{"id":"https://openalex.org/W1998520223","doi":"https://doi.org/10.1111/j.1939-1676.2006.tb02835.x","title":"Canine Mast Cell Tumors: Correlation of Apoptosis and Proliferation Markers with Prognosis","display_name":"Canine Mast Cell Tumors: Correlation of Apoptosis and Proliferation Markers with Prognosis","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W1998520223","doi":"https://doi.org/10.1111/j.1939-1676.2006.tb02835.x","mag":"1998520223","pmid":"https://pubmed.ncbi.nlm.nih.gov/16496935"},"language":"en","primary_location":{"id":"doi:10.1111/j.1939-1676.2006.tb02835.x","doi":"https://doi.org/10.1111/j.1939-1676.2006.tb02835.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1939-1676.2006.tb02835.x","pdf_url":null,"source":{"id":"https://openalex.org/S69093139","display_name":"Journal of Veterinary Internal Medicine","issn_l":"0891-6640","issn":["0891-6640","1939-1676"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Veterinary Internal Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1939-1676.2006.tb02835.x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057320173","display_name":"Timothy J. Scase","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335290417","display_name":"Animal Health Trust","ror":"https://ror.org/04npk0q16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1335290417"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Timothy J Scase","raw_affiliation_strings":["Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","institution_ids":["https://openalex.org/I1335290417"]},{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom","institution_ids":["https://openalex.org/I1335290417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113641153","display_name":"David S. Edwards","orcid":"https://orcid.org/0000-0002-5670-087X","observed_orcids":["https://orcid.org/0000-0002-5670-087X"]},"institutions":[{"id":"https://openalex.org/I1335290417","display_name":"Animal Health Trust","ror":"https://ror.org/04npk0q16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1335290417"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David Edwards","raw_affiliation_strings":["Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","institution_ids":["https://openalex.org/I1335290417"]},{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom","institution_ids":["https://openalex.org/I1335290417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104040934","display_name":"Jodi Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335290417","display_name":"Animal Health Trust","ror":"https://ror.org/04npk0q16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1335290417"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jodi Miller","raw_affiliation_strings":["Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","institution_ids":["https://openalex.org/I1335290417"]},{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom","institution_ids":["https://openalex.org/I1335290417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048297938","display_name":"William Henley","orcid":"https://orcid.org/0000-0001-6273-2619","observed_orcids":["https://orcid.org/0000-0001-6273-2619"]},"institutions":[{"id":"https://openalex.org/I1335290417","display_name":"Animal Health Trust","ror":"https://ror.org/04npk0q16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1335290417"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"William Henley","raw_affiliation_strings":["Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","institution_ids":["https://openalex.org/I1335290417"]},{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom","institution_ids":["https://openalex.org/I1335290417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046660383","display_name":"Ken C. Smith","orcid":"https://orcid.org/0000-0002-4861-7048","observed_orcids":["https://orcid.org/0000-0002-4861-7048"]},"institutions":[{"id":"https://openalex.org/I1335290417","display_name":"Animal Health Trust","ror":"https://ror.org/04npk0q16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1335290417"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ken Smith","raw_affiliation_strings":["Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","institution_ids":["https://openalex.org/I1335290417"]},{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom","institution_ids":["https://openalex.org/I1335290417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112793751","display_name":"Anthony