{"id":"https://openalex.org/W2000277875","doi":"https://doi.org/10.1016/j.bbagen.2014.05.021","title":"Bacteriorhodopsin: Would the real structural intermediates please stand up?","display_name":"Bacteriorhodopsin: Would the real structural intermediates please stand up?","publication_year":2014,"publication_date":"2014-06-08","ids":{"openalex":"https://openalex.org/W2000277875","doi":"https://doi.org/10.1016/j.bbagen.2014.05.021","mag":"2000277875","pmid":"https://pubmed.ncbi.nlm.nih.gov/24918316"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbagen.2014.05.021","doi":"https://doi.org/10.1016/j.bbagen.2014.05.021","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbagen.2014.05.021","pdf_url":null,"source":{"id":"https://openalex.org/S4210238601","display_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","issn_l":"0304-4165","issn":["0304-4165","1872-8006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.bbagen.2014.05.021","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043617948","display_name":"Cecilia Wickstrand","orcid":"https://orcid.org/0009-0003-1366-5140","observed_orcids":["https://orcid.org/0009-0003-1366-5140"]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Cecilia Wickstrand","raw_affiliation_strings":["Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-40530 Gothenburg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-40530 Gothenburg, Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044448446","display_name":"Robert H. Dods","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Robert Dods","raw_affiliation_strings":["Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-40530 Gothenburg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-40530 Gothenburg, Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011809219","display_name":"Antoine Royant","orcid":"https://orcid.org/0000-0002-1919-8649","observed_orcids":["https://orcid.org/0000-0002-1919-8649"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I2801997478","display_name":"European Synchrotron Radiation Facility","ror":"https://ror.org/02550n020","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801997478"]},{"id":"https://openalex.org/I3020098449","display_name":"CEA Grenoble","ror":"https://ror.org/02mg6n827","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I3020098449"]},{"id":"https://openalex.org/I4210152516","display_name":"Institut de Biologie Structurale","ror":"https://ror.org/04szabx38","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I2738703131","https://openalex.org/I4210091409","https://openalex.org/I4210096427","https://openalex.org/I4210113668","https://openalex.org/I4210152516","https://openalex.org/I899635006"]},{"id":"https://openalex.org/I899635006","display_name":"Universit\u00e9 Grenoble Alpes","ror":"https://ror.org/02rx3b187","country_code":"FR","type":"education","lineage":["https://openalex.org/I899635006"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Antoine Royant","raw_affiliation_strings":["Univ. Grenoble Alpes, IBS, F-38044 Grenoble, France; CNRS, IBS, F-38044 Grenoble, France; CEA, IBS, F-38044 Grenoble, France; European Synchrotron Radiation Facility, F-38043 Grenoble, France. Electronic address: antoine.royant@ibs.fr","CEA, IBS, F-38044 Grenoble, France","CNRS, IBS, F-38044 Grenoble, France","European Synchrotron Radiation Facility, F-38043 Grenoble, France","Univ. Grenoble Alpes, IBS, F-38044 Grenoble, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Grenoble Alpes, IBS, F-38044 Grenoble, France; CNRS, IBS, F-38044 Grenoble, France; CEA, IBS, F-38044 Grenoble, France; European Synchrotron Radiation Facility, F-38043 Grenoble, France. Electronic address: antoine.royant@ibs.fr","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I2738703131","https://openalex.org/I2801997478","https://openalex.org/I4210152516","https://openalex.org/I899635006"]},{"raw_affiliation_string":"CEA, IBS, F-38044 