{"id":"https://openalex.org/W1998969952","doi":"https://doi.org/10.1128/aac.00717-11","title":"Influence of Body Weight, Ethnicity, Oral Contraceptives, and Pregnancy on the Pharmacokinetics of Azithromycin in Women of Childbearing Age","display_name":"Influence of Body Weight, Ethnicity, Oral Contraceptives, and Pregnancy on the Pharmacokinetics of Azithromycin in Women of Childbearing Age","publication_year":2011,"publication_date":"2011-11-22","ids":{"openalex":"https://openalex.org/W1998969952","doi":"https://doi.org/10.1128/aac.00717-11","mag":"1998969952","pmid":"https://pubmed.ncbi.nlm.nih.gov/22106226","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3264225"},"language":"en","primary_location":{"id":"doi:10.1128/aac.00717-11","doi":"https://doi.org/10.1128/aac.00717-11","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aac.00717-11","pdf_url":null,"source":{"id":"https://openalex.org/S47215897","display_name":"Antimicrobial Agents and Chemotherapy","issn_l":"0066-4804","issn":["0066-4804","1070-6283","1098-6596"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Agents and Chemotherapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3264225","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043030502","display_name":"James H. Fischer","orcid":"https://orcid.org/0000-0001-5570-7562","observed_orcids":["https://orcid.org/0000-0001-5570-7562"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James H. Fischer","raw_affiliation_strings":["Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053051179","display_name":"Gloria E. Sarto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]},{"id":"https://openalex.org/I2801262154","display_name":"Meriter Hospital","ror":"https://ror.org/01w756144","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801262154","https://openalex.org/I2802661869"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gloria E. Sarto","raw_affiliation_strings":["Department of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin\u2014Madison, and University of Wisconsin Obstetrics Service, Meriter Hospital, Madison, Wisconsin, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin\u2014Madison, and University of Wisconsin Obstetrics Service, Meriter Hospital, Madison, Wisconsin, USA","institution_ids":["https://openalex.org/I135310074","https://openalex.org/I2801262154"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049150655","display_name":"Mitra Habibi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitra Habibi","raw_affiliation_strings":["Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","aDepartment of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"aDepartment of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036608680","display_name":"Sarah J. Kilpatrick","orcid":"https://orcid.org/0000-0001-8322-3709","observed_orcids":["https://orcid.org/0000-0001-8322-3709"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah J. Kilpatrick","raw_affiliation_strings":["Department of Obstetrics and Gynecology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA","cDepartment of Obstetrics and Gynecology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"cDepartment of Obstetrics and Gynecology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088481567","display_name":"RUTH E. TUOMALA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruth E. Tuomala","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Brigham & Women's Hospital, Harvard University School of Medicine, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Brigham & Women's Hospital, Harvard University School of Medicine, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087338950","display_name":"Janice M. Shier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I4210114445","display_name":"Michigan Medicine","ror":"https://ror.org/01zcpa714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janice M. Shier","raw_affiliation_strings":["Department of Obstetrics and Gynecology, College of Medicine, University of Michigan, Ann Arbor, Michigan, USA","eDepartment of Obstetrics and Gynecology, College of Medicine, University of Michigan, Ann Arbor, Michigan, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, College of Medicine, University of Michigan, Ann Arbor, Michigan, USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"eDepartment of Obstetrics and Gynecology, College of Medicine, University of Michigan, Ann Arbor, Michigan, USA","institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4210114445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070237592","display_name":"Lori Wollet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lori Wollett","raw_affiliation_strings":["Office of Clinical Trials, University of Wisconsin\u2014Madison, and School of Medicine and Public Health, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Office of Clinical Trials, University of Wisconsin\u2014Madison, and School of Medicine and Public Health, University of Wisconsin\u2014Madison, Madison, Wisconsin, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Patricia A. Fischer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patricia A. Fischer","raw_affiliation_strings":["Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","aDepartment of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"aDepartment of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057514879","display_name":"Kinnari