{"id":"https://openalex.org/W2000202031","doi":"https://doi.org/10.1111/j.1651-2227.2009.01648.x","title":"Complications affecting preterm neonates from 1991 to 2006: what have we gained?","display_name":"Complications affecting preterm neonates from 1991 to 2006: what have we gained?","publication_year":2010,"publication_date":"2010-02-01","ids":{"openalex":"https://openalex.org/W2000202031","doi":"https://doi.org/10.1111/j.1651-2227.2009.01648.x","mag":"2000202031","pmid":"https://pubmed.ncbi.nlm.nih.gov/20064132"},"language":"en","primary_location":{"id":"doi:10.1111/j.1651-2227.2009.01648.x","doi":"https://doi.org/10.1111/j.1651-2227.2009.01648.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1651-2227.2009.01648.x","pdf_url":null,"source":{"id":"https://openalex.org/S178469169","display_name":"Acta Paediatrica","issn_l":"0365-1436","issn":["0365-1436","0803-5253","1651-2227"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Paediatrica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091885878","display_name":"Floris Groenendaal","orcid":"https://orcid.org/0000-0002-9284-1637","observed_orcids":["https://orcid.org/0000-0002-9284-1637"]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]},{"id":"https://openalex.org/I4210162850","display_name":"Wilhelmina Children's Hospital","ror":"https://ror.org/05fqypv61","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916","https://openalex.org/I4210162850"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"F Groenendaal","raw_affiliation_strings":["Department of Neonatology, Perinatal Centre, Wilhelmina Children's Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands. f.groenendaal@umcutrecht.nl","Department of Neonatology, Perinatal Centre, Wilhelmina Children\u2019s Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neonatology, Perinatal Centre, Wilhelmina Children's Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands. f.groenendaal@umcutrecht.nl","institution_ids":["https://openalex.org/I4210162850"]},{"raw_affiliation_string":"Department of Neonatology, Perinatal Centre, Wilhelmina Children\u2019s Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916","https://openalex.org/I4210162850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108646654","display_name":"Jacqueline U. M. Termote","orcid":"https://orcid.org/0000-0002-8522-6599","observed_orcids":["https://orcid.org/0000-0002-8522-6599"]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]},{"id":"https://openalex.org/I4210162850","display_name":"Wilhelmina Children's Hospital","ror":"https://ror.org/05fqypv61","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916","https://openalex.org/I4210162850"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"JUM Termote","raw_affiliation_strings":["Department of Neonatology, Perinatal Centre, Wilhelmina Children\u2019s Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neonatology, Perinatal Centre, Wilhelmina Children\u2019s Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916","https://openalex.org/I4210162850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086696826","display_name":"Marja van der Heide-Jalving","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]},{"id":"https://openalex.org/I4210162850","display_name":"Wilhelmina Children's Hospital","ror":"https://ror.org/05fqypv61","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916","https://openalex.org/I4210162850"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"M Van Der Heide\u2010Jalving","raw_affiliation_strings":["Department of Neonatology, Perinatal Centre, Wilhelmina Children\u2019s Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neonatology, Perinatal Centre, Wilhelmina Children\u2019s Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916","https://openalex.org/I4210162850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111608601","display_name":"Ingrid C. van Haastert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]},{"id":"https://openalex.org/I4210162850","display_name":"Wilhelmina Children's Hospital","ror":"https://ror.org/05fqypv61","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916","https://openalex.org/I4210162850"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"IC Van Haastert","raw_affiliation_strings":["Department of Neonatology, Perinatal Centre, Wilhelmina Children\u2019s Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neonatology, Perinatal Centre, Wilhelmina Children\u2019s Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916","https://openalex.org/I4210162850"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038391182","display_name":"Linda S. de