{"id":"https://openalex.org/W1998415568","doi":"https://doi.org/10.1046/j.1365-2559.1996.247295.x","title":"A clinical, histopathological and flow cytometric study of 149 complete moles, 146 partial moles and 107 non\u2010molar hydropic abortions","display_name":"A clinical, histopathological and flow cytometric study of 149 complete moles, 146 partial moles and 107 non\u2010molar hydropic abortions","publication_year":1996,"publication_date":"1996-02-01","ids":{"openalex":"https://openalex.org/W1998415568","doi":"https://doi.org/10.1046/j.1365-2559.1996.247295.x","mag":"1998415568","pmid":"https://pubmed.ncbi.nlm.nih.gov/8834517"},"language":"en","primary_location":{"id":"doi:10.1046/j.1365-2559.1996.247295.x","doi":"https://doi.org/10.1046/j.1365-2559.1996.247295.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2559.1996.247295.x","pdf_url":null,"source":{"id":"https://openalex.org/S14376486","display_name":"Histopathology","issn_l":"0309-0167","issn":["0309-0167","1365-2559"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histopathology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113581018","display_name":"Fernando J Paradinas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"F.J. PARADINAS","raw_affiliation_strings":["Department of Histopathology, Charing Cross Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histopathology, Charing Cross Hospital, London, UK","institution_ids":["https://openalex.org/I2802369498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046135003","display_name":"Patrick J Browne","orcid":"https://orcid.org/0000-0001-6022-0839","observed_orcids":["https://orcid.org/0000-0001-6022-0839"]},"institutions":[{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P. BROWNE","raw_affiliation_strings":["Department of Histopathology, Charing Cross Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histopathology, Charing Cross Hospital, London, UK","institution_ids":["https://openalex.org/I2802369498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086902560","display_name":"Rosemary Ann Fisher","orcid":"https://orcid.org/0000-0002-2721-8726","observed_orcids":["https://orcid.org/0000-0002-2721-8726"]},"institutions":[{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R.A. FISHER","raw_affiliation_strings":["Department of Histopathology, Charing Cross Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histopathology, Charing Cross Hospital, London, UK","institution_ids":["https://openalex.org/I2802369498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075038086","display_name":"Marianne Foskett","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. FOSKETT","raw_affiliation_strings":["Department of Histopathology, Charing Cross Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histopathology, Charing Cross Hospital, London, UK","institution_ids":["https://openalex.org/I2802369498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026768443","display_name":"K D Bagshawe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"K.D. BAGSHAWE","raw_affiliation_strings":["Department of Histopathology, Charing Cross Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histopathology, Charing Cross Hospital, London, UK","institution_ids":["https://openalex.org/I2802369498"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108452347","display_name":"Edward S. Newlands","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"E. NEWLANDS","raw_affiliation_strings":["Department of Histopathology, Charing Cross Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histopathology, Charing Cross Hospital, London, UK","institution_ids":["https://openalex.org/I2802369498"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2802369498"],"apc_list":{"value":4840,"currency":"USD","value_usd":4840},"apc_paid":null,"fwci":9.7504,"has_fulltext":false,"cited_by_count":161,"citation_normalized_percentile":{"value":0.98674596,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"28","issue":"2","first_page":"101","last_page":"109"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12587","display_name":"Gestational Trophoblastic Disease Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12587","display_name":"Gestational Trophoblastic Disease Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/complete-hydatidiform-mole","display_name":"complete hydatidiform mole","score":0.8230000138282776},{"id":"https://openalex.org/keywords/partial-mole","display_name":"partial mole","score":0.9950000047683716},{"id":"https://openalex.org/keywords/hydropic-abortion","display_name":"hydropic abortion","score":0.8190000057220459},{"id":"https://openalex.org/keywords/gestational-trophoblastic-disease","display_name":"gestational trophoblastic disease","score":0.8830000162124634},{"id":"https://openalex.org/keywords/human-chorionic-gonadotropin","display_name":"human chorionic gonadotropin","score":0.8999999761581421},{"id":"https://openalex.org/keywords/maternal-age","display_name":"maternal age","score":0.6069999933242798},{"id":"https://openalex.org/keywords/histopathological-diagnosis","display_name":"histopathological diagnosis","score":0.5080000162124634}],"concepts":[{"id":"https://openalex.org/C2908941940","wikidata":"https://www.wikidata.org/wiki/Q881855","display_name":"Partial Hydatidiform