{"id":"https://openalex.org/W1998708173","doi":"https://doi.org/10.1016/s0920-1211(00)00095-4","title":"Changes in synaptosomal ectonucleotidase activities in two rat models of temporal lobe epilepsy","display_name":"Changes in synaptosomal ectonucleotidase activities in two rat models of temporal lobe epilepsy","publication_year":2000,"publication_date":"2000-05-01","ids":{"openalex":"https://openalex.org/W1998708173","doi":"https://doi.org/10.1016/s0920-1211(00)00095-4","mag":"1998708173","pmid":"https://pubmed.ncbi.nlm.nih.gov/10771249"},"language":"en","primary_location":{"id":"doi:10.1016/s0920-1211(00)00095-4","doi":"https://doi.org/10.1016/s0920-1211(00)00095-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0920-1211(00)00095-4","pdf_url":null,"source":{"id":"https://openalex.org/S144140688","display_name":"Epilepsy Research","issn_l":"0920-1211","issn":["0920-1211","1872-6844"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/10923/23038","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068680303","display_name":"Carla Denise Bonan","orcid":"https://orcid.org/0000-0001-9715-6244","observed_orcids":["https://orcid.org/0000-0001-9715-6244"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"C.D Bonan","raw_affiliation_strings":["Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, Brazil","Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056338380","display_name":"Roger Walz","orcid":"https://orcid.org/0000-0002-9875-6687","observed_orcids":["https://orcid.org/0000-0002-9875-6687"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"R Walz","raw_affiliation_strings":["Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086168477","display_name":"Grace Schenatto Pereira","orcid":"https://orcid.org/0000-0003-4371-7020","observed_orcids":["https://orcid.org/0000-0003-4371-7020"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"G.S Pereira","raw_affiliation_strings":["Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038004187","display_name":"Paulo Valdeci Worm","orcid":"https://orcid.org/0000-0002-2639-2386","observed_orcids":["https://orcid.org/0000-0002-2639-2386"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"P.V Worm","raw_affiliation_strings":["Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049562552","display_name":"Ana Maria Oliveira Battastini","orcid":"https://orcid.org/0000-0001-6068-3278","observed_orcids":["https://orcid.org/0000-0001-6068-3278"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"A.M.O Battastini","raw_affiliation_strings":["Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032699063","display_name":"\u00c9sper A. Cavalheiro","orcid":"https://orcid.org/0000-0002-0854-3582","observed_orcids":["https://orcid.org/0000-0002-0854-3582"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E.A Cavalheiro","raw_affiliation_strings":["Neurologia Experimental, Escola Paulista de Medicina, S\u00e3o Paulo, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurologia Experimental, Escola Paulista de Medicina, S\u00e3o Paulo, SP, Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077801380","display_name":"Iv\u00e1n Izquierdo","orcid":"https://orcid.org/0000-0002-7208-0869","observed_orcids":["https://orcid.org/0000-0002-7208-0869"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"I Izquierdo","raw_affiliation_strings":["Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111712183","display_name":"J. J. F. Sarkis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"J.J.F Sarkis","raw_affiliation_strings":["Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u0131\u0301mica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600-ANEXO, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Departamento de Bioqu\u00edmica, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-Anexo, 90035-003, Porto Alegre, RS, Brazil","institution_ids":["https://openalex.org/I130442723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111712183"],"corresponding_institution_ids":["https://openalex.org/I130442723"],"apc_list":{"value":2880,"currency":"USD","value_usd":2880},"apc_paid":null,"fwci":3.1104,"has_fulltext":false,"cited_by_count":107,"citation_normalized_percentile":{"value":0.91106692,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"39","issue":"3","first_page":"229","last_page":"238"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.8140000104904175,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.8140000104904175,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11193","display_name":"Adenosine and Purinergic Signaling","score":0.1615000069141388,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ectonucleotidases","display_name":"ectonucleotidases","score":0.8539999723434448},{"id":"https://openalex.org/keywords/apyrase","display_name":"apyrase","score":0.925000011920929},{"id":"https://openalex.org/keywords/5-nucleotidase","display_name":"5'-nucleotidase","score":0.9950000047683716},{"id":"https://openalex.org/keywords/adenosine","display_name":"adenosine","score":0.7540000081062317},{"id":"https://openalex.org/keywords/temporal-lobe-epilepsy","display_name":"temporal lobe epilepsy","score":0.8970000147819519},{"id":"https://openalex.org/keywords/status-epilepticus","display_name":"status epilepticus","score":0.9929999709129333},{"id":"https://openalex.org/keywords/pilocarpine","display_name":"pilocarpine","score":0.8519999980926514},{"id":"https://openalex.org/keywords/kainic-acid","display_name":"kainic acid","score":0.9760000109672546},{"id":"https://openalex.org/keywords/synaptosomes","display_name":"synaptosomes","score":0.8899999856948853},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.996999979019165},{"id":"https://openalex.org/keywords/cerebral-cortex","display_name":"cerebral cortex","score":0.9919999837875366},{"id":"https://openalex.org/keywords/antiepileptic-drugs","display_name":"antiepileptic drugs","score":0.7379999756813049}],"concepts":[{"id":"https://openalex.org/C2777341932","wikidata":"https://www.wikidata.org/wiki/Q980709","display_name":"Status