{"id":"https://openalex.org/W1998899866","doi":"https://doi.org/10.1002/jcb.240480308","title":"Expression of heat shock genes during differentiation of mammalian osteoblasts and promyelocytic leukemia cells","display_name":"Expression of heat shock genes during differentiation of mammalian osteoblasts and promyelocytic leukemia cells","publication_year":1992,"publication_date":"1992-03-01","ids":{"openalex":"https://openalex.org/W1998899866","doi":"https://doi.org/10.1002/jcb.240480308","mag":"1998899866","pmid":"https://pubmed.ncbi.nlm.nih.gov/1400614"},"language":"en","primary_location":{"id":"doi:10.1002/jcb.240480308","doi":"https://doi.org/10.1002/jcb.240480308","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jcb.240480308","pdf_url":null,"source":{"id":"https://openalex.org/S53807158","display_name":"Journal of Cellular Biochemistry","issn_l":"0730-2312","issn":["0730-2312","1097-4644"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006183298","display_name":"Abdul Rauf Shakoori","orcid":"https://orcid.org/0000-0002-3950-9870","observed_orcids":["https://orcid.org/0000-0002-3950-9870"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abdul Rauf Shakoori","raw_affiliation_strings":["Department of Cell Biology, University of Massachusetts Medical Center, Worcester 01655"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, University of Massachusetts Medical Center, Worcester 01655","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039399811","display_name":"Annette M. Oberdorf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Annette M. Oberdorf","raw_affiliation_strings":["Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01655"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01655","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073570923","display_name":"Thomas A. Owen","orcid":"https://orcid.org/0000-0002-4994-6759","observed_orcids":["https://orcid.org/0000-0002-4994-6759"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas A. Owen","raw_affiliation_strings":["Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01655"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01655","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109568293","display_name":"Lee A. Weber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I134113660","display_name":"University of Nevada, Reno","ror":"https://ror.org/01keh0577","country_code":"US","type":"education","lineage":["https://openalex.org/I134113660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lee A. Weber","raw_affiliation_strings":["Department of Biology, University of Nevada, Reno, Nevada 89557"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Nevada, Reno, Nevada 89557","institution_ids":["https://openalex.org/I134113660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109166903","display_name":"Eileen D. Hickey","orcid":"https://orcid.org/0000-0002-4868-630X","observed_orcids":["https://orcid.org/0000-0002-4868-630X"]},"institutions":[{"id":"https://openalex.org/I134113660","display_name":"University of Nevada, Reno","ror":"https://ror.org/01keh0577","country_code":"US","type":"education","lineage":["https://openalex.org/I134113660"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eileen Hickey","raw_affiliation_strings":["Department of Biology, University of Nevada, Reno, Nevada 89557"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Nevada, Reno, Nevada 89557","institution_ids":["https://openalex.org/I134113660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081119848","display_name":"Janet Lee Stein","orcid":"https://orcid.org/0000-0002-2474-6822","observed_orcids":["https://orcid.org/0000-0002-2474-6822"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janet L. Stein","raw_affiliation_strings":["Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01655"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01655","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031362021","display_name":"Jane B. Lian","orcid":"https://orcid.org/0000-0001-8683-9138","observed_orcids":["https://orcid.org/0000-0001-8683-9138"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jane B. Lian","raw_affiliation_strings":["Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01655"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01655","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103217263","display_name":"Gary S. Stein","orcid":"https://orcid.org/0000-0001-8762-5422","observed_orcids":["https://orcid.org/0000-0001-8762-5422"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary S. Stein","raw_affiliation_strings":["Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01655"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, University of Massachusetts Medical Center, Worcester, Massachusetts 01655","institution_ids":["https://openalex.org/I166722992"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5110,"currency":"USD","value_usd":5110},"apc_paid":null,"fwci":2.7937,"has_fulltext":false,"cited_by_count":145,"citation_normalized_percentile":{"value":0.91830244,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"48","issue":"3","first_page":"277","last_page":"287"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heat-shock-genes","display_name":"heat