Mole","level":5,"score":0.8423775434494019},{"id":"https://openalex.org/C124815738","wikidata":"https://www.wikidata.org/wiki/Q41509","display_name":"Mole","level":2,"score":0.6016212105751038},{"id":"https://openalex.org/C202271784","wikidata":"https://www.wikidata.org/wiki/Q189218","display_name":"Molar","level":2,"score":0.5529285073280334},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5012454986572266},{"id":"https://openalex.org/C2778165768","wikidata":"https://www.wikidata.org/wiki/Q881855","display_name":"Molar pregnancy","level":4,"score":0.4194064140319824},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28455448150634766},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.2267141044139862},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.18564236164093018},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18033254146575928},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.09218725562095642},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.07304000854492188},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000022","descriptor_name":"Abortion, Spontaneous","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000022","descriptor_name":"Abortion, Spontaneous","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006063","descriptor_name":"Chorionic Gonadotropin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006828","descriptor_name":"Hydatidiform Mole","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006828","descriptor_name":"Hydatidiform Mole","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006828","descriptor_name":"Hydatidiform Mole","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011003","descriptor_name":"Ploidies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014594","descriptor_name":"Uterine Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014594","descriptor_name":"Uterine Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014594","descriptor_name":"Uterine Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1046/j.1365-2559.1996.247295.x","doi":"https://doi.org/10.1046/j.1365-2559.1996.247295.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2559.1996.247295.x","pdf_url":null,"source":{"id":"https://openalex.org/S14376486","display_name":"Histopathology","issn_l":"0309-0167","issn":["0309-0167","1365-2559"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histopathology","raw_type":"journal-article"},{"id":"pmid:8834517","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8834517","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histopathology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1543366482","https://openalex.org/W2057448752","https://openalex.org/W1998298890","https://openalex.org/W2433946939","https://openalex.org/W2422439586","https://openalex.org/W2006991329","https://openalex.org/W2032189727","https://openalex.org/W1985305678","https://openalex.org/W2046111107","https://openalex.org/W2081719946"],"abstract_inverted_index":{"We":[0],"have":[1],"compared":[2],"the":[3,95,177,198,217,248,262],"clinical":[4],"and":[5,17,42,72,78,112,141,147,188,191,210,224,236,241,247,261],"histological":[6],"features":[7],"of":[8,70,94,138,164,226,250],"149":[9],"complete":[10,36,84,102,154,235,264],"moles":[11,16,26,41,58,68,85,103,109,136,151,155,166,183,265],"with":[12,35,39,44,128,134,212,244],"146":[13],"triploid":[14],"partial":[15,40,67,108,135,150,165,237,259],"107":[18],"diploid":[19],"non-molar":[20],"hydropic":[21,45,79,113,129],"abortions":[22,80,204],"initially":[23],"registered":[24],"as":[25,53],"for":[27,49],"human":[28],"chorionic":[29],"gonadotrophin":[30],"(hCG)":[31],"follow-up.":[32],"Forty-one":[33],"patients":[34,127],"moles,":[37],"five":[38],"one":[43],"abortion":[46,114,130],"received":[47],"chemotherapy":[48],"hCG":[50,98,118],"elevations":[51],"interpreted":[52],"persistent":[54],"trophoblastic":[55],"disease.":[56],"Complete":[57,182],"were":[59,62,99,184,205],"aborted":[60],"or":[61,253],"evacuated":[63,266],"significantly":[64,81],"earlier":[65,82,125,148],"than":[66,83,106,131,152],"(means":[69,137],"12.1":[71],"15.4":[73],"weeks;":[74,88],"P":[75,89,144,159],"<":[76,90,145,160],"0.001)":[77,146],"(mean":[86,156],"10.7":[87],"0.005).":[91,161],"The":[92,162],"means":[93],"highest":[96],"recorded":[97],"higher":[100],"in":[101,107,126,132,149,153],"(184,056":[104],"i.v.)":[105,111],"(66,259":[110],"(7942":[115],"i.v.).":[116],"When":[117],"became":[119],"normal":[120],"without":[121],"chemotherapy,":[122],"this":[123],"occurred":[124],"those":[133],"46.7":[139],"days":[140],"62.8":[142],"days;":[143,158],"78.3":[157],"incidence":[163],"was":[167],"comparable":[168],"throughout":[169],"fertile":[170],"years":[171,190,209],"but":[172],"rose":[173],"to":[174,214],"1.9":[175],"times":[176,197,216],"average":[178,199,218],"after":[179,192,200,219],"40":[180,201,220],"years.":[181,202,221],"commoner":[185],"between":[186,234,258],"14":[187],"25":[189,208],"35":[193],"years,":[194],"reaching":[195],"4.8":[196],"Hydropic":[203],"rare":[206],"before":[207,228],"increased":[211,240],"age":[213,246],"12":[215],"Stromal":[222],"karyorrhexis":[223],"shape":[225],"villi,":[227],"they":[229],"become":[230],"hydropic,":[231],"discriminate":[232,257],"well":[233],"mole.":[238],"Hydrops":[239],"vascularity":[242],"decreased":[243],"molar":[245],"presence":[249],"non-hydropic":[251],"villi":[252],"vessels":[254],"did":[255],"not":[256],"mole":[260],"younger":[263],"nowadays.":[267]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}