{"id":"https://openalex.org/W2000232525","doi":"https://doi.org/10.1111/j.1462-5822.2005.00607.x","title":"Specific host genes required for the killing of Klebsiella bacteria by phagocytes","display_name":"Specific host genes required for the killing of Klebsiella bacteria by phagocytes","publication_year":2005,"publication_date":"2005-10-18","ids":{"openalex":"https://openalex.org/W2000232525","doi":"https://doi.org/10.1111/j.1462-5822.2005.00607.x","mag":"2000232525","pmid":"https://pubmed.ncbi.nlm.nih.gov/16367873"},"language":"en","primary_location":{"id":"doi:10.1111/j.1462-5822.2005.00607.x","doi":"https://doi.org/10.1111/j.1462-5822.2005.00607.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1462-5822.2005.00607.x","pdf_url":null,"source":{"id":"https://openalex.org/S113048938","display_name":"Cellular Microbiology","issn_l":"1462-5814","issn":["1462-5814","1462-5822"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://archive-ouverte.unige.ch/unige:39521","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060891801","display_name":"Mohammed Benghezal","orcid":"https://orcid.org/0000-0002-4207-0192","observed_orcids":["https://orcid.org/0000-0002-4207-0192"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohammed Benghezal","raw_affiliation_strings":["Athelas SA, Chemin des Aulx 18, 1228 Plan-les-Ouates, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Athelas SA, Chemin des Aulx 18, 1228 Plan-les-Ouates, Geneva, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023545229","display_name":"Marie\u2010Odile Fauvarque","orcid":"https://orcid.org/0000-0001-5020-3701","observed_orcids":["https://orcid.org/0000-0001-5020-3701"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I177483745","display_name":"Universit\u00e9 Joseph Fourier","ror":"https://ror.org/02aj0kh94","country_code":"FR","type":"education","lineage":["https://openalex.org/I177483745","https://openalex.org/I899635006"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I3020098449","display_name":"CEA Grenoble","ror":"https://ror.org/02mg6n827","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I3020098449"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie-Odile Fauvarque","raw_affiliation_strings":["Laboratoire de Biochimie et Biophysique des Syst\u00e8mes Int\u00e9gr\u00e9s, UMR5092, CEA/CNRS/UJF, 17 rue des Martyrs, 38054 Grenoble, Cedex 9, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biochimie et Biophysique des Syst\u00e8mes Int\u00e9gr\u00e9s, UMR5092, CEA/CNRS/UJF, 17 rue des Martyrs, 38054 Grenoble, Cedex 9, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I177483745","https://openalex.org/I2738703131","https://openalex.org/I3020098449"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017391416","display_name":"R\u00e9gis Tournebize","orcid":"https://orcid.org/0000-0003-3718-3130","observed_orcids":["https://orcid.org/0000-0003-3718-3130"]},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Regis Tournebize","raw_affiliation_strings":["Institut Pasteur, Pathog\u00e9nie Microbienne Mol\u00e9culaire, 28, rue du Dr. Roux, 75724 Paris, Cedex 15, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Pathog\u00e9nie Microbienne Mol\u00e9culaire, 28, rue du Dr. Roux, 75724 Paris, Cedex 15, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068548277","display_name":"Romain Froquet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114457229","display_name":"University of Geneva","ror":"https://ror.org/01swzsf04","country_code":"CH","type":"education","lineage":["https://openalex.org/I114457229"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Romain Froquet","raw_affiliation_strings":["Universit\u00e9 de Gen\u00e8ve, Centre M\u00e9dical Universitaire, D\u00e9partement de Physiologie Cellulaire et M\u00e9tabolisme, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Gen\u00e8ve, Centre M\u00e9dical Universitaire, D\u00e9partement de Physiologie Cellulaire et M\u00e9tabolisme, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland","institution_ids":["https://openalex.org/I114457229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065176732","display_name":"Anna Marchetti","orcid":"https://orcid.org/0009-0003-8737-7280","observed_orcids":["https://orcid.org/0009-0003-8737-7280"]},"institutions":[{"id":"https://openalex.org/I114457229","display_name":"University of Geneva","ror":"https://ror.org/01swzsf04","country_code":"CH","type":"education","lineage":["https://openalex.org/I114457229"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Anna Marchetti","raw_affiliation_strings":["Universit\u00e9 de Gen\u00e8ve, Centre M\u00e9dical Universitaire, D\u00e9partement de Physiologie Cellulaire et M\u00e9tabolisme, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Gen\u00e8ve, Centre M\u00e9dical Universitaire, D\u00e9partement de Physiologie Cellulaire et