{"id":"https://openalex.org/W1998452142","doi":"https://doi.org/10.1097/ccm.0b013e318165314b","title":"Temporal changes in management and outcome of septic shock in patients with malignancies in the intensive care unit*","display_name":"Temporal changes in management and outcome of septic shock in patients with malignancies in the intensive care unit*","publication_year":2008,"publication_date":"2008-03-01","ids":{"openalex":"https://openalex.org/W1998452142","doi":"https://doi.org/10.1097/ccm.0b013e318165314b","mag":"1998452142","pmid":"https://pubmed.ncbi.nlm.nih.gov/18431262"},"language":"en","primary_location":{"id":"doi:10.1097/ccm.0b013e318165314b","doi":"https://doi.org/10.1097/ccm.0b013e318165314b","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ccm.0b013e318165314b","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049019312","display_name":"Fr\u00e9d\u00e9ric P\u00e8ne","orcid":"https://orcid.org/0000-0003-3639-3849","observed_orcids":["https://orcid.org/0000-0003-3639-3849"]},"institutions":[{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fr\u00e9d\u00e9ric P\u00e8ne","raw_affiliation_strings":["Medical Intensive Care Unit, Cochin Hospital, AP-HP, Paris, France. frederic.pene@cch.aphp.fr","France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Intensive Care Unit, Cochin Hospital, AP-HP, Paris, France. frederic.pene@cch.aphp.fr","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049167550","display_name":"St\u00e9phanie Percheron","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210141964"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"St\u00e9phanie Percheron","raw_affiliation_strings":["Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210141964","https://openalex.org/I4387156284"]},{"raw_affiliation_string":"From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108126286","display_name":"Virginie Lemiale","orcid":"https://orcid.org/0000-0002-1736-747X","observed_orcids":["https://orcid.org/0000-0002-1736-747X"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210141964"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Virginie Lemiale","raw_affiliation_strings":["Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210141964","https://openalex.org/I4387156284"]},{"raw_affiliation_string":"From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060396702","display_name":"Vivian Viallon","orcid":"https://orcid.org/0000-0002-9799-4421","observed_orcids":["https://orcid.org/0000-0002-9799-4421"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210141964"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Vivian Viallon","raw_affiliation_strings":["Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210141964","https://openalex.org/I4387156284"]},{"raw_affiliation_string":"From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109867837","display_name":"Yann-\u00c9rick Claessens","orcid":"https://orcid.org/0000-0001-7506-3063","observed_orcids":["https://orcid.org/0000-0001-7506-3063"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210141964"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Yann-Erick Claessens","raw_affiliation_strings":["Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210141964","https://openalex.org/I4387156284"]},{"raw_affiliation_string":"From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007588924","display_name":"Sophie Marqu\u00e9","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210141964"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sophie Marqu\u00e9","raw_affiliation_strings":["Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210141964","https://openalex.org/I4387156284"]},{"raw_affiliation_string":"From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069387998","display_name":"Julien Charpentier","orcid":"https://orcid.org/0000-0003-3117-1235","observed_orcids":["https://orcid.org/0000-0003-3117-1235"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210141964"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Julien Charpentier","raw_affiliation_strings":["Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210141964","https://openalex.org/I4387156284"]},{"raw_affiliation_string":"From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001670387","display_name":"Derek C. Angus","orcid":"https://orcid.org/0000-0002-7026-5181","observed_orcids":["https://orcid.org/0000-0002-7026-5181"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210141964"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Derek C. Angus","raw_affiliation_strings":["Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210141964","https://openalex.org/I4387156284"]},{"raw_affiliation_string":"From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065027400","display_name":"Alain Cariou","orcid":"https://orcid.org/0000-0003-3258-4672","observed_orcids":["https://orcid.org/0000-0003-3258-4672"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210141964"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Alain Cariou","raw_affiliation_strings":["Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210141964","https://openalex.org/I4387156284"]},{"raw_affiliation_string":"From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073851208","display_name":"Jean\u2010Daniel