{"id":"https://openalex.org/W2000242561","doi":"https://doi.org/10.1016/s0896-6273(01)80052-0","title":"Synaptotagmin\u2013Syntaxin Interaction: The C2 Domain as a Ca2+-Dependent Electrostatic Switch","display_name":"Synaptotagmin\u2013Syntaxin Interaction: The C2 Domain as a Ca2+-Dependent Electrostatic Switch","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W2000242561","doi":"https://doi.org/10.1016/s0896-6273(01)80052-0","mag":"2000242561","pmid":"https://pubmed.ncbi.nlm.nih.gov/9010211"},"language":"en","primary_location":{"id":"doi:10.1016/s0896-6273(01)80052-0","doi":"https://doi.org/10.1016/s0896-6273(01)80052-0","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0896-6273(01)80052-0","pdf_url":"http://www.cell.com/article/S0896627301800520/pdf","source":{"id":"https://openalex.org/S45757444","display_name":"Neuron","issn_l":"0896-6273","issn":["0896-6273","1097-4199"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuron","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2000242561"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0896627301800520/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111913559","display_name":"Xuguang Shao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xuguang Shao","raw_affiliation_strings":["Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas 75235, USA","Departments of Biochemistry and Pharmacology, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas 75235, USA","institution_ids":["https://openalex.org/I867280407"]},{"raw_affiliation_string":"Departments of Biochemistry and Pharmacology, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Cai Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cai Li","raw_affiliation_strings":["Department of Molecular Genetics, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Genetics, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103430979","display_name":"Imma Fern\u00e1ndez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Imma Fernandez","raw_affiliation_strings":["Departments of Biochemistry and Pharmacology, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biochemistry and Pharmacology, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108047369","display_name":"Xiangyang Zhang","orcid":"https://orcid.org/0000-0001-9137-2085","observed_orcids":["https://orcid.org/0000-0001-9137-2085"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiangyang Zhang","raw_affiliation_strings":["Department of Molecular Genetics, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Genetics, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111931611","display_name":"Thomas Christian S\u00fcdhof","orcid":"https://orcid.org/0000-0003-3361-9275","observed_orcids":["https://orcid.org/0000-0003-3361-9275"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas C. S\u00fcdhof","raw_affiliation_strings":["Department of Molecular Genetics, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Genetics, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I867280407"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065106268","display_name":"Josep Rizo","orcid":"https://orcid.org/0000-0003-1773-8311","observed_orcids":["https://orcid.org/0000-0003-1773-8311"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Josep Rizo","raw_affiliation_strings":["Departments of Biochemistry and Pharmacology, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biochemistry and Pharmacology, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I867280407"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5065106268"],"corresponding_institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I867280407"],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":null,"fwci":5.0229,"has_fulltext":false,"cited_by_count":245,"citation_normalized_percentile":{"value":0.96636313,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"18","issue":"1","first_page":"133","last_page":"142"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/synaptotagmin-1","display_name":"synaptotagmin-1","score":0.996999979019165},{"id":"https://openalex.org/keywords/syntaxin","display_name":"syntaxin","score":0.9869999885559082},{"id":"https://openalex.org/keywords/c2-domain","display_name":"C2 domain","score":0.8939999938011169},{"id":"https://openalex.org/keywords/c2a-domain","display_name":"C2A domain","score":0.9509999752044678},{"id":"https://openalex.org/keywords/calcium-binding","display_name":"calcium binding","score":0.6179999709129333},{"id":"https://openalex.org/keywords/electrostatic-switch","display_name":"electrostatic switch","score":0.628000020980835},{"id":"https://openalex.org/keywords/synaptic-vesicle-exocytosis","display_name":"synaptic vesicle exocytosis","score":0.8989999890327454},{"id":"https://openalex.org/keywords/neurotransmitter-release","display_name":"neurotransmitter release","score":0.9309999942779541},{"id":"https://openalex.org/keywords/membrane-fusion","display_name":"membrane fusion","score":0.7179999947547913},{"id":"https://openalex.org/keywords/calcium-indicator","display_name":"calcium sensor","score":0.6639999747276306},{"id":"https://openalex.org/keywords/basic-residues","display_name":"basic residues","score":0.5320000052452087},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.6690000295639038}],"concepts":[{"id":"https://openalex.org/C86473631","wikidata":"https://www.wikidata.org/wiki/Q18031809","display_name":"Synaptotagmin 1","level":5,"score":0.9681849479675293},{"id":"https://openalex.org/C2909695770","wikidata":"https://www.wikidata.org/wiki/Q426764","display_name":"Synaptotagmin I","level":5,"score":0.8280327320098877},{"id":"https://openalex.org/C53728453","wikidata":"https://www.wikidata.org/wiki/Q18031771","display_name":"STX1A","level":5,"score":0.8217260837554932},{"id":"https://openalex.org/C2778256703","wikidata":"https://www.wikidata.org/wiki/Q390407","display_name":"Syntaxin","level":4,"score":0.6972113847732544},{"id":"https://openalex.org/C196330066","wikidata":"https://www.wikidata.org/wiki/Q7923216","display_name":"Vesicle fusion","level":5,"score":0.6695515513420105},{"id":"https://openalex.org/C143840085","wikidata":"https://www.wikidata.org/wiki/Q5008102","display_name":"C2 