{"id":"https://openalex.org/W1999014245","doi":"https://doi.org/10.1016/j.bone.2004.09.016","title":"Effect of simulated weightlessness on osteoprogenitor cell number and proliferation in young and adult rats","display_name":"Effect of simulated weightlessness on osteoprogenitor cell number and proliferation in young and adult rats","publication_year":2004,"publication_date":"2004-12-06","ids":{"openalex":"https://openalex.org/W1999014245","doi":"https://doi.org/10.1016/j.bone.2004.09.016","mag":"1999014245","pmid":"https://pubmed.ncbi.nlm.nih.gov/15664015"},"language":"en","primary_location":{"id":"doi:10.1016/j.bone.2004.09.016","doi":"https://doi.org/10.1016/j.bone.2004.09.016","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bone.2004.09.016","pdf_url":null,"source":{"id":"https://openalex.org/S121725775","display_name":"Bone","issn_l":"1873-2763","issn":["1873-2763","8756-3282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058853482","display_name":"N Basso","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"N. Basso","raw_affiliation_strings":["Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada M5G 1G6. nick.basso@utoronto.ca","Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada M5G 1G6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada M5G 1G6. nick.basso@utoronto.ca","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada M5G 1G6","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110192895","display_name":"C.G. Bellows","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"C.G. Bellows","raw_affiliation_strings":["Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada M5G 1G6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada M5G 1G6","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110418149","display_name":"J. N. M. Heersche","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"J.N.M. Heersche","raw_affiliation_strings":["Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada M5G 1G6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada M5G 1G6","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5058853482"],"corresponding_institution_ids":["https://openalex.org/I185261750"],"apc_list":{"value":3960,"currency":"USD","value_usd":3960},"apc_paid":null,"fwci":2.0573,"has_fulltext":false,"cited_by_count":54,"citation_normalized_percentile":{"value":0.85030886,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"36","issue":"1","first_page":"173","last_page":"183"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/simulated-microgravity","display_name":"simulated microgravity","score":0.9020000100135803},{"id":"https://openalex.org/keywords/hindlimb-unloading","display_name":"hindlimb unloading","score":0.9390000104904175},{"id":"https://openalex.org/keywords/osteoprogenitor-cells","display_name":"osteoprogenitor cells","score":0.9419999718666077},{"id":"https://openalex.org/keywords/osteoblast-surface","display_name":"osteoblast surface","score":0.5740000009536743},{"id":"https://openalex.org/keywords/bone-loss","display_name":"bone loss","score":0.7799999713897705},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.4779999852180481},{"id":"https://openalex.org/keywords/osteoblast-proliferation","display_name":"osteoblast proliferation","score":0.7049999833106995},{"id":"https://openalex.org/keywords/trabecular-bone-microarchitecture","display_name":"trabecular bone microarchitecture","score":0.6539999842643738},{"id":"https://openalex.org/keywords/osteoclasts","display_name":"osteoclasts","score":0.6549999713897705},{"id":"https://openalex.org/keywords/proximal-tibial-metaphysis","display_name":"proximal tibial metaphysis","score":0.7789999842643738},{"id":"https://openalex.org/keywords/proximal-femur","display_name":"proximal femur","score":0.6819999814033508},{"id":"https://openalex.org/keywords/proximal-humerus","display_name":"proximal humerus","score":0.9120000004768372},{"id":"https://openalex.org/keywords/spaceflight-bone-loss","display_name":"spaceflight bone loss","score":0.7039999961853027}],"concepts":[{"id":"https://openalex.org/C2778260815","wikidata":"https://www.wikidata.org/wiki/Q917177","display_name":"Osteoblast","level":3,"score":0.7598901987075806},{"id":"https://openalex.org/C2776350087","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cancellous bone","level":2,"score":0.6516358852386475},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.6127197742462158},{"id":"https://openalex.org/C2780554211","wikidata":"https://www.wikidata.org/wiki/Q176503","display_name":"Femur","level":2,"score":0.5594200491905212},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5267062783241272},{"id":"https://openalex.org/C2781451080","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cortical bone","level":2,"score":0.5020973682403564},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.47933945059776306},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.467489629983902},{"id":"https://openalex.org/C160160445","wikidata":"https://www.wikidata.org/wiki/Q24769688","display_name":"Alkaline phosphatase","level":3,"score":0.4588625431060791},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3838014602661133},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.376160204410553},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.34481802582740784},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.23270413279533386},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.19492140412330627},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.12356069684028625},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.09382706880569458},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010006","descriptor_name":"Osteoblasts","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D014893","descriptor_name":"Weightlessness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019417","descriptor_name":"Hindlimb Suspension","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.bone.2004.09.016","doi":"https://doi.org/10.1016/j.bone.2004.09.016","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bone.2004.09.016","pdf_url":null,"source":{"id":"https://openalex.org/S121725775","display_name":"Bone","issn_l":"1873-2763","issn":["1873-2763","8756-3282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone","raw_type":"journal-article"},{"id":"pmid:15664015","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15664015","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334436","display_name":"Canadian Space Agency","ror":"https://ror.org/03a1gte98"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W114377542","https://openalex.org/W118347698","https://openalex.org/W198503490","https://openalex.org/W1495603145","https://openalex.org/W1570147293","https://openalex.org/W1718909266","https://openalex.org/W1884487838","https://openalex.org/W1931179318","https://openalex.org/W1970035913","https://openalex.org/W1979529284","https://openalex.org/W1986276800","https://openalex.org/W1994976244","https://openalex.org/W1998886278","https://openalex.org/W2000231768","https://openalex.org/W2020616952","https://openalex.org/W2023931976","https://openalex.org/W2024828272","https://openalex.org/W2035565165","https://openalex.org/W2037133888","https://openalex.org/W2037156220","https://openalex.org/W2047656173","https://openalex.org/W2049945531","https://openalex.org/W2055690022","https://openalex.org/W2073130464","https://openalex.org/W2075375954","https://openalex.org/W2088737765","https://openalex.org/W2091643005","https://openalex.org/W2091679560","https://openalex.org/W2110802982","https://openalex.org/W2113565126","https://openalex.org/W2124169310","https://openalex.org/W2127905508","https://openalex.org/W2129749863","https://openalex.org/W2149555496","https://openalex.org/W2188575522","https://openalex.org/W2188859325","https://openalex.org/W2231105542","https://openalex.org/W2264374290","https://openalex.org/W2340257712","https://openalex.org/W2400294607","https://openalex.org/W2408993738","https://openalex.org/W6712876880"],"related_works":["https://openalex.org/W2161050088","https://openalex.org/W2014949982","https://openalex.org/W4408567160","https://openalex.org/W2386252809","https://openalex.org/W281945896","https://openalex.org/W1884487838","https://openalex.org/W2037156220","https://openalex.org/W1759177456","https://openalex.org/W1888774673","https://openalex.org/W2093454481"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}