{"id":"https://openalex.org/W1998707288","doi":"https://doi.org/10.5114/aoms.2013.35347","title":"Cost-effectiveness analysis review of exemestane in the treatment of primary and advanced breast cancer","display_name":"Cost-effectiveness analysis review of exemestane in the treatment of primary and advanced breast cancer","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W1998707288","doi":"https://doi.org/10.5114/aoms.2013.35347","mag":"1998707288","pmid":"https://pubmed.ncbi.nlm.nih.gov/23847669","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3701982"},"language":"en","primary_location":{"id":"doi:10.5114/aoms.2013.35347","doi":"https://doi.org/10.5114/aoms.2013.35347","is_oa":true,"landing_page_url":"https://doi.org/10.5114/aoms.2013.35347","pdf_url":"https://www.archivesofmedicalscience.com/pdf-53204-58697?filename=Clinical.pdf","source":{"id":"https://openalex.org/S30890154","display_name":"Archives of Medical Science","issn_l":"1734-1922","issn":["1734-1922","1896-9151"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320332","host_organization_name":"Termedia Publishing House","host_organization_lineage":["https://openalex.org/P4310320332"],"host_organization_lineage_names":["Termedia Publishing House"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Medical Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.archivesofmedicalscience.com/pdf-53204-58697?filename=Clinical.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033895640","display_name":"Amir Hashemi-Meshkini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4403928236","display_name":"Endocrine and Metabolism Research Center","ror":"https://ror.org/034qe8j39","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928185","https://openalex.org/I4403928236","https://openalex.org/I4403928377","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I4403928356","display_name":"Non-Communicable Diseases Research Center","ror":"https://ror.org/01nspwd23","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928192","https://openalex.org/I4403928356","https://openalex.org/I4403928377","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Amir Hashemi-Meshkini","raw_affiliation_strings":["Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran ; Non-Communicable Disease Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran ; Non-Communicable Disease Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I4403928236","https://openalex.org/I4403928356","https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071078396","display_name":"Khosro Keshavarz","orcid":"https://orcid.org/0000-0002-5778-5502","observed_orcids":["https://orcid.org/0000-0002-5778-5502"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Khosro Keshavarz","raw_affiliation_strings":["Department of Pharmacoeconomics and Pharmaceutical Administration , Faculty of Pharmacy , Tehran University of Medical Sciences , Tehran , Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacoeconomics and Pharmaceutical Administration , Faculty of Pharmacy , Tehran University of Medical Sciences , Tehran , Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070671985","display_name":"Zahra Gharibnaseri","orcid":"https://orcid.org/0000-0002-3997-5919","observed_orcids":["https://orcid.org/0000-0002-3997-5919"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Zahra Gharibnaseri","raw_affiliation_strings":["Department of Pharmacoeconomics and Pharmaceutical Administration , Faculty of Pharmacy , Tehran University of Medical Sciences , Tehran , Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacoeconomics and Pharmaceutical Administration , Faculty of Pharmacy , Tehran University of Medical Sciences , Tehran , Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029888125","display_name":"Mehrnaz Kheirandish","orcid":"https://orcid.org/0000-0001-5320-6481","observed_orcids":["https://orcid.org/0000-0001-5320-6481"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mehrnaz Kheirandish","raw_affiliation_strings":["Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078712152","display_name":"Abbas Kebriaeezadeh","orcid":"https://orcid.org/0000-0003-3872-2474","observed_orcids":["https://orcid.org/0000-0003-3872-2474"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Abbas Kebriaeezadeh","raw_affiliation_strings":["Department of Pharmacoeconomics and Pharmaceutical Administration , Faculty of Pharmacy , Tehran University of Medical Sciences , Tehran , Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacoeconomics and Pharmaceutical Administration , Faculty of Pharmacy , Tehran University of Medical Sciences , Tehran , Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025053518","display_name":"Shekoufeh Nikfar","orcid":"https://orcid.org/0000-0002-5206-6197","observed_orcids":["https://orcid.org/0000-0002-5206-6197"]},"institutions":[{"id":"https://openalex.org/I4210110574","display_name":"Ministry of Health and Medical Education","ror":"https://ror.org/01rs0ht88","country_code":"IR","type":"government","lineage":["https://openalex.org/I4210110574"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Shekoufeh Nikfar","raw_affiliation_strings":["Department of Pharmacoeconomics and Pharmaceutical Administration , Faculty of Pharmacy , Tehran University of Medical