shock genes","score":0.8379999995231628},{"id":"https://openalex.org/keywords/osteogenic-differentiation","display_name":"osteogenic differentiation","score":0.8880000114440918},{"id":"https://openalex.org/keywords/hl-60-cells","display_name":"HL-60 cells","score":0.9340000152587891},{"id":"https://openalex.org/keywords/promyelocytic-leukemia-cells","display_name":"promyelocytic leukemia cells","score":0.8790000081062317},{"id":"https://openalex.org/keywords/hsp27","display_name":"HSP27","score":0.890999972820282},{"id":"https://openalex.org/keywords/hsp60","display_name":"HSP60","score":0.9940000176429749},{"id":"https://openalex.org/keywords/hsp70","display_name":"HSP70","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hsp90","display_name":"HSP90","score":0.7760000228881836},{"id":"https://openalex.org/keywords/mrna-expression","display_name":"mRNA expression","score":0.7319999933242798},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.968999981880188},{"id":"https://openalex.org/keywords/cell-differentiation","display_name":"cell differentiation","score":0.8050000071525574},{"id":"https://openalex.org/keywords/growth-regulation","display_name":"growth regulation","score":0.3880000114440918}],"concepts":[{"id":"https://openalex.org/C2779559962","wikidata":"https://www.wikidata.org/wiki/Q14905263","display_name":"Hsp27","level":5,"score":0.7349163889884949},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6302558779716492},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5740368366241455},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.5586138963699341},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.5487478971481323},{"id":"https://openalex.org/C205260736","wikidata":"https://www.wikidata.org/wiki/Q418939","display_name":"Heat shock protein","level":3,"score":0.5417502522468567},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5386998057365417},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4783869981765747},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.45862525701522827},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4520910680294037},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.43608540296554565},{"id":"https://openalex.org/C68991219","wikidata":"https://www.wikidata.org/wiki/Q419102","display_name":"Hsp70","level":4,"score":0.42592352628707886},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18870240449905396}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010006","descriptor_name":"Osteoblasts","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D010006","descriptor_name":"Osteoblasts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015152","descriptor_name":"Blotting, Northern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015473","descriptor_name":"Leukemia, Promyelocytic, Acute","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/jcb.240480308","doi":"https://doi.org/10.1002/jcb.240480308","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jcb.240480308","pdf_url":null,"source":{"id":"https://openalex.org/S53807158","display_name":"Journal of Cellular Biochemistry","issn_l":"0730-2312","issn":["0730-2312","1097-4644"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Biochemistry","raw_type":"journal-article"},{"id":"pmid:1400614","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1400614","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cellular biochemistry","raw_type":"Journal Article"},{"id":"pmh:oai:escholarship.umassmed.edu:stein-1109","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.umassmed.edu/stein/110","pdf_url":null,"source":{"id":"https://openalex.org/S7407064370","display_name":"eScholarship@UMassChan","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Stein, Stein, Lian, vanWijnen Lab Publications","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.428600013256073,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4172909306","display_name":"SYNTHESIS OF OSTEOCALCIN IN BONE","funder_award_id":"R01AR033920","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G460737641","display_name":"OSTEOCALCIN FUNCTION IN RESORPTION","funder_award_id":"R01AR035166","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G6723465385","display_name":"Control of Osteoblast Proliferation and Differentiation","funder_award_id":"R01AR039588","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320306182","display_name":"March of Dimes