{"id":"https://openalex.org/W1998624544","doi":"https://doi.org/10.1016/j.jinorgbio.2007.10.008","title":"Synthesis, characterization and antiproliferative activity of metal complexes with the Schiff base derived from the condensation 1:2 of 2,6-diformyl-4-methylphenol and 5,6-diamino-1,3-dimethyluracil","display_name":"Synthesis, characterization and antiproliferative activity of metal complexes with the Schiff base derived from the condensation 1:2 of 2,6-diformyl-4-methylphenol and 5,6-diamino-1,3-dimethyluracil","publication_year":2007,"publication_date":"2007-10-25","ids":{"openalex":"https://openalex.org/W1998624544","doi":"https://doi.org/10.1016/j.jinorgbio.2007.10.008","mag":"1998624544","pmid":"https://pubmed.ncbi.nlm.nih.gov/18037489"},"language":"en","primary_location":{"id":"doi:10.1016/j.jinorgbio.2007.10.008","doi":"https://doi.org/10.1016/j.jinorgbio.2007.10.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jinorgbio.2007.10.008","pdf_url":null,"source":{"id":"https://openalex.org/S155362585","display_name":"Journal of Inorganic Biochemistry","issn_l":"0162-0134","issn":["0162-0134","1873-3344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Inorganic Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027031285","display_name":"Nuria A. Ill\u00e1n\u2010Cabeza","orcid":"https://orcid.org/0000-0002-1646-8383","observed_orcids":["https://orcid.org/0000-0002-1646-8383"]},"institutions":[{"id":"https://openalex.org/I191420491","display_name":"Universidad de Ja\u00e9n","ror":"https://ror.org/0122p5f64","country_code":"ES","type":"education","lineage":["https://openalex.org/I191420491"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Nuria A. Ill\u00e1n-Cabeza","raw_affiliation_strings":["Departamento de Qu\u00edmica Inorg\u00e1nica y Org\u00e1nica, Facultad de Ciencias Experimentales, Universidad de Ja\u00e9n, Paraje Las Lagunillas s/n, 23071 Ja\u00e9n, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Qu\u00edmica Inorg\u00e1nica y Org\u00e1nica, Facultad de Ciencias Experimentales, Universidad de Ja\u00e9n, Paraje Las Lagunillas s/n, 23071 Ja\u00e9n, Spain","institution_ids":["https://openalex.org/I191420491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011727058","display_name":"Francisco Hueso\u2010Ure\u00f1a","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I191420491","display_name":"Universidad de Ja\u00e9n","ror":"https://ror.org/0122p5f64","country_code":"ES","type":"education","lineage":["https://openalex.org/I191420491"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Francisco Hueso-Ure\u00f1a","raw_affiliation_strings":["Departamento de Qu\u00edmica Inorg\u00e1nica y Org\u00e1nica, Facultad de Ciencias Experimentales, Universidad de Ja\u00e9n, Paraje Las Lagunillas s/n, 23071 Ja\u00e9n, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Qu\u00edmica Inorg\u00e1nica y Org\u00e1nica, Facultad de Ciencias Experimentales, Universidad de Ja\u00e9n, Paraje Las Lagunillas s/n, 23071 Ja\u00e9n, Spain","institution_ids":["https://openalex.org/I191420491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003710957","display_name":"Miguel N. Moreno\u2010Carretero","orcid":"https://orcid.org/0000-0001-7466-5353","observed_orcids":["https://orcid.org/0000-0001-7466-5353"]},"institutions":[{"id":"https://openalex.org/I191420491","display_name":"Universidad de Ja\u00e9n","ror":"https://ror.org/0122p5f64","country_code":"ES","type":"education","lineage":["https://openalex.org/I191420491"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Miguel N. Moreno-Carretero","raw_affiliation_strings":["Departamento de Qu\u00edmica Inorg\u00e1nica y Org\u00e1nica, Facultad de Ciencias Experimentales, Universidad de Ja\u00e9n, Paraje Las Lagunillas s/n, 23071 Ja\u00e9n, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Qu\u00edmica Inorg\u00e1nica y Org\u00e1nica, Facultad de Ciencias Experimentales, Universidad de Ja\u00e9n, Paraje Las Lagunillas s/n, 23071 Ja\u00e9n, Spain","institution_ids":["https://openalex.org/I191420491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052352950","display_name":"Jos\u00e9 Manuel Mart\u00ednez-Martos","orcid":"https://orcid.org/0000-0002-2950-5614","observed_orcids":["https://orcid.org/0000-0002-2950-5614"]},"institutions":[{"id":"https://openalex.org/I191420491","display_name":"Universidad