{"id":"https://openalex.org/W1998970318","doi":"https://doi.org/10.1007/s11095-009-9970-7","title":"Evaluation of Drug-Polymer Miscibility in Amorphous Solid Dispersion Systems","display_name":"Evaluation of Drug-Polymer Miscibility in Amorphous Solid Dispersion Systems","publication_year":2009,"publication_date":"2009-09-21","ids":{"openalex":"https://openalex.org/W1998970318","doi":"https://doi.org/10.1007/s11095-009-9970-7","mag":"1998970318","pmid":"https://pubmed.ncbi.nlm.nih.gov/19771495"},"language":"en","primary_location":{"id":"doi:10.1007/s11095-009-9970-7","doi":"https://doi.org/10.1007/s11095-009-9970-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11095-009-9970-7","pdf_url":null,"source":{"id":"https://openalex.org/S103865650","display_name":"Pharmaceutical Research","issn_l":"0724-8741","issn":["0724-8741","1573-904X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutical Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088719110","display_name":"Alfred C. F. Rumondor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alfred C. F. Rumondor","raw_affiliation_strings":["Department of Industrial and Physical Pharmacy, School of Pharmacy, Purdue University, West Lafayette, Indiana, 47907, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Industrial and Physical Pharmacy, School of Pharmacy, Purdue University, West Lafayette, Indiana, 47907, USA","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082443817","display_name":"Igor Ivanisevic","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Igor Ivanisevic","raw_affiliation_strings":["SSCI, a division of Aptuit Inc., West Lafayette, Indiana, 47906, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SSCI, a division of Aptuit Inc., West Lafayette, Indiana, 47906, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Simon Bates","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Simon Bates","raw_affiliation_strings":["SSCI, a division of Aptuit Inc., West Lafayette, Indiana, 47906, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SSCI, a division of Aptuit Inc., West Lafayette, Indiana, 47906, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049713684","display_name":"David E. Alonzo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David E. Alonzo","raw_affiliation_strings":["Department of Industrial and Physical Pharmacy, School of Pharmacy, Purdue University, West Lafayette, Indiana, 47907, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Industrial and Physical Pharmacy, School of Pharmacy, Purdue University, West Lafayette, Indiana, 47907, USA","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090835640","display_name":"Lynne S. Taylor","orcid":"https://orcid.org/0000-0002-4568-6021","observed_orcids":["https://orcid.org/0000-0002-4568-6021"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lynne S. Taylor","raw_affiliation_strings":["Department of Industrial and Physical Pharmacy, School of Pharmacy, Purdue University, West Lafayette, Indiana, 47907, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Industrial and Physical Pharmacy, School of Pharmacy, Purdue University, West Lafayette, Indiana, 47907, USA","institution_ids":["https://openalex.org/I219193219"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5090835640"],"corresponding_institution_ids":["https://openalex.org/I219193219"],"apc_list":{"value":4690,"currency":"USD","value_usd":4690},"apc_paid":null,"fwci":6.0967,"has_fulltext":false,"cited_by_count":194,"citation_normalized_percentile":{"value":0.97236982,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"26","issue":"11","first_page":"2523","last_page":"2534"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10389","display_name":"Polymer crystallization and properties","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11881","display_name":"Crystallization and Solubility Studies","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug-polymer-miscibility","display_name":"drug-polymer miscibility","score":0.9980000257492065},{"id":"https://openalex.org/keywords/amorphous-solid-dispersions","display_name":"amorphous solid dispersions","score":0.9860000014305115},{"id":"https://openalex.org/keywords/felodipine","display_name":"felodipine","score":0.9229999780654907},{"id":"https://openalex.org/keywords/nifedipine","display_name":"nifedipine","score":0.996999979019165},{"id":"https://openalex.org/keywords/ketoconazole","display_name":"ketoconazole","score":1.0},{"id":"https://openalex.org/keywords/polyvinylpyrrolidone","display_name":"polyvinylpyrrolidone","score":0.9869999885559082},{"id":"https://openalex.org/keywords/poly-acrylic-acid","display_name":"poly(acrylic acid)","score":0.996999979019165},{"id":"https://openalex.org/keywords/pair-distribution-function","display_name":"pair distribution function","score":0.5979999899864197},{"id":"https://openalex.org/keywords/principal-component-analysis","display_name":"principal component analysis","score":0.8460000157356262},{"id":"https://openalex.org/keywords/binary-mixtures","display_name":"binary mixtures","score":0.5559999942779541},{"id":"https://openalex.org/keywords/local-chemical-environment","display_name":"local