{"id":"https://openalex.org/W1999428692","doi":"https://doi.org/10.1248/bpb.27.29","title":"The Immune-Enhancing Effect of the Herbal Combination Bouum-Myunyuk-Dan","display_name":"The Immune-Enhancing Effect of the Herbal Combination Bouum-Myunyuk-Dan","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W1999428692","doi":"https://doi.org/10.1248/bpb.27.29","mag":"1999428692","pmid":"https://pubmed.ncbi.nlm.nih.gov/14709894"},"language":"en","primary_location":{"id":"doi:10.1248/bpb.27.29","doi":"https://doi.org/10.1248/bpb.27.29","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.27.29","pdf_url":"https://www.jstage.jst.go.jp/article/bpb/27/1/27_1_29/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/bpb/27/1/27_1_29/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071734744","display_name":"Hyun\u2010Ja Jeong","orcid":"https://orcid.org/0000-0001-7559-0373","observed_orcids":["https://orcid.org/0000-0001-7559-0373"]},"institutions":[{"id":"https://openalex.org/I35928602","display_name":"Kyung Hee University","ror":"https://ror.org/01zqcg218","country_code":"KR","type":"education","lineage":["https://openalex.org/I35928602"]},{"id":"https://openalex.org/I77079311","display_name":"Wonkwang University","ror":"https://ror.org/006776986","country_code":"KR","type":"education","lineage":["https://openalex.org/I77079311"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyun-Ja Jeong","raw_affiliation_strings":["Department of Oriental Pharmacy, College of Pharmacy, VCRC of Wonkwang University","Department of Pharmacology, College of Oriental Medicine, Kyung Hee University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oriental Pharmacy, College of Pharmacy, VCRC of Wonkwang University","institution_ids":["https://openalex.org/I77079311"]},{"raw_affiliation_string":"Department of Pharmacology, College of Oriental Medicine, Kyung Hee University","institution_ids":["https://openalex.org/I35928602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056367866","display_name":"Hwan\u2010Suck Chung","orcid":"https://orcid.org/0000-0002-5901-0217","observed_orcids":["https://orcid.org/0000-0002-5901-0217"]},"institutions":[{"id":"https://openalex.org/I35928602","display_name":"Kyung Hee University","ror":"https://ror.org/01zqcg218","country_code":"KR","type":"education","lineage":["https://openalex.org/I35928602"]},{"id":"https://openalex.org/I77079311","display_name":"Wonkwang University","ror":"https://ror.org/006776986","country_code":"KR","type":"education","lineage":["https://openalex.org/I77079311"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hwan-Suck Chung","raw_affiliation_strings":["Department of Oriental Pharmacy, College of Pharmacy, VCRC of Wonkwang University","Department of Pharmacology, College of Oriental Medicine, Kyung Hee University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oriental Pharmacy, College of Pharmacy, VCRC of Wonkwang University","institution_ids":["https://openalex.org/I77079311"]},{"raw_affiliation_string":"Department of Pharmacology, College of Oriental Medicine, Kyung Hee University","institution_ids":["https://openalex.org/I35928602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010258407","display_name":"Hyo\u2010Jin An","orcid":"https://orcid.org/0000-0002-2937-874X","observed_orcids":["https://orcid.org/0000-0002-2937-874X"]},"institutions":[{"id":"https://openalex.org/I35928602","display_name":"Kyung Hee University","ror":"https://ror.org/01zqcg218","country_code":"KR","type":"education","lineage":["https://openalex.org/I35928602"]},{"id":"https://openalex.org/I77079311","display_name":"Wonkwang University","ror":"https://ror.org/006776986","country_code":"KR","type":"education","lineage":["https://openalex.org/I77079311"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyo-Jin An","raw_affiliation_strings":["Department of Oriental Pharmacy, College of Pharmacy, VCRC of Wonkwang University","Department of Pharmacology, College of Oriental Medicine, Kyung Hee University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oriental Pharmacy, College of Pharmacy, VCRC of Wonkwang University","institution_ids":["https://openalex.org/I77079311"]},{"raw_affiliation_string":"Department of Pharmacology, College of Oriental Medicine, Kyung Hee University","institution_ids":["https://openalex.org/I35928602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060425593","display_name":"Sang-Wan Seo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I35928602","display_name":"Kyung Hee University","ror":"https://ror.org/01zqcg218","country_code":"KR","type":"education","lineage":["https://openalex.org/I35928602"]},{"id":"https://openalex.org/I77079311","display_name":"Wonkwang University","ror":"https://ror.org/006776986","country_code":"KR","type":"education","lineage":["https://openalex.org/I77079311"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sang-Wan Seo","raw_affiliation_strings":["Department of Oriental Pharmacy, College of Pharmacy, VCRC of Wonkwang University","Department of Pharmacology, College of Oriental Medicine, Kyung Hee University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oriental Pharmacy, College of Pharmacy, VCRC of Wonkwang University","institution_ids":["https://openalex.org/I77079311"]},{"raw_affiliation_string":"Department of Pharmacology, College of Oriental Medicine, Kyung Hee University","institution_ids":["https://openalex.org/I35928602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100648626","display_name":"Tae\u2010Gyun