{"id":"https://openalex.org/W1998581209","doi":"https://doi.org/10.1016/0166-4328(90)90119-y","title":"Damage to ceruleo-cortical noradrenergic projections impairs locally cued but enhances spatially cued water maze acquisition","display_name":"Damage to ceruleo-cortical noradrenergic projections impairs locally cued but enhances spatially cued water maze acquisition","publication_year":1990,"publication_date":"1990-06-01","ids":{"openalex":"https://openalex.org/W1998581209","doi":"https://doi.org/10.1016/0166-4328(90)90119-y","mag":"1998581209","pmid":"https://pubmed.ncbi.nlm.nih.gov/2167691"},"language":"en","primary_location":{"id":"doi:10.1016/0166-4328(90)90119-y","doi":"https://doi.org/10.1016/0166-4328(90)90119-y","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0166-4328(90)90119-y","pdf_url":null,"source":{"id":"https://openalex.org/S81474683","display_name":"Behavioural Brain Research","issn_l":"0166-4328","issn":["0166-4328","1872-7549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Behavioural Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050958724","display_name":"Nathan R. W. Selden","orcid":"https://orcid.org/0000-0001-6108-9721","observed_orcids":["https://orcid.org/0000-0001-6108-9721"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nathan R.W. Selden","raw_affiliation_strings":["Department of Experimental Psychology, University of Cambridge, U.K","Department of Experimental Psychology University of Cambridge, Cambridge U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Psychology, University of Cambridge, U.K","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Department of Experimental Psychology University of Cambridge, Cambridge U.K","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020359088","display_name":"Belinda J. Cole","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Belinda J. Cole","raw_affiliation_strings":["Department of Experimental Psychology University of Cambridge, Cambridge U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Psychology University of Cambridge, Cambridge U.K","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040428174","display_name":"Barry J. Everitt","orcid":"https://orcid.org/0000-0003-4431-6536","observed_orcids":["https://orcid.org/0000-0003-4431-6536"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Barry J. Everitt","raw_affiliation_strings":["Department of Anatomy, University of Cambridge, Cambridge U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, University of Cambridge, Cambridge U.K","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080762339","display_name":"Trevor William Robbins","orcid":"https://orcid.org/0000-0003-0642-5977","observed_orcids":["https://orcid.org/0000-0003-0642-5977"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Trevor W. Robbins","raw_affiliation_strings":["Department of Experimental Psychology University of Cambridge, Cambridge U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Psychology University of Cambridge, Cambridge U.K","institution_ids":["https://openalex.org/I241749"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5080762339"],"corresponding_institution_ids":["https://openalex.org/I241749"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":null,"fwci":3.5949,"has_fulltext":false,"cited_by_count":80,"citation_normalized_percentile":{"value":0.93409807,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"39","issue":"1","first_page":"29","last_page":"51"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.7304999828338623,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.7304999828338623,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.2476000040769577,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.007300000172108412,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/norepinephrine-depletion","display_name":"norepinephrine depletion","score":0.902999997138977},{"id":"https://openalex.org/keywords/dorsal-noradrenergic-bundle","display_name":"dorsal noradrenergic bundle","score":0.9200000166893005},{"id":"https://openalex.org/keywords/ventral-noradrenergic-bundle","display_name":"ventral noradrenergic bundle","score":0.9700000286102295},{"id":"https://openalex.org/keywords/6-ohda-lesion","display_name":"6-hydroxydopamine lesion","score":0.8460000157356262},{"id":"https://openalex.org/keywords/dopamine-depletion","display_name":"dopamine depletion","score":0.6489999890327454},{"id":"https://openalex.org/keywords/caudate-putamen","display_name":"caudate-putamen","score":0.9779999852180481},{"id":"https://openalex.org/keywords/escape-learning","display_name":"escape learning","score":0.6840000152587891},{"id":"https://openalex.org/keywords/stress","display_name":"stress","score":0.7419999837875366},{"id":"https://openalex.org/keywords/cold-water-swimming","display_name":"cold water swimming","score":0.7210000157356262},{"id":"https://openalex.org/keywords/core-body-temperature","display_name":"core body temperature","score":0.859000027179718},{"id":"https://openalex.org/keywords/corticosterone","display_name":"corticosterone","score":0.9049999713897705},{"id":"https://openalex.org/keywords/swimming-speed","display_name":"swimming speed","score":0.5849999785423279}],"concepts":[{"id":"https://openalex.org/C12515866","wikidata":"https://www.wikidata.org/wiki/Q50628021","display_name":"Water maze","level":3,"score":0.5722043514251709},{"id":"https://openalex.org/C2776669363","wikidata":"https://www.wikidata.org/wiki/Q4287680","display_name":"Medial forebrain bundle","level":4,"score":0.570836067199707},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5364101529121399},{"id":"https://openalex.org/C44752575","wikidata":"https://www.wikidata.org/wiki/Q1417562","display_name":"Morris water navigation