{"id":"https://openalex.org/W1999916640","doi":"https://doi.org/10.1089/jir.2008.0103","title":"Identification of Chicken Granulocyte Colony-Stimulating Factor (G-CSF/CSF3): The Previously Described Myelomonocytic Growth Factor Is Actually CSF3","display_name":"Identification of Chicken Granulocyte Colony-Stimulating Factor (G-CSF/CSF3): The Previously Described Myelomonocytic Growth Factor Is Actually CSF3","publication_year":2009,"publication_date":"2009-05-14","ids":{"openalex":"https://openalex.org/W1999916640","doi":"https://doi.org/10.1089/jir.2008.0103","mag":"1999916640","pmid":"https://pubmed.ncbi.nlm.nih.gov/19441885"},"language":"en","primary_location":{"id":"doi:10.1089/jir.2008.0103","doi":"https://doi.org/10.1089/jir.2008.0103","is_oa":false,"landing_page_url":"https://doi.org/10.1089/jir.2008.0103","pdf_url":null,"source":{"id":"https://openalex.org/S109620152","display_name":"Journal of Interferon & Cytokine Research","issn_l":"1079-9907","issn":["1079-9907","1557-7465"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Interferon & Cytokine Research","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1999916640"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034330463","display_name":"Mark S. Gibson","orcid":"https://orcid.org/0000-0001-9732-8915","observed_orcids":["https://orcid.org/0000-0001-9732-8915"]},"institutions":[{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mark S. Gibson","raw_affiliation_strings":["Institute for Animal Health, Compton, Berkshire, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Animal Health, Compton, Berkshire, United Kingdom","institution_ids":["https://openalex.org/I1287548271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111551123","display_name":"Pete Kaiser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Pete Kaiser","raw_affiliation_strings":["Institute for Animal Health, Compton, Berkshire, United Kingdom","Royal (Dick) School of Veterinary Studies"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Animal Health, Compton, Berkshire, United Kingdom","institution_ids":["https://openalex.org/I1287548271"]},{"raw_affiliation_string":"Royal (Dick) School of Veterinary Studies","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046358578","display_name":"Mark S. Fife","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287548271","display_name":"The Pirbright Institute","ror":"https://ror.org/04xv01a59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1287548271","https://openalex.org/I2799693246","https://openalex.org/I4210087105"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mark Fife","raw_affiliation_strings":["Institute for Animal Health, Compton, Berkshire, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Animal Health, Compton, Berkshire, United Kingdom","institution_ids":["https://openalex.org/I1287548271"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9646,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.74200673,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"29","issue":"6","first_page":"339","last_page":"344"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.8984000086784363,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.8984000086784363,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.013100000098347664,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chickens","display_name":"chickens","score":0.6940000057220459},{"id":"https://openalex.org/keywords/granulocyte-colony-stimulating-factor","display_name":"granulocyte colony-stimulating factor","score":0.9879999756813049},{"id":"https://openalex.org/keywords/mgf","display_name":"MGF","score":0.6389999985694885},{"id":"https://openalex.org/keywords/chicken-genome","display_name":"chicken genome","score":0.5759999752044678},{"id":"https://openalex.org/keywords/synteny","display_name":"synteny","score":0.6589999794960022},{"id":"https://openalex.org/keywords/primer-walking","display_name":"primer walking","score":0.8519999980926514},{"id":"https://openalex.org/keywords/gene-nomenclature","display_name":"gene nomenclature","score":0.5799999833106995},{"id":"https://openalex.org/keywords/hematopoietic-growth-factors","display_name":"hematopoietic growth factors","score":0.7210000157356262}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7439635396003723},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6808767318725586},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6702955961227417},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4867093861103058},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.41450512409210205}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012689","descriptor_name":"Sequence