M\u00e9tabolisme, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland","institution_ids":["https://openalex.org/I114457229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040861877","display_name":"Evelyne Bergeret","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I177483745","display_name":"Universit\u00e9 Joseph Fourier","ror":"https://ror.org/02aj0kh94","country_code":"FR","type":"education","lineage":["https://openalex.org/I177483745","https://openalex.org/I899635006"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I3020098449","display_name":"CEA Grenoble","ror":"https://ror.org/02mg6n827","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I3020098449"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Evelyne Bergeret","raw_affiliation_strings":["Laboratoire de Biochimie et Biophysique des Syst\u00e8mes Int\u00e9gr\u00e9s, UMR5092, CEA/CNRS/UJF, 17 rue des Martyrs, 38054 Grenoble, Cedex 9, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biochimie et Biophysique des Syst\u00e8mes Int\u00e9gr\u00e9s, UMR5092, CEA/CNRS/UJF, 17 rue des Martyrs, 38054 Grenoble, Cedex 9, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I177483745","https://openalex.org/I2738703131","https://openalex.org/I3020098449"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070124102","display_name":"Bernard Lardy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800555055","display_name":"Centre Hospitalier Universitaire de Grenoble","ror":"https://ror.org/041rhpw39","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I2800555055"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bernard Lardy","raw_affiliation_strings":["Groupe de Recherche et d\u2019Etude du Ph\u00e9nom\u00e8ne Inflammatoire (GREPI)\u2010(EA2938) Laboratoire d\u2019Enzymologie, Centre Hospitalier Universitaire de Grenoble, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Groupe de Recherche et d\u2019Etude du Ph\u00e9nom\u00e8ne Inflammatoire (GREPI)\u2010(EA2938) Laboratoire d\u2019Enzymologie, Centre Hospitalier Universitaire de Grenoble, France","institution_ids":["https://openalex.org/I2800555055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111576813","display_name":"G\u00e9rard Klein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I177483745","display_name":"Universit\u00e9 Joseph Fourier","ror":"https://ror.org/02aj0kh94","country_code":"FR","type":"education","lineage":["https://openalex.org/I177483745","https://openalex.org/I899635006"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I3020098449","display_name":"CEA Grenoble","ror":"https://ror.org/02mg6n827","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I3020098449"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Gerard Klein","raw_affiliation_strings":["Laboratoire de Biochimie et Biophysique des Syst\u00e8mes Int\u00e9gr\u00e9s, UMR5092, CEA/CNRS/UJF, 17 rue des Martyrs, 38054 Grenoble, Cedex 9, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biochimie et Biophysique des Syst\u00e8mes Int\u00e9gr\u00e9s, UMR5092, CEA/CNRS/UJF, 17 rue des Martyrs, 38054 Grenoble, Cedex 9, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I177483745","https://openalex.org/I2738703131","https://openalex.org/I3020098449"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069666784","display_name":"Philippe Jean Sansonetti","orcid":"https://orcid.org/0000-0001-7542-4527","observed_orcids":["https://orcid.org/0000-0001-7542-4527"]},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Philippe Sansonetti","raw_affiliation_strings":["Institut Pasteur, Pathog\u00e9nie Microbienne Mol\u00e9culaire, 28, rue du Dr. Roux, 75724 Paris, Cedex 15, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Pathog\u00e9nie Microbienne Mol\u00e9culaire, 28, rue du Dr. Roux, 75724 Paris, Cedex 15, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091576168","display_name":"Steve J. Charette","orcid":"https://orcid.org/0000-0002-0199-2852","observed_orcids":["https://orcid.org/0000-0002-0199-2852"]},"institutions":[{"id":"https://openalex.org/I114457229","display_name":"University of Geneva","ror":"https://ror.org/01swzsf04","country_code":"CH","type":"education","lineage":["https://openalex.org/I114457229"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Steve J. Charette","raw_affiliation_strings":["Universit\u00e9 de Gen\u00e8ve, Centre M\u00e9dical Universitaire, D\u00e9partement de Physiologie Cellulaire et M\u00e9tabolisme, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Gen\u00e8ve, Centre M\u00e9dical Universitaire, D\u00e9partement de Physiologie Cellulaire et M\u00e9tabolisme, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland","institution_ids":["https://openalex.org/I114457229"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074290277","display_name":"Pierre Cosson","orcid":"https://orcid.org/0000-0002-4881-0358","observed_orcids":["https://orcid.org/0000-0002-4881-0358"]},"institutions":[{"id":"https://openalex.org/I114457229","display_name":"University of