{"id":"https://openalex.org/W1998564950","doi":"https://doi.org/10.1055/s-0028-1084623","title":"High throughput semi-automated extraction method for the creation of a collection from microbial fermentations of fungi and Actinomycetes","display_name":"High throughput semi-automated extraction method for the creation of a collection from microbial fermentations of fungi and Actinomycetes","publication_year":2008,"publication_date":"2008-07-01","ids":{"openalex":"https://openalex.org/W1998564950","doi":"https://doi.org/10.1055/s-0028-1084623","mag":"1998564950"},"language":"en","primary_location":{"id":"doi:10.1055/s-0028-1084623","doi":"https://doi.org/10.1055/s-0028-1084623","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0028-1084623","pdf_url":null,"source":{"id":"https://openalex.org/S39653451","display_name":"Planta Medica","issn_l":"0032-0943","issn":["0032-0943","1439-0221"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Planta Medica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068716769","display_name":"Jos\u00e9 Rub\u00e9n Tormo","orcid":"https://orcid.org/0000-0001-6984-2941","observed_orcids":["https://orcid.org/0000-0001-6984-2941"]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"JR Tormo","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064385162","display_name":"N Tabanera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"N Tabanera","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033316416","display_name":"Donald V. Conway","orcid":"https://orcid.org/0000-0003-2583-1313","observed_orcids":["https://orcid.org/0000-0003-2583-1313"]},"institutions":[{"id":"https://openalex.org/I1285764155","display_name":"Merck & Co., Inc., Rahway, NJ, USA (United States)","ror":"https://ror.org/02891sr49","country_code":"US","type":"company","lineage":["https://openalex.org/I1285764155"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D Conway","raw_affiliation_strings":["Research operations, Merck & Co. 126 E. Lincoln Avenue, P.O. Box 2000, New Jersey, USA","Co. 126 E. Lincoln Avenue, P.O. Box 2000, New Jersey, USA","Research operations, Merck &amp"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research operations, Merck & Co. 126 E. Lincoln Avenue, P.O. Box 2000, New Jersey, USA","institution_ids":["https://openalex.org/I1285764155"]},{"raw_affiliation_string":"Co. 126 E. Lincoln Avenue, P.O. Box 2000, New Jersey, USA","institution_ids":[]},{"raw_affiliation_string":"Research operations, Merck &amp","institution_ids":["https://openalex.org/I1285764155"]}]},{"author_position":"middle","author":{"id":null,"display_name":"P Ramos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"P Ramos","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"A Redondo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"A Redondo","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076983385","display_name":"A. Fillola","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"A Fillola","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013643471","display_name":"MJ Gregorio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"MJ Gregorio","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046766934","display_name":"V\u00edctor Rojas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"V Rojas","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113201337","display_name":"O. Salazar","orcid":"https://orcid.org/0000-0003-2284-4952","observed_orcids":["https://orcid.org/0000-0003-2284-4952"]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"O Salazar","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"J Collado","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"J Collado","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031888544","display_name":"Gerald F. Bills","orcid":"https://orcid.org/0000-0003-2352-8417","observed_orcids":["https://orcid.org/0000-0003-2352-8417"]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"G Bills","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044224553","display_name":"Olga Genilloud","orcid":"https://orcid.org/0000-0002-4202-1219","observed_orcids":["https://orcid.org/0000-0002-4202-1219"]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"O Genilloud","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090732329","display_name":"Fernando Pel\u00e1ez","orcid":"https://orcid.org/0000-0002-4861-586X","observed_orcids":["https://orcid.org/0000-0002-4861-586X"]},"institutions":[{"id":"https://openalex.org/I4210144418","display_name":"MSD (Spain)","ror":"https://ror.org/04thqez65","country_code":"ES","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210144418"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"F Pel\u00e1ez","raw_affiliation_strings":["CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","28027 Madrid, Spain","CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp & Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38; 28027 Madrid, Spain","institution_ids":["https://openalex.org/I4210144418"]},{"raw_affiliation_string":"28027 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"CIBE (Centro de Investigaci\u00f3n B\u00e1sica), Merck Sharp &amp","institution_ids":[]},{"raw_affiliation_string":"Dohme de Espa\u00f1a S.A. Josefa Valc\u00e1rcel, 38","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10372687,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"74","issue":"09","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1507","display_name":"Fluid Flow and Transfer Processes"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13128","display_name":"Chromatography in Natural Products","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-throughput-extraction","display_name":"high-throughput extraction","score":0.6919999718666077},{"id":"https://openalex.org/keywords/semi-automated-extraction","display_name":"semi-automated extraction","score":0.8600000143051147},{"id":"https://openalex.org/keywords/fungi","display_name":"fungi","score":0.5519999861717224},{"id":"https://openalex.org/keywords/actinomycetes","display_name":"actinomycetes","score":0.9990000128746033},{"id":"https://openalex.org/keywords/microbial-fermentation","display_name":"microbial