{"id":"https://openalex.org/W1998433472","doi":"https://doi.org/10.1143/apex.4.017001","title":"Development of Label-Free Bioaffinity Sensor Using a Lumped-Constant Microwave Resonator Probe","display_name":"Development of Label-Free Bioaffinity Sensor Using a Lumped-Constant Microwave Resonator Probe","publication_year":2011,"publication_date":"2011-01-05","ids":{"openalex":"https://openalex.org/W1998433472","doi":"https://doi.org/10.1143/apex.4.017001","mag":"1998433472"},"language":"en","primary_location":{"id":"doi:10.1143/apex.4.017001","doi":"https://doi.org/10.1143/apex.4.017001","is_oa":true,"landing_page_url":"https://doi.org/10.1143/apex.4.017001","pdf_url":"https://iopscience.iop.org/article/10.1143/APEX.4.017001/pdf","source":{"id":"https://openalex.org/S54409865","display_name":"Applied Physics Express","issn_l":"1882-0778","issn":["1882-0778","1882-0786"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","norway-1","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311669","host_organization_name":"Institute of Physics","host_organization_lineage":["https://openalex.org/P4310311669"],"host_organization_lineage_names":["Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied Physics Express","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://iopscience.iop.org/article/10.1143/APEX.4.017001/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112153797","display_name":"Noriaki Okazaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]},{"id":"https://openalex.org/I4405285984","display_name":"Research Institute of Electrical Communication, Tohoku University","ror":"https://ror.org/00vbrys56","country_code":"JP","type":"facility","lineage":["https://openalex.org/I201537933","https://openalex.org/I4405285984"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Noriaki Okazaki","raw_affiliation_strings":["Research Institute of Electrical Communication, Tohoku University, Sendai 980-8577, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Electrical Communication, Tohoku University, Sendai 980-8577, Japan","institution_ids":["https://openalex.org/I201537933","https://openalex.org/I4405285984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055740763","display_name":"Taito Nishino","orcid":"https://orcid.org/0000-0001-5298-4353","observed_orcids":["https://orcid.org/0000-0001-5298-4353"]},"institutions":[{"id":"https://openalex.org/I4210112703","display_name":"Nissan Chemical Corporation (Japan)","ror":"https://ror.org/01skwyh03","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210112703"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Taito Nishino","raw_affiliation_strings":["Nissan Chemical Industries, Ltd., Funabashi, Chiba 274-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nissan Chemical Industries, Ltd., Funabashi, Chiba 274-8507, Japan","institution_ids":["https://openalex.org/I4210112703"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020777915","display_name":"Toyohiro Chikyow","orcid":"https://orcid.org/0000-0003-3860-4806","observed_orcids":["https://orcid.org/0000-0003-3860-4806"]},"institutions":[{"id":"https://openalex.org/I205401836","display_name":"National Institute for Materials Science","ror":"https://ror.org/026v1ze26","country_code":"JP","type":"facility","lineage":["https://openalex.org/I205401836"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toyohiro Chikyow","raw_affiliation_strings":["Advanced Electronic Materials Center, National Institute for Materials Science, Tsukuba, Ibaraki 305-0044, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Electronic Materials Center, National Institute for Materials Science, Tsukuba, Ibaraki 305-0044, Japan","institution_ids":["https://openalex.org/I205401836"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005011124","display_name":"Yasuo Cho","orcid":"https://orcid.org/0000-0002-4783-5852","observed_orcids":["https://orcid.org/0000-0002-4783-5852"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]},{"id":"https://openalex.org/I4405285984","display_name":"Research Institute of Electrical Communication, Tohoku University","ror":"https://ror.org/00vbrys56","country_code":"JP","type":"facility","lineage":["https://openalex.org/I201537933","https://openalex.org/I4405285984"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuo Cho","raw_affiliation_strings":["Research Institute of Electrical Communication, Tohoku University, Sendai 980-8577, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Electrical Communication, Tohoku University, Sendai 980-8577, Japan","institution_ids":["https://openalex.org/I201537933","https://openalex.org/I4405285984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2365,"currency":"USD","value_usd":2365},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"4","issue":"1","first_page":"017001","last_page":"017001"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11607","display_name":"Microwave and Dielectric Measurement Techniques","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11607","display_name":"Microwave and Dielectric Measurement Techniques","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11160","display_name":"Acoustic Wave Resonator Technologies","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12270","display_name":"Microwave-Assisted Synthesis and Applications","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gold-probe","display_name":"gold probe","score":0.7710000276565552},{"id":"https://openalex.org/keywords/anti-albumin-antibodies","display_name":"anti-albumin antibodies","score":0.7509999871253967},{"id":"https://openalex.org/keywords/resonant-frequency-shift","display_name":"resonant frequency shift","score":0.9070000052452087},{"id":"https://openalex.org/keywords/dielectric-constant-change","display_name":"dielectric constant change","score":0.7839999794960022},{"id":"https://openalex.org/keywords/flow-cell","display_name":"flow