S. Blunden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335290417","display_name":"Animal Health Trust","ror":"https://ror.org/04npk0q16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1335290417"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anthony Blunden","raw_affiliation_strings":["Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","institution_ids":["https://openalex.org/I1335290417"]},{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom","institution_ids":["https://openalex.org/I1335290417"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065159932","display_name":"Sue Murphy","orcid":"https://orcid.org/0000-0003-2057-1460","observed_orcids":["https://orcid.org/0000-0003-2057-1460"]},"institutions":[{"id":"https://openalex.org/I1335290417","display_name":"Animal Health Trust","ror":"https://ror.org/04npk0q16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1335290417"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sue Murphy","raw_affiliation_strings":["Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park , Kentford, Newmarket,","institution_ids":["https://openalex.org/I1335290417"]},{"raw_affiliation_string":"Oncology Research Group, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom","institution_ids":["https://openalex.org/I1335290417"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5057320173"],"corresponding_institution_ids":["https://openalex.org/I1335290417"],"apc_list":{"value":2000,"currency":"USD","value_usd":2000},"apc_paid":null,"fwci":17.8664,"has_fulltext":false,"cited_by_count":179,"citation_normalized_percentile":{"value":0.99817629,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"20","issue":"1","first_page":"151","last_page":"151"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11580","display_name":"Veterinary Medicine and Surgery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/canine-mast-cell-tumors","display_name":"canine mast cell tumors","score":0.8820000290870667},{"id":"https://openalex.org/keywords/cutaneous-mast-cell-tumor","display_name":"cutaneous mast cell tumor","score":0.925000011920929},{"id":"https://openalex.org/keywords/ki-67","display_name":"Ki-67","score":0.8550000190734863},{"id":"https://openalex.org/keywords/proliferating-cell-nuclear-antigen","display_name":"proliferating cell nuclear antigen","score":0.9079999923706055},{"id":"https://openalex.org/keywords/survivin","display_name":"survivin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/agnors","display_name":"AgNORs","score":0.7450000047683716},{"id":"https://openalex.org/keywords/apoptosis-markers","display_name":"apoptosis markers","score":0.5659999847412109},{"id":"https://openalex.org/keywords/proliferation-markers","display_name":"cell proliferation markers","score":0.8949999809265137},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9020000100135803},{"id":"https://openalex.org/keywords/survival-prediction","display_name":"survival prediction","score":0.6809999942779541},{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.9700000286102295}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8346690535545349},{"id":"https://openalex.org/C2777751288","wikidata":"https://www.wikidata.org/wiki/Q409106","display_name":"Ki-67","level":3,"score":0.6157647371292114},{"id":"https://openalex.org/C2775975398","wikidata":"https://www.wikidata.org/wiki/Q906904","display_name":"Survivin","level":3,"score":0.5858075618743896},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.5678069591522217},{"id":"https://openalex.org/C34688535","wikidata":"https://www.wikidata.org/wiki/Q418732","display_name":"Proliferating cell nuclear antigen","level":3,"score":0.5675680041313171},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.5428450703620911},{"id":"https://openalex.org/C2777286243","wikidata":"https://www.wikidata.org/wiki/Q5591926","display_name":"Grading (engineering)","level":2,"score":0.5391059517860413},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.4700445234775543},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46346819400787354},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4615151584148407},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4542853832244873},{"id":"https://openalex.org/C10515644","wikidata":"https://www.wikidata.org/wiki/Q543310","display_name":"Survival