Geneva","ror":"https://ror.org/01swzsf04","country_code":"CH","type":"education","lineage":["https://openalex.org/I114457229"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Pierre Cosson","raw_affiliation_strings":["Universit\u00e9 de Gen\u00e8ve, Centre M\u00e9dical Universitaire, D\u00e9partement de Physiologie Cellulaire et M\u00e9tabolisme, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Gen\u00e8ve, Centre M\u00e9dical Universitaire, D\u00e9partement de Physiologie Cellulaire et M\u00e9tabolisme, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland","institution_ids":["https://openalex.org/I114457229"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2350,"currency":"USD","value_usd":2350},"apc_paid":null,"fwci":2.2777,"has_fulltext":false,"cited_by_count":135,"citation_normalized_percentile":{"value":0.87948998,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"8","issue":"1","first_page":"139","last_page":"148"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms","score":0.3433000147342682,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms","score":0.3433000147342682,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11916","display_name":"Legionella and Acanthamoeba research","score":0.21699999272823334,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.06989999860525131,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/klebsiella-pneumoniae","display_name":"Klebsiella pneumoniae","score":0.9649999737739563},{"id":"https://openalex.org/keywords/dictyostelium-discoideum","display_name":"Dictyostelium discoideum","score":0.953000009059906},{"id":"https://openalex.org/keywords/intracellular-killing","display_name":"intracellular killing","score":0.5979999899864197},{"id":"https://openalex.org/keywords/host-resistance-genes","display_name":"host resistance genes","score":0.8650000095367432},{"id":"https://openalex.org/keywords/sulfotransferase","display_name":"sulfotransferase","score":0.9729999899864197},{"id":"https://openalex.org/keywords/bacterial-virulence","display_name":"bacterial virulence","score":0.7239999771118164},{"id":"https://openalex.org/keywords/host-pathogen-interaction","display_name":"host-pathogen interaction","score":0.6819999814033508},{"id":"https://openalex.org/keywords/phagocytosis","display_name":"phagocytosis","score":0.8650000095367432}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9092123508453369},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.8600732088088989},{"id":"https://openalex.org/C2775969001","wikidata":"https://www.wikidata.org/wiki/Q134351","display_name":"Dictyostelium discoideum","level":3,"score":0.7496664524078369},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7406507730484009},{"id":"https://openalex.org/C2777700362","wikidata":"https://www.wikidata.org/wiki/Q107647","display_name":"Phagocyte","level":3,"score":0.6999596953392029},{"id":"https://openalex.org/C2777058267","wikidata":"https://www.wikidata.org/wiki/Q132592","display_name":"Klebsiella pneumoniae","level":4,"score":0.6886101365089417},{"id":"https://openalex.org/C2775889303","wikidata":"https://www.wikidata.org/wiki/Q17146891","display_name":"Dictyostelium","level":3,"score":0.6719449758529663},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.6556284427642822},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5978835225105286},{"id":"https://openalex.org/C160448771","wikidata":"https://www.wikidata.org/wiki/Q184726","display_name":"Phagocytosis","level":2,"score":0.5969653129577637},{"id":"https://openalex.org/C153726182","wikidata":"https://www.wikidata.org/wiki/Q3720909","display_name":"Intracellular parasite","level":3,"score":0.5241832137107849},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.4915338456630707},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.31434789299964905},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.12242808938026428}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004023","descriptor_name":"Dictyostelium","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D004023","descriptor_name":"Dictyostelium","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D004023","descriptor_name":"Dictyostelium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010587","descriptor_name":"Phagocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018410","descriptor_name":"Pneumonia, Bacterial","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018410","descriptor_name":"Pneumonia, Bacterial","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1111/j.1462-5822.2005.00607.x","doi":"https://doi.org/10.1111/j.1462-5822.2005.00607.