W1931164952","https://openalex.org/W1968238528","https://openalex.org/W1976091857","https://openalex.org/W1995135269","https://openalex.org/W2005393972","https://openalex.org/W2005631749","https://openalex.org/W2007385914","https://openalex.org/W2010822247","https://openalex.org/W2014107736","https://openalex.org/W2037145628","https://openalex.org/W2039478144","https://openalex.org/W2043493577","https://openalex.org/W2044402272","https://openalex.org/W2044853699","https://openalex.org/W2051181331","https://openalex.org/W2055290772","https://openalex.org/W2086607694","https://openalex.org/W2100601849","https://openalex.org/W2100837269","https://openalex.org/W2101108802","https://openalex.org/W2115311570","https://openalex.org/W2132781864","https://openalex.org/W2158392767"],"related_works":["https://openalex.org/W2007468038","https://openalex.org/W2161181927","https://openalex.org/W2010942772","https://openalex.org/W2068365494","https://openalex.org/W2078378921","https://openalex.org/W2164464592","https://openalex.org/W2315494976","https://openalex.org/W4247646032","https://openalex.org/W1604014255","https://openalex.org/W1988350384"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}