cell","score":0.5830000042915344}],"concepts":[{"id":"https://openalex.org/C97126364","wikidata":"https://www.wikidata.org/wiki/Q349669","display_name":"Resonator","level":2,"score":0.81025230884552},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.6320779323577881},{"id":"https://openalex.org/C44838205","wikidata":"https://www.wikidata.org/wiki/Q127995","display_name":"Microwave","level":2,"score":0.6007992029190063},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.569832980632782},{"id":"https://openalex.org/C133386390","wikidata":"https://www.wikidata.org/wiki/Q184996","display_name":"Dielectric","level":2,"score":0.5633427500724792},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4996168613433838},{"id":"https://openalex.org/C139210041","wikidata":"https://www.wikidata.org/wiki/Q2145840","display_name":"Resonance (particle physics)","level":2,"score":0.4596312940120697},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.43983733654022217},{"id":"https://openalex.org/C186397771","wikidata":"https://www.wikidata.org/wiki/Q5759014","display_name":"Microwave cavity","level":3,"score":0.4110924005508423},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.39822909235954285},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.39709675312042236},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.2684336006641388},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.20940697193145752},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.2067529559135437},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09788504242897034},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09241145849227905},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0874718725681305},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C109214941","wikidata":"https://www.wikidata.org/wiki/Q18334","display_name":"Particle physics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1143/apex.4.017001","doi":"https://doi.org/10.1143/apex.4.017001","is_oa":true,"landing_page_url":"https://doi.org/10.1143/apex.4.017001","pdf_url":"https://iopscience.iop.org/article/10.1143/APEX.4.017001/pdf","source":{"id":"https://openalex.org/S54409865","display_name":"Applied Physics Express","issn_l":"1882-0778","issn":["1882-0778","1882-0786"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","norway-1","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311669","host_organization_name":"Institute of Physics","host_organization_lineage":["https://openalex.org/P4310311669"],"host_organization_lineage_names":["Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied Physics Express","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1143/apex.4.017001","doi":"https://doi.org/10.1143/apex.4.017001","is_oa":true,"landing_page_url":"https://doi.org/10.1143/apex.4.017001","pdf_url":"https://iopscience.iop.org/article/10.1143/APEX.4.017001/pdf","source":{"id":"https://openalex.org/S54409865","display_name":"Applied Physics Express","issn_l":"1882-0778","issn":["1882-0778","1882-0786"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","norway-1","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311669","host_organization_name":"Institute of Physics","host_organization_lineage":["https://openalex.org/P4310311669"],"host_organization_lineage_names":["Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied Physics Express","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1998433472.pdf","grobid_xml":"https://content.openalex.org/works/W1998433472.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W166269271","https://openalex.org/W1963566562","https://openalex.org/W1964182620","https://openalex.org/W1967818013","https://openalex.org/W1969304525","https://openalex.org/W1970018836","https://openalex.org/W1983318669","https://openalex.org/W1984277447","https://openalex.org/W1987416224","https://openalex.org/W1997471263","https://openalex.org/W2038190173","https://openalex.org/W2043026524","https://openalex.org/W2049098650","https://openalex.org/W2064519336","https://openalex.org/W2071794555","https://openalex.org/W2081875004","https://openalex.org/W2121249010","https://openalex.org/W2142794584","https://openalex.org/W2146269609","https://openalex.org/W2149214991","https://openalex.org/W2170125941","https://openalex.org/W2318747422"],"related_works":["https://openalex.org/W4367293928","https://openalex.org/W2745115018","https://openalex.org/W2054226609","https://openalex.org/W7141643975","https://openalex.org/W4414474126","https://openalex.org/W6908562536","https://openalex.org/W2131051605","https://openalex.org/W2027325315","https://openalex.org/W2118666477","https://openalex.org/W2144240574"],"abstract_inverted_index":{"A":[0,12],"novel":[1],"label-free":[2],"bioaffinity":[3],"sensor":[4,49],"using":[5],"a":[6,16,39,90],"lumped-constant":[7],"microwave":[8],"resonator":[9,35],"was":[10,31,79],"developed.":[11],"gold":[13],"probe":[14],"with":[15,93],"spherical":[17],"tip":[18],"immobilizing":[19],"anti-chicken":[20],"egg":[21],"albumin":[22,26],"antibody":[23,27],"or":[24],"anti-human":[25],"on":[28],"its":[29,54],"surface":[30],"connected":[32],"to":[33,42,81],"the":[34,44,59,65,74,82],"and":[36],"inserted":[37],"into":[38],"flow":[40],"cell":[41],"monitor":[43],"target":[45,55],"antigen":[46,56,66,77,94],"binding.":[47],"The":[48,68],"showed":[50,89],"specific":[51],"sensitivity":[52],"against":[53],"evidenced":[57],"by":[58],"change":[60,83],"of":[61,76,84],"resonance":[62],"frequency":[63,70],"after":[64],"injection.":[67],"large":[69],"shift":[71],"observed":[72],"during":[73],"injection":[75],"solution":[78,85],"ascribed":[80],"dielectric":[86],"constant":[87],"which":[88],"systematic":[91],"increase":[92],"concentration.":[95]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-24T09:50:30.924529","created_date":"2016-06-24T00:00:00"}