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1462-5822.2005.00607.x","pdf_url":null,"source":{"id":"https://openalex.org/S113048938","display_name":"Cellular Microbiology","issn_l":"1462-5814","issn":["1462-5814","1462-5822"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Microbiology","raw_type":"journal-article"},{"id":"pmid:16367873","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16367873","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:unige.ch:unige:39521","doi":null,"is_oa":false,"landing_page_url":"https://archive-ouverte.unige.ch/unige:39521","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ISSN: 1462-5814","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:hal-00399573v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-00399573","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cellular Microbiology, 2006, 8 (1), pp.139-48. ⟨10.1111/j.1462-5822.2005.00607.x⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:unige.ch:aou:unige:39521","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:39521","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1462-5814","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:unige.ch:aou:unige:39521","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:39521","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1462-5814","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W1480837412","https://openalex.org/W1518079028","https://openalex.org/W1519269060","https://openalex.org/W1599496006","https://openalex.org/W1600119101","https://openalex.org/W1607493519","https://openalex.org/W1626599458","https://openalex.org/W1870905795","https://openalex.org/W1967325223","https://openalex.org/W1973643962","https://openalex.org/W1975404555","https://openalex.org/W1976835608","https://openalex.org/W1979513617","https://openalex.org/W1980564572","https://openalex.org/W1991894986","https://openalex.org/W2000554833","https://openalex.org/W2005222994","https://openalex.org/W2021750140","https://openalex.org/W2044293736","https://openalex.org/W2060823634","https://openalex.org/W2062290073","https://openalex.org/W2063855381","https://openalex.org/W2066515050","https://openalex.org/W2068805793","https://openalex.org/W2078795466","https://openalex.org/W2080534261","https://openalex.org/W2080849796","https://openalex.org/W2084814184","https://openalex.org/W2093427530","https://openalex.org/W2097951029","https://openalex.org/W2104817697","https://openalex.org/W2113120391","https://openalex.org/W2120450733","https://openalex.org/W2125782986","https://openalex.org/W2131227464","https://openalex.org/W2133320652","https://openalex.org/W2138805337","https://openalex.org/W2145946091","https://openalex.org/W2148407577","https://openalex.org/W2153664745","https://openalex.org/W2163960411","https://openalex.org/W2164402175","https://openalex.org/W2164578156","https://openalex.org/W2166097152","https://openalex.org/W2167727224","https://openalex.org/W2177433092","https://openalex.org/W2312482238"],"related_works":["https://openalex.org/W2091960114","https://openalex.org/W7096797916","https://openalex.org/W4309705208","https://openalex.org/W2101424792","https://openalex.org/W2027603386","https://openalex.org/W4385692541","https://openalex.org/W2037232766","https://openalex.org/W4241549614","https://openalex.org/W2157034645","https://openalex.org/W2800789600"],"abstract_inverted_index":{"The":[0,108],"amoeba":[1],"Dictyostelium":[2,38,114,146],"discoideum":[3],"shares":[4],"many":[5],"traits":[6],"with":[7],"mammalian":[8,30],"macrophages,":[9],"in":[10,62,85,113],"particular":[11],"the":[12,47,98,154],"ability":[13],"to":[14,26,39,59,82,116,137],"phagocytose":[15],"and":[16,29,76,80,103,159],"kill":[17],"bacteria.":[18],"In":[19],"response,":[20],"pathogenic":[21],"bacteria":[22,160],"use":[23],"conserved":[24],"mechanisms":[25],"fight":[27],"amoebae":[28],"phagocytes.":[31,92],"Here":[32],"we":[33],"developed":[34],"an":[35],"assay":[36],"using":[37],"monitor":[40],"phagocyte-bacteria":[41],"interactions.":[42],"Genetic":[43],"analysis":[44,142],"revealed":[45],"that":[46,60],"virulence":[48,151],"of":[49,88,97,101,110,120,143],"Klebsiella":[50],"pneumoniae":[51,90,139],"measured":[52],"by":[53,91],"this":[54,68],"test":[55],"is":[56,94,105],"very":[57],"similar":[58],"observed":[61],"a":[63,95,106,117,134,149],"mouse":[64],"pneumonia":[65],"model.":[66],"Using":[67],"assay,":[69],"two":[70],"new":[71],"host":[72,158],"resistance":[73],"genes":[74],"(PHG1":[75],"KIL1)":[77],"were":[78],"identified":[79],"shown":[81],"be":[83],"involved":[84],"intracellular":[86],"killing":[87],"K.":[89,124,138],"Phg1":[93],"member":[96],"9TM":[99],"family":[100],"proteins,":[102],"Kil1":[104],"sulphotransferase.":[107],"loss":[109],"PHG1":[111,131],"resulted":[112],"susceptibility":[115,136],"small":[118],"subset":[119],"bacterial":[121],"species":[122],"including":[123],"pneumoniae.":[125],"Remarkably,":[126],"Drosophila":[127],"mutants":[128,147],"deficient":[129],"for":[130],"also":[132],"exhibited":[133],"specific":[135],"infections.":[140],"Systematic":[141],"several":[144],"additional":[145],"created":[148],"two-dimensional":[150],"array,":[152],"where":[153],"complex":[155],"interactions":[156],"between":[157],"are":[161],"visualized.":[162]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}