Grenoble, France","institution_ids":["https://openalex.org/I2738703131","https://openalex.org/I3020098449","https://openalex.org/I4210152516"]},{"raw_affiliation_string":"CNRS, IBS, F-38044 Grenoble, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210152516"]},{"raw_affiliation_string":"European Synchrotron Radiation Facility, F-38043 Grenoble, France","institution_ids":["https://openalex.org/I2801997478"]},{"raw_affiliation_string":"Univ. Grenoble Alpes, IBS, F-38044 Grenoble, France","institution_ids":["https://openalex.org/I4210152516","https://openalex.org/I899635006"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017316562","display_name":"Richard Neutze","orcid":"https://orcid.org/0000-0003-0986-6153","observed_orcids":["https://orcid.org/0000-0003-0986-6153"]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Richard Neutze","raw_affiliation_strings":["Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-40530 Gothenburg, Sweden. Electronic address: richard.neutze@chem.gu.se","Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-40530 Gothenburg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-40530 Gothenburg, Sweden. Electronic address: richard.neutze@chem.gu.se","institution_ids":["https://openalex.org/I881427289"]},{"raw_affiliation_string":"Department of Chemistry and Molecular Biology, University of Gothenburg, Box 462, SE-40530 Gothenburg, Sweden","institution_ids":["https://openalex.org/I881427289"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5011809219","https://openalex.org/A5017316562"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I2738703131","https://openalex.org/I2801997478","https://openalex.org/I3020098449","https://openalex.org/I4210152516","https://openalex.org/I881427289","https://openalex.org/I899635006"],"apc_list":{"value":3310,"currency":"USD","value_usd":3310},"apc_paid":{"value":3310,"currency":"USD","value_usd":3310},"fwci":1.0969,"has_fulltext":false,"cited_by_count":125,"citation_normalized_percentile":{"value":0.71191136,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"1850","issue":"3","first_page":"536","last_page":"553"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bacteriorhodopsin","display_name":"bacteriorhodopsin","score":1.0},{"id":"https://openalex.org/keywords/photoinduced-structural-changes","display_name":"light-induced structural changes","score":0.925000011920929},{"id":"https://openalex.org/keywords/light-driven-proton-pump","display_name":"light-driven proton pump","score":0.8180000185966492},{"id":"https://openalex.org/keywords/retinal-schiff-base","display_name":"retinal Schiff base","score":0.718999981880188},{"id":"https://openalex.org/keywords/asp85","display_name":"Asp85","score":0.7129999995231628},{"id":"https://openalex.org/keywords/helix-c","display_name":"helix C","score":0.4309999942779541},{"id":"https://openalex.org/keywords/f-helix","display_name":"helix F","score":0.9430000185966492},{"id":"https://openalex.org/keywords/radiation-damage","display_name":"radiation damage","score":0.656000018119812},{"id":"https://openalex.org/keywords/crystal-forms","display_name":"crystal forms","score":0.32499998807907104},{"id":"https://openalex.org/keywords/membrane-protein-structure","display_name":"membrane protein structure","score":0.6230000257492065}],"concepts":[{"id":"https://openalex.org/C189542057","wikidata":"https://www.wikidata.org/wiki/Q242310","display_name":"Bacteriorhodopsin","level":3,"score":0.9104049205780029},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.712134599685669},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5869677662849426},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.5238929986953735},{"id":"https://openalex.org/C2778530040","wikidata":"https://www.wikidata.org/wiki/Q1937315","display_name":"Helix (gastropod)","level":3,"score":0.5068498253822327},{"id":"https://openalex.org/C115624301","wikidata":"https://www.wikidata.org/wiki/Q895901","display_name":"Crystal structure","level":2,"score":0.504574179649353},{"id":"https://openalex.org/C119145174","wikidata":"https://www.wikidata.org/wiki/Q7251429","display_name":"Protein