domain","level":3,"score":0.6596807241439819},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6077993512153625},{"id":"https://openalex.org/C148785051","wikidata":"https://www.wikidata.org/wiki/Q671136","display_name":"Synaptic vesicle","level":4,"score":0.5466998815536499},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5335406064987183},{"id":"https://openalex.org/C175969161","wikidata":"https://www.wikidata.org/wiki/Q323426","display_name":"Exocytosis","level":3,"score":0.5154901146888733},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.47813475131988525},{"id":"https://openalex.org/C103038307","wikidata":"https://www.wikidata.org/wiki/Q6556360","display_name":"Lipid bilayer fusion","level":3,"score":0.4522949457168579},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.3084273934364319},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28706154227256775},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2429557740688324},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.16694140434265137}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002135","descriptor_name":"Calcium-Binding Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002942","descriptor_name":"Circular Dichroism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005982","descriptor_name":"Glutathione Transferase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008561","descriptor_name":"Membrane Fusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011489","descriptor_name":"Protein Denaturation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016297","descriptor_name":"Mutagenesis, Site-Directed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017354","descriptor_name":"Point Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050765","descriptor_name":"Qa-SNARE Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050857","descriptor_name":"Synaptotagmins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050863","descriptor_name":"Synaptotagmin I","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055672","descriptor_name":"Static Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0896-6273(01)80052-0","doi":"https://doi.org/10.1016/s0896-6273(01)80052-0","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0896-6273(01)80052-0","pdf_url":"http://www.cell.com/article/S0896627301800520/pdf","source":{"id":"https://openalex.org/S45757444","display_name":"Neuron","issn_l":"0896-6273","issn":["0896-6273","1097-4199"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuron","raw_type":"journal-article"},{"id":"pmid:9010211","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9010211","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuron","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0896-6273(01)80052-0","doi":"https://doi.org/10.1016/s0896-6273(01)80052-0","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0896-6273(01)80052-0","pdf_url":"http://www.cell.com/article/S0896627301800520/pdf","source":{"id":"https://openalex.org/S45757444","display_name":"Neuron","issn_l":"0896-6273","issn":["0896-6273","1097-4199"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuron","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G229552668","display_name":null,"funder_award_id":"R01-MH52804-01","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G3004503974","display_name":"STRUCTURAL AND BINDING PROPERTIES OF SYNAPTOTAGMIN","funder_award_id":"R29NS033731","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G4404769415","display_name":null,"funder_award_id":"R29 NS33731-01A1","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G5251133680","display_name":"Function of Neurexins","funder_award_id":"R01MH052804","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320306080","display_name":"Foundation for the National Institutes of Health","ror":"https://ror.org/00k86s890"},{"id":"https://openalex.org/F4320306196","display_name":"Welch Foundation","ror":"https://ror.org/00np6vq88"},{"id":"https://openalex.org/F4320306199","display_name":"Hearst Foundations","ror":"https://ror.org/03s96de24"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2000242561.pdf"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W7725224","https://openalex.org/W1481032119","https://openalex.org/W1490238549","https://openalex.org/W1525752116","https://openalex.org/W1529696685","https://openalex.org/W1555714096","https://openalex.org/W1591133722","https://openalex.org/W1603561844","https://openalex.org/W1869532508","https://openalex.org/W1967817609","https://openalex.org/W1976283234","https://openalex.org/W1984953308","https://openalex.org/W1990220309","https://openalex.org/W1998944135","https://openalex.org/W1999127249","https://openalex.org/W2014181207","https://openalex.org/W2018757497","https://openalex.org/W2021788635","https://openalex.org/W2029160544","https://openalex.org/W2030433731","https://openalex.org/W2030987020","https://openalex.org/W2031481730","https://openalex.org/W2042055643","https://openalex.org/W2044162798","https://openalex.org/W2051958752","https://openalex.org/W2054643844","https://openalex.org/W2056293200","https://openalex.org/W2061083495","https://openalex.org/W2068446924","https://openalex.org/W2069734146","https://openalex.org/W2078039225","https://openalex.org/W2080354575","https://openalex.org/W2084266280","https://openalex.org/W2085680244","https://openalex.org/W2086036400","https://openalex.org/W2089827948","https://openalex.org/W2093687422","https://openalex.org/W2094411368","https://openalex.org/W2106315897","https://openalex.org/W2114640601","https://openalex.org/W2165302477","https://openalex.org/W2179964627"],"related_works":["https://openalex.org/W1981385619","https://openalex.org/W2105305770","https://openalex.org/W1970930136","https://openalex.org/W3004596066","https://openalex.org/W2021285837","https://openalex.org/W2042494277","https://openalex.org/W1975830464","https://openalex.org/W2056850818","https://openalex.org/W2022292190","https://openalex.org/W1994827487"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}