{"id":"https://openalex.org/W2000200955","doi":"https://doi.org/10.1016/s0969-2126(99)80044-6","title":"Design of sequences with good folding properties in coarse-grained protein models","display_name":"Design of sequences with good folding properties in coarse-grained protein models","publication_year":1999,"publication_date":"1999-03-01","ids":{"openalex":"https://openalex.org/W2000200955","doi":"https://doi.org/10.1016/s0969-2126(99)80044-6","mag":"2000200955","pmid":"https://pubmed.ncbi.nlm.nih.gov/10368303"},"language":"en","primary_location":{"id":"doi:10.1016/s0969-2126(99)80044-6","doi":"https://doi.org/10.1016/s0969-2126(99)80044-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0969-2126(99)80044-6","pdf_url":"http://www.cell.com/article/S0969212699800446/pdf","source":{"id":"https://openalex.org/S7112016","display_name":"Structure","issn_l":"0969-2126","issn":["0969-2126","1878-4186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Structure","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["arxiv","crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0969212699800446/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060442147","display_name":"Anders Irb\u00e4ck","orcid":"https://orcid.org/0000-0003-1384-0626","observed_orcids":["https://orcid.org/0000-0003-1384-0626"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Anders Irb\u00e4ck","raw_affiliation_strings":["Complex Systems Group, Department of Theoretical Physics, University of Lund, S\u00f6lvegatan 14A S-223 62 Lund, Sweden. irback@thep.lu.se","Complex Systems Group, Department of Theoretical Physics, University of Lund, S\u00f6lvegatan 14A, S-223 62, Lund, Sweden e-mail:","[email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Complex Systems Group, Department of Theoretical Physics, University of Lund, S\u00f6lvegatan 14A S-223 62 Lund, Sweden. irback@thep.lu.se","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Complex Systems Group, Department of Theoretical Physics, University of Lund, S\u00f6lvegatan 14A, S-223 62, Lund, Sweden e-mail:","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"[email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057866050","display_name":"Carsten Peterson","orcid":"https://orcid.org/0000-0001-7362-2191","observed_orcids":["https://orcid.org/0000-0001-7362-2191"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Carsten Peterson","raw_affiliation_strings":["Complex Systems Group, Department of Theoretical Physics, University of Lund, S\u00f6lvegatan 14A, S-223 62, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Complex Systems Group, Department of Theoretical Physics, University of Lund, S\u00f6lvegatan 14A, S-223 62, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060689614","display_name":"Fra\u0144k Potthast","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Frank Potthast","raw_affiliation_strings":["Astra H\u00e4ssle AB, Preclinical R&D, Research Informatics, S-431 83, M\u00f6lndal, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Astra H\u00e4ssle AB, Preclinical R&D, Research Informatics, S-431 83, M\u00f6lndal, Sweden","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"Erik Sandelin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Erik Sandelin","raw_affiliation_strings":["Complex Systems Group, Department of Theoretical Physics, University of Lund, S\u00f6lvegatan 14A, S-223 62, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Complex Systems Group, Department of Theoretical Physics, University of Lund, S\u00f6lvegatan 14A, S-223 62, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5060442147"],"corresponding_institution_ids":["https://openalex.org/I187531555"],"apc_list":{"value":9350,"currency":"USD","value_usd":9350},"apc_paid":null,"fwci":0.6891,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.65259986,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"7","issue":"3","first_page":"347","last_page":"360"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-sequence-design","display_name":"protein sequence design","score":0.9229999780654907},{"id":"https://openalex.org/keywords/coarse-grained-protein-models","display_name":"coarse-grained protein models","score":0.8659999966621399},{"id":"https://openalex.org/keywords/protein-folding","display_name":"protein folding","score":0.6240000128746033},{"id":"https://openalex.org/keywords/hydrophobic-polar-model","display_name":"hydrophobic-polar model","score":0.7480000257492065},{"id":"https://openalex.org/keywords/off-lattice-model","display_name":"off-lattice model","score":0.8100000023841858},{"id":"https://openalex.org/keywords/conformational-search","display_name":"conformational search","score":0.6629999876022339}],"concepts":[{"id":"https://openalex.org/C19499675","wikidata":"https://www.wikidata.org/wiki/Q232207","display_name":"Monte Carlo method","level":2,"score":0.7636876106262207},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.5802684426307678},{"id":"https://openalex.org/C2781204021","wikidata":"https://www.wikidata.org/wiki/Q6497091","display_name":"Lattice (music)","level":2,"score":0.5473220944404602},{"id":"https://openalex.org/C14961307","wikidata":"https://www.wikidata.org/wiki/Q5377176","display_name":"Energy