{"id":"https://openalex.org/W2000261098","doi":"https://doi.org/10.1136/thx.48.10.996","title":"Histologically atypical Pneumocystis carinii pneumonia.","display_name":"Histologically atypical Pneumocystis carinii pneumonia.","publication_year":1993,"publication_date":"1993-10-01","ids":{"openalex":"https://openalex.org/W2000261098","doi":"https://doi.org/10.1136/thx.48.10.996","mag":"2000261098","pmid":"https://pubmed.ncbi.nlm.nih.gov/8256247","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/464808"},"language":"en","primary_location":{"id":"doi:10.1136/thx.48.10.996","doi":"https://doi.org/10.1136/thx.48.10.996","is_oa":true,"landing_page_url":"https://doi.org/10.1136/thx.48.10.996","pdf_url":"https://thorax.bmj.com/content/thoraxjnl/48/10/996.full.pdf","source":{"id":"https://openalex.org/S106546978","display_name":"Thorax","issn_l":"0040-6376","issn":["0040-6376","1468-3296"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thorax","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://thorax.bmj.com/content/thoraxjnl/48/10/996.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019577773","display_name":"N M Foley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"N M Foley","raw_affiliation_strings":["Department of Medicine, University College London Medical School, Middlesex Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University College London Medical School, Middlesex Hospital","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110691845","display_name":"Meryl H.G. Griffiths","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M H Griffiths","raw_affiliation_strings":["Department of Medicine, University College London Medical School, Middlesex Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University College London Medical School, Middlesex Hospital","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102906879","display_name":"Robert F. Miller","orcid":"https://orcid.org/0000-0003-2067-4291","observed_orcids":["https://orcid.org/0000-0003-2067-4291"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R F Miller","raw_affiliation_strings":["Department of Medicine, University College London Medical School, Middlesex Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University College London Medical School, Middlesex Hospital","institution_ids":["https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I45129253"],"apc_list":null,"apc_paid":null,"fwci":1.7758,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.83132643,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"48","issue":"10","first_page":"996","last_page":"1001"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12369","display_name":"Pneumocystis jirovecii pneumonia detection and treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12369","display_name":"Pneumocystis jirovecii pneumonia detection and treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10654","display_name":"Pneumonia and Respiratory Infections","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pneumocystis-jirovecii-pneumonia","display_name":"Pneumocystis carinii pneumonia","score":0.972000002861023},{"id":"https://openalex.org/keywords/atypical-histology","display_name":"atypical histology","score":0.7940000295639038},{"id":"https://openalex.org/keywords/granulomatous-pneumonia","display_name":"granulomatous pneumonia","score":0.9169999957084656},{"id":"https://openalex.org/keywords/diffuse-alveolar-damage","display_name":"diffuse alveolar damage","score":0.9959999918937683},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.5740000009536743},{"id":"https://openalex.org/keywords/lung-biopsy","display_name":"lung biopsy","score":0.9160000085830688},{"id":"https://openalex.org/keywords/bronchoalveolar-lavage","display_name":"bronchoalveolar lavage","score":0.8740000128746033},{"id":"https://openalex.org/keywords/cytomegalovirus-infection","display_name":"cytomegalovirus infection","score":0.828000009059906}],"concepts":[{"id":"https://openalex.org/C2993443204","wikidata":"https://www.wikidata.org/wiki/Q134478","display_name":"Pneumocystis carinii","level":4,"score":0.9634343385696411},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8958995342254639},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.7591394186019897},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4232676029205322},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3392578959465027},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11711400747299194},{"id":"https://openalex.org/C2777559004","wikidata":"https://www.wikidata.org/wiki/Q134478","display_name":"Pneumocystis jirovecii","level":3,"score":0.09816768765449524}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011020","descriptor_name":"Pneumonia, Pneumocystis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011020","descriptor_name":"Pneumonia, Pneumocystis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017088","descriptor_name":"AIDS-Related Opportunistic Infections","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D017088","descriptor_name":"AIDS-Related