analysis","level":2,"score":0.4535932242870331},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.15718775987625122},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.12851274013519287},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07927802205085754},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004283","descriptor_name":"Dog Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D004283","descriptor_name":"Dog Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004283","descriptor_name":"Dog Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009687","descriptor_name":"Nuclear Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009687","descriptor_name":"Nuclear Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012515","descriptor_name":"Mast-Cell Sarcoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012515","descriptor_name":"Mast-Cell Sarcoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012515","descriptor_name":"Mast-Cell Sarcoma","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018809","descriptor_name":"Proliferating Cell Nuclear Antigen","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018809","descriptor_name":"Proliferating Cell Nuclear Antigen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D034961","descriptor_name":"Antigens, Nuclear","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D034961","descriptor_name":"Antigens, Nuclear","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051034","descriptor_name":"Inhibitor of Apoptosis Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051034","descriptor_name":"Inhibitor of Apoptosis Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1111/j.1939-1676.2006.tb02835.x","doi":"https://doi.org/10.1111/j.1939-1676.2006.tb02835.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1939-1676.2006.tb02835.x","pdf_url":null,"source":{"id":"https://openalex.org/S69093139","display_name":"Journal of Veterinary Internal Medicine","issn_l":"0891-6640","issn":["0891-6640","1939-1676"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Veterinary Internal Medicine","raw_type":"journal-article"},{"id":"doi:10.1892/0891-6640(2006)20[151:cmctco]2.0.co;2","doi":"https://doi.org/10.1892/0891-6640(2006)20[151:cmctco]2.0.co;2","is_oa":true,"landing_page_url":"https://doi.org/10.1892/0891-6640(2006)20[151:cmctco]2.0.co;2","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1939-1676.2006.tb02835.x","source":{"id":"https://openalex.org/S69093139","display_name":"Journal of Veterinary Internal Medicine","issn_l":"0891-6640","issn":["0891-6640","1939-1676"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Veterinary Internal Medicine","raw_type":"journal-article"},{"id":"pmid:16496935","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16496935","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of veterinary internal medicine","raw_type":"Journal Article"},{"id":"pmh:oai:figshare.com:article/29757569","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/journal_contribution/Canine_mast_cell_tumors_Correlation_of_apoptosis_and_proliferation_markers_with_prognosis/29757569","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:ore.exeter.ac.uk:10871/37694","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10871/37694","pdf_url":null,"source":{"id":"https://openalex.org/S4306401998","display_name":"Open Research Exeter (University of Exeter)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I23923803","host_organization_name":"University of Exeter","host_organization_lineage":["https://openalex.org/I23923803"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:researchonline.rvc.ac.uk:186","doi":null,"is_oa":true,"landing_page_url":"http://researchonline.rvc.ac.uk/id/eprint/186/","pdf_url":null,"source":{"id":"https://openalex.org/S4306402069","display_name":"RVC Research Online (Royal Veterinary College)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I133836048","host_organization_name":"Royal Veterinary College","host_organization_lineage":["https://openalex.org/I133836048"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1892/0891-6640(2006)20[151:cmctco]2.0.co;2","doi":"https://doi.org/10.1892/0891-6640(2006)20[151:cmctco]2.0.co;2","is_oa":true,"landing_page_url":"https://doi.org/10.1892/0891-6640(2006)20[151:cmctco]2.0.co;2","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1939-1676.2006.tb02835.x","source":{"id":"https://openalex.org/S69093139","display_name":"Journal of Veterinary Internal Medicine","issn_l":"0891-6640","issn":["0891-6640","1939-1676"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Veterinary Internal Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1998520223.pdf","grobid_xml":"https://content.openalex.org/works/W1998520223.