{"id":"https://openalex.org/W1998978047","doi":"https://doi.org/10.1007/s10517-006-0361-3","title":"Effect of long-term mental and pain stress on the dynamics of H4 histone acetylation in hippocampal neurons of rats with different levels of nervous system excitability","display_name":"Effect of long-term mental and pain stress on the dynamics of H4 histone acetylation in hippocampal neurons of rats with different levels of nervous system excitability","publication_year":2006,"publication_date":"2006-09-01","ids":{"openalex":"https://openalex.org/W1998978047","doi":"https://doi.org/10.1007/s10517-006-0361-3","mag":"1998978047","pmid":"https://pubmed.ncbi.nlm.nih.gov/17426844"},"language":"en","primary_location":{"id":"doi:10.1007/s10517-006-0361-3","doi":"https://doi.org/10.1007/s10517-006-0361-3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10517-006-0361-3","pdf_url":null,"source":{"id":"https://openalex.org/S141734485","display_name":"Bulletin of Experimental Biology and Medicine","issn_l":"0007-4888","issn":["0007-4888","0365-9615","1573-8221","2413-1008"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-1","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of Experimental Biology and Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"N. E. Sokolova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210112287","display_name":"Pavlov Institute of Physiology of the Russian Academy of Sciences","ror":"https://ror.org/022rrvm68","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210112287","https://openalex.org/I4210115279"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"N. E. Sokolova","raw_affiliation_strings":["Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg. shiryaeva@kolt.infran.ru","Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg. shiryaeva@kolt.infran.ru","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210112287"]},{"raw_affiliation_string":"Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210112287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112408235","display_name":"N. V. Shiryaeva","orcid":"https://orcid.org/0000-0001-9940-9575","observed_orcids":["https://orcid.org/0000-0001-9940-9575"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210112287","display_name":"Pavlov Institute of Physiology of the Russian Academy of Sciences","ror":"https://ror.org/022rrvm68","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210112287","https://openalex.org/I4210115279"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"N. V. Shiryaeva","raw_affiliation_strings":["Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210112287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063270046","display_name":"Natalia A. Dyuzhikova","orcid":"https://orcid.org/0000-0002-7550-118X","observed_orcids":["https://orcid.org/0000-0002-7550-118X","https://orcid.org/0000-0003-3617-5948"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210112287","display_name":"Pavlov Institute of Physiology of the Russian Academy of Sciences","ror":"https://ror.org/022rrvm68","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210112287","https://openalex.org/I4210115279"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"N. A. Dyuzhikova","raw_affiliation_strings":["Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210112287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001215282","display_name":"Yu. N. Savenko","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210112287","display_name":"Pavlov Institute of Physiology of the Russian Academy of Sciences","ror":"https://ror.org/022rrvm68","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210112287","https://openalex.org/I4210115279"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Yu. N. Savenko","raw_affiliation_strings":["Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210112287"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020496316","display_name":"Alexander I. Vaido","orcid":"https://orcid.org/0000-0002-6209-9902","observed_orcids":["https://orcid.org/0000-0002-6209-9902"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210112287","display_name":"Pavlov Institute of Physiology of the Russian Academy of Sciences","ror":"https://ror.org/022rrvm68","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210112287","https://openalex.org/I4210115279"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"A. I. Vaido","raw_affiliation_strings":["Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Genetics of Higher Nervous Activity, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210112287"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5112408235"],"corresponding_institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210112287"],"apc_list":null,"apc_paid":null,"fwci":0.1309,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.41494083,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"142","issue":"3","first_page":"341","last_page":"343"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.326200008392334,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.326200008392334,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.2549000084400177,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10242","display_name":"Posttraumatic Stress Disorder Research","score":0.12349999696016312,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-stress","display_name":"chronic stress","score":0.5070000290870667},{"id":"https://openalex.org/keywords/pain-stress","display_name":"pain stress","score":0.8489999771118164},{"id":"https://openalex.org/keywords/psychological-stress","display_name":"psychological stress","score":0.8859999775886536},{"id":"https://openalex.org/keywords/hippocampal-ca3","display_name":"hippocampal CA3","score":0.8650000095367432},{"id":"https://openalex.org/keywords/pyramidal-neurons","display_name":"pyramidal neurons","score":0.9869999885559082},{"id":"https://openalex.org/keywords/nervous-system-excitability","display_name":"nervous system excitability","score":0.9010000228881836},{"id":"https://openalex.org/keywords/posttraumatic-stress-disorder","display_name":"post-traumatic stress disorder","score":0.7900000214576721},{"id":"https://openalex.org/keywords/psychogenic-disorders","display_name":"psychogenic disorders","score":0.6290000081062317},{"id":"https://openalex.org/keywords/genome-expression","display_name":"genome expression","score":0.5040000081062317},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.5899999737739563}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7278252840042114},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.7268925309181213},{"id":"https://openalex.org/C119157956","wikidata":"https://www.wikidata.org/wiki/Q796604","display_name":"Acetylation","level":3,"score":0.7204546928405762},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.7029243111610413},{"id":"https://openalex.org/C2779085176","wikidata":"https://www.wikidata.org/wiki/Q24721644","display_name":"Histone H4","level":4,"score":0.666420042514801},{"id":"https://openalex.org/C545706735","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Nervous system","level":2,"score":0.42209330201148987},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4063276946544647},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3963061273097992},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20189297199249268},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13981011509895325}],"mesh":[{"descriptor_ui":"D000107","descriptor_name":"Acetylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013315","descriptor_name":"Stress, Psychological","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10517-006-0361-3","doi":"https://doi.org/10.1007/s10517-006-0361-3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10517-006-0361-3","pdf_url":null,"source":{"id":"https://openalex.org/S141734485","display_name":"Bulletin of Experimental Biology and Medicine","issn_l":"0007-4888","issn":["0007-4888","0365-9615","1573-8221","2413-1008"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-1","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of Experimental Biology and Medicine","raw_type":"journal-article"},{"id":"pmid:17426844","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17426844","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of experimental biology and medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":3,"referenced_works":["https://openalex.org/W1996978236","https://openalex.org/W2079029980","https://openalex.org/W6606673370"],"related_works":["https://openalex.org/W2046567213","https://openalex.org/W2751042514","https://openalex.org/W2027578106","https://openalex.org/W3158341763","https://openalex.org/W2071536142","https://openalex.org/W2076512079","https://openalex.org/W1968518039","https://openalex.org/W4293200599","https://openalex.org/W2102812580","https://openalex.org/W1972943884"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}