{"id":"https://openalex.org/W1998901690","doi":"https://doi.org/10.1001/jama.2012.29","title":"Caregiving Burden, Stress, and Health Effects Among Family Caregivers of Adult Cancer Patients","display_name":"Caregiving Burden, Stress, and Health Effects Among Family Caregivers of Adult Cancer Patients","publication_year":2012,"publication_date":"2012-01-24","ids":{"openalex":"https://openalex.org/W1998901690","doi":"https://doi.org/10.1001/jama.2012.29","mag":"1998901690","pmid":"https://pubmed.ncbi.nlm.nih.gov/22274687","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3304539"},"language":"en","primary_location":{"id":"doi:10.1001/jama.2012.29","doi":"https://doi.org/10.1001/jama.2012.29","is_oa":false,"landing_page_url":"https://doi.org/10.1001/jama.2012.29","pdf_url":null,"source":{"id":"https://openalex.org/S172573765","display_name":"JAMA","issn_l":"0002-9955","issn":["0002-9955","0098-7484","1538-3598","2376-8118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3304539","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054011041","display_name":"Margaret F. Bevans","orcid":"https://orcid.org/0000-0003-0448-2011","observed_orcids":["https://orcid.org/0000-0003-0448-2011"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I35344726","display_name":"United States Public Health Service","ror":"https://ror.org/05xf94514","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I35344726"]},{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margaret Bevans","raw_affiliation_strings":["US Public Health Service, Nursing Research & Translational Science, Nursing & Patient Care Services, Health Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA. mbevans@cc.nih.gov","US Public Health Service, Nursing Research & Translational Science, Nursing & Patient Care Services, Health Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"US Public Health Service, Nursing Research & Translational Science, Nursing & Patient Care Services, Health Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA. mbevans@cc.nih.gov","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210155647"]},{"raw_affiliation_string":"US Public Health Service, Nursing Research & Translational Science, Nursing & Patient Care Services, Health Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I35344726","https://openalex.org/I4210155647"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111764619","display_name":"Esther M. Sternberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Esther M. Sternberg","raw_affiliation_strings":["National Institutes of Health, Clinical Center 10 Center Drive, Room 12s235b, MSC 1905 Bethesda, MD 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institutes of Health, Clinical Center 10 Center Drive, Room 12s235b, MSC 1905 Bethesda, MD 20892","institution_ids":["https://openalex.org/I4210155647"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":77.0769,"has_fulltext":false,"cited_by_count":656,"citation_normalized_percentile":{"value":0.99969549,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"307","issue":"4","first_page":"398","last_page":"403"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13111","display_name":"Nursing care and research","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2922","display_name":"Research and Theory"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13111","display_name":"Nursing care and research","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2922","display_name":"Research and Theory"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13574","display_name":"Family Support in Illness","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/caregiver-burden","display_name":"caregiver burden","score":0.7839999794960022},{"id":"https://openalex.org/keywords/family-caregivers","display_name":"family caregivers","score":0.9700000286102295},{"id":"https://openalex.org/keywords/chronic-stress","display_name":"chronic stress","score":0.6200000047683716},{"id":"https://openalex.org/keywords/acute-myeloid-leukemia","display_name":"acute myeloid leukemia","score":0.8600000143051147},{"id":"https://openalex.org/keywords/allogeneic-hematopoietic-stem-cell-transplantation","display_name":"allogeneic hematopoietic stem cell transplantation","score":0.9950000047683716},{"id":"https://openalex.org/keywords/informal-care","display_name":"informal