Chiche","orcid":"https://orcid.org/0000-0002-6433-6254","observed_orcids":["https://orcid.org/0000-0002-6433-6254"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210141964"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Daniel Chiche","raw_affiliation_strings":["Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210141964","https://openalex.org/I4387156284"]},{"raw_affiliation_string":"From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"France","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108821314","display_name":"Jean Paul Mira","orcid":"https://orcid.org/0000-0001-8121-3769","observed_orcids":["https://orcid.org/0000-0001-8121-3769"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210092774","display_name":"H\u00f4pital Cochin","ror":"https://ror.org/00ph8tk69","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210092774","https://openalex.org/I4210097159","https://openalex.org/I4210124464"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210141964","display_name":"Institut Cochin","ror":"https://ror.org/051sk4035","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210141964"]},{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Paul Mira","raw_affiliation_strings":["Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular Biology, Cochin Institute, Paris-Descartes University, INSERM U567, CNRS (UMR 8104), Paris, France (FP, YEC, JDC, JPM)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210141964","https://openalex.org/I4387156284"]},{"raw_affiliation_string":"From the Medical Intensive Care Unit (FP, SP, VL, SM, JC, DCA, AC, JDC, JPM), Department of Biostatistics (VV), and Emergency Department (YEC), Cochin Hospital, AP-HP, Paris, France","institution_ids":["https://openalex.org/I4210092774","https://openalex.org/I4210097159"]},{"raw_affiliation_string":"France","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":14.6381,"has_fulltext":false,"cited_by_count":203,"citation_normalized_percentile":{"value":0.99157079,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"36","issue":"3","first_page":"690","last_page":"696"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12172","display_name":"Neutropenia and Cancer Infections","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11623","display_name":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/septic-shock","display_name":"septic shock","score":1.0},{"id":"https://openalex.org/keywords/cancer-patients","display_name":"cancer patients","score":0.902999997138977},{"id":"https://openalex.org/keywords/intensive-care-unit","display_name":"intensive care unit","score":0.5350000262260437},{"id":"https://openalex.org/keywords/survival-outcomes","display_name":"survival outcomes","score":0.5130000114440918},{"id":"https://openalex.org/keywords/low-dose-glucocorticoids","display_name":"low-dose glucocorticoids","score":0.8870000243186951},{"id":"https://openalex.org/keywords/intensive-insulin-therapy","display_name":"intensive insulin therapy","score":0.972000002861023},{"id":"https://openalex.org/keywords/renal-replacement-therapy","display_name":"renal replacement therapy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hematologic-malignancies","display_name":"hematologic malignancies","score":0.8289999961853027},{"id":"https://openalex.org/keywords/solid-tumors","display_name":"solid tumors","score":0.9580000042915344},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.6769999861717224},{"id":"https://openalex.org/keywords/temporal-trends-in-care","display_name":"temporal trends in care","score":0.6620000004768372}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9566241502761841},{"id":"https://openalex.org/C2777628635","wikidata":"https://www.wikidata.org/wiki/Q1765564","display_name":"Septic shock","level":3,"score":0.8390195965766907},{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.6505422592163086},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.6291384100914001},{"id":"https://openalex.org/C2781300812","wikidata":"https://www.wikidata.org/wiki/Q178061","display_name":"Shock (circulatory)","level":2,"score":0.518344521522522},{"id":"https://openalex.org/C148220186","wikidata":"https://www.wikidata.org/wiki/Q7111912","display_name":"Outcome (game theory)","level":2,"score":0.5098971128463745},{"id":"https://openalex.org/C2987404301","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care","level":2,"score":0.4259323477745056},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.33625632524490356},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.3232859969139099},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15764844417572021},{"id":"https://openalex.org/C144237770","wikidata":"https://www.wikidata.org/wiki/Q747534","display_name":"Mathematical economics","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007362","descriptor_name":"Intensive Care Units","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012772","descriptor_name":"Shock, Septic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D012772","descriptor_name":"Shock, Septic","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D012772","descriptor_name":"Shock, Septic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/ccm.0b013e318165314b","doi":"https://doi.org/10.1097/ccm.0b013e318165314b","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ccm.0b013e318165314b","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},{"id":"pmid:18431262","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18431262","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical care medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1794971901","https://openalex.org/W1898928487","https://openalex.org/W1917557897","https://openalex.org/W1940869776","https://openalex.org/W1970461520","https://openalex.org/W1972350167","https://openalex.org/W1980717583","https://openalex.org/W1993389721","https://openalex.org/W1994367184","https://openalex.org/W2003947509","https://openalex.org/W2007671328","https://openalex.org/W2022906676","https://openalex.org/W2027774931","https://openalex.org/W2043436644","https://openalex.org/W2049927822","https://openalex.org/W2055988708","https://openalex.org/W2056303881","https://openalex.org/W2062308880","https://openalex.org/W2067724073","https://openalex.org/W2072776551","https://openalex.org/W2087203965","https://openalex.org/W2106534536","https://openalex.org/W2111117400","https://openalex.org/W2115285670","https://openalex.org/W2128349740","https://openalex.org/W2130322800","https://openalex.org/W2130521018","https://openalex.org/W2145577370","https://openalex.org/W2149525313","https://openalex.org/W2160691650","https://openalex.org/W2163814324","https://openalex.org/W2165325086","https://openalex.org/W2322121630","https://openalex.org/W2550507245","https://openalex.org/W2597070792","https://openalex.org/W3216465316","https://openalex.org/W4245690870"],"related_works":["https://openalex.org/W4211221145","https://openalex.org/W2011674443","https://openalex.org/W4390794701","https://openalex.org/W2037329728","https://openalex.org/W2955911032","https://openalex.org/W2335517162","https://openalex.org/W2953826729","https://openalex.org/W2751011546","https://openalex.org/W4283733527","https://openalex.org/W4414263662"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Septic":[1,101],"shock":[2,18,34,80,102,116],"is":[3],"a":[4,63,138,269],"severe,":[5],"often":[6],"terminal,":[7],"complication":[8],"of":[9,45,114,125,128,142,258,272],"malignancy.":[10],"For":[11],"patients":[12,72,106,218,253,259,273],"without":[13],"malignancy,":[14],"outcome":[15,31,248],"from":[16,32],"septic":[17,33,79,115,261],"has":[19,35],"improved":[20,37],"with":[21,41,78,159,260],"new":[22,283],"advances":[23],"in":[24,62,104,107,111,146,217,229,237,241,249,277],"care.":[25],"We":[26],"wished":[27],"to":[28,43,82,255,268,275],"explore":[29],"whether":[30],"similarly":[36],"for":[38,209,286],"cancer":[39,71,252],"patients,":[40],"regard":[42],"implementation":[44],"recent":[46,148],"adjuvant":[47,126],"therapies.":[48],"DESIGN:":[49],"An":[50],"8-yr":[51],"retrospective":[52],"observational":[53],"study.":[54],"SETTING:":[55],"A":[56],"24-bed":[57],"medical":[58],"intensive":[59,84,134,165,195,231],"care":[60,85,166,196,232,279],"unit":[61,86,197,233],"university":[64],"hospital.":[65],"PATIENTS:":[66],"Patients":[67],"were":[68,153,172],"238":[69],"consecutive":[70,89],"(solid":[73],"tumors":[74],"or":[75],"hematologic":[76],"malignancies)":[77],"admitted":[81],"the":[83,118,147,160,230,256,278],"within":[87],"two":[88,119],"4-yr":[90,162],"periods:":[91],"1998-2001":[92,108],"and":[93,109,133,137,168,185,201,274,280],"2002-2005.":[94,112],"INTERVENTIONS:":[95],"None.":[96],"MEASUREMENTS":[97],"AND":[98],"MAIN":[99],"RESULTS:":[100],"occurred":[103],"90":[105],"148":[110],"Management":[113],"between":[117,199],"periods":[120],"mostly":[121],"differed":[122],"by":[123],"emergence":[124],"therapies":[127],"sepsis":[129],"(mainly":[130],"low-dose":[131],"glucocorticoids)":[132],"insulin":[135],"therapy":[136,145,225],"more":[139],"frequent":[140],"use":[141],"renal":[143,223],"replacement":[144,224],"period.":[149],"Short-term":[150],"survival":[151,170,213,235],"rates":[152,171],"significantly":[154],"higher":[155],"during":[156,226],"2002-2005":[157,238],"compared":[158],"previous":[161],"period:":[163],"28-day,":[164],"unit,":[167],"hospital":[169],"47.3%":[173],"vs.":[174,180,187,239],"27.8%":[175],"(p":[176,182,189],"=":[177,183,190],".003),":[178],"41.2%":[179],"26.7%":[181],".02),":[184],"36.5%":[186],"21.1%":[188],".01),":[191],"respectively.":[192],"After":[193],"adjustment,":[194],"admission":[198],"2002":[200],"2005":[202],"was":[203,214],"an":[204],"independent":[205],"favorable":[206],"prognostic":[207],"factor":[208],"short-term":[210],"outcome.":[211],"Improved":[212,247],"mainly":[215],"observed":[216],"who":[219],"did":[220],"not":[221],"require":[222],"their":[227],"stay":[228],"(hospital":[234],"65%":[236],"21.4%":[240],"1998-2001,":[242],"p":[243],"<":[244],".001).":[245],"CONCLUSIONS:":[246],"critically":[250],"ill":[251],"extended":[254],"subgroup":[257],"shock.":[262],"This":[263],"might":[264],"be":[265],"ascribed":[266],"both":[267],"better":[270],"selection":[271],"improvements":[276],"management,":[281],"including":[282],"therapeutic":[284],"strategies":[285],"sepsis.":[287]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":20},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":18},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}