Data Bank","level":3,"score":0.4762323498725891},{"id":"https://openalex.org/C50515024","wikidata":"https://www.wikidata.org/wiki/Q826582","display_name":"X-ray crystallography","level":3,"score":0.4716828465461731},{"id":"https://openalex.org/C203036418","wikidata":"https://www.wikidata.org/wiki/Q284256","display_name":"Crystallization","level":2,"score":0.4716106057167053},{"id":"https://openalex.org/C207114421","wikidata":"https://www.wikidata.org/wiki/Q133900","display_name":"Diffraction","level":2,"score":0.4434175491333008},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.4242573082447052},{"id":"https://openalex.org/C153064111","wikidata":"https://www.wikidata.org/wiki/Q1281033","display_name":"Protein crystallization","level":3,"score":0.41523852944374084},{"id":"https://openalex.org/C2776428424","wikidata":"https://www.wikidata.org/wiki/Q2602701","display_name":"Schiff base","level":2,"score":0.4132188558578491},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1607995331287384},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.12518897652626038},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C2779965526","wikidata":"https://www.wikidata.org/wiki/Q308841","display_name":"Snail","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001436","descriptor_name":"Bacteriorhodopsins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001436","descriptor_name":"Bacteriorhodopsins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001436","descriptor_name":"Bacteriorhodopsins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D014965","descriptor_name":"X-Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bbagen.2014.05.021","doi":"https://doi.org/10.1016/j.bbagen.2014.05.021","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbagen.2014.05.021","pdf_url":null,"source":{"id":"https://openalex.org/S4210238601","display_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","issn_l":"0304-4165","issn":["0304-4165","1872-8006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","raw_type":"journal-article"},{"id":"pmid:24918316","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24918316","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-01131847v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-01131847v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BBA - Biochimica et Biophysica Acta, 2015, 1850 (3), pp.536-553","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.bbagen.2014.05.021","doi":"https://doi.org/10.1016/j.bbagen.2014.05.021","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbagen.2014.05.021","pdf_url":null,"source":{"id":"https://openalex.org/S4210238601","display_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","issn_l":"0304-4165","issn":["0304-4165","1872-8006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G6441358319","display_name":"Singlet oxygen: from damage to proteins to the development of biosensors and generators","funder_award_id":"ANR-11-JSV5-0009","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320320940","display_name":"Stiftelsen f\u00f6r\u00a0Strategisk Forskning","ror":"https://ror.org/044wr7g58"},{"id":"https://openalex.org/F4320322327","display_name":"Knut och Alice Wallenbergs Stiftelse","ror":"https://ror.org/004hzzk67"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320327257","display_name":"Stiftelsen f\u00f6r Strategisk