care","score":0.675000011920929},{"id":"https://openalex.org/keywords/immune-dysregulation","display_name":"immune dysregulation","score":0.9340000152587891},{"id":"https://openalex.org/keywords/autonomic-dysfunction","display_name":"autonomic dysfunction","score":0.9819999933242798},{"id":"https://openalex.org/keywords/caregiver-interventions","display_name":"caregiver interventions","score":0.38499999046325684}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8868473768234253},{"id":"https://openalex.org/C125370674","wikidata":"https://www.wikidata.org/wiki/Q1527480","display_name":"Stressor","level":2,"score":0.7117180228233337},{"id":"https://openalex.org/C2776101926","wikidata":"https://www.wikidata.org/wiki/Q5038976","display_name":"Caregiver stress","level":4,"score":0.6690658926963806},{"id":"https://openalex.org/C2779878486","wikidata":"https://www.wikidata.org/wiki/Q25053589","display_name":"Caregiver burden","level":4,"score":0.6654700040817261},{"id":"https://openalex.org/C2778900529","wikidata":"https://www.wikidata.org/wiki/Q2827779","display_name":"Family caregivers","level":2,"score":0.5797942876815796},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.5792035460472107},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.42682337760925293},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.4185929298400879},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.31402653455734253},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3120386600494385},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006304","descriptor_name":"Health Status","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000451","qualifier_name":"nursing","is_major_topic":true},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013315","descriptor_name":"Stress, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015464","descriptor_name":"Leukemia, Myelogenous, Chronic, BCR-ABL Positive","qualifier_ui":"Q000451","qualifier_name":"nursing","is_major_topic":false},{"descriptor_ui":"D015464","descriptor_name":"Leukemia, Myelogenous, Chronic, BCR-ABL Positive","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D017028","descriptor_name":"Caregivers","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D017281","descriptor_name":"Cost of Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018380","descriptor_name":"Hematopoietic Stem Cell Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1001/jama.2012.29","doi":"https://doi.org/10.1001/jama.2012.29","is_oa":false,"landing_page_url":"https://doi.org/10.1001/jama.2012.29","pdf_url":null,"source":{"id":"https://openalex.org/S172573765","display_name":"JAMA","issn_l":"0002-9955","issn":["0002-9955","0098-7484","1538-3598","2376-8118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA","raw_type":"journal-article"},{"id":"pmid:22274687","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22274687","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:3304539","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3304539","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"JAMA","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3304539","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3304539","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"JAMA","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[{"id":"https://openalex.org/G4076655197","display_name":"Problem Solving in Transplant Patients and Caregivers","funder_award_id":"Z01CL001148","funder_id":"https://openalex.org/F4320337376","funder_display_name":"NIH Clinical Center"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337376","display_name":"NIH Clinical