Vries","orcid":"https://orcid.org/0000-0002-7282-8304","observed_orcids":["https://orcid.org/0000-0002-7282-8304"]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]},{"id":"https://openalex.org/I4210162850","display_name":"Wilhelmina Children's Hospital","ror":"https://ror.org/05fqypv61","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916","https://openalex.org/I4210162850"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"LS De Vries","raw_affiliation_strings":["Department of Neonatology, Perinatal Centre, Wilhelmina Children\u2019s Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neonatology, Perinatal Centre, Wilhelmina Children\u2019s Hospital/University Medical Centre Utrecht, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916","https://openalex.org/I4210162850"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5091885878"],"corresponding_institution_ids":["https://openalex.org/I3018483916","https://openalex.org/I4210162850"],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":null,"fwci":11.4539,"has_fulltext":false,"cited_by_count":99,"citation_normalized_percentile":{"value":0.98709032,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"99","issue":"3","first_page":"354","last_page":"358"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11060","display_name":"Infant Development and Preterm Care","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11060","display_name":"Infant Development and Preterm Care","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.025699999183416367,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.009999999776482582,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/preterm-infants","display_name":"preterm infants","score":0.9449999928474426},{"id":"https://openalex.org/keywords/neonatal-morbidity","display_name":"neonatal morbidity","score":0.7049999833106995},{"id":"https://openalex.org/keywords/neonatal-mortality","display_name":"neonatal mortality","score":0.9860000014305115},{"id":"https://openalex.org/keywords/chronic-lung-disease-of-prematurity","display_name":"chronic lung disease of prematurity","score":0.8939999938011169},{"id":"https://openalex.org/keywords/intraventricular-hemorrhage","display_name":"intraventricular hemorrhage","score":0.996999979019165},{"id":"https://openalex.org/keywords/cystic-periventricular-leukomalacia","display_name":"cystic periventricular leukomalacia","score":0.9480000138282776},{"id":"https://openalex.org/keywords/necrotizing-enterocolitis","display_name":"necrotizing enterocolitis","score":0.972000002861023},{"id":"https://openalex.org/keywords/retinopathy-of-prematurity","display_name":"retinopathy of prematurity","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cerebral-palsy","display_name":"cerebral palsy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/survival-trends","display_name":"survival trends","score":0.4440000057220459},{"id":"https://openalex.org/keywords/neonatal-intensive-care-outcomes","display_name":"neonatal intensive care outcomes","score":0.5120000243186951}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9706523418426514},{"id":"https://openalex.org/C2779303187","wikidata":"https://www.wikidata.org/wiki/Q10859678","display_name":"Necrotizing enterocolitis","level":2,"score":0.8342915773391724},{"id":"https://openalex.org/C2779918416","wikidata":"https://www.wikidata.org/wiki/Q1423087","display_name":"Retinopathy of prematurity","level":4,"score":0.8092135190963745},{"id":"https://openalex.org/C2780123866","wikidata":"https://www.wikidata.org/wiki/Q469490","display_name":"Periventricular leukomalacia","level":4,"score":0.6914511919021606},{"id":"https://openalex.org/C2779421357","wikidata":"https://www.wikidata.org/wiki/Q210427","display_name":"Cerebral palsy","level":2,"score":0.6880749464035034},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.6361389756202698},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.5962517857551575},{"id":"https://openalex.org/C2779252433","wikidata":"https://www.wikidata.org/wiki/Q6058597","display_name":"Intraventricular hemorrhage","level":4,"score":0.4411676824092865},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.23988384008407593},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007226","descriptor_name":"Infant Mortality","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007235","descriptor_name":"Infant, Premature, Diseases","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D007235","descriptor_name":"Infant, Premature, Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D007235","descriptor_name":"Infant, Premature, Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D007363","descriptor_name":"Intensive Care Units, Neonatal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015931","descriptor_name":"Intensive Care, Neonatal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017063","descriptor_name":"Outcome Assessment, Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1651-2227.2009.01648.x","doi":"https://doi.org/10.1111/j.1651-2227.2009.01648.