de Ja\u00e9n","ror":"https://ror.org/0122p5f64","country_code":"ES","type":"education","lineage":["https://openalex.org/I191420491"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 M. Mart\u00ednez-Martos","raw_affiliation_strings":["Departamento de Ciencias de la Salud, Universidad de Ja\u00e9n, 23071 Ja\u00e9n, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Ciencias de la Salud, Universidad de Ja\u00e9n, 23071 Ja\u00e9n, Spain","institution_ids":["https://openalex.org/I191420491"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034709965","display_name":"Mar\u00eda Jes\u00fas Ram\u00edrez-Exp\u00f3sito","orcid":"https://orcid.org/0000-0002-9379-203X","observed_orcids":["https://orcid.org/0000-0002-9379-203X"]},"institutions":[{"id":"https://openalex.org/I191420491","display_name":"Universidad de Ja\u00e9n","ror":"https://ror.org/0122p5f64","country_code":"ES","type":"education","lineage":["https://openalex.org/I191420491"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Mar\u00eda J. Ram\u00edrez-Exp\u00f3sito","raw_affiliation_strings":["Departamento de Ciencias de la Salud, Universidad de Ja\u00e9n, 23071 Ja\u00e9n, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Ciencias de la Salud, Universidad de Ja\u00e9n, 23071 Ja\u00e9n, Spain","institution_ids":["https://openalex.org/I191420491"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5003710957"],"corresponding_institution_ids":["https://openalex.org/I191420491"],"apc_list":{"value":4220,"currency":"USD","value_usd":4220},"apc_paid":null,"fwci":0.3549,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.64644974,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"102","issue":"4","first_page":"647","last_page":"655"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11746","display_name":"Inorganic and Organometallic Chemistry","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10464","display_name":"Crystal structures of chemical compounds","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schiff-base-ligands","display_name":"Schiff base ligands","score":0.8759999871253967},{"id":"https://openalex.org/keywords/coordination-compounds","display_name":"metal complexes","score":0.8840000033378601},{"id":"https://openalex.org/keywords/2-6-diformyl-4-methylphenol","display_name":"2,6-diformyl-4-methylphenol","score":0.9700000286102295},{"id":"https://openalex.org/keywords/antiproliferative-activity","display_name":"antiproliferative activity","score":0.7929999828338623},{"id":"https://openalex.org/keywords/estrogenic-activity","display_name":"estrogenic activity","score":0.7350000143051147},{"id":"https://openalex.org/keywords/coordination-modes","display_name":"coordination modes","score":0.6079999804496765},{"id":"https://openalex.org/keywords/tridentate-coordination","display_name":"tridentate coordination","score":0.656000018119812},{"id":"https://openalex.org/keywords/molybdenum-vi-complexes","display_name":"molybdenum(VI) complexes","score":0.7760000228881836},{"id":"https://openalex.org/keywords/cobalt-ii-complexes","display_name":"cobalt(II) complexes","score":0.8379999995231628},{"id":"https://openalex.org/keywords/nickel-ii-complexes","display_name":"nickel(II) complexes","score":0.9010000228881836},{"id":"https://openalex.org/keywords/cu-ii-complexes","display_name":"copper(II) complexes","score":0.9929999709129333},{"id":"https://openalex.org/keywords/zinc-ii-complexes","display_name":"zinc(II) complexes","score":0.9959999918937683},{"id":"https://openalex.org/keywords/mercury-ii-complexes","display_name":"mercury(II) complexes","score":0.9800000190734863},{"id":"https://openalex.org/keywords/palladium-ii-complexes","display_name":"palladium(II) complexes","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cancer-cell-lines","display_name":"cancer cell lines","score":0.7070000171661377},{"id":"https://openalex.org/keywords/neuroblastoma","display_name":"neuroblastoma","score":0.7620000243186951},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9909999966621399},{"id":"https://openalex.org/keywords/glioma","display_name":"glioma","score":0.9879999756813049},{"id":"https://openalex.org/keywords/bladder-cancer","display_name":"bladder