S. Khorana","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kinnari S. Khorana","raw_affiliation_strings":["Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","aDepartment of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"aDepartment of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055269054","display_name":"Keith A. Rodvold","orcid":"https://orcid.org/0000-0002-7200-7346","observed_orcids":["https://orcid.org/0000-0002-7200-7346"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Keith A. Rodvold","raw_affiliation_strings":["Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","aDepartment of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]},{"raw_affiliation_string":"aDepartment of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.3358,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.77296965,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"56","issue":"2","first_page":"715","last_page":"724"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.026200000196695328,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/azithromycin","display_name":"azithromycin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.9850000143051147},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.9950000047683716},{"id":"https://openalex.org/keywords/women-of-reproductive-age","display_name":"women of reproductive age","score":0.8090000152587891},{"id":"https://openalex.org/keywords/oral-contraceptives","display_name":"oral contraceptives","score":0.9800000190734863},{"id":"https://openalex.org/keywords/ethnicity","display_name":"ethnicity","score":0.6240000128746033},{"id":"https://openalex.org/keywords/lean-body-weight","display_name":"lean body weight","score":0.8930000066757202},{"id":"https://openalex.org/keywords/african-american-women","display_name":"African American women","score":0.6620000004768372},{"id":"https://openalex.org/keywords/oral-clearance","display_name":"oral clearance","score":0.7670000195503235},{"id":"https://openalex.org/keywords/sparse-sampling","display_name":"sparse sampling","score":0.5989999771118164},{"id":"https://openalex.org/keywords/dose-adjustment","display_name":"dose adjustment","score":0.6449999809265137},{"id":"https://openalex.org/keywords/prenatal-drug-exposure","display_name":"prenatal drug exposure","score":0.699999988079071},{"id":"https://openalex.org/keywords/three-compartment-model","display_name":"three-compartment model","score":0.6890000104904175}],"concepts":[{"id":"https://openalex.org/C2778907293","wikidata":"https://www.wikidata.org/wiki/Q165399","display_name":"Azithromycin","level":3,"score":0.9171396493911743},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8158142566680908},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6684868335723877},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.6140825748443604},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.5809724926948547},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.5288713574409485},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.4614194333553314},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3473980724811554},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.32227206230163574},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.249559223651886},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.10236179828643799},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06103795766830444},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003276","descriptor_name":"Contraceptives, Oral","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003276","descriptor_name":"Contraceptives, Oral","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005006","descriptor_name":"Ethnicity","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017963","descriptor_name":"Azithromycin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D017963","descriptor_name":"Azithromycin","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D019540","descriptor_name":"Area Under Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/aac.00717-11","doi":"https://doi.org/10.1128/aac.00717-11","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aac.00717-11","pdf_url":null,"source":{"id":"https://openalex.org/S47215897","display_name":"Antimicrobial Agents and Chemotherapy","issn_l":"0066-4804","issn":["0066-4804","1070-6283","1098-6596"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Agents and Chemotherapy","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3264225","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3264225","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrob Agents Chemother","raw_type":"Text"},{"id":"pmid:22106226","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22106226","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial agents and chemotherapy","raw_type":"Clinical Trial"},{"id":"pmh:oai:figshare.com:article/10777016","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Influence_of_Body_Weight_Ethnicity_Oral_Contraceptives_and_Pregnancy_on_the_Pharmacokinetics_of_Azithromycin_in_Women_of_Child-Bearing_Age/10777016","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3264225","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3264225","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrob Agents Chemother","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G3081102558","display_name":"GENERAL CLINICAL RESEARCH CENTER","funder_award_id":"M01RR013987","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320309434","display_name":"University