{"id":"https://openalex.org/W1998409337","doi":"https://doi.org/10.3171/2014.10.jns132370","title":"Wireless control of intraspinal microstimulation in a rodent model of paralysis","display_name":"Wireless control of intraspinal microstimulation in a rodent model of paralysis","publication_year":2014,"publication_date":"2014-12-05","ids":{"openalex":"https://openalex.org/W1998409337","doi":"https://doi.org/10.3171/2014.10.jns132370","mag":"1998409337","pmid":"https://pubmed.ncbi.nlm.nih.gov/25479124","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4457704"},"language":"en","primary_location":{"id":"doi:10.3171/2014.10.jns132370","doi":"https://doi.org/10.3171/2014.10.jns132370","is_oa":true,"landing_page_url":"https://doi.org/10.3171/2014.10.jns132370","pdf_url":"https://thejns.org/downloadpdf/journals/j-neurosurg/123/1/article-p232.pdf","source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://thejns.org/downloadpdf/journals/j-neurosurg/123/1/article-p232.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005585726","display_name":"Peter J. Grahn","orcid":"https://orcid.org/0000-0002-2976-814X","observed_orcids":["https://orcid.org/0000-0002-2976-814X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter J. Grahn","raw_affiliation_strings":["Mayo Graduate School,\u00a0","Mayo Graduate School; Mayo Clinic; Rochester Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Graduate School,\u00a0","institution_ids":[]},{"raw_affiliation_string":"Mayo Graduate School; Mayo Clinic; Rochester Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078418080","display_name":"Kendall H. Lee","orcid":"https://orcid.org/0000-0001-9107-4221","observed_orcids":["https://orcid.org/0000-0001-9107-4221"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kendall H. Lee","raw_affiliation_strings":["Departments of Neurologic Surgery and","Physiology and Biomedical Engineering,","Departments of 2Neurologic Surgery and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Neurologic Surgery and","institution_ids":[]},{"raw_affiliation_string":"Physiology and Biomedical Engineering,","institution_ids":[]},{"raw_affiliation_string":"Departments of 2Neurologic Surgery and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078369195","display_name":"Aimen S. Kasasbeh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aimen Kasasbeh","raw_affiliation_strings":["Departments of Neurologic Surgery and","Department of Neurologic Surgery Mayo Clinic Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Neurologic Surgery and","institution_ids":[]},{"raw_affiliation_string":"Department of Neurologic Surgery Mayo Clinic Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113732517","display_name":"Grant W. Mallory","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Grant W. Mallory","raw_affiliation_strings":["Departments of Neurologic Surgery and","Department of Neurologic Surgery Mayo Clinic Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Neurologic Surgery and","institution_ids":[]},{"raw_affiliation_string":"Department of Neurologic Surgery Mayo Clinic Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069172540","display_name":"Jan T. Hachmann","orcid":"https://orcid.org/0000-0002-0625-6416","observed_orcids":["https://orcid.org/0000-0002-0625-6416"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jan T. Hachmann","raw_affiliation_strings":["Departments of Neurologic Surgery and","Mayo Graduate School,\u00a0","Mayo Clinic Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Neurologic Surgery and","institution_ids":[]},{"raw_affiliation_string":"Mayo Graduate School,\u00a0","institution_ids":[]},{"raw_affiliation_string":"Mayo Clinic Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011605189","display_name":"John R. Dube","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John R. Dube","raw_affiliation_strings":["Departments of Neurologic Surgery and","Department of Neurologic Surgery Mayo Clinic Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Neurologic Surgery and","institution_ids":[]},{"raw_affiliation_string":"Department of Neurologic Surgery Mayo Clinic Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077038357","display_name":"Christopher J. Kimble","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher J. Kimble","raw_affiliation_strings":["Division of Engineering, and","Division of Engineering, Mayo Clinic, Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Engineering, and","institution_ids":[]},{"raw_affiliation_string":"Division of Engineering, Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017183067","display_name":"Darlene Angela Lobel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Darlene