{"id":"https://openalex.org/W2000218369","doi":"https://doi.org/10.1002/jssc.200900698","title":"Agglomerated silica monolithic column for hydrophilic interaction LC","display_name":"Agglomerated silica monolithic column for hydrophilic interaction LC","publication_year":2010,"publication_date":"2010-03-01","ids":{"openalex":"https://openalex.org/W2000218369","doi":"https://doi.org/10.1002/jssc.200900698","mag":"2000218369","pmid":"https://pubmed.ncbi.nlm.nih.gov/20222075"},"language":"en","primary_location":{"id":"doi:10.1002/jssc.200900698","doi":"https://doi.org/10.1002/jssc.200900698","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jssc.200900698","pdf_url":null,"source":{"id":"https://openalex.org/S45406943","display_name":"Journal of Separation Science","issn_l":"1615-9306","issn":["1615-9306","1615-9314"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Separation Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003914534","display_name":"Mohammed E. A. Ibrahim","orcid":"https://orcid.org/0000-0002-9251-9437","observed_orcids":["https://orcid.org/0000-0002-9251-9437"]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Mohammed E. A. Ibrahim","raw_affiliation_strings":["Department of Chemistry, University of Alberta, Edmonton, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Alberta, Edmonton, AB, Canada","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066583224","display_name":"Ting Zhou","orcid":"https://orcid.org/0000-0003-2276-7942","observed_orcids":["https://orcid.org/0000-0003-2276-7942"]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ting Zhou","raw_affiliation_strings":["Department of Chemistry, University of Alberta, Edmonton, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Alberta, Edmonton, AB, Canada","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026900423","display_name":"Charles A. Lucy","orcid":"https://orcid.org/0000-0002-5228-0169","observed_orcids":["https://orcid.org/0000-0002-5228-0169"]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Charles A. Lucy","raw_affiliation_strings":["Department of Chemistry, University of Alberta, Edmonton, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Alberta, Edmonton, AB, Canada","institution_ids":["https://openalex.org/I154425047"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5026900423"],"corresponding_institution_ids":["https://openalex.org/I154425047"],"apc_list":{"value":4030,"currency":"USD","value_usd":4030},"apc_paid":null,"fwci":1.6151,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.79959542,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"33","issue":"6-7","first_page":"773","last_page":"778"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13128","display_name":"Chromatography in Natural Products","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hydrophilic-interaction-liquid-chromatography","display_name":"hydrophilic interaction liquid chromatography","score":0.9729999899864197},{"id":"https://openalex.org/keywords/monolithic-silica-column","display_name":"monolithic silica column","score":0.9100000262260437},{"id":"https://openalex.org/keywords/electrostatic-binding","display_name":"electrostatic binding","score":0.7509999871253967},{"id":"https://openalex.org/keywords/acetonitrile-mobile-phase","display_name":"acetonitrile mobile phase","score":0.6549999713897705},{"id":"https://openalex.org/keywords/mass-transfer","display_name":"mass transfer","score":0.6890000104904175},{"id":"https://openalex.org/keywords/amino-acid-separation","display_name":"amino acid separation","score":0.7429999709129333},{"id":"https://openalex.org/keywords/nucleotides","display_name":"nucleotides","score":0.6159999966621399},{"id":"https://openalex.org/keywords/benzoate","display_name":"benzoate","score":0.9369999766349792},{"id":"https://openalex.org/keywords/pharmaceutical-separation","display_name":"drug separation","score":0.6869999766349792}],"concepts":[{"id":"https://openalex.org/C116817701","wikidata":"https://www.wikidata.org/wiki/Q5955221","display_name":"Hydrophilic interaction chromatography","level":3,"score":0.9037736654281616},{"id":"https://openalex.org/C152815550","wikidata":"https://www.wikidata.org/wiki/Q653208","display_name":"Monolith","level":3,"score":0.8440275192260742},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7824406623840332},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.727851152420044},{"id":"https://openalex.org/C134871310","wikidata":"https://www.wikidata.org/wiki/Q6901686","display_name":"Monolithic HPLC