of Wisconsin-Madison","ror":"https://ror.org/01y2jtd41"},{"id":"https://openalex.org/F4320313443","display_name":"National Jewish Health","ror":"https://ror.org/016z2bp30"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1550111394","https://openalex.org/W1573668492","https://openalex.org/W1840586683","https://openalex.org/W1898270805","https://openalex.org/W1964763802","https://openalex.org/W1966309480","https://openalex.org/W1974148310","https://openalex.org/W1974759427","https://openalex.org/W1975018822","https://openalex.org/W1975223621","https://openalex.org/W1989525615","https://openalex.org/W1989867753","https://openalex.org/W1991250143","https://openalex.org/W1999449749","https://openalex.org/W2005815716","https://openalex.org/W2006078265","https://openalex.org/W2007256359","https://openalex.org/W2007603900","https://openalex.org/W2010568902","https://openalex.org/W2010684429","https://openalex.org/W2015221700","https://openalex.org/W2016354947","https://openalex.org/W2031580730","https://openalex.org/W2031857827","https://openalex.org/W2049293958","https://openalex.org/W2050005887","https://openalex.org/W2055788409","https://openalex.org/W2056025136","https://openalex.org/W2069463518","https://openalex.org/W2077548148","https://openalex.org/W2078188718","https://openalex.org/W2080803945","https://openalex.org/W2081116257","https://openalex.org/W2082621291","https://openalex.org/W2092602264","https://openalex.org/W2101264978","https://openalex.org/W2102904779","https://openalex.org/W2103136643","https://openalex.org/W2109111348","https://openalex.org/W2135819835","https://openalex.org/W2138989950","https://openalex.org/W2143648287","https://openalex.org/W2144374479","https://openalex.org/W2150557024","https://openalex.org/W2150760368","https://openalex.org/W2153424989","https://openalex.org/W2155654137","https://openalex.org/W2159601567","https://openalex.org/W2161446377","https://openalex.org/W2165852564","https://openalex.org/W2168310137","https://openalex.org/W2169675402","https://openalex.org/W2246750959","https://openalex.org/W2408248274","https://openalex.org/W4244041297"],"related_works":["https://openalex.org/W4411980097","https://openalex.org/W4391483251","https://openalex.org/W2100879832","https://openalex.org/W6977794132","https://openalex.org/W2103136643","https://openalex.org/W7131240361","https://openalex.org/W1972448142","https://openalex.org/W2393944179","https://openalex.org/W2592895699","https://openalex.org/W2153665985"],"abstract_inverted_index":{"Women":[0],"of":[1,10,49,58,67,125,136,148,225,245],"childbearing":[2,59],"age":[3,48,60],"commonly":[4],"receive":[5],"azithromycin":[6,19,63,88,149,185,206,229,246],"for":[7,64,87,152],"the":[8,65,122,126,134,145,159,188,243],"treatment":[9,66],"community-acquired":[11],"infections,":[12],"including":[13],"during":[14,241,248],"pregnancy.":[15],"This":[16],"study":[17],"determined":[18],"pharmacokinetics":[20],"in":[21,194],"pregnant":[22,43,106,200,211],"and":[23,26,54,107,117,133,161,215,227],"nonpregnant":[24,56,109,173,216],"women":[25,44,57,79,174,197,214,217,240],"identified":[27,141],"covariates":[28,140],"contributing":[29],"to":[30,51,172,181,237],"pharmacokinetic":[31],"variability.":[32],"Plasma":[33,83],"samples":[34,84],"were":[35,80,85,95,139,169,199,208],"collected":[36],"by":[37,89,97],"using":[38],"a":[39,46,118,179],"sparse-sampling":[40],"strategy":[41],"from":[42,55,72],"at":[45],"gestational":[47],"12":[50,77],"40":[52],"weeks":[53],"receiving":[61,176,202,219],"oral":[62,137,146,153,177,203,220],"an":[68],"infection.":[69],"Pharmacokinetic":[70],"data":[71,94],"extensive":[73],"sampling":[74],"conducted":[75],"on":[76],"healthy":[78],"also":[81],"included.":[82],"assayed":[86],"high-performance":[90],"liquid":[91],"chromatography.":[92],"Population":[93],"analyzed":[96],"nonlinear":[98],"mixed-effects":[99],"modeling.":[100],"The":[101],"population":[102],"analysis":[103],"included":[104],"53":[105],"25":[108],"women.":[110],"A":[111],"three-compartment":[112],"model":[113],"with":[114],"first-order":[115],"absorption":[116],"lag":[119],"time":[120],"provided":[121],"best":[123],"fit":[124],"data.":[127],"Lean":[128],"body":[129],"weight,":[130],"pregnancy,":[131,242],"ethnicity,":[132],"coadministration":[135],"contraceptives":[138],"as":[142],"significantly":[143],"influencing":[144],"clearance":[147,157],"and,":[150],"except":[151],"contraceptive":[154],"use,":[155],"intercompartmental":[156],"between":[158,210],"central":[160],"second":[162],"peripheral":[163],"compartments.":[164],"No":[165],"other":[166],"covariate":[167],"relationships":[168],"identified.":[170],"Compared":[171],"not":[175,218],"contraceptives,":[178],"21%":[180],"42%":[182],"higher":[183,223],"dose-adjusted":[184],"area":[186],"under":[187],"plasma":[189],"concentration-time":[190],"curve":[191],"(AUC)":[192],"occurred":[193],"non-African":[195,238],"American":[196,213,239],"who":[198],"or":[201],"contraceptives.":[204,221],"Conversely,":[205],"AUCs":[207],"similar":[209],"African":[212],"Although":[222],"levels":[224],"maternal":[226],"fetal":[228],"exposure":[230],"suggest":[231],"that":[232],"lower":[233],"doses":[234],"be":[235],"administered":[236],"consideration":[244],"pharmacodynamics":[247],"pregnancy":[249],"should":[250],"guide":[251],"any":[252],"dose":[253],"adjustments.":[254]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}