task","level":3,"score":0.4891693890094757},{"id":"https://openalex.org/C2778514916","wikidata":"https://www.wikidata.org/wiki/Q186242","display_name":"Norepinephrine","level":3,"score":0.42916440963745117},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4158497452735901},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4106261134147644},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.3811563551425934},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.2838953733444214},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.19874915480613708}],"mesh":[{"descriptor_ui":"D000679","descriptor_name":"Amygdala","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001143","descriptor_name":"Arousal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001833","descriptor_name":"Body Temperature Regulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003345","descriptor_name":"Corticosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003463","descriptor_name":"Cues","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004193","descriptor_name":"Discrimination Learning","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004924","descriptor_name":"Escape Reaction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008125","descriptor_name":"Locus Coeruleus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009949","descriptor_name":"Orientation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011941","descriptor_name":"Receptors, Adrenergic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0166-4328(90)90119-y","doi":"https://doi.org/10.1016/0166-4328(90)90119-y","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0166-4328(90)90119-y","pdf_url":null,"source":{"id":"https://openalex.org/S81474683","display_name":"Behavioural Brain Research","issn_l":"0166-4328","issn":["0166-4328","1872-7549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Behavioural Brain Research","raw_type":"journal-article"},{"id":"pmid:2167691","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2167691","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Behavioural brain research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.504800021648407,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.44999998807907104,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"},{"score":0.41999998688697815,"display_name":"Peace, justice, and strong institutions","id":"https://metadata.un.org/sdg/16"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":84,"referenced_works":["https://openalex.org/W102110531","https://openalex.org/W180932795","https://openalex.org/W210064051","https://openalex.org/W250922107","https://openalex.org/W640905404","https://openalex.org/W1130992432","https://openalex.org/W1565739360","https://openalex.org/W1608952396","https://openalex.org/W1657392694","https://openalex.org/W1763311249","https://openalex.org/W1853268599","https://openalex.org/W1924384005","https://openalex.org/W1965424617","https://openalex.org/W1965451600","https://openalex.org/W1974030758","https://openalex.org/W1974975426","https://openalex.org/W1977025722","https://openalex.org/W1977542480","https://openalex.org/W1987736778","https://openalex.org/W1995501628","https://openalex.org/W1997615506","https://openalex.org/W1997708388","https://openalex.org/W2002446850","https://openalex.org/W2010450314","https://openalex.org/W2012937418","https://openalex.org/W2013488993","https://openalex.org/W2017169966","https://openalex.org/W2020598149","https://openalex.org/W2023495542","https://openalex.org/W2031687445","https://openalex.org/W2032427582","https://openalex.org/W2032439104","https://openalex.org/W2032660227","https://openalex.org/W2032844445","https://openalex.org/W2033217075","https://openalex.org/W2034251427","https://openalex.org/W2048619611","https://openalex.org/W2050192143","https://openalex.org/W2050426362","https://openalex.org/W2050709677","https://openalex.org/W2053916401","https://openalex.org/W2054993348","https://openalex.org/W2056621949","https://openalex.org/W2057601539","https://openalex.org/W2060408061","https://openalex.org/W2067379667","https://openalex.org/W2070165661","https://openalex.org/W2070543106","https://openalex.org/W2071459968","https://openalex.org/W2071492556","https://openalex.org/W2072041476","https://openalex.org/W2072274697","https://openalex.org/W2073111207","https://openalex.org/W2075213419","https://openalex.org/W2076550025","https://openalex.org/W2079733308","https://openalex.org/W2080537942","https://openalex.org/W2084411662","https://openalex.org/W2085366382","https://openalex.org/W2087675254","https://openalex.org/W2089484944","https://openalex.org/W2089750332","https://openalex.org/W2091837785","https://openalex.org/W2092314195","https://openalex.org/W2092863416","https://openalex.org/W2103692957","https://openalex.org/W2103837216","https://openalex.org/W2116561212","https://openalex.org/W2123838014","https://openalex.org/W2124284324","https://openalex.org/W2124407078","https://openalex.org/W2138728119","https://openalex.org/W2145107163","https://openalex.org/W2151239423","https://openalex.org/W2157747136","https://openalex.org/W2164398262","https://openalex.org/W2496584646","https://openalex.org/W2502062134","https://openalex.org/W4236990651","https://openalex.org/W4237145713","https://openalex.org/W4246515825","https://openalex.org/W4285719527","https://openalex.org/W4293082421","https://openalex.org/W6723798608"],"related_works":["https://openalex.org/W2084244502","https://openalex.org/W1979008745","https://openalex.org/W2056621949","https://openalex.org/W1980211413","https://openalex.org/W2023876377","https://openalex.org/W2065944858","https://openalex.org/W6923532601","https://openalex.org/W2023341761","https://openalex.org/W2071459968","https://openalex.org/W2095190187"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}