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W10588058","https://openalex.org/W28394576","https://openalex.org/W1570622790","https://openalex.org/W1893157084","https://openalex.org/W1968379106","https://openalex.org/W1970085289","https://openalex.org/W1979177187","https://openalex.org/W1983274306","https://openalex.org/W1988052793","https://openalex.org/W2001017617","https://openalex.org/W2011338138","https://openalex.org/W2014033278","https://openalex.org/W2027158717","https://openalex.org/W2031068182","https://openalex.org/W2035523654","https://openalex.org/W2049856484","https://openalex.org/W2064580048","https://openalex.org/W2073098562","https://openalex.org/W2076298841","https://openalex.org/W2104980443","https://openalex.org/W2113839914","https://openalex.org/W2116199102","https://openalex.org/W2117088031","https://openalex.org/W2119636956","https://openalex.org/W2121176844","https://openalex.org/W2124633824","https://openalex.org/W2124838635","https://openalex.org/W2129733618","https://openalex.org/W2132813978","https://openalex.org/W2134452094","https://openalex.org/W2152234318","https://openalex.org/W2161278525","https://openalex.org/W2176099369","https://openalex.org/W2257506447","https://openalex.org/W2395107753","https://openalex.org/W2417081853","https://openalex.org/W2440063932"],"related_works":["https://openalex.org/W2141521133","https://openalex.org/W28394576","https://openalex.org/W4376640370","https://openalex.org/W2115528629","https://openalex.org/W4390672330","https://openalex.org/W2035465201","https://openalex.org/W2144255226","https://openalex.org/W57646655","https://openalex.org/W4280651921","https://openalex.org/W7101018955"],"abstract_inverted_index":{"The":[0,136,171,234],"Patnaik":[1,109,242],"histologic":[2],"grading":[3],"system":[4],"is":[5,22],"commonly":[6],"used":[7,239],"to":[8,240],"predict":[9],"the":[10,86],"behavior":[11],"of":[12,57,70,128],"cutaneous":[13,72],"mast":[14],"cell":[15,46],"tumors":[16],"(MCTs)":[17],"in":[18,34],"dogs,":[19],"but":[20],"it":[21],"less":[23,153],"useful":[24],"for":[25,43,74,130,144,175,231],"grade":[26,110,133,147,178,243],"2":[27,134,148,179,244,247],"MCTs":[28,149,180,245],"because":[29],"they":[30],"exhibit":[31],"considerable":[32],"variation":[33],"biological":[35],"behavior.":[36],"In":[37],"this":[38],"retrospective":[39],"study,":[40],"immunohistochemical":[41],"staining":[42,56],"Ki-67,":[44],"proliferating":[45],"nuclear":[47],"antigen":[48],"(PCNA),":[49],"and":[50,52,95,111,140,150,159,165,181,190,196,211,225],"survivin":[51,212],"a":[53,125],"standardized":[54],"argyrophilic":[55],"nucleolar":[58],"organizer":[59],"regions":[60],"(AgNOR)":[61],"protocol":[62],"were":[63,79,105,156,187],"performed":[64],"on":[65],"121":[66],"archived":[67],"paraffin-embedded":[68],"specimens":[69],"canine":[71,232],"MCTs,":[73],"which":[75],"clinical":[76],"follow-up":[77],"data":[78],"available.":[80],"Cox":[81],"regression":[82],"models":[83],"indicated":[84],"that":[85,220],"Ki-67":[87,116,120,151,182,226,235],"score":[88,98,121,213,224,227,236],"(hazard":[89,99],"ratio,":[90,100],"1.92;":[91],"P":[92,102],"<":[93,103],".001)":[94,104],"mean":[96,222],"AgNOR":[97,223],"2.57;":[101],"significantly":[106],"associated":[107],"with":[108,132,146,177,249],"survival":[112,129,142,173,200,210,253],"time.":[113],"A":[114],"binary":[115],"variable":[117],"(cutoff":[118],"point":[119],"=":[122],"1.8)":[123],"was":[124,207],"significant":[126,205],"predictor":[127],"dogs":[131,145,176],"MCTs.":[135,233],"estimated":[137],"1-,":[138],"2-,":[139],"3-year":[141],"probabilities":[143,174],"scores":[152,183],"than":[154,185],"1.8":[155,186],"0.92,":[157],"0.86,":[158],"0.77,":[160],"respectively":[161,192],"(SEs,":[162,193],"0.08,":[163],"0.14,":[164],"0.23,":[166],"respectively;":[167,198],"median":[168,199],"not":[169],"estimable).":[170],"corresponding":[172],"higher":[184],"0.43,":[188],"0.21,":[189,191],"0.19,":[194],"0.18,":[195,197],"time,":[201],"395":[202],"days).":[203],"No":[204],"association":[206],"identified":[208],"between":[209],"or":[214],"PCNA":[215],"score.":[216],"This":[217],"study":[218],"shows":[219],"both":[221],"are":[228],"prognostic":[229],"markers":[230],"can":[237],"be":[238],"divide":[241],"into":[246],"groups":[248],"markedly":[250],"different":[251],"expected":[252],"times.":[254]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}