A. Lobel","raw_affiliation_strings":["Departments of Neurologic Surgery and","Department of Neurologic Surgery Mayo Clinic Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Neurologic Surgery and","institution_ids":[]},{"raw_affiliation_string":"Department of Neurologic Surgery Mayo Clinic Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071662993","display_name":"Allan J. Bieber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allan Bieber","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, Minnesota","Departments of Neurologic Surgery and","Mayo Graduate School,\u00a0"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Departments of Neurologic Surgery and","institution_ids":[]},{"raw_affiliation_string":"Mayo Graduate School,\u00a0","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055838111","display_name":"Ju Ho Jeong","orcid":"https://orcid.org/0000-0002-6771-9509","observed_orcids":["https://orcid.org/0000-0002-6771-9509"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ju Ho Jeong","raw_affiliation_strings":["Departments of Neurologic Surgery and","Department of Neurologic Surgery Mayo Clinic Rochester, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Neurologic Surgery and","institution_ids":[]},{"raw_affiliation_string":"Department of Neurologic Surgery Mayo Clinic Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028973720","display_name":"Kevin E. Bennet","orcid":"https://orcid.org/0000-0003-1715-878X","observed_orcids":["https://orcid.org/0000-0003-1715-878X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kevin E. Bennet","raw_affiliation_strings":["Departments of Neurologic Surgery and","Division of Engineering, and","Departments of 2Neurologic Surgery and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Neurologic Surgery and","institution_ids":[]},{"raw_affiliation_string":"Division of Engineering, and","institution_ids":[]},{"raw_affiliation_string":"Departments of 2Neurologic Surgery and","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042754834","display_name":"J. Luis Luj\u00e1n","orcid":"https://orcid.org/0000-0003-3496-3932","observed_orcids":["https://orcid.org/0000-0003-3496-3932"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Luis Lujan","raw_affiliation_strings":["Departments of Neurologic Surgery and","Physiology and Biomedical Engineering,","Departments of 2Neurologic Surgery and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Neurologic Surgery and","institution_ids":[]},{"raw_affiliation_string":"Physiology and Biomedical Engineering,","institution_ids":[]},{"raw_affiliation_string":"Departments of 2Neurologic Surgery and","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7214,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.82823292,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"123","issue":"1","first_page":"232","last_page":"242"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.8628000020980835,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.8628000020980835,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.1315000057220459,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10510","display_name":"Stroke Rehabilitation and Recovery","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intraspinal-microstimulation","display_name":"intraspinal microstimulation","score":1.0},{"id":"https://openalex.org/keywords/spinal-cord-injury","display_name":"spinal cord injury","score":0.953000009059906},{"id":"https://openalex.org/keywords/paralysis","display_name":"paralysis","score":0.7429999709129333},{"id":"https://openalex.org/keywords/hindlimb-motor-function","display_name":"hindlimb motor function","score":0.7699999809265137},{"id":"https://openalex.org/keywords/rodent-models","display_name":"rodent models","score":0.6240000128746033},{"id":"https://openalex.org/keywords/functional-recovery","display_name":"functional recovery","score":0.3330000042915344}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8997732400894165},{"id":"https://openalex.org/C2776443511","wikidata":"https://www.wikidata.org/wiki/Q1724687","display_name":"Neurostimulation","level":3,"score":0.8678251504898071},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.7336887121200562},{"id":"https://openalex.org/C2778970358","wikidata":"https://www.wikidata.org/wiki/Q6840343","display_name":"Microstimulation","level":3,"score":0.7286407947540283},{"id":"https://openalex.org/C2778334475","wikidata":"https://www.wikidata.org/wiki/Q1415275","display_name":"Spinal cord