{"id":"https://openalex.org/W2000298215","doi":"https://doi.org/10.1007/s00535-007-2099-8","title":"Pretreatment predictor of response, time to progression, and survival to intraarterial 5-fluorouracil/interferon combination therapy in patients with advanced hepatocellular carcinoma","display_name":"Pretreatment predictor of response, time to progression, and survival to intraarterial 5-fluorouracil/interferon combination therapy in patients with advanced hepatocellular carcinoma","publication_year":2007,"publication_date":"2007-10-15","ids":{"openalex":"https://openalex.org/W2000298215","doi":"https://doi.org/10.1007/s00535-007-2099-8","mag":"2000298215","pmid":"https://pubmed.ncbi.nlm.nih.gov/17940838"},"language":"en","primary_location":{"id":"doi:10.1007/s00535-007-2099-8","doi":"https://doi.org/10.1007/s00535-007-2099-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00535-007-2099-8","pdf_url":null,"source":{"id":"https://openalex.org/S41046285","display_name":"Journal of Gastroenterology","issn_l":"0944-1174","issn":["0944-1174","1435-5922"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022256896","display_name":"Kiminori Uka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kiminori Uka","raw_affiliation_strings":["Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Hiroshima 734-8551, Japan","Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Hiroshima 734-8551, Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037963685","display_name":"Hiroshi Aikata","orcid":"https://orcid.org/0000-0002-3409-2156","observed_orcids":["https://orcid.org/0000-0002-3409-2156"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Aikata","raw_affiliation_strings":["Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112553834","display_name":"Shintaro Takaki","orcid":"https://orcid.org/0000-0002-8492-5339","observed_orcids":["https://orcid.org/0000-0002-8492-5339"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shintaro Takaki","raw_affiliation_strings":["Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044269436","display_name":"Daiki Miki","orcid":"https://orcid.org/0000-0002-6505-9826","observed_orcids":["https://orcid.org/0000-0002-6505-9826"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Daiki Miki","raw_affiliation_strings":["Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031469873","display_name":"Tomokazu Kawaoka","orcid":"https://orcid.org/0000-0002-1887-1096","observed_orcids":["https://orcid.org/0000-0002-1887-1096"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomokazu Kawaoka","raw_affiliation_strings":["Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057420745","display_name":"Soo Cheol Jeong","orcid":"https://orcid.org/0000-0003-2050-5156","observed_orcids":["https://orcid.org/0000-0003-2050-5156"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Soo Cheol Jeong","raw_affiliation_strings":["Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109890395","display_name":"Shoichi Takahashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shoichi Takahashi","raw_affiliation_strings":["Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110521023","display_name":"Naoyuki Toyota","orcid":"https://orcid.org/0009-0004-0621-4883","observed_orcids":["https://orcid.org/0009-0004-0621-4883"]},"institutions":[{"id":"https://openalex.org/I4210125056","display_name":"Hiroshima University Hospital","ror":"https://ror.org/038dg9e86","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoyuki Toyota","raw_affiliation_strings":["Department of Radiology, Hiroshima University Hospital, Hiroshima, Japan","Hiroshima University Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Hiroshima University Hospital, Hiroshima, Japan","institution_ids":["https://openalex.org/I4210125056"]},{"raw_affiliation_string":"Hiroshima University Hospital","institution_ids":["https://openalex.org/I4210125056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109983271","display_name":"Katsuhide Ito","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125056","display_name":"Hiroshima University Hospital","ror":"https://ror.org/038dg9e86","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuhide Ito","raw_affiliation_strings":["Department of Radiology, Hiroshima University Hospital, Hiroshima, Japan","Hiroshima University Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Hiroshima University Hospital, Hiroshima, Japan","institution_ids":["https://openalex.org/I4210125056"]},{"raw_affiliation_string":"Hiroshima University Hospital","institution_ids":["https://openalex.org/I4210125056"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023958825","display_name":"Kazuaki Chayama","orcid":"https://orcid.org/0000-0002-5530-5341","observed_orcids":["https://orcid.org/0000-0002-5530-5341"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuaki Chayama","raw_affiliation_strings":["Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University","institution_ids":["https://openalex.org/I113306721"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5290,"currency":"USD","value_usd":5290},"apc_paid":null,"fwci":2.6243,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.88893044,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"42","issue":"10","first_page":"845","last_page":"853"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.9670000076293945},{"id":"https://openalex.org/keywords/interferon-alpha","display_name":"interferon-alpha","score":0.9639999866485596},{"id":"https://openalex.org/keywords/portal-vein-tumor-thrombus","display_name":"portal vein tumor thrombus","score":0.9810000061988831},{"id":"https://openalex.org/keywords/anti-hcv-antibodies","display_name":"anti-HCV