{"id":"https://openalex.org/W2000268913","doi":"https://doi.org/10.1016/s0361-9230(96)00198-0","title":"Benzodiazepine Receptor Stimulation Blocks Scopolamine-Induced Learning Impairments in a Water Maze Task","display_name":"Benzodiazepine Receptor Stimulation Blocks Scopolamine-Induced Learning Impairments in a Water Maze Task","publication_year":1996,"publication_date":"1996-01-01","ids":{"openalex":"https://openalex.org/W2000268913","doi":"https://doi.org/10.1016/s0361-9230(96)00198-0","mag":"2000268913","pmid":"https://pubmed.ncbi.nlm.nih.gov/8924041"},"language":"en","primary_location":{"id":"doi:10.1016/s0361-9230(96)00198-0","doi":"https://doi.org/10.1016/s0361-9230(96)00198-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0361-9230(96)00198-0","pdf_url":null,"source":{"id":"https://openalex.org/S8119441","display_name":"Brain Research Bulletin","issn_l":"0361-9230","issn":["0361-9230","1873-2747"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research Bulletin","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005933989","display_name":"James W. Smythe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139894009","display_name":"University of Bradford","ror":"https://ror.org/00vs8d940","country_code":"GB","type":"education","lineage":["https://openalex.org/I139894009"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"JAMES W SMYTHE","raw_affiliation_strings":["Department of Pharmacology, University of Bradford, West Yorkshire, UK","Postgraduate Studies in Neuropharmacology, Department of Pharmacology, University of Bradford, Bradford, West Yorkshire BD7 1DP, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Bradford, West Yorkshire, UK","institution_ids":["https://openalex.org/I139894009"]},{"raw_affiliation_string":"Postgraduate Studies in Neuropharmacology, Department of Pharmacology, University of Bradford, Bradford, West Yorkshire BD7 1DP, UK","institution_ids":["https://openalex.org/I139894009"]}]},{"author_position":"middle","author":{"id":null,"display_name":"DEBORAH MURPHY","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139894009","display_name":"University of Bradford","ror":"https://ror.org/00vs8d940","country_code":"GB","type":"education","lineage":["https://openalex.org/I139894009"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"DEBORAH MURPHY","raw_affiliation_strings":["Postgraduate Studies in Neuropharmacology, Department of Pharmacology, University of Bradford, Bradford, West Yorkshire BD7 1DP, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Postgraduate Studies in Neuropharmacology, Department of Pharmacology, University of Bradford, Bradford, West Yorkshire BD7 1DP, UK","institution_ids":["https://openalex.org/I139894009"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060211915","display_name":"B. Costall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139894009","display_name":"University of Bradford","ror":"https://ror.org/00vs8d940","country_code":"GB","type":"education","lineage":["https://openalex.org/I139894009"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"BRENDA COSTALL","raw_affiliation_strings":["Postgraduate Studies in Neuropharmacology, Department of Pharmacology, University of Bradford, Bradford, West Yorkshire BD7 1DP, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Postgraduate Studies in Neuropharmacology, Department of Pharmacology, University of Bradford, Bradford, West Yorkshire BD7 1DP, UK","institution_ids":["https://openalex.org/I139894009"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5005933989"],"corresponding_institution_ids":["https://openalex.org/I139894009"],"apc_list":{"value":3280,"currency":"USD","value_usd":3280},"apc_paid":null,"fwci":0.6898,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.67239274,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":"5","first_page":"299","last_page":"304"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.8701000213623047,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.8701000213623047,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.03579999879002571,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.030799999833106995,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diazepam","display_name":"diazepam","score":0.9490000009536743},{"id":"https://openalex.org/keywords/scopolamine","display_name":"scopolamine","score":0.9950000047683716},{"id":"https://openalex.org/keywords/cholinergic-blockade","display_name":"cholinergic blockade","score":0.8149999976158142},{"id":"https://openalex.org/keywords/learning-disabilities","display_name":"learning disabilities","score":0.8180000185966492},{"id":"https://openalex.org/keywords/anxiety-like-behavior","display_name":"anxiety-like behavior","score":0.8109999895095825},{"id":"https://openalex.org/keywords/water-maze","display_name":"water maze","score":0.7099999785423279},{"id":"https://openalex.org/keywords/memory-consolidation","display_name":"memory