Kim","orcid":"https://orcid.org/0000-0002-2116-4579","observed_orcids":["https://orcid.org/0000-0002-2116-4579","https://orcid.org/0000-0002-6867-0487"]},"institutions":[{"id":"https://openalex.org/I77079311","display_name":"Wonkwang University","ror":"https://ror.org/006776986","country_code":"KR","type":"education","lineage":["https://openalex.org/I77079311"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Tae-gyun Kim","raw_affiliation_strings":["College of Oriental Medicine, Wonkwang University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Oriental Medicine, Wonkwang University","institution_ids":["https://openalex.org/I77079311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111665027","display_name":"Jin\u2010Hee Won","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I77079311","display_name":"Wonkwang University","ror":"https://ror.org/006776986","country_code":"KR","type":"education","lineage":["https://openalex.org/I77079311"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jin-Hee Won","raw_affiliation_strings":["College of Oriental Medicine, Wonkwang University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Oriental Medicine, Wonkwang University","institution_ids":["https://openalex.org/I77079311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113585498","display_name":"Jo\u2010Young Shin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I77079311","display_name":"Wonkwang University","ror":"https://ror.org/006776986","country_code":"KR","type":"education","lineage":["https://openalex.org/I77079311"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jo-Young Shin","raw_affiliation_strings":["College of Oriental Medicine, Wonkwang University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Oriental Medicine, Wonkwang University","institution_ids":["https://openalex.org/I77079311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100904841","display_name":"Kyoo-Seok Ahn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I35928602","display_name":"Kyung Hee University","ror":"https://ror.org/01zqcg218","country_code":"KR","type":"education","lineage":["https://openalex.org/I35928602"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyoo-Seok Ahn","raw_affiliation_strings":["Department of Pathology, College of Oriental Medicine, Kyung Hee University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, College of Oriental Medicine, Kyung Hee University","institution_ids":["https://openalex.org/I35928602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100695853","display_name":"Hyung\u2010Min Kim","orcid":"https://orcid.org/0000-0002-1712-2464","observed_orcids":["https://orcid.org/0000-0002-1712-2464"]},"institutions":[{"id":"https://openalex.org/I35928602","display_name":"Kyung Hee University","ror":"https://ror.org/01zqcg218","country_code":"KR","type":"education","lineage":["https://openalex.org/I35928602"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyung-Min Kim","raw_affiliation_strings":["Department of Pharmacology, College of Oriental Medicine, Kyung Hee University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, College of Oriental Medicine, Kyung Hee University","institution_ids":["https://openalex.org/I35928602"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.1399,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.93085393,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"27","issue":"1","first_page":"29","last_page":"33"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13919","display_name":"Medicinal plant effects and applications","score":0.4043000042438507,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13919","display_name":"Medicinal plant effects and applications","score":0.4043000042438507,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.13729999959468842,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.0843999981880188,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herbal-medicine","display_name":"herbal medicine","score":0.8479999899864197},{"id":"https://openalex.org/keywords/immune-enhancement","display_name":"immune enhancement","score":0.9459999799728394},{"id":"https://openalex.org/keywords/cytokine-production","display_name":"cytokine production","score":0.9599999785423279},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.9610000252723694},{"id":"https://openalex.org/keywords/il-4","display_name":"IL-4","score":1.0},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.9729999899864197},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9430000185966492},{"id":"https://openalex.org/keywords/il-12","display_name":"IL-12","score":0.9739999771118164},{"id":"https://openalex.org/keywords/molt-4-cells","display_name":"MOLT-4 cells","score":0.8529999852180481},{"id":"https://openalex.org/keywords/peritoneal-macrophages","display_name":"peritoneal macrophages","score":0.8889999985694885},{"id":"https://openalex.org/keywords/splenocytes","display_name":"splenocytes","score":0.8579999804496765},{"id":"https://openalex.org/keywords/herbal-combination","display_name":"herbal