{"id":"https://openalex.org/W1998549446","doi":"https://doi.org/10.1289/ehp.10165","title":"Variations in Phytoestrogen Content between Different Mill Dates of the Same Diet Produces Significant Differences in the Time of Vaginal Opening in CD-1 Mice and F344 Rats but Not in CD Sprague-Dawley Rats","display_name":"Variations in Phytoestrogen Content between Different Mill Dates of the Same Diet Produces Significant Differences in the Time of Vaginal Opening in CD-1 Mice and F344 Rats but Not in CD Sprague-Dawley Rats","publication_year":2007,"publication_date":"2007-09-21","ids":{"openalex":"https://openalex.org/W1998549446","doi":"https://doi.org/10.1289/ehp.10165","mag":"1998549446","pmid":"https://pubmed.ncbi.nlm.nih.gov/18087589","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2137112"},"language":"en","primary_location":{"id":"doi:10.1289/ehp.10165","doi":"https://doi.org/10.1289/ehp.10165","is_oa":true,"landing_page_url":"https://doi.org/10.1289/ehp.10165","pdf_url":null,"source":{"id":"https://openalex.org/S10446503","display_name":"Environmental Health Perspectives","issn_l":"0091-6765","issn":["0091-6765","1552-9924"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319799","host_organization_name":"National Institute of Environmental Health Sciences","host_organization_lineage":["https://openalex.org/P4310319799","https://openalex.org/P4310316754"],"host_organization_lineage_names":["National Institute of Environmental Health Sciences","National Institutes of Health"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Health Perspectives","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1289/ehp.10165","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064849020","display_name":"Julius E. Thigpen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Julius E. Thigpen","raw_affiliation_strings":["Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036804110","display_name":"Kenneth D.R. Setchell","orcid":"https://orcid.org/0000-0001-9147-0136","observed_orcids":["https://orcid.org/0000-0001-9147-0136"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth D.R. Setchell","raw_affiliation_strings":["Department of Pathology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA","Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA","Department of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA","institution_ids":["https://openalex.org/I1285204247"]},{"raw_affiliation_string":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA","institution_ids":["https://openalex.org/I63135867"]},{"raw_affiliation_string":"Department of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA","institution_ids":["https://openalex.org/I1285204247","https://openalex.org/I63135867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060177430","display_name":"Elizabeth Padilla\u2010Banks","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth Padilla-Banks","raw_affiliation_strings":["Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108432966","display_name":"Joseph K. Haseman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph K. Haseman","raw_affiliation_strings":["Biostatistics Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028420827","display_name":"Hannah E. Saunders","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hannah E. Saunders","raw_affiliation_strings":["Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018327873","display_name":"Gordon F. Caviness","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gordon F. Caviness","raw_affiliation_strings":["Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110254923","display_name":"Grace E. Kissling","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Grace E. Kissling","raw_affiliation_strings":["Biostatistics Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048038921","display_name":"Mary G. Grant","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary G. Grant","raw_affiliation_strings":["Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063204515","display_name":"Diane B. Forsythe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diane B. Forsythe","raw_affiliation_strings":["Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comparative Medicine Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5064849020"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":{"value":4500,"currency":"USD","value_usd":4500},"fwci":3.3044,"has_fulltext":false,"cited_by_count":70,"citation_normalized_percentile":{"value":0.91031853,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"115","issue":"12","first_page":"1717","last_page":"1726"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11318","display_name":"Phytoestrogen effects and research","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11318","display_name":"Phytoestrogen effects and