{"id":"https://openalex.org/W1998446404","doi":"https://doi.org/10.1074/jbc.m509707200","title":"Specific Recognition of the Collagen Triple Helix by Chaperone HSP47","display_name":"Specific Recognition of the Collagen Triple Helix by Chaperone HSP47","publication_year":2005,"publication_date":"2005-12-03","ids":{"openalex":"https://openalex.org/W1998446404","doi":"https://doi.org/10.1074/jbc.m509707200","mag":"1998446404","pmid":"https://pubmed.ncbi.nlm.nih.gov/16326708"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.m509707200","doi":"https://doi.org/10.1074/jbc.m509707200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m509707200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/jbc.m509707200","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061696959","display_name":"Takaki Koide","orcid":"https://orcid.org/0000-0002-0681-6874","observed_orcids":["https://orcid.org/0000-0002-0681-6874"]},"institutions":[{"id":"https://openalex.org/I114838220","display_name":"Niigata University of Pharmacy and Medical and Life Sciences","ror":"https://ror.org/00dnbtf70","country_code":"JP","type":"education","lineage":["https://openalex.org/I114838220"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Takaki Koide","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 950-2081, Japan. koi@niigata-pharm.ac.hp","Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 950-2081, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 950-2081, Japan. koi@niigata-pharm.ac.hp","institution_ids":["https://openalex.org/I114838220"]},{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 950-2081, Japan","institution_ids":["https://openalex.org/I114838220"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078661763","display_name":"Shinichi Asada","orcid":"https://orcid.org/0000-0002-7857-8123","observed_orcids":["https://orcid.org/0000-0002-7857-8123"]},"institutions":[{"id":"https://openalex.org/I114838220","display_name":"Niigata University of Pharmacy and Medical and Life Sciences","ror":"https://ror.org/00dnbtf70","country_code":"JP","type":"education","lineage":["https://openalex.org/I114838220"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinichi Asada","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 950-2081, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 950-2081, Japan","institution_ids":["https://openalex.org/I114838220"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028806713","display_name":"Yoshifumi Takahara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I922474255","display_name":"Tokushima University","ror":"https://ror.org/044vy1d05","country_code":"JP","type":"education","lineage":["https://openalex.org/I922474255"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshifumi Takahara","raw_affiliation_strings":["Faculty of Engineering, The University of Tokushima, Tokushima 770-8506, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Engineering, The University of Tokushima, Tokushima 770-8506, Japan","institution_ids":["https://openalex.org/I922474255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112266579","display_name":"Yoshimi Nishikawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114838220","display_name":"Niigata University of Pharmacy and Medical and Life Sciences","ror":"https://ror.org/00dnbtf70","country_code":"JP","type":"education","lineage":["https://openalex.org/I114838220"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshimi Nishikawa","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 950-2081, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 950-2081, Japan","institution_ids":["https://openalex.org/I114838220"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101581468","display_name":"Kazuhiro Nagata","orcid":"https://orcid.org/0000-0001-8894-7431","observed_orcids":["https://orcid.org/0000-0001-8894-7431"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuhiro Nagata","raw_affiliation_strings":["Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8397, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8397, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111531211","display_name":"Kouki Kitagawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114838220","display_name":"Niigata University of Pharmacy and Medical and Life Sciences","ror":"https://ror.org/00dnbtf70","country_code":"JP","type":"education","lineage":["https://openalex.org/I114838220"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kouki Kitagawa","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 950-2081, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 