consolidation","score":0.6899999976158142},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.503000020980835}],"concepts":[{"id":"https://openalex.org/C2776175493","wikidata":"https://www.wikidata.org/wiki/Q210402","display_name":"Diazepam","level":2,"score":0.74583500623703},{"id":"https://openalex.org/C2778173252","wikidata":"https://www.wikidata.org/wiki/Q83871","display_name":"Benzodiazepine","level":3,"score":0.7293641567230225},{"id":"https://openalex.org/C22885893","wikidata":"https://www.wikidata.org/wiki/Q4862743","display_name":"Cholinergic","level":2,"score":0.6904911994934082},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6321954727172852},{"id":"https://openalex.org/C2777765862","wikidata":"https://www.wikidata.org/wiki/Q62903","display_name":"Anxiolytic","level":3,"score":0.6124552488327026},{"id":"https://openalex.org/C173586616","wikidata":"https://www.wikidata.org/wiki/Q5359685","display_name":"Elevated plus maze","level":3,"score":0.5929221510887146},{"id":"https://openalex.org/C2780352252","wikidata":"https://www.wikidata.org/wiki/Q422543","display_name":"Corticosterone","level":3,"score":0.5843677520751953},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5755907893180847},{"id":"https://openalex.org/C12515866","wikidata":"https://www.wikidata.org/wiki/Q50628021","display_name":"Water maze","level":3,"score":0.5515416264533997},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.45759090781211853},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.45234668254852295},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.4242897033691406},{"id":"https://openalex.org/C44752575","wikidata":"https://www.wikidata.org/wiki/Q1417562","display_name":"Morris water navigation task","level":3,"score":0.4215976595878601},{"id":"https://openalex.org/C2778468042","wikidata":"https://www.wikidata.org/wiki/Q273976","display_name":"Blockade","level":3,"score":0.41885846853256226},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4069826006889343},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.37299221754074097},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36307597160339355},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.31307512521743774},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2438214123249054},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.11639836430549622},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.08524703979492188},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.07852175831794739}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003975","descriptor_name":"Diazepam","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008568","descriptor_name":"Memory","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012601","descriptor_name":"Scopolamine","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D012601","descriptor_name":"Scopolamine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018727","descriptor_name":"Muscarinic Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D018757","descriptor_name":"GABA Modulators","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018782","descriptor_name":"Maze Learning","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058785","descriptor_name":"GABA-A Receptor Agonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0361-9230(96)00198-0","doi":"https://doi.org/10.1016/s0361-9230(96)00198-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0361-9230(96)00198-0","pdf_url":null,"source":{"id":"https://openalex.org/S8119441","display_name":"Brain Research Bulletin","issn_l":"0361-9230","issn":["0361-9230","1873-2747"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research Bulletin","raw_type":"journal-article"},{"id":"pmid:8924041","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8924041","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain research bulletin","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1540136915","https://openalex.org/W1595894560","https://openalex.org/W1964189385","https://openalex.org/W1977025722","https://openalex.org/W1986186530","https://openalex.org/W1986199494","https://openalex.org/W1992975043","https://openalex.org/W1993109188","https://openalex.org/W1998532707","https://openalex.org/W2018663000","https://openalex.org/W2027009747","https://openalex.org/W2027066860","https://openalex.org/W2029904551","https://openalex.org/W2030346523","https://openalex.org/W2036818530","https://openalex.org/W2042349780","https://openalex.org/W2045861226","https://openalex.org/W2046408068","https://openalex.org/W2050045237","https://openalex.org/W2052361796","https://openalex.org/W2054993348","https://openalex.org/W2062706679","https://openalex.org/W2074802748","https://openalex.org/W2090424711","https://openalex.org/W2110467271","https://openalex.org/W2114608871","https://openalex.org/W2145864819","https://openalex.org/W2499580087"],"related_works":["https://openalex.org/W2091600056","https://openalex.org/W7015589976","https://openalex.org/W2057939619","https://openalex.org/W2171822979","https://openalex.org/W2052165173","https://openalex.org/W2079736440","https://openalex.org/W2027691082","https://openalex.org/W1838847117","https://openalex.org/W2089170472","https://openalex.org/W1996372262"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}