epilepticus","level":3,"score":0.6587076187133789},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.6119843125343323},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6031043529510498},{"id":"https://openalex.org/C2776991684","wikidata":"https://www.wikidata.org/wiki/Q190012","display_name":"Adenosine","level":2,"score":0.5969823598861694},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5522791147232056},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.5518643260002136},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.5196858048439026},{"id":"https://openalex.org/C189184402","wikidata":"https://www.wikidata.org/wiki/Q3454536","display_name":"Kainate receptor","level":5,"score":0.5064514875411987},{"id":"https://openalex.org/C2777204577","wikidata":"https://www.wikidata.org/wiki/Q411461","display_name":"Pilocarpine","level":3,"score":0.4967556595802307},{"id":"https://openalex.org/C2777913276","wikidata":"https://www.wikidata.org/wiki/Q24775951","display_name":"5'-nucleotidase","level":3,"score":0.4601792097091675},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4037725627422333},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3405672311782837},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29989033937454224},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27548572421073914},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.12480351328849792},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.06455734372138977},{"id":"https://openalex.org/C160268369","wikidata":"https://www.wikidata.org/wiki/Q295251","display_name":"AMPA receptor","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000251","descriptor_name":"Adenosine Triphosphatases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001081","descriptor_name":"Apyrase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004833","descriptor_name":"Epilepsy, Temporal Lobe","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D004833","descriptor_name":"Epilepsy, Temporal Lobe","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007608","descriptor_name":"Kainic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010862","descriptor_name":"Pilocarpine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013347","descriptor_name":"Subcellular Fractions","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D013574","descriptor_name":"Synaptosomes","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D015720","descriptor_name":"5'-Nucleotidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018690","descriptor_name":"Excitatory Amino Acid Agonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018721","descriptor_name":"Muscarinic Agonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/s0920-1211(00)00095-4","doi":"https://doi.org/10.1016/s0920-1211(00)00095-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0920-1211(00)00095-4","pdf_url":null,"source":{"id":"https://openalex.org/S144140688","display_name":"Epilepsy Research","issn_l":"0920-1211","issn":["0920-1211","1872-6844"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy Research","raw_type":"journal-article"},{"id":"pmid:10771249","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10771249","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy research","raw_type":"Journal Article"},{"id":"pmh:oai:meriva.pucrs.br:10923/23038","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10923/23038","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:PUC_RS","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:repositorio.unifesp.br:11600/26306","doi":null,"is_oa":false,"landing_page_url":"http://repositorio.unifesp.br/handle/11600/26306","pdf_url":null,"source":{"id":"https://openalex.org/S4377196380","display_name":"UNIFESP Institutional Repository (Universidade Federal de S\u00e3o Paulo)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I88273585","host_organization_name":"Universidade Federal de S\u00e3o Paulo","host_organization_lineage":["https://openalex.org/I88273585"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Artigo"}],"best_oa_location":{"id":"pmh:oai:meriva.pucrs.br:10923/23038","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10923/23038","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:PUC_RS","raw_type":"info:eu-repo/semantics/publishedVersion"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320322904","display_name":"Financiadora de Estudos e Projetos","ror":"https://ror.org/030w99567"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W60693574","https://openalex.org/W198961190","https://openalex.org/W1479790262","https://openalex.org/W1485999720","https://openalex.org/W1511707795","https://openalex.org/W1918855189","https://openalex.org/W1969272335","https://openalex.org/W1969761928","https://openalex.org/W1972546896","https://openalex.org/W1974260260","https://openalex.org/W1977991702","https://openalex.org/W1981637709","https://openalex.org/W1985818735","https://openalex.org/W1987545181","https://openalex.org/W1988358396","https://openalex.org/W1998098499","https://openalex.org/W1998454224","https://openalex.org/W2006497495","https://openalex.org/W2009401980","https://openalex.org/W2011391497","https://openalex.org/W2012462745","https://openalex.org/W2016832867","https://openalex.org/W2023718938","https://openalex.org/W2023828382","https://openalex.org/W2030307932","https://openalex.org/W2033456548","https://openalex.org/W2034271730","https://openalex.org/W2045270601","https://openalex.org/W2050043728","https://openalex.org/W2054974598","https://openalex.org/W2069488037","https://openalex.org/W2071501185","https://openalex.org/W2075846042","https://openalex.org/W2076302671","https://openalex.org/W2077682140","https://openalex.org/W2078333644","https://openalex.org/W2082539152","https://openalex.org/W2092700031","https://openalex.org/W2094319340","https://openalex.org/W2104419986","https://openalex.org/W2128635872","https://openalex.org/W2135842147","https://openalex.org/W2160262187","https://openalex.org/W2171193971","https://openalex.org/W2434828851","https://openalex.org/W6602388378"],"related_works":["https://openalex.org/W2009140080","https://openalex.org/W74883566","https://openalex.org/W2042968400","https://openalex.org/W1985818735","https://openalex.org/W2139669380","https://openalex.org/W4235211777","https://openalex.org/W2010674569","https://openalex.org/W7095570667","https://openalex.org/W1993223096","https://openalex.org/W2031449820"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}