minimization","level":2,"score":0.5043121576309204},{"id":"https://openalex.org/C204328495","wikidata":"https://www.wikidata.org/wiki/Q847556","display_name":"Protein folding","level":2,"score":0.4953831434249878},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4941237270832062},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.47998282313346863},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.4538109302520752},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.292685329914093},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.20539158582687378},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.20528921484947205},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.1990615427494049},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.07573649287223816},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009010","descriptor_name":"Monte Carlo Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":8,"locations":[{"id":"doi:10.1016/s0969-2126(99)80044-6","doi":"https://doi.org/10.1016/s0969-2126(99)80044-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0969-2126(99)80044-6","pdf_url":"http://www.cell.com/article/S0969212699800446/pdf","source":{"id":"https://openalex.org/S7112016","display_name":"Structure","issn_l":"0969-2126","issn":["0969-2126","1878-4186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Structure","raw_type":"journal-article"},{"id":"pmid:10368303","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10368303","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Structure (London, England : 1993)","raw_type":"Journal Article"},{"id":"pmh:oai:arXiv.org:cond-mat/9809415","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/cond-mat/9809415","pdf_url":"https://arxiv.org/pdf/cond-mat/9809415","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"mag:2951216160","doi":null,"is_oa":true,"landing_page_url":"https://arxiv.org/pdf/cond-mat/9809415v2","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"arXiv (Cornell University)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.242.2080","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.242.2080","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://arxiv.org/pdf/cond-mat/9809415v2.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.33.3624","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.33.3624","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.thep.lu.se/pub/Preprints/98/lu_tp_98_10.ps.gz","raw_type":"text"},{"id":"pmh:oai:lup.lub.lu.se:6e918aaa-2115-41b4-8ba8-892ff71383fd","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/6e918aaa-2115-41b4-8ba8-892ff71383fd","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 0969-2126","raw_type":"info:eu-repo/semantics/article"},{"id":"doi:10.48550/arxiv.cond-mat/9809415","doi":"https://doi.org/10.48550/arxiv.cond-mat/9809415","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.cond-mat/9809415","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1016/s0969-2126(99)80044-6","doi":"https://doi.org/10.1016/s0969-2126(99)80044-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0969-2126(99)80044-6","pdf_url":"http://www.cell.com/article/S0969212699800446/pdf","source":{"id":"https://openalex.org/S7112016","display_name":"Structure","issn_l":"0969-2126","issn":["0969-2126","1878-4186"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Structure","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"display_name":"Affordable and clean energy","score":0.8899999856948853,"id":"https://metadata.un.org/sdg/7"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320940","display_name":"Stiftelsen f\u00f6r\u00a0Strategisk Forskning","ror":"https://ror.org/044wr7g58"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2000200955.pdf"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W295995462","https://openalex.org/W1559700605","https://openalex.org/W1978885914","https://openalex.org/W1979754565","https://openalex.org/W1983628095","https://openalex.org/W1984148408","https://openalex.org/W1984313562","https://openalex.org/W1984527736","https://openalex.org/W1988690429","https://openalex.org/W1991315324","https://openalex.org/W1993321394","https://openalex.org/W2009467983","https://openalex.org/W2023235722","https://openalex.org/W2023608072","https://openalex.org/W2026702035","https://openalex.org/W2028841335","https://openalex.org/W2056760934","https://openalex.org/W2060287439","https://openalex.org/W2062175659","https://openalex.org/W2071164291","https://openalex.org/W2071436951","https://openalex.org/W2072843928","https://openalex.org/W2083174976","https://openalex.org/W2089435371","https://openalex.org/W2092637963","https://openalex.org/W2092732430","https://openalex.org/W2139415631","https://openalex.org/W2159643987","https://openalex.org/W2171546617","https://openalex.org/W2769722149","https://openalex.org/W3103568689"],"related_works":["https://openalex.org/W7096301419","https://openalex.org/W2123597834","https://openalex.org/W2028328730","https://openalex.org/W2963474859","https://openalex.org/W1991315324","https://openalex.org/W7100254428","https://openalex.org/W7099370089","https://openalex.org/W7096492634","https://openalex.org/W7097602217","https://openalex.org/W2060287439"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}