{"id":"https://openalex.org/W2000236517","doi":"https://doi.org/10.1083/jcb.100.6.1848","title":"Binding of laminin to type IV collagen: a morphological study.","display_name":"Binding of laminin to type IV collagen: a morphological study.","publication_year":1985,"publication_date":"1985-06-01","ids":{"openalex":"https://openalex.org/W2000236517","doi":"https://doi.org/10.1083/jcb.100.6.1848","mag":"2000236517","pmid":"https://pubmed.ncbi.nlm.nih.gov/3997977","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2113590"},"language":"en","primary_location":{"id":"doi:10.1083/jcb.100.6.1848","doi":"https://doi.org/10.1083/jcb.100.6.1848","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.100.6.1848","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2000236517"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2113590/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083210618","display_name":"ARISTIDIS S. CHARONIS","orcid":"https://orcid.org/0000-0001-9956-732X","observed_orcids":["https://orcid.org/0000-0001-9956-732X"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A S Charonis","raw_affiliation_strings":["Yale University  ;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yale University  ;","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112182524","display_name":"Effie C. Tsilibary","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E C Tsilibary","raw_affiliation_strings":["Yale University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yale University","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007016006","display_name":"Peter D. Yurchenco","orcid":"https://orcid.org/0000-0003-0387-2317","observed_orcids":["https://orcid.org/0000-0003-0387-2317"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P D Yurchenco","raw_affiliation_strings":["Robert Wood Johnson Medical School (RWJMS), Pathology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robert Wood Johnson Medical School (RWJMS), Pathology","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027220020","display_name":"Heinz Furthmayr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H Furthmayr","raw_affiliation_strings":["Yale University  ;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yale University  ;","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":10.0845,"has_fulltext":true,"cited_by_count":202,"citation_normalized_percentile":{"value":0.981026,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"100","issue":"6","first_page":"1848","last_page":"1853"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.8769999742507935,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.8769999742507935,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.03319999948143959,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.026599999517202377,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/laminin","display_name":"laminin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/type-iv-collagen","display_name":"type IV collagen","score":1.0},{"id":"https://openalex.org/keywords/noncollagenous-domain","display_name":"noncollagenous domain","score":0.6620000004768372},{"id":"https://openalex.org/keywords/pepsin-treatment","display_name":"pepsin treatment","score":0.7120000123977661},{"id":"https://openalex.org/keywords/thermal-denaturation","display_name":"thermal denaturation","score":0.8569999933242798},{"id":"https://openalex.org/keywords/basement-membrane","display_name":"basement membrane","score":0.5989999771118164},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.6759999990463257}],"concepts":[{"id":"https://openalex.org/C2779814568","wikidata":"https://www.wikidata.org/wiki/Q58345","display_name":"Laminin","level":3,"score":0.9339157342910767},{"id":"https://openalex.org/C2777107211","wikidata":"https://www.wikidata.org/wiki/Q7860610","display_name":"Type IV collagen","level":4,"score":0.674436092376709},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4750385582447052},{"id":"https://openalex.org/C38008103","wikidata":"https://www.wikidata.org/wiki/Q5145884","display_name":"Collagen, type I, alpha 1","level":3,"score":0.46606117486953735},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4234086871147156},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.37845706939697266},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.356749951839447}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002244","descriptor_name":"Carbon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007797","descriptor_name":"Laminin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010984","descriptor_name":"Platinum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011489","descriptor_name":"Protein Denaturation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046911","descriptor_name":"Macromolecular Substances","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1083/jcb.100.6.1848","doi":"https://doi.org/10.1083/jcb.100.6.1848","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.100.6.1848","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2113590","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2113590/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2113590/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},{"id":"pmid:3997977","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3997977","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.277.7539","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.277.7539","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/4f/ce/J_Cell_Biol_1985_Jun_1_100(6)_1848-1853.tar.gz","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2113590","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2113590/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2113590/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G6646080440","display_name":"STRUCTURAL COMPOSITION OF BASEMENT MEMBRANES","funder_award_id":"5r01am030556-04","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000335157","display_name":null,"funder_award_id":"GM-07562","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2000236517.pdf","grobid_xml":"https://content.openalex.org/works/W2000236517.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W88723889","https://openalex.org/W1484745378","https://openalex.org/W1492741817","https://openalex.org/W1628719417","https://openalex.org/W1775749144","https://openalex.org/W1981056738","https://openalex.org/W1988447189","https://openalex.org/W1989384629","https://openalex.org/W1993352932","https://openalex.org/W1995797967","https://openalex.org/W2006140887","https://openalex.org/W2015648732","https://openalex.org/W2026568703","https://openalex.org/W2034244905","https://openalex.org/W2040832260","https://openalex.org/W2056046445","https://openalex.org/W2064023016","https://openalex.org/W2088074670","https://openalex.org/W2113127961","https://openalex.org/W2157145995","https://openalex.org/W2399125310"],"related_works":["https://openalex.org/W2017224145","https://openalex.org/W2084258562","https://openalex.org/W2055018696","https://openalex.org/W2431237659","https://openalex.org/W2013851855","https://openalex.org/W2169179862","https://openalex.org/W1998467991","https://openalex.org/W2040294140","https://openalex.org/W2124389355"],"abstract_inverted_index":{"A":[0],"mixture":[1],"of":[2,31,56,86,103,105,118,142],"laminin":[3,93,119,143],"and":[4,15,43,125],"type":[5,26,57,69,96,131],"IV":[6,27,58,70,89,97,132],"collagen":[7,59,98,133],"was":[8,19],"analyzed":[9],"by":[10,113],"rotary":[11],"shadowing":[12],"using":[13,115],"carbon/platinum":[14],"electron":[16],"microscopy.":[17],"Laminin":[18],"found":[20],"to":[21,63,80,95,130],"form":[22,81],"distinct":[23],"complexes":[24,82,90],"with":[25,65,83],"collagen:":[28],"one":[29],"site":[30],"interaction":[32],"is":[33,46,111,147],"located":[34,47],"140":[35],"nm":[36],"from":[37],"the":[38,44,49,74,87,100,122],"COOH-terminal,":[39],"noncollagenous":[40],"(NC1)":[41],"domain":[42],"other":[45],"within":[48],"NH2-terminal":[50],"region.":[51],"The":[52],"isolated":[53],"NC1":[54,75],"fragment":[55,116],"does":[60,127],"not":[61,128],"appear":[62],"interact":[64],"laminin,":[66],"while":[67],"pepsin-treated":[68],"collagen,":[71],"which":[72,120,126],"lacks":[73,121],"domain,":[76],"retains":[77],"its":[78,106],"ability":[79],"laminin.":[84],"Analysis":[85],"laminin-type":[88],"indicates":[91],"that":[92],"binds":[94],"via":[99],"globular":[101,123],"regions":[102,124],"either":[104],"four":[107],"arms.":[108],"This":[109],"finding":[110],"supported":[112],"experiments":[114],"P1":[117],"bind":[129],"in":[134],"a":[135],"specific":[136,145],"way.":[137],"In":[138],"addition,":[139],"after":[140],"heat-denaturation":[141],"no":[144],"binding":[146],"observed.":[148]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}