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1651-2227.2009.01648.x","pdf_url":null,"source":{"id":"https://openalex.org/S178469169","display_name":"Acta Paediatrica","issn_l":"0365-1436","issn":["0365-1436","0803-5253","1651-2227"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Paediatrica","raw_type":"journal-article"},{"id":"pmid:20064132","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20064132","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta paediatrica (Oslo, Norway : 1992)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W108780264","https://openalex.org/W114326792","https://openalex.org/W336466729","https://openalex.org/W336974305","https://openalex.org/W1541915837","https://openalex.org/W1544670697","https://openalex.org/W1579450354","https://openalex.org/W1583020440","https://openalex.org/W1755329430","https://openalex.org/W1974506522","https://openalex.org/W1975730665","https://openalex.org/W1989727196","https://openalex.org/W1996498221","https://openalex.org/W2000126618","https://openalex.org/W2002714822","https://openalex.org/W2007644749","https://openalex.org/W2016693709","https://openalex.org/W2029855152","https://openalex.org/W2046224781","https://openalex.org/W2055289497","https://openalex.org/W2067292954","https://openalex.org/W2106641369","https://openalex.org/W2112468487","https://openalex.org/W2112915598","https://openalex.org/W2113594794","https://openalex.org/W2150258792","https://openalex.org/W2153817505","https://openalex.org/W2397801951","https://openalex.org/W2401259908","https://openalex.org/W2416922384","https://openalex.org/W2594344992","https://openalex.org/W3148465273","https://openalex.org/W4248231685"],"related_works":["https://openalex.org/W3093347882","https://openalex.org/W2170466537","https://openalex.org/W2168830122","https://openalex.org/W4380447683","https://openalex.org/W1988865402","https://openalex.org/W6910827180","https://openalex.org/W2418320410","https://openalex.org/W1974653633","https://openalex.org/W3197007375","https://openalex.org/W7171560897"],"abstract_inverted_index":{"AIM:":[0],"In":[1],"this":[2],"study,":[3],"we":[4],"determined":[5],"whether":[6],"outcome":[7],"of":[8,16,27,63,156,193],"preterm":[9,162],"neonates":[10,22,149],"has":[11],"improved":[12,166],"over":[13],"a":[14,24,169,179,191],"period":[15,83,89,128,146,152],"16":[17],"years.":[18],"STUDY":[19],"DESIGN:":[20],"Inborn":[21,161],"with":[23,33],"gestational":[25],"age":[26],"25.0-29.9":[28],"weeks":[29],"were":[30,37,72,153],"included.":[31],"Patients":[32],"severe":[34,61],"congenital":[35],"malformations":[36],"excluded.":[38],"Mortality":[39],"and":[40,68,121,168,174,184,188],"morbidity":[41],"(chronic":[42],"lung":[43],"disease;":[44],"CLD,":[45],"intraventricular":[46],"haemorrhage:":[47],"IVH":[48,118,185],"grade":[49,119,186],"III":[50,120,187],"or":[51],"IV,":[52],"cystic":[53],"periventricular":[54],"leukomalacia:":[55],"cPVL,":[56],"perforated":[57],"necrotizing":[58],"enterocolitis:":[59],"NEC,":[60],"retinopathy":[62],"prematurity":[64],"needing":[65],"surgery:":[66],"ROP":[67],"cerebral":[69],"palsy:":[70],"CP)":[71],"compared":[73],"in":[74,127,145,150,154,172],"three":[75],"periods":[76,109],"(period":[77],"1:":[78],"1991-1996":[79],"n":[80,86,92],"=":[81,87,93],"434;":[82],"2:":[84],"1997-2001":[85],"356;":[88],"3:":[90],"2002-2006":[91],"422).":[94],"RESULTS:":[95],"Infant":[96],"mortality":[97],"decreased":[98,113,132,140],"from":[99,114,134,141],"15.2%":[100],"to":[101,116,136,143,181],"10.9%.":[102],"CLD":[103,183],"did":[104],"not":[105],"differ":[106],"significantly":[107,133],"between":[108],"(14.1-14.8%).":[110],"Perforated":[111,176],"NEC":[112,177],"2.8%":[115],"1.6%.":[117,137],"IV":[122,189],"both":[123],"remained":[124],"at":[125],"5.7%":[126],"3,":[129],"whereas":[130],"cPVL":[131,173],"4.5%":[135],"Cerebral":[138],"palsy":[139],"5.8%":[142],"3.5%":[144],"3.":[147],"Two":[148],"each":[151],"need":[155],"surgery":[157],"for":[158],"ROP.":[159],"CONCLUSION:":[160],"patients":[163],"showed":[164,178],"an":[165],"survival":[167],"significant":[170],"reduction":[171],"CP.":[175],"trend":[180],"decrease.":[182],"remain":[190],"matter":[192],"concern.":[194]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