Homology, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016179","descriptor_name":"Granulocyte Colony-Stimulating Factor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016386","descriptor_name":"Chromosome Walking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022423","descriptor_name":"Myeloid Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D022423","descriptor_name":"Myeloid Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D026801","descriptor_name":"Synteny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030161","descriptor_name":"Avian Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D036341","descriptor_name":"Intercellular Signaling Peptides and Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1089/jir.2008.0103","doi":"https://doi.org/10.1089/jir.2008.0103","is_oa":false,"landing_page_url":"https://doi.org/10.1089/jir.2008.0103","pdf_url":null,"source":{"id":"https://openalex.org/S109620152","display_name":"Journal of Interferon & Cytokine Research","issn_l":"1079-9907","issn":["1079-9907","1557-7465"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Interferon & Cytokine Research","raw_type":"journal-article"},{"id":"pmid:19441885","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19441885","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W233798586","https://openalex.org/W946325369","https://openalex.org/W1493921847","https://openalex.org/W1979178750","https://openalex.org/W2024367831","https://openalex.org/W2056588747","https://openalex.org/W2059368294","https://openalex.org/W2061341693","https://openalex.org/W2063680739","https://openalex.org/W2076526919","https://openalex.org/W2077137690","https://openalex.org/W2090536334","https://openalex.org/W2122286498","https://openalex.org/W2126217218","https://openalex.org/W2132360036","https://openalex.org/W4292239814"],"related_works":["https://openalex.org/W2122286498","https://openalex.org/W803871156","https://openalex.org/W2114767865","https://openalex.org/W2093074784","https://openalex.org/W2559489370","https://openalex.org/W343747522","https://openalex.org/W48736676","https://openalex.org/W946325369","https://openalex.org/W2057532142"],"abstract_inverted_index":{"The":[0,55],"current":[1],"chicken":[2,60],"genome":[3,61],"build":[4],"contains":[5],"only":[6],"a":[7,73,98,108,149],"single":[8],"colony-stimulating":[9],"factor":[10,40],"(CSF)":[11],"gene,":[12],"granulocyte/macrophage":[13],"(GM)-CSF":[14],"(CSF2).":[15],"However,":[16],"genes":[17],"encoding":[18],"receptors":[19],"for":[20],"two":[21],"other":[22,87],"CSFs,":[23],"G-CSF":[24],"(CSF3)":[25],"and":[26,118,125,135,167,185],"M-CSF":[27],"(CSF1),":[28],"are":[29],"present":[30],"in":[31,85,132],"the":[32,53,59,65,93,103,115,142,157,164,172,177],"genome.":[33,54],"Another":[34],"apparently":[35],"chicken-specific":[36],"CSF,":[37],"myelomonocytic":[38],"growth":[39],"(MGF),":[41],"shares":[42],"substantial":[43],"sequence":[44,110,143,159,183],"homology":[45],"with":[46,80,102],"mammalian":[47],"CSF3":[48,66,95,134],"but":[49],"is":[50,131],"absent":[51],"from":[52],"putative":[56],"region":[57,100,166,174],"of":[58,92,107,114,163,171],"that":[62,129,176,187],"should":[63,189],"contain":[64],"ortholog,":[67],"while":[68],"not":[69],"currently":[70],"mapped":[71],"to":[72,122,155],"specific":[74],"chromosome,":[75],"exhibits":[76],"considerable":[77],"conserved":[78],"synteny":[79],"loci":[81],"containing":[82],"this":[83,147,182],"gene":[84,137,179],"several":[86],"species.":[88],"In":[89,112],"silico":[90],"analysis":[91,170],"predicted":[94,128],"location":[96],"revealed":[97],"large":[99,109],"homologous":[101],"MGF":[104,124,130,178],"promoter,":[105],"upstream":[106],"gap.":[111,144,160],"view":[113],"many":[116],"structural":[117],"functional":[119],"features":[120],"common":[121],"both":[123],"huCSF3,":[126],"we":[127],"fact":[133],"its":[136],"would":[138],"be":[139,190],"located":[140],"within":[141,181],"To":[145],"validate":[146],"hypothesis,":[148],"primer":[150],"walking":[151],"strategy":[152],"was":[153],"used":[154],"bridge":[156],"genomic":[158],"Full-length":[161],"sequencing":[162],"entire":[165],"thorough,":[168],"detailed":[169],"coding":[173],"confirmed":[175],"lay":[180],"gap,":[184],"therefore":[186],"it":[188],"renamed":[191],"CSF3.":[192]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}