chemical environment","score":0.4779999852180481}],"concepts":[{"id":"https://openalex.org/C110884469","wikidata":"https://www.wikidata.org/wiki/Q906367","display_name":"Miscibility","level":3,"score":0.8526413440704346},{"id":"https://openalex.org/C39519442","wikidata":"https://www.wikidata.org/wiki/Q904893","display_name":"Differential scanning calorimetry","level":2,"score":0.733196496963501},{"id":"https://openalex.org/C56052488","wikidata":"https://www.wikidata.org/wiki/Q103382","display_name":"Amorphous solid","level":2,"score":0.7065255045890808},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6595377326011658},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.6114019155502319},{"id":"https://openalex.org/C177562468","wikidata":"https://www.wikidata.org/wiki/Q182893","display_name":"Dispersion (optics)","level":2,"score":0.5603827834129333},{"id":"https://openalex.org/C187404810","wikidata":"https://www.wikidata.org/wiki/Q733193","display_name":"Polymer blend","level":4,"score":0.5222797393798828},{"id":"https://openalex.org/C153642686","wikidata":"https://www.wikidata.org/wiki/Q70906","display_name":"Infrared spectroscopy","level":2,"score":0.42793336510658264},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.41849592328071594},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.364515095949173},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.28122204542160034},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.27007806301116943},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.14474931359291077},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0641985833644867},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.05069756507873535},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.050211042165756226},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002152","descriptor_name":"Calorimetry, Differential Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002626","descriptor_name":"Chemistry, Pharmaceutical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003460","descriptor_name":"Crystallization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007654","descriptor_name":"Ketoconazole","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009543","descriptor_name":"Nifedipine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011208","descriptor_name":"Powders","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011760","descriptor_name":"Pyrrolidinones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012995","descriptor_name":"Solubility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014961","descriptor_name":"X-Ray Diffraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015736","descriptor_name":"Felodipine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11095-009-9970-7","doi":"https://doi.org/10.1007/s11095-009-9970-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11095-009-9970-7","pdf_url":null,"source":{"id":"https://openalex.org/S103865650","display_name":"Pharmaceutical Research","issn_l":"0724-8741","issn":["0724-8741","1573-904X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutical Research","raw_type":"journal-article"},{"id":"pmid:19771495","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19771495","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutical research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W53851219","https://openalex.org/W164496576","https://openalex.org/W252847268","https://openalex.org/W1210478381","https://openalex.org/W1495757309","https://openalex.org/W1558381338","https://openalex.org/W1590254871","https://openalex.org/W1967935934","https://openalex.org/W1970767638","https://openalex.org/W1985071287","https://openalex.org/W1989461604","https://openalex.org/W1989801989","https://openalex.org/W1992169027","https://openalex.org/W2006657575","https://openalex.org/W2009938495","https://openalex.org/W2012622548","https://openalex.org/W2014953279","https://openalex.org/W2024934556","https://openalex.org/W2029687056","https://openalex.org/W2037352792","https://openalex.org/W2044594845","https://openalex.org/W2049439891","https://openalex.org/W2051055753","https://openalex.org/W2057499160","https://openalex.org/W2059365736","https://openalex.org/W2072253461","https://openalex.org/W2073418881","https://openalex.org/W2075179133","https://openalex.org/W2077594374","https://openalex.org/W2078950386","https://openalex.org/W2079193883","https://openalex.org/W6959373427"],"related_works":["https://openalex.org/W301866731","https://openalex.org/W4386416854","https://openalex.org/W2267776945","https://openalex.org/W3111684966","https://openalex.org/W4323851576","https://openalex.org/W2528205605","https://openalex.org/W2024934556","https://openalex.org/W2544584945","https://openalex.org/W2036889536","https://openalex.org/W2467014326"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":14},{"year":2018,"cited_by_count":15},{"year":2017,"cited_by_count":17},{"year":2016,"cited_by_count":15},{"year":2015,"cited_by_count":22},{"year":2014,"cited_by_count":16},{"year":2013,"cited_by_count":13},{"year":2012,"cited_by_count":14}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}