Foundation","ror":"https://ror.org/04bd5p711"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W218971763","https://openalex.org/W1488144878","https://openalex.org/W1503965672","https://openalex.org/W1505589424","https://openalex.org/W1531522492","https://openalex.org/W1569034312","https://openalex.org/W1589329776","https://openalex.org/W1596822567","https://openalex.org/W1600365637","https://openalex.org/W1821289342","https://openalex.org/W1885090803","https://openalex.org/W1893871256","https://openalex.org/W1935621669","https://openalex.org/W1947020037","https://openalex.org/W1964463861","https://openalex.org/W1973826266","https://openalex.org/W1976442979","https://openalex.org/W1977388184","https://openalex.org/W1995924629","https://openalex.org/W1997044852","https://openalex.org/W1999689481","https://openalex.org/W2001010204","https://openalex.org/W2005383788","https://openalex.org/W2014669590","https://openalex.org/W2018287603","https://openalex.org/W2021323848","https://openalex.org/W2023966699","https://openalex.org/W2024532282","https://openalex.org/W2031065479","https://openalex.org/W2031586145","https://openalex.org/W2035307096","https://openalex.org/W2036693613","https://openalex.org/W2043441272","https://openalex.org/W2049290414","https://openalex.org/W2055976805","https://openalex.org/W2056375233","https://openalex.org/W2056944389","https://openalex.org/W2058901530","https://openalex.org/W2060333964","https://openalex.org/W2067708969","https://openalex.org/W2070851087","https://openalex.org/W2076521338","https://openalex.org/W2079115295","https://openalex.org/W2081422975","https://openalex.org/W2084300342","https://openalex.org/W2094199438","https://openalex.org/W2111538369","https://openalex.org/W2118212214","https://openalex.org/W2122734844","https://openalex.org/W2132309525","https://openalex.org/W2137417707","https://openalex.org/W2138714006","https://openalex.org/W2140834315","https://openalex.org/W2148282532","https://openalex.org/W2160395961","https://openalex.org/W2165113979","https://openalex.org/W2179223689","https://openalex.org/W2199768547","https://openalex.org/W4205090231"],"related_works":["https://openalex.org/W1980871522","https://openalex.org/W1982213102","https://openalex.org/W2130273189","https://openalex.org/W2103678239","https://openalex.org/W2074896243","https://openalex.org/W2072344627","https://openalex.org/W2118212214","https://openalex.org/W2011004481","https://openalex.org/W1545624987","https://openalex.org/W2370602638"],"abstract_inverted_index":{"The":[0,254],"progressive":[1],"differentiation":[2,103,198],"of":[3,17,25,37,44,57,76,107,117,134,137,145,165,174,211,226,251,259,275,283],"both":[4,70,102,179,227,284],"normal":[5],"rat":[6],"osteoblasts":[7,71,159,228],"and":[8,72,82,94,128,156,160,173,197,203,229,287],"HL-60":[9,73,171,191,230],"promyelocytic":[10],"leukemia":[11],"cells":[12,74,172,192],"involves":[13],"the":[14,34,45,54,89,105,115,138,143,209,212,223,234,238,249,262,281],"sequential":[15],"expression":[16,36,52,75,93,106,133,260],"specific":[18],"genes":[19,241,266],"encoding":[20],"proteins":[21],"that":[22,97],"are":[23,123,242,267],"characteristic":[24],"their":[26],"respective":[27],"developing":[28],"cellular":[29,95],"phenotypes.":[30],"In":[31,101],"addition":[32],"to":[33,236,280],"selective":[35],"various":[38,213,263],"phenotype":[39],"marker":[40],"genes,":[41],"several":[42],"members":[43,136],"heat":[46,239,264],"shock":[47,240,265],"gene":[48,92],"family":[49,140],"exhibit":[50],"differential":[51],"throughout":[53,222],"developmental":[55,224],"sequence":[56,225],"these":[58],"two":[59,135],"cell":[60,285],"types.":[61],"As":[62],"determined":[63],"by":[64],"steady":[65],"state":[66],"mRNA":[67,109,121,132,154,168,177,182,215],"levels,":[68],"in":[69,91,158,163,170,178,190,233,246,257,271],"hsp27,":[77],"hsp60,":[78],"hsp70,":[79],"hsp89":[80,83,152,166,175],"alpha,":[81],"beta":[84,176],"may":[85],"be":[86],"associated":[87],"with":[88,114,142,147,248,269],"modifications":[90],"architecture":[96],"occur":[98,244],"during":[99,125,194],"differentiation.":[100,288],"systems,":[104],"hsp27":[108],"shows":[110],"a":[111,148,161,273],"2.5-fold":[112],"increase":[113],"down-regulation":[116,164],"proliferation":[118,127,157,188],"while":[119],"hsp60":[120],"levels":[122,155,169],"maximal":[124],"active":[126],"subsequently":[129],"decline":[130,250],"post-proliferatively.":[131],"hsp90":[139],"decreases":[141,189],"shutdown":[144],"proliferation,":[146],"parallel":[149],"relationship":[150],"between":[151],"alpha":[153,167],"delay":[162],"systems.":[180],"Hsp70":[181],"rapidly":[183],"increases,":[184],"almost":[185],"twofold,":[186],"as":[187],"but":[193],"osteoblast":[195],"growth":[196,286],"was":[199],"only":[200],"minimally":[201],"detectable":[202],"showed":[204],"no":[205],"significant":[206],"changes.":[207],"Although":[208],"presence":[210],"hsp":[214],"species":[216],"is":[217],"maintained":[218],"at":[219],"some":[220],"level":[221],"cells,":[231],"changes":[232],"extent":[235],"which":[237],"expressed":[243],"primarily":[245],"association":[247],"proliferative":[252],"activity.":[253],"observed":[255],"differences":[256],"patterns":[258],"for":[261],"consistent":[268],"involvement":[270],"mediating":[272],"series":[274],"regulatory":[276],"events":[277],"functionally":[278],"related":[279],"control":[282]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}