fermentation","score":0.6669999957084656},{"id":"https://openalex.org/keywords/osmac","display_name":"OSMAC","score":0.8330000042915344},{"id":"https://openalex.org/keywords/secondary-metabolites","display_name":"secondary metabolites","score":0.9380000233650208},{"id":"https://openalex.org/keywords/antibiotics","display_name":"antibiotics","score":0.7059999704360962},{"id":"https://openalex.org/keywords/natural-product-library","display_name":"natural product library","score":0.6520000100135803},{"id":"https://openalex.org/keywords/microtiter-plates","display_name":"microplates","score":0.8579999804496765},{"id":"https://openalex.org/keywords/liquid-handling-robot","display_name":"liquid handling robot","score":0.5989999771118164},{"id":"https://openalex.org/keywords/sample-management","display_name":"sample management","score":0.48899999260902405}],"concepts":[{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.7071154117584229},{"id":"https://openalex.org/C175605896","wikidata":"https://www.wikidata.org/wiki/Q39833","display_name":"Microorganism","level":3,"score":0.6357283592224121},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.6041318774223328},{"id":"https://openalex.org/C4725764","wikidata":"https://www.wikidata.org/wiki/Q844704","display_name":"Extraction (chemistry)","level":2,"score":0.5541073679924011},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.48696812987327576},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4550403952598572},{"id":"https://openalex.org/C157764524","wikidata":"https://www.wikidata.org/wiki/Q1383412","display_name":"Throughput","level":3,"score":0.42133277654647827},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.3912571668624878},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3681454658508301},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3677974343299866},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.21607714891433716},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.17201095819473267},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1449708640575409},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1106487512588501},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07366180419921875},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.0},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-0028-1084623","doi":"https://doi.org/10.1055/s-0028-1084623","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0028-1084623","pdf_url":null,"source":{"id":"https://openalex.org/S39653451","display_name":"Planta Medica","issn_l":"0032-0943","issn":["0032-0943","1439-0221"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Planta Medica","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5925999879837036,"id":"https://metadata.un.org/sdg/12","display_name":"Responsible consumption and production"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2415835236","https://openalex.org/W6884298952","https://openalex.org/W2007055380","https://openalex.org/W2966247563","https://openalex.org/W3160617089","https://openalex.org/W4411917881","https://openalex.org/W2899359457","https://openalex.org/W7214797626","https://openalex.org/W2087228545","https://openalex.org/W1980002600"],"abstract_inverted_index":{"The":[0,41,104,227],"'one":[1],"strain-many":[2],"compounds'":[3],"(OSMAC)":[4],"is":[5,259],"a":[6,50,62,78,148,194,248,253],"validated":[7],"approach":[8],"for":[9,53,83,119,155,224,235,247],"maximizing":[10],"the":[11,23,31,39,56,67,84,134,138,140,142,182,207,219,237],"potential":[12],"chemical":[13],"diversity":[14],"of":[15,25,33,43,58,69,88,107,144,221,231,239,252,255],"secondary":[16,145],"metabolites":[17,70],"and":[18,37,86,92,122,125,176,210,229,245],"antibiotics":[19],"from":[20,61,90,213,243],"microorganisms.":[21],"Increasing":[22],"number":[24,106],"fermentation":[26,241],"conditions":[27],"per":[28],"strain":[29,64],"raises":[30],"probability":[32],"detecting":[34],"bioactive":[35],"compounds":[36],"maximizes":[38],"investment.":[40],"use":[42,220],"nutritional":[44],"arrays,":[45],"including":[46],"environmental":[47],"factors,":[48],"constitutes":[49],"possible":[51],"solution":[52,191],"turn":[54],"on":[55,101,133],"expression":[57],"biosynthetic":[59],"pathways":[60],"given":[63],"by":[65,110,192],"increasing":[66],"spectrum":[68],"that":[71,202],"it":[72],"can":[73],"produce.":[74],"Since":[75],"October":[76],"2006,":[77],"new":[79,195],"High":[80,249],"Throughput":[81,250],"platform":[82],"preparation":[85,130],"evaluation":[87],"extracts":[89,172],"fungi":[91,244],"actinomycetes":[93,246],"has":[94],"been":[95],"developed":[96],"in":[97,151,160,173,189,197,205],"our":[98,117,152,190,200],"lab":[99],"based":[100,132],"this":[102,111,232],"approach.":[103],"high":[105],"fermentations":[108],"generated":[109],"technique":[112],"(up":[113],"to":[114,180],"20,000/month)":[115],"challenged":[116],"ability":[118],"an":[120],"efficient":[121],"semi-automated":[123,233],"extraction":[124,238],"sample":[126],"management.":[127],"Prior":[128],"extract":[129,225],"strategies":[131],"premise,":[135],"'the":[136],"higher":[137,141],"biomass":[139],"quantity":[143],"metabolites'":[146],"had":[147,166],"serious":[149],"impact":[150],"automation":[153],"possibilities":[154],"handling":[156,164],"highly":[157],"parallel":[158],"micro-fermentations":[159],"multiwell":[161,174,214],"plates.":[162],"Liquid":[163],"robots":[165],"many":[167],"different":[168],"incompatibilities":[169],"with":[170,199],"direct":[171,211],"plates,":[175],"presented":[177],"significant":[178],"obstacles":[179,186],"attaining":[181],"desired":[183],"throughput.":[184],"These":[185],"were":[187],"overcome":[188],"designing":[193],"system":[196,234],"collaboration":[198],"engineers":[201],"would":[203],"allow,":[204],"theory,":[206],"solvent":[208],"dispensing":[209],"pipetting":[212],"plates":[215],"as":[216,218],"well":[217],"disposable":[222],"tips":[223],"handling.":[226],"design":[228],"implementation":[230],"performing":[236],"miniaturized":[240],"broths":[242],"creation":[251],"Library":[254],"Natural":[256],"Products":[257],"Extracts":[258],"described.":[260]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}