{"id":"https://openalex.org/W1998466332","doi":"https://doi.org/10.1002/bjs.1800611018","title":"The treatment of advanced bladder cancer with sensitized pig lymphocytes","display_name":"The treatment of advanced bladder cancer with sensitized pig lymphocytes","publication_year":1974,"publication_date":"1974-10-01","ids":{"openalex":"https://openalex.org/W1998466332","doi":"https://doi.org/10.1002/bjs.1800611018","mag":"1998466332","pmid":"https://pubmed.ncbi.nlm.nih.gov/4416547"},"language":"en","primary_location":{"id":"doi:10.1002/bjs.1800611018","doi":"https://doi.org/10.1002/bjs.1800611018","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bjs.1800611018","pdf_url":null,"source":{"id":"https://openalex.org/S61740008","display_name":"British journal of surgery","issn_l":"0007-1323","issn":["0007-1323","1365-2168"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of British Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109059623","display_name":"Roger C. L. Feneley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R C L Feneley","raw_affiliation_strings":["Departments of Surgery, Radiotherapy and Pathology, University of Bristol"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Radiotherapy and Pathology, University of Bristol","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":null,"display_name":"H Eckert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"H Eckert","raw_affiliation_strings":["Departments of Surgery, Radiotherapy and Pathology, University of Bristol"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Radiotherapy and Pathology, University of Bristol","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076583426","display_name":"Athol G. Riddell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A G Riddell","raw_affiliation_strings":["Departments of Surgery, Radiotherapy and Pathology, University of Bristol"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Radiotherapy and Pathology, University of Bristol","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111691695","display_name":"M O Symes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M O Symes","raw_affiliation_strings":["Departments of Surgery, Radiotherapy and Pathology, University of Bristol"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Radiotherapy and Pathology, University of Bristol","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029750687","display_name":"Colin R. Tribe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"C R Tribe","raw_affiliation_strings":["Departments of Surgery, Radiotherapy and Pathology, University of Bristol"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery, Radiotherapy and Pathology, University of Bristol","institution_ids":["https://openalex.org/I36234482"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I36234482"],"apc_list":{"value":3797,"currency":"GBP","value_usd":5007},"apc_paid":null,"fwci":5.8,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.95203741,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"61","issue":"10","first_page":"825","last_page":"827"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12996","display_name":"Bacterial Cancer Therapy","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/advanced-bladder-cancer","display_name":"advanced bladder cancer","score":0.9549999833106995},{"id":"https://openalex.org/keywords/urothelial-carcinoma","display_name":"urothelial carcinoma","score":0.9399999976158142},{"id":"https://openalex.org/keywords/pig-lymphocytes","display_name":"pig lymphocytes","score":0.7789999842643738},{"id":"https://openalex.org/keywords/lymphocyte-sensitization","display_name":"lymphocyte sensitization","score":0.6470000147819519},{"id":"https://openalex.org/keywords/arterial-infusion","display_name":"arterial infusion","score":0.5730000138282776},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.45899999141693115},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.8159999847412109},{"id":"https://openalex.org/keywords/immunotherapy","display_name":"immunotherapy","score":0.5299999713897705}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9658061265945435},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.6333132386207581},{"id":"https://openalex.org/C2778065480","wikidata":"https://www.wikidata.org/wiki/Q2501186","display_name":"Transitional cell carcinoma","level":4,"score":0.5990926027297974},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.5782393217086792},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.532534122467041},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.531059741973877},{"id":"https://openalex.org/C2779762690","wikidata":"https://www.wikidata.org/wiki/Q9382","display_name":"Urinary bladder","level":2,"score":0.5255203247070312},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.509159505367279},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.4439789652824402},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.4393455982208252},{"id":"https://openalex.org/C2780352672","wikidata":"https://www.wikidata.org/wiki/Q504775","display_name":"Bladder cancer","level":3,"score":0.42692744731903076},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3879006803035736},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.34739136695861816},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3425607979297638},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.332415372133255},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3012763261795044}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D004804","descriptor_name":"Eosinophils","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006417","descriptor_name":"Hematuria","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007263","descriptor_name":"Infusions, Parenteral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D009368","descriptor_name":"Neoplasm Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011838","descriptor_name":"Radiation-Sensitizing Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014183","descriptor_name":"Transplantation, Heterologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014567","descriptor_name":"Urography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017710","descriptor_name":"Lymphocyte Transfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/bjs.1800611018","doi":"https://doi.org/10.1002/bjs.1800611018","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bjs.1800611018","pdf_url":null,"source":{"id":"https://openalex.org/S61740008","display_name":"British journal of surgery","issn_l":"0007-1323","issn":["0007-1323","1365-2168"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of British Surgery","raw_type":"journal-article"},{"id":"pmid:4416547","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4416547","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The British journal of surgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":3,"referenced_works":["https://openalex.org/W1981445681","https://openalex.org/W2020177958","https://openalex.org/W2031832535"],"related_works":["https://openalex.org/W1520888709","https://openalex.org/W2089056886","https://openalex.org/W2396220264","https://openalex.org/W1597307775","https://openalex.org/W2031832535","https://openalex.org/W1984778140","https://openalex.org/W7207985823","https://openalex.org/W2743742935","https://openalex.org/W1979005175","https://openalex.org/W2304470312"],"abstract_inverted_index":{"Abstract":[0],"Twenty-five":[1],"patients":[2,44,62,86],"with":[3],"transitional":[4],"cell":[5,34,64],"carcinoma":[6],"of":[7,16,27,52,75],"the":[8,23,28,37,50],"urinary":[9],"bladder":[10],"have":[11],"been":[12],"treated":[13],"by":[14,71],"infusion":[15,35,65],"sensitized":[17],"pig":[18,33,45,63],"lymph":[19],"node":[20],"cells":[21,46],"into":[22],"arterial":[24],"blood":[25],"supply":[26],"tumour.":[29],"In":[30,77],"7":[31,43],"cases":[32],"was":[36,66],"only":[38],"treatment,":[39],"in":[40,49,60],"a":[41,53],"further":[42],"were":[47],"given":[48],"treatment":[51,80],"major":[54],"tumour":[55],"recurrence":[56],"following":[57],"radiotherapy":[58],"and":[59,84,91],"11":[61],"followed":[67],"after":[68],"4-8":[69],"weeks":[70],"an":[72],"attenuated":[73],"course":[74],"radiotherapy.":[76],"these":[78],"three":[79],"groups":[81],"2,":[82],"3":[83],"9":[85],"respectively":[87],"obtained":[88],"clinical":[89],"benefit":[90],"biopsy":[92],"showed":[93],"histological":[94],"change.":[95]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}