cancer","score":0.9670000076293945}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9569640755653381},{"id":"https://openalex.org/C2776428424","wikidata":"https://www.wikidata.org/wiki/Q2602701","display_name":"Schiff base","level":2,"score":0.8130968809127808},{"id":"https://openalex.org/C200093464","wikidata":"https://www.wikidata.org/wiki/Q166583","display_name":"Condensation","level":2,"score":0.7293539643287659},{"id":"https://openalex.org/C2780841128","wikidata":"https://www.wikidata.org/wiki/Q5073781","display_name":"Characterization (materials science)","level":2,"score":0.6664959192276001},{"id":"https://openalex.org/C42058472","wikidata":"https://www.wikidata.org/wiki/Q810214","display_name":"Base (topology)","level":2,"score":0.5807463526725769},{"id":"https://openalex.org/C544153396","wikidata":"https://www.wikidata.org/wiki/Q11426","display_name":"Metal","level":2,"score":0.5761290788650513},{"id":"https://openalex.org/C207245611","wikidata":"https://www.wikidata.org/wiki/Q910058","display_name":"Condensation reaction","level":3,"score":0.4971499741077423},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.45026400685310364},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.44898349046707153},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2705479860305786},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.18480858206748962},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.06060943007469177},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008670","descriptor_name":"Metals","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012545","descriptor_name":"Schiff Bases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013057","descriptor_name":"Spectrum Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014498","descriptor_name":"Uracil","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D014498","descriptor_name":"Uracil","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jinorgbio.2007.10.008","doi":"https://doi.org/10.1016/j.jinorgbio.2007.10.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jinorgbio.2007.10.008","pdf_url":null,"source":{"id":"https://openalex.org/S155362585","display_name":"Journal of Inorganic Biochemistry","issn_l":"0162-0134","issn":["0162-0134","1873-3344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Inorganic Biochemistry","raw_type":"journal-article"},{"id":"pmid:18037489","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18037489","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of inorganic biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W7243943","https://openalex.org/W24750850","https://openalex.org/W159579650","https://openalex.org/W239498777","https://openalex.org/W1516297516","https://openalex.org/W1968192672","https://openalex.org/W1969180486","https://openalex.org/W1987642916","https://openalex.org/W1988150138","https://openalex.org/W1993166122","https://openalex.org/W1995947652","https://openalex.org/W1998421170","https://openalex.org/W1998722626","https://openalex.org/W1999101633","https://openalex.org/W2006118631","https://openalex.org/W2022796085","https://openalex.org/W2048645097","https://openalex.org/W2055026238","https://openalex.org/W2055131693","https://openalex.org/W2057015058","https://openalex.org/W2057596304","https://openalex.org/W2063689594","https://openalex.org/W2066303306","https://openalex.org/W2080211304","https://openalex.org/W2085293698","https://openalex.org/W2085455922","https://openalex.org/W2092789517","https://openalex.org/W2095380224","https://openalex.org/W2119146606","https://openalex.org/W2146128373","https://openalex.org/W2148078655","https://openalex.org/W2324977215","https://openalex.org/W2335025943","https://openalex.org/W2595776066","https://openalex.org/W3022602249","https://openalex.org/W3102526660","https://openalex.org/W4233869395","https://openalex.org/W4242166356"],"related_works":["https://openalex.org/W159579650","https://openalex.org/W2971790446","https://openalex.org/W3022463488","https://openalex.org/W2036887380","https://openalex.org/W2744849466","https://openalex.org/W3171463141","https://openalex.org/W2906675107","https://openalex.org/W6911841173","https://openalex.org/W2994900736","https://openalex.org/W3211403861"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}