950-2081, Japan","institution_ids":["https://openalex.org/I114838220"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5061696959"],"corresponding_institution_ids":["https://openalex.org/I114838220"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":1.3422,"has_fulltext":false,"cited_by_count":80,"citation_normalized_percentile":{"value":0.76676829,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"281","issue":"6","first_page":"3432","last_page":"3438"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12085","display_name":"Collagen: Extraction and Characterization","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11150","display_name":"Endoplasmic Reticulum Stress and Disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hsp47","display_name":"HSP47","score":0.9819999933242798},{"id":"https://openalex.org/keywords/collagen-triple-helix","display_name":"collagen triple helix","score":0.9819999933242798},{"id":"https://openalex.org/keywords/molecular-chaperones","display_name":"molecular chaperones","score":0.7860000133514404},{"id":"https://openalex.org/keywords/arginine-residues","display_name":"arginine residues","score":0.4569999873638153},{"id":"https://openalex.org/keywords/endoplasmic-reticulum","display_name":"endoplasmic reticulum","score":0.8849999904632568},{"id":"https://openalex.org/keywords/collagen-model-peptides","display_name":"collagen model peptides","score":0.7680000066757202},{"id":"https://openalex.org/keywords/heterotrimeric-collagen","display_name":"heterotrimeric collagen","score":0.6079999804496765}],"concepts":[{"id":"https://openalex.org/C64348721","wikidata":"https://www.wikidata.org/wiki/Q7247456","display_name":"Procollagen peptidase","level":2,"score":0.7388893365859985},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.7018114328384399},{"id":"https://openalex.org/C155181932","wikidata":"https://www.wikidata.org/wiki/Q24768908","display_name":"Collagen helix","level":3,"score":0.6981204748153687},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6733968257904053},{"id":"https://openalex.org/C2775962898","wikidata":"https://www.wikidata.org/wiki/Q5073152","display_name":"Chaperone (clinical)","level":2,"score":0.6504665613174438},{"id":"https://openalex.org/C10919887","wikidata":"https://www.wikidata.org/wiki/Q7843514","display_name":"Triple helix","level":2,"score":0.6092742085456848},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5465667843818665},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.4577644169330597},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.418793261051178},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3827563524246216},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.37132027745246887},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3436933755874634},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.2396022379398346},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17558637261390686},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06740736961364746},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001120","descriptor_name":"Arginine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001667","descriptor_name":"Binding, Competitive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002845","descriptor_name":"Chromatography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002942","descriptor_name":"Circular Dichroism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D003432","descriptor_name":"Cross-Linking Reagents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004721","descriptor_name":"Endoplasmic Reticulum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013053","descriptor_name":"Spectrophotometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014466","descriptor_name":"Ultraviolet Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018832","descriptor_name":"Molecular Chaperones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020349","descriptor_name":"Surface Plasmon Resonance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050958","descriptor_name":"HSP47 Heat-Shock Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1074/jbc.m509707200","doi":"https://doi.org/10.1074/jbc.m509707200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m509707200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:16326708","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16326708","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1074/jbc.m509707200","doi":"https://doi.org/10.1074/jbc.m509707200","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m509707200","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323325","display_name":"University of