Sciences , Tehran , Iran","Food and Drug Organization , Ministry of Health and Medical Education , Tehran , Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacoeconomics and Pharmaceutical Administration , Faculty of Pharmacy , Tehran University of Medical Sciences , Tehran , Iran","institution_ids":["https://openalex.org/I70640408"]},{"raw_affiliation_string":"Food and Drug Organization , Ministry of Health and Medical Education , Tehran , Iran","institution_ids":["https://openalex.org/I4210110574"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068915111","display_name":"Mohammad Reza Abdollahi","orcid":"https://orcid.org/0000-0003-0123-1209","observed_orcids":["https://orcid.org/0000-0003-0123-1209","https://orcid.org/0009-0001-0204-3093"]},"institutions":[{"id":"https://openalex.org/I4403928403","display_name":"Pharmaceutical Sciences Research Center","ror":"https://ror.org/02m2rj159","country_code":"IR","type":"facility","lineage":["https://openalex.org/I4403928403","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Mohammad Abdollahi","raw_affiliation_strings":["Department of Toxicology and Pharmacology , Faculty of Pharmacy , and Pharmaceutical Sciences Research Center , Tehran University of Medical Sciences , Tehran , Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology and Pharmacology , Faculty of Pharmacy , and Pharmaceutical Sciences Research Center , Tehran University of Medical Sciences , Tehran , Iran","institution_ids":["https://openalex.org/I4403928403","https://openalex.org/I70640408"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5025053518","https://openalex.org/A5068915111"],"corresponding_institution_ids":["https://openalex.org/I4210110574","https://openalex.org/I4403928403","https://openalex.org/I70640408"],"apc_list":{"value":1000,"currency":"EUR","value_usd":1078},"apc_paid":{"value":1000,"currency":"EUR","value_usd":1078},"fwci":4.2392,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.93928729,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"3","issue":"3","first_page":"472","last_page":"478"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exemestane","display_name":"exemestane","score":1.0},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9110000133514404},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.9399999976158142},{"id":"https://openalex.org/keywords/adjuvant-endocrine-therapy","display_name":"adjuvant endocrine therapy","score":0.878000020980835},{"id":"https://openalex.org/keywords/tamoxifen","display_name":"tamoxifen","score":0.8140000104904175},{"id":"https://openalex.org/keywords/anastrozole","display_name":"anastrozole","score":0.9670000076293945},{"id":"https://openalex.org/keywords/megestrol-acetate","display_name":"megestrol acetate","score":0.9919999837875366},{"id":"https://openalex.org/keywords/metastatic-breast-cancer","display_name":"metastatic breast cancer","score":0.9290000200271606},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.8209999799728394},{"id":"https://openalex.org/keywords/overall-response","display_name":"overall response","score":0.5690000057220459}],"concepts":[{"id":"https://openalex.org/C2775860665","wikidata":"https://www.wikidata.org/wiki/Q418819","display_name":"Exemestane","level":5,"score":0.9760315418243408},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8940813541412354},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6931880712509155},{"id":"https://openalex.org/C2777176818","wikidata":"https://www.wikidata.org/wiki/Q412178","display_name":"Tamoxifen","level":4,"score":0.6831194162368774},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6261038780212402},{"id":"https://openalex.org/C2776215463","wikidata":"https://www.wikidata.org/wiki/Q419143","display_name":"Anastrozole","level":5,"score":0.5814950466156006},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5647500157356262},{"id":"https://openalex.org/C3019080777","wikidata":"https://www.wikidata.org/wiki/Q1754768","display_name":"Cost effectiveness","level":2,"score":0.49729683995246887},{"id":"https://openalex.org/C2777863537","wikidata":"https://www.wikidata.org/wiki/Q357896","display_name":"Adjuvant","level":2,"score":0.4252951741218567},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3856455385684967},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.37842634320259094},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.5114/aoms.2013.35347","doi":"https://doi.org/10.5114/aoms.2013.35347","is_oa":true,"landing_page_url":"https://doi.org/10.5114/aoms.2013.35347","pdf_url":"https://www.archivesofmedicalscience.com/pdf-53204-58697?filename=Clinical.pdf","source":{"id":"https://openalex.org/S30890154","display_name":"Archives of Medical Science","issn_l":"1734-1922","issn":["1734-1922","1896-9151"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320332","host_organization_name":"Termedia Publishing House","host_organization_lineage":["https://openalex.org/P4310320332"],"host_organization_lineage_names":["Termedia Publishing House"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Medical Science","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2703304","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3701982","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3701982","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3701982","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arch