Opportunistic Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1136/thx.48.10.996","doi":"https://doi.org/10.1136/thx.48.10.996","is_oa":true,"landing_page_url":"https://doi.org/10.1136/thx.48.10.996","pdf_url":"https://thorax.bmj.com/content/thoraxjnl/48/10/996.full.pdf","source":{"id":"https://openalex.org/S106546978","display_name":"Thorax","issn_l":"0040-6376","issn":["0040-6376","1468-3296"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thorax","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:464808","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/464808","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thorax","raw_type":"Text"},{"id":"pmid:8256247","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8256247","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thorax","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1385669","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1385669/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Thorax , 48 (10) pp. 996-1001. (1993)","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1136/thx.48.10.996","doi":"https://doi.org/10.1136/thx.48.10.996","is_oa":true,"landing_page_url":"https://doi.org/10.1136/thx.48.10.996","pdf_url":"https://thorax.bmj.com/content/thoraxjnl/48/10/996.full.pdf","source":{"id":"https://openalex.org/S106546978","display_name":"Thorax","issn_l":"0040-6376","issn":["0040-6376","1468-3296"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thorax","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2000261098.pdf","grobid_xml":"https://content.openalex.org/works/W2000261098.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W146136322","https://openalex.org/W1965057707","https://openalex.org/W1974991644","https://openalex.org/W1981853937","https://openalex.org/W2007049448","https://openalex.org/W2008781514","https://openalex.org/W2009371816","https://openalex.org/W2013919336","https://openalex.org/W2014974787","https://openalex.org/W2016029962","https://openalex.org/W2023787064","https://openalex.org/W2024460979","https://openalex.org/W2033321018","https://openalex.org/W2046897313","https://openalex.org/W2048882550","https://openalex.org/W2064221694","https://openalex.org/W2100665411","https://openalex.org/W2107707269","https://openalex.org/W2117863964","https://openalex.org/W2119042541","https://openalex.org/W2147148358","https://openalex.org/W2411607888","https://openalex.org/W2461742703","https://openalex.org/W2915731487"],"related_works":["https://openalex.org/W2066451952","https://openalex.org/W2023787064","https://openalex.org/W2320124079","https://openalex.org/W2411067076","https://openalex.org/W2409781749","https://openalex.org/W2018102360","https://openalex.org/W2084806029","https://openalex.org/W2377080979","https://openalex.org/W1970174616","https://openalex.org/W2231545526"],"abstract_inverted_index":{"BACKGROUND:":[0],"Infection":[1],"with":[2,23],"Pneumocystis":[3],"carinii":[4,37,221],"typically":[5],"results":[6,68],"in":[7,97,135,139,146,153,157,168,177,188,199,230],"a":[8,24,51,98,107],"pneumonia":[9,53,94,167],"which":[10,124],"histologically":[11,91],"is":[12,214],"seen":[13,198],"to":[14],"consist":[15],"of":[16,35,69,88,90,100,116,219,227],"an":[17],"eosinophilic":[18],"foamy":[19],"alveolar":[20,41,56,172],"exudate":[21],"associated":[22],"mild":[25],"plasma":[26],"cell":[27],"interstitial":[28],"infiltrate.":[29],"Special":[30],"stains":[31],"show":[32],"that":[33],"cysts":[34,176],"P":[36,220],"lie":[38],"within":[39],"the":[40,61],"exudate.":[42],"Atypical":[43,148],"histological":[44,81,122,194],"appearances":[45,123,149,195],"may":[46,64,196],"occasionally":[47],"be":[48,65,197,209,223],"seen,":[49],"including":[50],"granulomatous":[52,151],"and":[54,67,77,86,141,174,185,217],"diffuse":[55,171],"damage.":[57],"In":[58],"these":[59],"patients":[60,112],"clinical":[62],"presentation":[63,89],"atypical":[66,92,121,193],"investigations":[70],"negative":[71,128,216],"unless":[72],"lung":[73,133,232],"biopsies":[74],"are":[75],"performed":[76],"tissue":[78],"obtained":[79],"for":[80],"examination.":[82],"METHODS:":[83],"The":[84],"incidence":[85],"mode":[87],"pneumocystis":[93,114,200],"was":[95],"studied":[96],"cohort":[99],"HIV-I":[101,236],"antibody":[102,237],"positive":[103,238],"patients.":[104,190,239],"RESULTS:":[105],"Over":[106],"30":[108],"month":[109],"period":[110],"138":[111],"had":[113,120,161,181],"pneumonia,":[115],"whom":[117],"eight":[118],"(6%)":[119],"were":[125],"diagnosed":[126],"(after":[127],"bronchoalveolar":[129,212],"lavage)":[130],"by":[131,225],"open":[132],"biopsy":[134,138,203,233],"five,":[136],"percutaneous":[137,205],"one,":[140],"at":[142],"post":[143],"mortem":[144],"examination":[145],"two.":[147],"included":[150],"inflammation":[152],"four":[154],"patients,":[155],"\"pneumocystoma\"":[156],"two":[158,189],"(one":[159],"also":[160,180],"extrapulmonary":[162,186],"pneumocystosis),":[163],"bronchiolitis":[164],"obliterans":[165],"organising":[166],"one":[169,178],"patient,":[170],"damage":[173],"subpleural":[175],"(who":[179],"intrapulmonary":[182],"cytomegalovirus":[183],"infection),":[184],"pneumocystosis":[187],"CONCLUSIONS:":[191],"Various":[192],"pneumonia.":[201],"Lung":[202],"(either":[204],"or":[206],"open)":[207],"should":[208,222],"considered":[210],"when":[211],"lavage":[213],"repeatedly":[215],"evidence":[218],"sought,":[224],"use":[226],"special":[228],"stains,":[229],"all":[231],"material":[234],"from":[235]},"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}