Forskning","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":128,"referenced_works":["https://openalex.org/W46156237","https://openalex.org/W72657818","https://openalex.org/W162442128","https://openalex.org/W257446291","https://openalex.org/W1508315241","https://openalex.org/W1578292667","https://openalex.org/W1586792701","https://openalex.org/W1594929565","https://openalex.org/W1620064517","https://openalex.org/W1785940294","https://openalex.org/W1825353903","https://openalex.org/W1832700322","https://openalex.org/W1907544268","https://openalex.org/W1942533571","https://openalex.org/W1963480398","https://openalex.org/W1968458945","https://openalex.org/W1968960649","https://openalex.org/W1970538439","https://openalex.org/W1972014516","https://openalex.org/W1972563656","https://openalex.org/W1973881708","https://openalex.org/W1974224535","https://openalex.org/W1975934353","https://openalex.org/W1977464493","https://openalex.org/W1977569471","https://openalex.org/W1978886142","https://openalex.org/W1979565363","https://openalex.org/W1984660994","https://openalex.org/W1986789979","https://openalex.org/W1987418575","https://openalex.org/W1988097700","https://openalex.org/W1990798950","https://openalex.org/W1994152613","https://openalex.org/W1997263768","https://openalex.org/W1999768562","https://openalex.org/W2004929882","https://openalex.org/W2009038821","https://openalex.org/W2010622172","https://openalex.org/W2012670872","https://openalex.org/W2014445498","https://openalex.org/W2016066619","https://openalex.org/W2016237935","https://openalex.org/W2017393510","https://openalex.org/W2017668510","https://openalex.org/W2019306938","https://openalex.org/W2020465369","https://openalex.org/W2021661744","https://openalex.org/W2024741993","https://openalex.org/W2030175542","https://openalex.org/W2033783558","https://openalex.org/W2034397295","https://openalex.org/W2036862423","https://openalex.org/W2037779370","https://openalex.org/W2041256732","https://openalex.org/W2045130774","https://openalex.org/W2048695489","https://openalex.org/W2050292589","https://openalex.org/W2050421068","https://openalex.org/W2051068302","https://openalex.org/W2051956840","https://openalex.org/W2054091316","https://openalex.org/W2054288728","https://openalex.org/W2055425903","https://openalex.org/W2056316643","https://openalex.org/W2056641846","https://openalex.org/W2058209954","https://openalex.org/W2059043635","https://openalex.org/W2062021082","https://openalex.org/W2062930912","https://openalex.org/W2064497637","https://openalex.org/W2067079920","https://openalex.org/W2067841258","https://openalex.org/W2069238522","https://openalex.org/W2069339217","https://openalex.org/W2069696932","https://openalex.org/W2072405301","https://openalex.org/W2072962112","https://openalex.org/W2073272276","https://openalex.org/W2074062743","https://openalex.org/W2075592322","https://openalex.org/W2076057575","https://openalex.org/W2077431803","https://openalex.org/W2080231167","https://openalex.org/W2081252646","https://openalex.org/W2081417841","https://openalex.org/W2085191928","https://openalex.org/W2093562743","https://openalex.org/W2104477830","https://openalex.org/W2104675030","https://openalex.org/W2108455349","https://openalex.org/W2110810808","https://openalex.org/W2111995968","https://openalex.org/W2115357061","https://openalex.org/W2115391980","https://openalex.org/W2115932892","https://openalex.org/W2117444466","https://openalex.org/W2119221730","https://openalex.org/W2123323202","https://openalex.org/W2125289895","https://openalex.org/W2127395373","https://openalex.org/W2127432350","https://openalex.org/W2129141040","https://openalex.org/W2133000192","https://openalex.org/W2133283923","https://openalex.org/W2134278392","https://openalex.org/W2138910888","https://openalex.org/W2141365730","https://openalex.org/W2142722662","https://openalex.org/W2143015200","https://openalex.org/W2149076987","https://openalex.org/W2149192805","https://openalex.org/W2149705812","https://openalex.org/W2151971205","https://openalex.org/W2152668682","https://openalex.org/W2153061750","https://openalex.org/W2155027540","https://openalex.org/W2156004732","https://openalex.org/W2156395200","https://openalex.org/W2156618418","https://openalex.org/W2156759934","https://openalex.org/W2159059233","https://openalex.org/W2159477987","https://openalex.org/W2161475887","https://openalex.org/W2166189591","https://openalex.org/W2171777099","https://openalex.org/W2769575965","https://openalex.org/W2788963310","