injury","level":3,"score":0.6061601638793945},{"id":"https://openalex.org/C51738704","wikidata":"https://www.wikidata.org/wiki/Q5766112","display_name":"Hindlimb","level":2,"score":0.604037880897522},{"id":"https://openalex.org/C44575665","wikidata":"https://www.wikidata.org/wiki/Q1293405","display_name":"Lumbar","level":2,"score":0.4596829414367676},{"id":"https://openalex.org/C2909382400","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Lumbar Spinal Cord","level":3,"score":0.4473664462566376},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.43277308344841003},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.39383482933044434},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3817663788795471},{"id":"https://openalex.org/C140530291","wikidata":"https://www.wikidata.org/wiki/Q1225063","display_name":"Dorsum","level":2,"score":0.3468838930130005},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009068","descriptor_name":"Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010243","descriptor_name":"Paralysis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010243","descriptor_name":"Paralysis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013119","descriptor_name":"Spinal Cord Injuries","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013119","descriptor_name":"Spinal Cord Injuries","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019054","descriptor_name":"Evoked Potentials, Motor","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D023421","descriptor_name":"Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059015","descriptor_name":"Wireless Technology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.3171/2014.10.jns132370","doi":"https://doi.org/10.3171/2014.10.jns132370","is_oa":true,"landing_page_url":"https://doi.org/10.3171/2014.10.jns132370","pdf_url":"https://thejns.org/downloadpdf/journals/j-neurosurg/123/1/article-p232.pdf","source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},{"id":"pmid:25479124","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25479124","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurosurgery","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3455645","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4457704","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4457704","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4457704","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Neurosurg","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3171/2014.10.jns132370","doi":"https://doi.org/10.3171/2014.10.jns132370","is_oa":true,"landing_page_url":"https://doi.org/10.3171/2014.10.jns132370","pdf_url":"https://thejns.org/downloadpdf/journals/j-neurosurg/123/1/article-p232.pdf","source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8999999761581421,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2151597309","display_name":"WINCS and DBS","funder_award_id":"R01NS070872","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G2331440055","display_name":"WincsNanotrode development for DBS","funder_award_id":"R01NS075013","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G2637722977","display_name":"Targeted intraspinal stimulation for restoration of limb movement following spina","funder_award_id":"R21NS087320","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3325024525","display_name":"Promoting Tumor Immunity by Cross-linking B7-DC","funder_award_id":"R01CA104996","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4700852728","display_name":null,"funder_award_id":"R01 NS","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6267815536","display_name":"The Mayo Clinic IMSD: Developing scientists through disease-relevant research","funder_award_id":"R25GM055252","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320310230","display_name":"Grainger Foundation","ror":"https://ror.org/0139q7h64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1998409337.pdf","grobid_xml":"https://content.openalex.org/works/W1998409337.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1475473394","https://openalex.org/W1481631390","https://openalex.org/W1542503752","https://openalex.org/W1543736831","https://openalex.org/W1587166006","https://openalex.org/W1889535261","https://openalex.org/W1980821091","https://openalex.org/W1984682622","https://openalex.org/W2000185603","https://openalex.org/W2016686264","https://openalex.org/W2020888800","https://openalex.org/W2053591157","https://openalex.org/W2055336281","https://openalex.org/W2056225116","https://openalex.org/W2057861997","https://openalex.org/W2065667887","https://openalex.org/W2066593625","https://openalex.org/W2083303145","https://openalex.org/W2098139066","https://openalex.org/W2098161293","https://openalex.org/W2099534949","https://openalex.org/W2115311231","https