antibodies","score":0.6859999895095825},{"id":"https://openalex.org/keywords/predictive-factors","display_name":"predictive factors","score":0.6110000014305115},{"id":"https://openalex.org/keywords/treatment-response","display_name":"treatment response","score":0.8849999904632568},{"id":"https://openalex.org/keywords/time-to-progression","display_name":"time to progression","score":0.9909999966621399},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.9810000061988831},{"id":"https://openalex.org/keywords/performance-status","display_name":"performance status","score":0.8399999737739563},{"id":"https://openalex.org/keywords/complete-response","display_name":"complete response","score":0.4429999887943268},{"id":"https://openalex.org/keywords/partial-response","display_name":"partial response","score":0.42899999022483826}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8954267501831055},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.7700191736221313},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7462142705917358},{"id":"https://openalex.org/C2776999253","wikidata":"https://www.wikidata.org/wiki/Q1304270","display_name":"Combination therapy","level":2,"score":0.6618942618370056},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.620018720626831},{"id":"https://openalex.org/C2780140570","wikidata":"https://www.wikidata.org/wiki/Q3545481","display_name":"Surgical oncology","level":2,"score":0.5674993991851807},{"id":"https://openalex.org/C2780456651","wikidata":"https://www.wikidata.org/wiki/Q238512","display_name":"Fluorouracil","level":3,"score":0.5241872668266296},{"id":"https://openalex.org/C2776408679","wikidata":"https://www.wikidata.org/wiki/Q708693","display_name":"Hepatitis C virus","level":3,"score":0.49895811080932617},{"id":"https://openalex.org/C41260117","wikidata":"https://www.wikidata.org/wiki/Q668064","display_name":"Hepatology","level":2,"score":0.49520793557167053},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4671190679073334},{"id":"https://openalex.org/C144301174","wikidata":"https://www.wikidata.org/wiki/Q7893852","display_name":"Univariate analysis","level":3,"score":0.4633271098136902},{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.4301660656929016},{"id":"https://openalex.org/C2778822529","wikidata":"https://www.wikidata.org/wiki/Q1951525","display_name":"Progressive disease","level":3,"score":0.4200867712497711},{"id":"https://openalex.org/C2778800853","wikidata":"https://www.wikidata.org/wiki/Q1704044","display_name":"Portal vein thrombosis","level":3,"score":0.4164016842842102},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3587818741798401},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.32001638412475586},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3026468753814697},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.2738564908504486},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.2530253529548645},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.15136900544166565}],"mesh":[{"descriptor_ui":"D000077190","descriptor_name":"Interferon alpha-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005472","descriptor_name":"Fluorouracil","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007261","descriptor_name":"Infusions, Intra-Arterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011169","descriptor_name":"Portal Vein","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016898","descriptor_name":"Interferon-alpha","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018937","descriptor_name":"Hepatitis C Antibodies","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D020246","descriptor_name":"Venous Thrombosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00535-007-2099-8","doi":"https://doi.org/10.1007/s00535-007-2099-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00535-007-2099-8","pdf_url":null,"source":{"id":"https://openalex.org/S41046285","display_name":"Journal of Gastroenterology","issn_l":"0944-1174","issn":["0944-1174","1435-5922"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Gastroenterology","raw_type":"journal-article"},{"id":"pmid:17940838","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17940838","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of gastroenterology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1552290465","https://openalex.org/W1979667390","https://openalex.org/W1986534365","https://openalex.org/W1988843250","https://openalex.org/W2000314084","https://openalex.org/W2009435220","https://openalex.org/W2016018273","https://openalex.org/W2024126773","https://openalex.org/W2024802373","https://openalex.org/W2049812177","https://openalex.org/W2075942495","https://openalex.org/W2076668534","https://openalex.org/W2081222934","https://openalex.org/W2083803103","https://openalex.org/W2096797256","https://openalex.org/W2102240822","https://openalex.org/W2105342721","https://openalex.org/W2124948463","https://openalex.org/W2134596275","https://openalex.org/W2139248078","https://openalex.org/W2148575952","https://openalex.org/W2163557371","https://openalex.org/W2591170673","https://openalex.org/W2767729710","https://openalex.org/W4297888650"],"related_works":["https://openalex.org/W2589478489","https://openalex.org/W1535305783","https://openalex.org/W2133302868","https://openalex.org/W2024802373","https://openalex.org/W1483980368","https://openalex.org/W2090262993","https://openalex.org/W3000211261","https://openalex.org/W2030511252","https://openalex.org/W2099413737","https://openalex.org/W3146718046"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}