https://openalex.org/W4236397303"],"related_works":["https://openalex.org/W2072405301","https://openalex.org/W2777537360","https://openalex.org/W2063018558","https://openalex.org/W3035890317","https://openalex.org/W2888788869","https://openalex.org/W6982595383","https://openalex.org/W7097931068","https://openalex.org/W1026780910","https://openalex.org/W2153061750","https://openalex.org/W7099090511"],"abstract_inverted_index":{"BACKGROUND:":[0],"Bacteriorhodopsin":[1],"(bR)":[2],"is":[3,92,143,296],"the":[4,35,140,169,180,213,224,252,284],"simplest":[5],"known":[6],"light":[7,44],"driven":[8],"proton":[9,289],"pump":[10],"and":[11,26,48,111,178,191,217,237,256,269,305],"has":[12],"been":[13,64],"heavily":[14],"studied":[15],"using":[16],"structural":[17,46,73,285],"methods:":[18],"eighty":[19],"four":[20],"X-ray":[21,41,59,117,241],"diffraction,":[22],"six":[23],"electron":[24],"diffraction":[25,118],"three":[27],"NMR":[28],"structures":[29,42,107,131,268],"of":[30,115,154,161,168,172,179,183,254,263,283,287,298,307],"bR":[31,106,130,156,225,292],"are":[32,76,85,272],"deposited":[33,105,116,196,267],"within":[34],"protein":[36],"data":[37,195],"bank.":[38],"Twenty":[39],"one":[40,159],"report":[43],"induced":[45,50,60,242],"changes":[47,49,53,74],"by":[51,81,145,291],"mutation,":[52],"in":[54,94,223],"pH,":[55],"thermal":[56],"annealing":[57],"or":[58],"photo-reduction":[61],"have":[62],"also":[63,245],"examined.":[65],"SCOPE":[66],"OF":[67],"REVIEW:":[68],"We":[69,96],"argue":[70],"that":[71,75,103,209],"light-induced":[72,288],"replicated":[77],"across":[78],"several":[79],"studies":[80,153],"independent":[82],"research":[83],"groups":[84],"those":[86],"most":[87,128],"likely":[88],"to":[89,133,212],"represent":[90],"what":[91],"happening":[93],"reality.":[95],"present":[97],"both":[98],"internal":[99,123],"distance":[100,124],"matrix":[101,125],"analyses":[102],"sort":[104],"into":[108],"hierarchal":[109,163],"trees,":[110],"difference":[112,202,230],"Fourier":[113],"analysis":[114,126,150],"data.":[119],"MAJOR":[120],"CONCLUSIONS:":[121],"An":[122],"separates":[127],"wild-type":[129],"according":[132],"their":[134],"different":[135],"crystal":[136],"forms,":[137],"indicating":[138],"how":[139],"protein's":[141],"structure":[142],"influenced":[144],"crystallization":[146],"conditions.":[147],"A":[148,260],"similar":[149],"clusters":[151],"eleven":[152],"illuminated":[155,198],"crystals":[157,199],"as":[158,274],"branch":[160],"a":[162,205,275,280,299],"tree":[164],"with":[165],"reproducible":[166,234],"movements":[167],"extracellular":[170],"portion":[171,182],"helix":[173,176,184],"C":[174],"towards":[175],"G,":[177],"cytoplasmic":[181],"F":[185],"away":[186],"from":[187],"helices":[188],"A,":[189],"B":[190],"G.":[192],"All":[193],"crystallographic":[194,270],"for":[197],"show":[200],"negative":[201],"density":[203,231],"on":[204],"water":[206,238],"molecule":[207,239],"(Wat402)":[208],"forms":[210],"H-bonds":[211],"retinal":[214],"Schiff":[215],"Base":[216],"two":[218],"aspartate":[219],"residues":[220],"(Asp85,":[221],"Asp212)":[222],"resting":[226],"state.":[227],"Other":[228],"recurring":[229],"features":[232],"indicated":[233],"side-chain,":[235],"backbone":[236],"displacements.":[240],"radiation":[243],"damage":[244],"disorders":[246],"Wat402":[247],"but":[248],"acts":[249],"via":[250],"cleaving":[251],"head-groups":[253],"Asp85":[255],"Asp212.":[257],"GENERAL":[258],"SIGNIFICANCE:":[259],"remarkable":[261],"level":[262],"agreement":[264,279],"exists":[265],"when":[266],"observations":[271],"viewed":[273],"whole.":[276],"From":[277],"this":[278],"unified":[281],"picture":[282],"mechanism":[286],"pumping":[290],"emerges.":[293],"This":[294],"article":[295],"part":[297],"Special":[300],"Issue":[301],"entitled":[302],"Structural":[303],"biochemistry":[304],"biophysics":[306],"membrane":[308],"proteins.":[309]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":12},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