Center","ror":"https://ror.org/04vfsmv21"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W28539586","https://openalex.org/W1520207918","https://openalex.org/W1556323812","https://openalex.org/W1769754295","https://openalex.org/W1925171380","https://openalex.org/W1963629744","https://openalex.org/W1969040129","https://openalex.org/W1969583912","https://openalex.org/W1971494202","https://openalex.org/W1981001896","https://openalex.org/W1993687023","https://openalex.org/W2000445391","https://openalex.org/W2005229523","https://openalex.org/W2006590440","https://openalex.org/W2007940382","https://openalex.org/W2010817954","https://openalex.org/W2019130175","https://openalex.org/W2023912603","https://openalex.org/W2027066260","https://openalex.org/W2027365236","https://openalex.org/W2039116367","https://openalex.org/W2040435093","https://openalex.org/W2047218988","https://openalex.org/W2064271564","https://openalex.org/W2067949717","https://openalex.org/W2075228692","https://openalex.org/W2078432113","https://openalex.org/W2078826300","https://openalex.org/W2089134353","https://openalex.org/W2089370127","https://openalex.org/W2096578420","https://openalex.org/W2097529540","https://openalex.org/W2098472703","https://openalex.org/W2098489144","https://openalex.org/W2102223615","https://openalex.org/W2105194498","https://openalex.org/W2105587305","https://openalex.org/W2109288884","https://openalex.org/W2113140773","https://openalex.org/W2117236354","https://openalex.org/W2129524213","https://openalex.org/W2131433218","https://openalex.org/W2134304841","https://openalex.org/W2138871559","https://openalex.org/W2153994184","https://openalex.org/W2160517494","https://openalex.org/W2163230835","https://openalex.org/W2317998661","https://openalex.org/W2327530675","https://openalex.org/W3023285562"],"related_works":["https://openalex.org/W7131895119","https://openalex.org/W2610102049","https://openalex.org/W2170715319","https://openalex.org/W2938976544","https://openalex.org/W7161895934","https://openalex.org/W1571676417","https://openalex.org/W4405047815","https://openalex.org/W2334827560","https://openalex.org/W4408275527","https://openalex.org/W2276563411"],"abstract_inverted_index":{"Unlike":[0],"professional":[1],"caregivers":[2,40,105,165],"such":[3,143],"as":[4,35],"physicians":[5],"and":[6,28,39,46,53,79,90,98,114,129,133,145,159,172],"nurses,":[7],"informal":[8],"caregivers,":[9],"typically":[10],"family":[11],"members":[12],"or":[13],"friends,":[14],"provide":[15],"care":[16,144],"to":[17,148,174],"individuals":[18,141],"with":[19,109,140,179],"a":[20,36,63,153],"variety":[21],"of":[22,62,163,168],"conditions":[23],"including":[24],"advanced":[25],"age,":[26],"dementia,":[27],"cancer.":[29],"This":[30,150],"experience":[31,42,61,120],"is":[32,67,96],"commonly":[33],"perceived":[34],"chronic":[37],"stressor,":[38],"often":[41,107],"negative":[43,121,169],"psychological,":[44],"behavioral,":[45],"physiological":[47],"effects":[48],"on":[49],"their":[50,134],"daily":[51,139],"lives":[52],"health.":[54],"In":[55],"this":[56],"report,":[57],"we":[58],"describe":[59],"the":[60,68,93,161,176,180],"53-year-old":[64],"woman":[65],"who":[66,74],"sole":[69],"caregiver":[70],"for":[71],"her":[72],"husband,":[73],"has":[75],"acute":[76],"myelogenous":[77],"leukemia":[78],"was":[80],"undergoing":[81],"allogeneic":[82],"hematopoietic":[83],"stem":[84],"cell":[85],"transplantation.":[86],"During":[87],"his":[88],"intense":[89],"unpredictable":[91],"course,":[92],"caregiver's":[94],"burden":[95,158],"complex":[97],"complicated":[99],"by":[100,127],"multiple":[101,110],"competing":[102],"priorities.":[103],"Because":[104],"are":[106,137],"faced":[108],"concurrent":[111],"stressful":[112],"events":[113],"extended,":[115],"unrelenting":[116],"stress,":[117],"they":[118],"may":[119],"health":[122,170],"effects,":[123],"mediated":[124],"in":[125],"part":[126],"immune":[128],"autonomic":[130],"dysregulation.":[131],"Physicians":[132],"interdisciplinary":[135],"teams":[136],"presented":[138],"providing":[142],"have":[146],"opportunity":[147],"intervene.":[149],"report":[151],"describes":[152],"case":[154],"that":[155],"exemplifies":[156],"caregiving":[157,181],"discusses":[160],"importance":[162],"identifying":[164],"at":[166],"risk":[167],"outcomes":[171],"intervening":[173],"attenuate":[175],"stress":[177],"associated":[178],"experience.":[182]},"counts_by_year":[{"year":2026,"cited_by_count":44},{"year":2025,"cited_by_count":42},{"year":2024,"cited_by_count":29},{"year":2023,"cited_by_count":47},{"year":2022,"cited_by_count":43},{"year":2021,"cited_by_count":91},{"year":2020,"cited_by_count":75},{"year":2019,"cited_by_count":61},{"year":2018,"cited_by_count":35},{"year":2017,"cited_by_count":50},{"year":2016,"cited_by_count":37},{"year":2015,"cited_by_count":38},{"year":2014,"cited_by_count":26},{"year":2013,"cited_by_count":24},{"year":2012,"cited_by_count":13}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}