column","level":3,"score":0.5300151109695435},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.2784727215766907},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1521131694316864},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D012822","descriptor_name":"Silicon Dioxide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D055672","descriptor_name":"Static Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/jssc.200900698","doi":"https://doi.org/10.1002/jssc.200900698","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jssc.200900698","pdf_url":null,"source":{"id":"https://openalex.org/S45406943","display_name":"Journal of Separation Science","issn_l":"1615-9306","issn":["1615-9306","1615-9314"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Separation Science","raw_type":"journal-article"},{"id":"pmid:20222075","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20222075","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of separation science","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320319946","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W147809265","https://openalex.org/W184869612","https://openalex.org/W597607036","https://openalex.org/W1965832363","https://openalex.org/W1966533104","https://openalex.org/W1978881812","https://openalex.org/W1998852865","https://openalex.org/W2001195021","https://openalex.org/W2003190221","https://openalex.org/W2020017970","https://openalex.org/W2031234986","https://openalex.org/W2034732754","https://openalex.org/W2037584292","https://openalex.org/W2042788677","https://openalex.org/W2047012816","https://openalex.org/W2054235690","https://openalex.org/W2058796576","https://openalex.org/W2059995265","https://openalex.org/W2070144623","https://openalex.org/W2074553402","https://openalex.org/W2079393314","https://openalex.org/W2080038602","https://openalex.org/W2091209489","https://openalex.org/W2093268283","https://openalex.org/W2099756906","https://openalex.org/W2117733265","https://openalex.org/W2131414490","https://openalex.org/W2160575064","https://openalex.org/W2410372681","https://openalex.org/W4285719527","https://openalex.org/W4300103251"],"related_works":["https://openalex.org/W2070144623","https://openalex.org/W2802229868","https://openalex.org/W1966533104","https://openalex.org/W2350607677","https://openalex.org/W2037542029","https://openalex.org/W2097386374","https://openalex.org/W1966709166","https://openalex.org/W6987174129","https://openalex.org/W2042112889","https://openalex.org/W7062296060"],"abstract_inverted_index":{"Hydrophilic":[0],"interaction":[1,153],"LC":[2],"(HILIC)":[3],"has":[4],"gained":[5],"wide":[6],"acceptance":[7],"in":[8,100,145],"recent":[9],"years":[10],"due":[11],"to":[12,15,91,139],"its":[13],"ability":[14],"retain":[16,74],"and":[17,78,93,108,120],"separate":[18],"polar":[19],"compounds":[20],"such":[21,116],"as":[22,117,166],"pharmaceuticals.":[23],"Most":[24],"commercial":[25],"HILIC":[26,37,112,137],"phases":[27,73],"are":[28,47,123],"particle":[29],"based,":[30],"which":[31,36],"limit":[32],"the":[33,65,75,81,86,101,106,158],"speed":[34],"with":[35,111,125,142],"separations":[38,138],"can":[39],"be":[40,140],"performed.":[41],"Herein,":[42],"agglomerated":[43,87],"silica":[44,57,70,83],"monolithic":[45],"columns":[46],"prepared":[48],"by":[49,59],"electrostatically":[50],"attaching":[51],"polyionic":[52],"latex":[53,67],"particles":[54],"onto":[55],"a":[56,62,69],"monolith":[58],"simply":[60],"flushing":[61],"suspension":[63],"of":[64,80,128,134,157],"ionic":[66],"through":[68],"monolith.":[71],"Such":[72],"high":[76,132],"efficiency":[77,107],"permeability":[79,133],"native":[82],"monolith,":[84],"while":[85],"phase":[88,103],"is":[89,161],"easy":[90],"introduce":[92],"provides":[94],"excellent":[95],"mass":[96],"transfer.":[97],"High":[98],"%ACN":[99],"mobile":[102],"dramatically":[104],"increases":[105],"retention,":[109],"consistent":[110],"behavior.":[113],"Test":[114],"analytes":[115],"benzoates,":[118],"nucleotides":[119],"amino":[121,164],"acids":[122,165],"separated":[124],"plate":[126],"heights":[127],"25-110":[129],"microm.":[130],"The":[131],"monoliths":[135,160],"allows":[136],"performed":[141],"baseline":[143],"resolution":[144],"less":[146],"than":[147],"15":[148],"s.":[149],"Electrostatic":[150],"repulsion-hydrophilic":[151],"liquid":[152],"chromatographic":[154],"retention":[155],"behavior":[156],"latex-coated":[159],"verified":[162],"using":[163],"test":[167],"analytes.":[168]},"counts_by_year":[{"year":2023,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}