://openalex.org/W2132105820","https://openalex.org/W2138282647","https://openalex.org/W2138750758","https://openalex.org/W2140785628","https://openalex.org/W2142004558","https://openalex.org/W2146137168","https://openalex.org/W2147352907","https://openalex.org/W2152989183","https://openalex.org/W2282885433"],"related_works":["https://openalex.org/W2016205953","https://openalex.org/W4376226604","https://openalex.org/W2115311231","https://openalex.org/W2147997198","https://openalex.org/W2145055052","https://openalex.org/W7140178612","https://openalex.org/W3188301362","https://openalex.org/W2095685971","https://openalex.org/W1591061827","https://openalex.org/W6977560150"],"abstract_inverted_index":{"OBJECT:":[0],"Despite":[1],"a":[2,26,69,156,181,189,213,336],"promising":[3],"outlook,":[4],"existing":[5],"intraspinal":[6],"microstimulation":[7],"(ISMS)":[8],"techniques":[9,313],"for":[10,23,58,118,352],"restoring":[11,349],"functional":[12,302,331,350],"motor":[13,66],"control":[14,60,216,296],"after":[15],"spinal":[16,74,80,107,131,191,242,258,356],"cord":[17,75,81,108,132,243,259,357],"injury":[18],"are":[19],"not":[20],"yet":[21],"suitable":[22],"use":[24,41],"outside":[25],"controlled":[27,65,210,272],"laboratory":[28],"environment.":[29],"Thus,":[30],"successful":[31],"application":[32],"of":[33,42,49,56,61,72,84,105,173,201,240,252,270,276,284,293,309,330],"ISMS":[34,62,93,267,334],"therapy":[35],"in":[36,68,82,153,282],"humans":[37],"will":[38],"require":[39],"the":[40,106,110,136,142,165,199,230,241,249,253,257,285,294,310,340,345],"versatile":[43],"chronic":[44,355],"neurostimulation":[45,215],"systems.":[46],"The":[47,78,262],"objective":[48],"this":[50],"study":[51],"was":[52,90,124,178,209,268],"to":[53,63,95,158,169,197,247,323],"establish":[54],"proof":[55],"principle":[57],"wireless":[59,214,266],"evoke":[64,96,324],"function":[67],"rodent":[70],"model":[71],"complete":[73,102],"injury.":[76,358],"METHODS:":[77],"lumbar":[79],"each":[83],"17":[85],"fully":[86],"anesthetized":[87],"Sprague-Dawley":[88],"rats":[89,287,297],"stimulated":[91],"via":[92,129,225,333],"electrodes":[94,150,255],"hindlimb":[97],"function.":[98],"Nine":[99],"subjects":[100],"underwent":[101],"surgical":[103],"transection":[104],"at":[109],"T-4":[111],"level":[112],"7":[113],"days":[114],"before":[115],"stimulation.":[116],"Targeting":[117],"both":[119],"groups":[120],"(spinalized":[121],"and":[122,141,234,238,273,279,291],"control)":[123],"performed":[125,179],"under":[126],"visual":[127],"inspection":[128],"dorsal":[130,137,143],"landmarks":[133],"such":[134],"as":[135],"root":[138],"entry":[139],"zone":[140],"median":[144],"fissure.":[145],"Teflon-insulated":[146],"stimulating":[147,254],"platinum-iridium":[148],"microwire":[149],"(50":[151],"\u03bcm":[152],"diameter,":[154],"with":[155,354],"30-":[157],"60-\u03bcm":[159],"exposed":[160],"tip)":[161],"were":[162,223,245,314],"implanted":[163],"within":[164,256],"ventral":[166],"gray":[167],"matter":[168],"an":[170],"approximate":[171],"depth":[172],"1.8":[174],"mm.":[175],"Electrode":[176],"implantation":[177],"using":[180,212],"free-hand":[182],"delivery":[183],"technique":[184],"(n":[185,194,288,298],"=":[186,195,289,299],"12)":[187],"or":[188],"Kopf":[190],"frame":[192],"system":[193],"5)":[196],"compare":[198],"efficacy":[200],"these":[202],"2":[203,311],"commonly":[204],"used":[205],"targeting":[206,312,318],"techniques.":[207],"Stimulation":[208],"remotely":[211],"system.":[217],"Hindlimb":[218],"movements":[219,305],"evoked":[220,306],"by":[221,307],"stimulation":[222],"tracked":[224],"kinematic":[226],"markers":[227],"placed":[228],"on":[229],"hips,":[231],"knees,":[232],"ankles,":[233],"paws.":[235],"Postmortem":[236],"fixation":[237],"staining":[239],"tissue":[244],"conducted":[246],"determine":[248],"final":[250],"positions":[251],"tissue.":[260],"RESULTS:":[261],"results":[263],"show":[264],"that":[265],"capable":[269],"evoking":[271],"sustained":[274],"activation":[275],"ankle,":[277],"knee,":[278],"hip":[280],"muscles":[281],"90%":[283],"spinalized":[286],"9)":[290],"100%":[292],"healthy":[295],"8).":[300],"No":[301],"differences":[303],"between":[304],"either":[308],"revealed.":[315],"However,":[316,339],"frame-based":[317],"required":[319],"fewer":[320],"electrode":[321],"penetrations":[322],"target":[325],"movements.":[326],"CONCLUSIONS:":[327],"Clinical":[328],"restoration":[329],"movement":[332],"remains":[335],"distant":[337],"goal.":[338],"technology":[341],"presented":[342],"herein":[343],"represents":[344],"first":[346],"step":[347],"toward":[348],"independence":[351],"individuals":[353]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}