Med Sci","raw_type":"Text"},{"id":"pmid:23847669","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23847669","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of medical science : AMS","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.5114/aoms.2013.35347","doi":"https://doi.org/10.5114/aoms.2013.35347","is_oa":true,"landing_page_url":"https://doi.org/10.5114/aoms.2013.35347","pdf_url":"https://www.archivesofmedicalscience.com/pdf-53204-58697?filename=Clinical.pdf","source":{"id":"https://openalex.org/S30890154","display_name":"Archives of Medical Science","issn_l":"1734-1922","issn":["1734-1922","1896-9151"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320332","host_organization_name":"Termedia Publishing House","host_organization_lineage":["https://openalex.org/P4310320332"],"host_organization_lineage_names":["Termedia Publishing House"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Medical Science","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322244","display_name":"Ministry of Health and Medical Education","ror":"https://ror.org/01rs0ht88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1998707288.pdf","grobid_xml":"https://content.openalex.org/works/W1998707288.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1508762963","https://openalex.org/W1780488041","https://openalex.org/W1977645603","https://openalex.org/W2022013833","https://openalex.org/W2029084097","https://openalex.org/W2031428574","https://openalex.org/W2032144589","https://openalex.org/W2042960078","https://openalex.org/W2073202647","https://openalex.org/W2079001302","https://openalex.org/W2088885993","https://openalex.org/W2114441429","https://openalex.org/W2116538089","https://openalex.org/W2131398863","https://openalex.org/W2139023087","https://openalex.org/W2152591722","https://openalex.org/W2165948908","https://openalex.org/W2167238270","https://openalex.org/W2202169216","https://openalex.org/W2307998267","https://openalex.org/W2315747388","https://openalex.org/W2327173267","https://openalex.org/W2496332660"],"related_works":["https://openalex.org/W2013424358","https://openalex.org/W2022013833","https://openalex.org/W1964921635","https://openalex.org/W2770707895","https://openalex.org/W2029084097","https://openalex.org/W1988695273","https://openalex.org/W1984676603","https://openalex.org/W2088885993","https://openalex.org/W1991721331","https://openalex.org/W2328987485"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Exemestane":[1],"was":[2,40,84,152,167,197],"approved":[3],"in":[4,23,108,193,200,215,230],"2005":[5],"for":[6,86,186,246],"adjuvant":[7],"treatment":[8,134,157,229],"of":[9,35,48,63,66,125,141,202,217],"breast":[10,92,149,234],"cancer.":[11],"In":[12,147],"this":[13,194],"study,":[14],"we":[15],"aimed":[16],"to":[17,25],"assess":[18],"whether":[19],"it":[20,196],"is":[21,243],"cost-effective":[22,105,156,169,199,228],"comparison":[24],"available":[26,96,238],"alternatives.":[27,239],"MATERIAL":[28],"AND":[29],"METHODS:":[30],"To":[31,59],"evaluate":[32,60],"the":[33,61,79,203],"efficacy":[34],"exemestane,":[36],"a":[37,104,155,227],"systematic":[38],"review":[39],"conducted":[41],"by":[42,135],"searching":[43],"electronic":[44],"databases.":[45],"The":[46],"outcomes":[47],"interest":[49],"were":[50,74],"\"clinical":[51],"benefit\",":[52],"\"overall":[53],"response\"":[54],"and":[55,70,78,118,129,131,137,144,162,166,175,188,212,232],"\"disease-free":[56],"survival":[57,205],"rate\".":[58],"cost":[62],"treatments,":[64],"costs":[65,214],"both":[67,160],"domestic":[68],"generic":[69,109,187],"imported":[71],"brand":[72,111,189],"medicines":[73],"taken":[75],"into":[76],"account,":[77],"incremental":[80],"cost-effectiveness":[81],"ratio":[82],"(ICER)":[83],"calculated":[85],"each":[87],"comparison.":[88],"RESULTS:":[89],"Regarding":[90,209],"primary":[91,231],"cancer,":[93,150],"based":[94],"upon":[95],"evidence,":[97],"exemestane":[98,138,151,222],"could":[99,223],"not":[100,153,198,224],"be":[101,225],"considered":[102,154,226],"as":[103],"medicine":[106],"either":[107],"or":[110],"form":[112],"compared":[113,158,170,236],"with":[114,120,132,159,171,182,237],"placebo":[115],"(ICER:":[116,127],"119,100":[117],"215,525),":[119],"tamoxifen":[121,136,172],"after":[122],"2-3":[123],"years":[124],"therapy":[126],"35,150":[128],"82,400)":[130],"sequential":[133],"(dominated":[139],"because":[140],"lower":[142],"effectiveness":[143],"higher":[145],"cost).":[146],"metastatic":[148],"anastrozole":[161],"megestrol":[163],"acetate":[164],"(dominated)":[165],"highly":[168],"(ICERs:":[173],"2,208":[174],"4,326":[176],"dollars":[177],"per":[178],"one":[179],"more":[180,241,247],"patient":[181],"an":[183],"overall":[184],"response":[185],"medicines)":[190],"although":[191],"even":[192],"case":[195],"terms":[201,216],"1-year":[204],"rates":[206],"(dominated).":[207],"CONCLUSIONS:":[208],"current":[210],"evidence":[211,242],"related":[213],"Iranian":[218],"pharmaceutical":[219],"market":[220],"prices,":[221],"advanced":[233],"cancer":[235],"However,":[240],"still":[244],"needed":[245],"certain":[248],"decisions.":[249]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}