combination","score":0.3440000116825104}],"concepts":[{"id":"https://openalex.org/C189976730","wikidata":"https://www.wikidata.org/wiki/Q3493700","display_name":"Splenocyte","level":3,"score":0.7361282110214233},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6772952079772949},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.6490224599838257},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6089091300964355},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.5210763216018677},{"id":"https://openalex.org/C74172505","wikidata":"https://www.wikidata.org/wiki/Q194908","display_name":"Interleukin","level":3,"score":0.4670723080635071},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4539225101470947},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4293524920940399},{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.41989070177078247},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4086844027042389},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.36522430181503296}],"mesh":[{"descriptor_ui":"D000276","descriptor_name":"Adjuvants, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004365","descriptor_name":"Drugs, Chinese Herbal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007202","descriptor_name":"Indicators and Reagents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D017737","descriptor_name":"Macrophages, Peritoneal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017737","descriptor_name":"Macrophages, Peritoneal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1248/bpb.27.29","doi":"https://doi.org/10.1248/bpb.27.29","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.27.29","pdf_url":"https://www.jstage.jst.go.jp/article/bpb/27/1/27_1_29/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},{"id":"pmid:14709894","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14709894","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological & pharmaceutical bulletin","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1248/bpb.27.29","doi":"https://doi.org/10.1248/bpb.27.29","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.27.29","pdf_url":"https://www.jstage.jst.go.jp/article/bpb/27/1/27_1_29/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321310","display_name":"Wonkwang University","ror":"https://ror.org/006776986"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1999428692.pdf","grobid_xml":"https://content.openalex.org/works/W1999428692.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W11967522","https://openalex.org/W59062641","https://openalex.org/W1509810344","https://openalex.org/W1658684323","https://openalex.org/W1968095991","https://openalex.org/W1985347943","https://openalex.org/W1990197546","https://openalex.org/W1997283322","https://openalex.org/W2020977425","https://openalex.org/W2030261077","https://openalex.org/W2034312189","https://openalex.org/W2055136480","https://openalex.org/W2063231487","https://openalex.org/W2073879459","https://openalex.org/W2082652706","https://openalex.org/W2083549635","https://openalex.org/W2085962294","https://openalex.org/W2095127706","https://openalex.org/W2095286887","https://openalex.org/W2095351296","https://openalex.org/W2117768107","https://openalex.org/W2118205675","https://openalex.org/W2143998634","https://openalex.org/W2145742439","https://openalex.org/W2160063406","https://openalex.org/W2162549351","https://openalex.org/W2167078690","https://openalex.org/W2172466148","https://openalex.org/W2412498925","https://openalex.org/W2413275172","https://openalex.org/W4230553020","https://openalex.org/W4251511981"],"related_works":["https://openalex.org/W2125834134","https://openalex.org/W2019102617","https://openalex.org/W2051111573","https://openalex.org/W7100943803","https://openalex.org/W2040161897","https://openalex.org/W2132452439","https://openalex.org/W2163663352","https://openalex.org/W2126301788","https://openalex.org/W2144228090","https://openalex.org/W4392712341"],"abstract_inverted_index":{"The":[0],"herbal":[1],"formulation":[2],"Bouum-Myunyuk-Dan":[3],"(BMD)":[4],"has":[5,13],"long":[6],"been":[7,14],"used":[8],"for":[9,92,96,127,134,157,161],"various":[10,180],"diseases.":[11],"It":[12],"shown":[15],"to":[16],"have":[17,172],"antimicrobial":[18],"and":[19,59,72,77,83,94,129,131,149,159],"anti":[20],"viral":[21],"activity":[22],"clinically.":[23],"However,":[24],"it":[25],"is":[26],"still":[27],"unclear":[28],"how":[29],"BMD":[30,45,67,102,123,138,170],"exerts":[31],"these":[32,166],"effects":[33],"in":[34,51,60,151],"experimental":[35],"models.":[36],"In":[37,136,164],"this":[38],"study,":[39],"we":[40],"investigated":[41],"the":[42,47,70,104,142,177],"effect":[43,175],"of":[44,49,74,122,144,179],"on":[46],"production":[48,85,107,143,178],"cytokines":[50],"a":[52,65],"human":[53],"T":[54],"cell":[55],"line,":[56],"MOLT-4":[57],"cells,":[58],"mouse":[61,152],"peritoneal":[62,153],"macrophages.":[63],"As":[64],"result,":[66],"significantly":[68,79],"increased":[69,80,103,141],"viability":[71],"proliferation":[73],"splenocytes":[75],"(p<0.05)":[76],"also":[78],"interleukin":[81],"(IL)-2":[82],"IL-4":[84,130],"compared":[86,116],"with":[87,117],"media":[88],"control":[89],"(about":[90],"2.7-fold":[91,156],"IL-2":[93,128],"6.7-fold":[95],"IL-4,":[97],"p<0.05)":[98],"after":[99],"24":[100],"h.":[101],"interferon":[105],"(IFN)-gamma":[106],"by":[108],"3.7-fold":[109],"but":[110],"there":[111],"were":[112,124],"no":[113],"significant":[114],"differences":[115],"controls.":[118],"Maximal":[119],"effective":[120],"concentrations":[121],"1":[125],"mg/ml":[126,133],"0.1":[132],"IFN-gamma.":[135],"addition,":[137],"(0.01":[139],"mg/ml)":[140],"tumor":[145],"necrosis":[146],"factor":[147],"(TNF)-alpha":[148],"IL-12":[150],"macrophages":[154],"(by":[155],"TNF-alpha":[158],"42.5-fold":[160],"IL-12,":[162],"p<0.05).":[163],"conclusion,":[165],"data":[167],"indicate":[168],"that":[169],"may":[171],"an":[173],"immune-enhancing":[174],"through":[176],"cytokines.":[181]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}