{"id":"https://openalex.org/W1998403631","doi":"https://doi.org/10.1016/j.schres.2012.11.006","title":"Lamotrigine augmentation in patients with schizophrenia who show partial response to clozapine treatment","display_name":"Lamotrigine augmentation in patients with schizophrenia who show partial response to clozapine treatment","publication_year":2012,"publication_date":"2012-12-02","ids":{"openalex":"https://openalex.org/W1998403631","doi":"https://doi.org/10.1016/j.schres.2012.11.006","mag":"1998403631","pmid":"https://pubmed.ncbi.nlm.nih.gov/23217729"},"language":"en","primary_location":{"id":"doi:10.1016/j.schres.2012.11.006","doi":"https://doi.org/10.1016/j.schres.2012.11.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.schres.2012.11.006","pdf_url":null,"source":{"id":"https://openalex.org/S144105592","display_name":"Schizophrenia Research","issn_l":"0920-9964","issn":["0920-9964","1573-2509"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophrenia Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055774699","display_name":"Sefa Vay\u0131so\u011flu","orcid":"https://orcid.org/0000-0002-9054-0777","observed_orcids":["https://orcid.org/0000-0002-9054-0777"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sefa Vay\u0131so\u011flu","raw_affiliation_strings":["Ak\u00e7akale State Hospital, Psychiatry Clinic, \u015eanl\u0131urfa, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ak\u00e7akale State Hospital, Psychiatry Clinic, \u015eanl\u0131urfa, Turkey","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041617662","display_name":"Ay\u015fe Elif Anil Ya\u011fcio\u011flu","orcid":"https://orcid.org/0000-0002-3269-150X","observed_orcids":["https://orcid.org/0000-0002-3269-150X"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"A. Elif An\u0131l Ya\u011fc\u0131o\u011flu","raw_affiliation_strings":["Hacettepe University, Faculty of Medicine, Department of Psychiatry, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hacettepe University, Faculty of Medicine, Department of Psychiatry, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111503860","display_name":"S\u00fcha Ya\u011fc\u0131o\u011flu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"S\u00fcha Ya\u011fc\u0131o\u011flu","raw_affiliation_strings":["Hacettepe University, Faculty of Medicine, Department of Biophysics, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hacettepe University, Faculty of Medicine, Department of Biophysics, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002231802","display_name":"Sevilay Karahan","orcid":"https://orcid.org/0000-0002-8692-7266","observed_orcids":["https://orcid.org/0000-0002-8692-7266"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Sevilay Karahan","raw_affiliation_strings":["Hacettepe University, Faculty of Medicine, Department of Biostatistics, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hacettepe University, Faculty of Medicine, Department of Biostatistics, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022884567","display_name":"O\u011fuzhan Karc\u0131","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799360972","display_name":"Hitit \u00dcniversitesi","ror":"https://ror.org/01x8m3269","country_code":"TR","type":"education","lineage":["https://openalex.org/I2799360972"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"O\u011fuzhan Karc\u0131","raw_affiliation_strings":["Hitit University, \u00c7orum Training and Research Hospital, Psychiatry Clinic, \u00c7orum, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hitit University, \u00c7orum Training and Research Hospital, Psychiatry Clinic, \u00c7orum, Turkey","institution_ids":["https://openalex.org/I2799360972"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024648215","display_name":"\u015eeref Can G\u00fcrel","orcid":"https://orcid.org/0000-0003-3261-6611","observed_orcids":["https://orcid.org/0000-0003-3261-6611"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u015e. Can G\u00fcrel","raw_affiliation_strings":["Birecik State Hospital, Psychiatry Clinic, \u015eanl\u0131urfa, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Birecik State Hospital, Psychiatry Clinic, \u015eanl\u0131urfa, Turkey","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039638534","display_name":"Mumin Kazim Yazici","orcid":"https://orcid.org/0000-0002-0963-2747","observed_orcids":["https://orcid.org/0000-0002-0963-2747"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"M. K\u00e2z\u0131m Yaz\u0131c\u0131","raw_affiliation_strings":["Hacettepe University, Faculty of Medicine, Department of Psychiatry, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hacettepe University, Faculty of Medicine, Department of Psychiatry, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5041617662"],"corresponding_institution_ids":["https://openalex.org/I66514158"],"apc_list":{"value":3910,"currency":"USD","value_usd":3910},"apc_paid":null,"fwci":2.3516,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.86278483,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"143","issue":"1","first_page":"207","last_page":"214"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12308","display_name":"Mental Health and