research","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.1696999967098236,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.007300000172108412,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phytoestrogens","display_name":"phytoestrogens","score":0.968999981880188},{"id":"https://openalex.org/keywords/endocrine-disruptors","display_name":"endocrine disruptors","score":0.8009999990463257},{"id":"https://openalex.org/keywords/estrogenic-activity","display_name":"estrogenic activity","score":0.7070000171661377},{"id":"https://openalex.org/keywords/cd-1-mice","display_name":"ICR mice","score":0.8899999856948853},{"id":"https://openalex.org/keywords/fischer-344-rats","display_name":"F344 rats","score":0.9909999966621399},{"id":"https://openalex.org/keywords/sprague-dawley-rats","display_name":"Sprague-Dawley rats","score":0.9179999828338623},{"id":"https://openalex.org/keywords/daidzein","display_name":"daidzein","score":0.9309999942779541},{"id":"https://openalex.org/keywords/genistein","display_name":"genistein","score":1.0},{"id":"https://openalex.org/keywords/metabolizable-energy","display_name":"metabolizable energy","score":0.824999988079071},{"id":"https://openalex.org/keywords/ain-76a-diet","display_name":"AIN-76A diet","score":0.8619999885559082},{"id":"https://openalex.org/keywords/vaginal-cytology","display_name":"vaginal cytology","score":0.33399999141693115}],"concepts":[{"id":"https://openalex.org/C2778270713","wikidata":"https://www.wikidata.org/wiki/Q414496","display_name":"Phytoestrogens","level":3,"score":0.9536104202270508},{"id":"https://openalex.org/C2778298627","wikidata":"https://www.wikidata.org/wiki/Q415957","display_name":"Genistein","level":2,"score":0.9058582782745361},{"id":"https://openalex.org/C2780955279","wikidata":"https://www.wikidata.org/wiki/Q408732","display_name":"Daidzein","level":3,"score":0.6845616698265076},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6133760809898376},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5687166452407837},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.5431318879127502},{"id":"https://openalex.org/C2779705811","wikidata":"https://www.wikidata.org/wiki/Q412519","display_name":"Isoflavones","level":2,"score":0.5145180225372314},{"id":"https://openalex.org/C2778914748","wikidata":"https://www.wikidata.org/wiki/Q10850","display_name":"Rodent","level":2,"score":0.5075918436050415},{"id":"https://openalex.org/C2778355148","wikidata":"https://www.wikidata.org/wiki/Q908865","display_name":"Coumestrol","level":4,"score":0.4921066164970398},{"id":"https://openalex.org/C104488531","wikidata":"https://www.wikidata.org/wiki/Q864212","display_name":"Bioassay","level":2,"score":0.4708554148674011},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.4157394766807556},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.410102516412735},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38460782170295715},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.2697749733924866},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2545761168003082},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005247","descriptor_name":"Feeding Behavior","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007529","descriptor_name":"Isoflavones","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007529","descriptor_name":"Isoflavones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011916","descriptor_name":"Rats, Inbred F344","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014621","descriptor_name":"Vagina","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019833","descriptor_name":"Genistein","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D019833","descriptor_name":"Genistein","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D048789","descriptor_name":"Phytoestrogens","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D048789","descriptor_name":"Phytoestrogens","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1289/ehp.10165","doi":"https://doi.org/10.1289/ehp.10165","is_oa":true,"landing_page_url":"https://doi.org/10.1289/ehp.10165","pdf_url":null,"source":{"id":"https://openalex.org/S10446503","display_name":"Environmental Health Perspectives","issn_l":"0091-6765","issn":["0091-6765","1552-9924"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319799","host_organization_name":"National Institute of Environmental Health Sciences","host_organization_lineage":["https://openalex.org/P4310319799","https://openalex.org/P4310316754"],"host_organization_lineage_names":["National Institute of Environmental Health Sciences","National Institutes of Health"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Health Perspectives","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2137112","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2137112","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environ Health Perspect","raw_type":"Text"},{"id":"pmid:18087589","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18087589","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental health perspectives","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1289/ehp.10165","doi":"https://doi.org/10.1289/ehp.10165","is_oa":true,"landing_page_url":"https://doi.org/10.1289/ehp.10165","pdf_url":null,"source":{"id":"https://openalex.org/S10446503","display_name":"Environmental Health Perspectives","issn_l":"0091-6765","issn":["0091-6765","1552-9924"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319799","host_organization_name":"National Institute of Environmental Health Sciences","host_organization_lineage":["https://openalex.org/P4310319799","https://openalex.org/P4310316754"],"host_organization_lineage_names":["National Institute of Environmental Health Sciences","National Institutes of Health"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Health Perspectives","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W2512104","https://openalex.org/W48364373","https://openalex.org/W207953396","https://openalex.org/W1925715381","https://openalex.org/W1963742461","https://openalex.org/W1976392695","https://openalex.org/W1983301469","https://openalex.org/W1986138749","https://openalex.org/W1992665822","https://openalex.org/W1996918646","https://openalex.org/W2003621067","https://openalex.org/W2005144938","https://openalex.org/W2019449921","https://openalex.org/W2023426241","https://openalex.org/W2035028595","https://openalex.org/W2044005041","https://openalex.org/W2047557027","https://openalex.org/W2054673992","https://openalex.org/W2054932840","https://openalex.org/W2058997806","https://openalex.org/W2060531928","https://openalex.org/W2074132268","https://openalex.org/W2077343690","https://openalex.org/W2077874527","https://openalex.org/W2078715315","https://openalex.org/W2080205469","https://openalex.org/W2089828318","https://openalex.org/W2103368550","https://openalex.org/W2121563365","https://openalex.org/W2134085082","https://openalex.org/W2140801633","https://openalex.org/W2141791604","https://openalex.org/W2142289087","https://openalex.org/W2166138367","https://openalex.org/W2404879753","https://openalex.org/W2411114388","https://openalex.org/W2414526878"],"related_works":["https://openalex.org/W7095128228","https://openalex.org/W2404879753","https://openalex.org/W2140801633","https://openalex.org/W7097797545","https://openalex.org/W2005144938","https://openalex.org/W2512104","https://openalex.org/W1983301469","https://openalex.org/W2035028595","https://openalex.org/W7097507935","https://openalex.org/W2142289087"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,84,149,175,209],"optimum":[2],"test":[3,71],"diet":[4,117,229],"and":[5,24,47,61,65,77,98,141],"rodent":[6,21],"species/strain":[7],"for":[8,203],"evaluating":[9,204],"endocrine-disrupting":[10],"compounds":[11],"(EDCs)":[12],"are":[13],"critical.":[14],"OBJECTIVES:":[15],"We":[16],"conducted":[17],"studies":[18],"to":[19,68,181,238],"evaluate":[20],"species":[22],"sensitivity":[23,241],"the":[25,34,115,134,143,161,166,186,190,195,200,216,240],"effects":[26,211],"of":[27,36,79,86,122,151,171,207,212,218,242],"diets":[28,95,103],"varying":[29],"in":[30,40,91,108,130,138,146,153],"phytoestrogen":[31,162],"content":[32,163],"on":[33,56,63,215],"time":[35,78,85,121,150,217],"vaginal":[37],"opening":[38],"(VO)":[39],"CD-1":[41,131,191],"mice,":[42,132],"Fischer":[43],"344":[44],"(F344)":[45],"rats,":[46,140],"CD":[48],"Sprague-Dawley":[49],"(S-D)":[50],"rats.":[51,110,148],"METHODS:":[52],"Mice":[53],"were":[54,81,113],"weaned":[55],"postnatal":[57],"day":[58],"(PND)":[59],"15":[60],"rats":[62,93,155],"PND19":[64],"randomly":[66],"assigned":[67],"control":[69],"or":[70,189],"diets.":[72,173],"Body":[73],"weights,":[74],"food":[75],"consumption,":[76],"VO":[80,87,107,123,152],"recorded.":[82],"RESULTS:":[83],"was":[88,124,156],"significantly":[89,125],"advanced":[90,126],"F344":[92,139,154,187],"fed":[94,114],"containing":[96,230],"daidzein":[97],"genistein,":[99,120],"whereas":[100],"these":[101],"same":[102],"did":[104],"not":[105,199],"advance":[106],"S-D":[109,147,176,196],"When":[111],"animals":[112],"AIN-76A":[116],"spiked":[118],"with":[119,160,165,185],"at":[127,133,142],"all":[128],"doses":[129,137],"two":[135],"highest":[136,144],"dose":[145],"more":[157],"highly":[158],"correlated":[159],"than":[164],"total":[167],"metabolizable":[168],"energy":[169],"(ME)":[170],"12":[172],"CONCLUSIONS:":[174],"rat":[177,188,197],"is":[178,198],"less":[179],"sensitive":[180],"dietary":[182,213],"phytoestrogens":[183,214],"compared":[184],"mouse,":[192],"suggesting":[193],"that":[194,224],"ideal":[201],"model":[202],"estrogenic":[205,243],"activity":[206],"EDCs.":[208],"profound":[210],"VO,":[219],"an":[220],"estrogen-sensitive":[221],"marker,":[222],"indicate":[223],"a":[225,231],"standardized":[226],"open-formula":[227],"phytoestrogen-free":[228],"low":[232],"ME":[233],"level":[234],"should":[235],"be":[236],"used":[237],"optimize":[239],"bioassays.":[244]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}