Tokushima","ror":"https://ror.org/044vy1d05"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W857428898","https://openalex.org/W1481645778","https://openalex.org/W1495528364","https://openalex.org/W1498798237","https://openalex.org/W1513234099","https://openalex.org/W1528567179","https://openalex.org/W1543184164","https://openalex.org/W1580325848","https://openalex.org/W1822769289","https://openalex.org/W1890886311","https://openalex.org/W1965353054","https://openalex.org/W1967879051","https://openalex.org/W1970338434","https://openalex.org/W1972116094","https://openalex.org/W1978014671","https://openalex.org/W1979221090","https://openalex.org/W1994199936","https://openalex.org/W1997718936","https://openalex.org/W2002736874","https://openalex.org/W2005746614","https://openalex.org/W2006343757","https://openalex.org/W2019200461","https://openalex.org/W2022905437","https://openalex.org/W2031757535","https://openalex.org/W2034920774","https://openalex.org/W2041039856","https://openalex.org/W2043825401","https://openalex.org/W2046420403","https://openalex.org/W2055118741","https://openalex.org/W2055269877","https://openalex.org/W2055914451","https://openalex.org/W2058060182","https://openalex.org/W2069836942","https://openalex.org/W2074565288","https://openalex.org/W2083566893","https://openalex.org/W2085394534","https://openalex.org/W2093235355","https://openalex.org/W2099952448","https://openalex.org/W2106662920","https://openalex.org/W2111801168","https://openalex.org/W2114805703","https://openalex.org/W2122860492","https://openalex.org/W2125639937","https://openalex.org/W2137331982","https://openalex.org/W2144284050","https://openalex.org/W2149039469","https://openalex.org/W2162915566","https://openalex.org/W2167161817","https://openalex.org/W2775153111","https://openalex.org/W4233983392"],"related_works":["https://openalex.org/W1967879051","https://openalex.org/W2001473432","https://openalex.org/W1965353054","https://openalex.org/W1972116094","https://openalex.org/W1968669612","https://openalex.org/W2093235355","https://openalex.org/W2557858089","https://openalex.org/W2114805703","https://openalex.org/W3177691960","https://openalex.org/W2150386615"],"abstract_inverted_index":{"The":[0,200],"unique":[1],"folding":[2],"of":[3,14,53,112,117,171,192,207,211],"procollagens":[4],"in":[5,32,47,63,125,174,196],"the":[6,12,50,102,108,145,148,169,175,189,197,205,218],"endoplasmic":[7,24],"reticulum":[8],"is":[9,22],"achieved":[10],"with":[11,147],"assistance":[13],"procollagen-specific":[15],"molecular":[16,38],"chaperones.":[17],"Heat-shock":[18],"protein":[19],"47":[20],"(HSP47)":[21],"an":[23,29,193],"reticulum-resident":[25],"chaperone":[26],"that":[27,57,135,144,214],"plays":[28],"essential":[30],"role":[31],"normal":[33],"procollagen":[34],"folding,":[35],"although":[36],"its":[37,70],"function":[39],"has":[40],"not":[41],"yet":[42],"been":[43],"clarified.":[44],"Recent":[45],"advances":[46],"studies":[48,128],"on":[49],"binding":[51,127,156],"specificity":[52],"HSP47":[54,113,136,163,194],"have":[55],"revealed":[56,134],"Arg":[58,172],"residues":[59,173],"at":[60],"Yaa":[61],"positions":[62],"collagenous":[64,184],"Gly-Xaa-Yaa":[65],"repeats":[66],"are":[67],"critical":[68],"for":[69,162,168],"interactions":[71],"(Koide,":[72],"T.,":[73],"Takahara,":[74],"Y.,":[75],"Asada,":[76],"S.,":[77],"and":[78,91,143,229],"Nagata,":[79],"K.":[80],"(2002)":[81,95],"J.":[82,94,96,234],"Biol.":[83,97,235],"Chem.":[84,98,236],"277,":[85,99],"6178-6182;":[86],"Tasab,":[87],"M.,":[88,228],"Jenkinson,":[89],"L.,":[90],"Bulleid,":[92],"N.":[93],"35007-35012).":[100],"In":[101],"present":[103],"study,":[104],"we":[105],"further":[106],"examined":[107],"client":[109],"recognition":[110],"mechanism":[111],"by":[114],"taking":[115],"advantage":[116],"systems":[118],"employing":[119],"engineered":[120],"collagen":[121],"model":[122,160,210],"peptides.":[123],"First,":[124],"vitro":[126],"using":[129,158,182],"conformationally":[130],"constrained":[131],"collagen-like":[132],"peptides":[133,185],"only":[137],"recognized":[138],"correctly":[139],"folded":[140],"triple":[141,176],"helices":[142],"interaction":[146],"corresponding":[149],"single-chain":[150],"polypeptides":[151],"was":[152],"negligible.":[153],"Second,":[154],"a":[155,165,179,208],"study":[157,181],"heterotrimeric":[159],"clients":[161],"demonstrated":[164],"minimal":[166],"requirement":[167],"number":[170],"helix.":[177],"Finally,":[178],"cross-linking":[180],"photoreactive":[183],"provided":[186],"information":[187],"about":[188],"spatial":[190],"orientation":[191],"molecule":[195],"chaperone-collagen":[198],"complex.":[199],"obtained":[201],"results":[202],"led":[203],"to":[204],"development":[206],"new":[209],"HSP47-collagen":[212],"complexes":[213],"differs":[215],"completely":[216],"from":[217],"previously":[219],"proposed":[220],"\"flying":[221],"capstan":[222],"model\"":[223],"(Dafforn,":[224],"T.":[225],"R.,":[226],"Della,":[227],"Miller,":[230],"A.":[231],"D.":[232],"(2001)":[233],"276,":[237],"49310-49319).":[238]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}