Psychiatry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1211","display_name":"Philosophy"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lamotrigine","display_name":"lamotrigine","score":0.9909999966621399},{"id":"https://openalex.org/keywords/clozapine","display_name":"clozapine","score":0.9279999732971191}],"concepts":[{"id":"https://openalex.org/C2778802184","wikidata":"https://www.wikidata.org/wiki/Q410346","display_name":"Lamotrigine","level":3,"score":0.8667443990707397},{"id":"https://openalex.org/C2780864610","wikidata":"https://www.wikidata.org/wiki/Q221361","display_name":"Clozapine","level":3,"score":0.7303522229194641},{"id":"https://openalex.org/C2780135775","wikidata":"https://www.wikidata.org/wiki/Q7233251","display_name":"Positive and Negative Syndrome Scale","level":3,"score":0.709761917591095},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6141517758369446},{"id":"https://openalex.org/C21715850","wikidata":"https://www.wikidata.org/wiki/Q2720968","display_name":"Mismatch negativity","level":3,"score":0.5968015193939209},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5637685060501099},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.5494500994682312},{"id":"https://openalex.org/C2776000289","wikidata":"https://www.wikidata.org/wiki/Q5133761","display_name":"Clinical Global Impression","level":4,"score":0.48966363072395325},{"id":"https://openalex.org/C123273963","wikidata":"https://www.wikidata.org/wiki/Q624758","display_name":"Psychopathology","level":2,"score":0.42127466201782227},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37253063917160034},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3514127731323242},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3253708779811859},{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.24822905659675598},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.1036577820777893},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.08910810947418213},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000077213","descriptor_name":"Lamotrigine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003024","descriptor_name":"Clozapine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005072","descriptor_name":"Evoked Potentials, Auditory","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009483","descriptor_name":"Neuropsychological Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D014227","descriptor_name":"Triazines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.schres.2012.11.006","doi":"https://doi.org/10.1016/j.schres.2012.11.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.schres.2012.11.006","pdf_url":null,"source":{"id":"https://openalex.org/S144105592","display_name":"Schizophrenia Research","issn_l":"0920-9964","issn":["0920-9964","1573-2509"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophrenia Research","raw_type":"journal-article"},{"id":"pmid:23217729","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23217729","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophrenia research","raw_type":"Clinical Trial, Phase III"},{"id":"pmh:oai:earsiv.hitit.edu.tr:11491/1051","doi":null,"is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.schres.2012.11.006","pdf_url":null,"source":{"id":"https://openalex.org/S7407055343","display_name":"Hitit University Institutional Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W96351328","https://openalex.org/W595101455","https://openalex.org/W1506726456","https://openalex.org/W1793501383","https://openalex.org/W1970908493","https://openalex.org/W1976741101","https://openalex.org/W1991664166","https://openalex.org/W1996141026","https://openalex.org/W1997261150","https://openalex.org/W2001093965","https://openalex.org/W2003930934","https://openalex.org/W2006749341","https://openalex.org/W2007049511","https://openalex.org/W2009969771","https://openalex.org/W2014608077","https://openalex.org/W2016728154","https://openalex.org/W2019070525","https://openalex.org/W2021968198","https://openalex.org/W2022481935","https://openalex.org/W2030291506","https://openalex.org/W2032639611","https://openalex.org/W2037457244","https://openalex.org/W2041862233","https://openalex.org/W2054120497","https://openalex.org/W2054802990","https://openalex.org/W2056343700","https://openalex.org/W2063414327","https://openalex.org/W2072094368","https://openalex.org/W2082144190","https://openalex.org/W2082959963","https://openalex.org/W2085360366","https://openalex.org/W2086503579","https://openalex.org/W2086593869","https://openalex.org/W2089602570","https://openalex.org/W2091038866","https://openalex.org/W2093696735","https://openalex.org/W2101849101","https://openalex.org/W2109848582","https://openalex.org/W2115755283","https://openalex.org/W2123069664","https://openalex.org/W2125206183","https://openalex.org/W2125215108","https://openalex.org/W2140606211","https://openalex.org/W2143126574","https://openalex.org/W2156035025","https://openalex.org/W2159011576","https://openalex.org/W2165209294","https://openalex.org/W2502993979","https://openalex.org/W2599734864","https://openalex.org/W2808339913","https://openalex.org/W3090293687","https://openalex.org/W4211142904"],"related_works":["https://openalex.org/W2115755283","https://openalex.org/W2081824154","https://openalex.org/W2003930934","https://openalex.org/W2096415124","https://openalex.org/W2123069664","https://openalex.org/W7097767873","https://openalex.org/W2183765882","https://openalex.org/W2099750676","https://openalex.org/W2037457244","https://openalex.org/W2024293792"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}