{"id":"https://openalex.org/W1998378180","doi":"https://doi.org/10.1097/00000441-198904000-00001","title":"Cardiorenal effects of atrial natriuretic factor administration in congestive heart failure: Natriuresis and diuresis without hemodynamic alterations","display_name":"Cardiorenal effects of atrial natriuretic factor administration in congestive heart failure: Natriuresis and diuresis without hemodynamic alterations","publication_year":1989,"publication_date":"1989-04-01","ids":{"openalex":"https://openalex.org/W1998378180","doi":"https://doi.org/10.1097/00000441-198904000-00001","mag":"1998378180","pmid":"https://pubmed.ncbi.nlm.nih.gov/2565086"},"language":"en","primary_location":{"id":"doi:10.1097/00000441-198904000-00001","doi":"https://doi.org/10.1097/00000441-198904000-00001","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00000441-198904000-00001","pdf_url":null,"source":{"id":"https://openalex.org/S109361689","display_name":"The American Journal of the Medical Sciences","issn_l":"0002-9629","issn":["0002-9629","1538-2990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of the Medical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048931664","display_name":"Brian G. Firth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Brian G. Firth","raw_affiliation_strings":["Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235","University of Texas, Southwestern Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235","institution_ids":["https://openalex.org/I867280407"]},{"raw_affiliation_string":"University of Texas, Southwestern Medical Center","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037002410","display_name":"Rhonda Perna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1284037270","display_name":"Parkland Memorial Hospital","ror":"https://ror.org/0208r0146","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1284037270","https://openalex.org/I1286960001"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rhonda Perna","raw_affiliation_strings":["Cardiology and Renal Divisions, Department of Internal Medicine, University of Texas Southwestern Medical Center, Parkland Memorial Hospital, Dallas, Texas","University of Texas, Southwestern Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology and Renal Divisions, Department of Internal Medicine, University of Texas Southwestern Medical Center, Parkland Memorial Hospital, Dallas, Texas","institution_ids":["https://openalex.org/I1284037270","https://openalex.org/I867280407"]},{"raw_affiliation_string":"University of Texas, Southwestern Medical Center","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113555614","display_name":"J Bellomo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1284037270","display_name":"Parkland Memorial Hospital","ror":"https://ror.org/0208r0146","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1284037270","https://openalex.org/I1286960001"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph F. Bellomo","raw_affiliation_strings":["Cardiology and Renal Divisions, Department of Internal Medicine, University of Texas Southwestern Medical Center, Parkland Memorial Hospital, Dallas, Texas","University of Texas, Southwestern Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology and Renal Divisions, Department of Internal Medicine, University of Texas Southwestern Medical Center, Parkland Memorial Hospital, Dallas, Texas","institution_ids":["https://openalex.org/I1284037270","https://openalex.org/I867280407"]},{"raw_affiliation_string":"University of Texas, Southwestern Medical Center","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008309890","display_name":"Robert D. Toto","orcid":"https://orcid.org/0000-0001-9531-1749","observed_orcids":["https://orcid.org/0000-0001-9531-1749"]},"institutions":[{"id":"https://openalex.org/I1284037270","display_name":"Parkland Memorial Hospital","ror":"https://ror.org/0208r0146","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1284037270","https://openalex.org/I1286960001"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert D. Toto","raw_affiliation_strings":["Cardiology and Renal Divisions, Department of Internal Medicine, University of Texas Southwestern Medical Center, Parkland Memorial Hospital, Dallas, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology and Renal Divisions, Department of Internal Medicine, University of Texas Southwestern Medical Center, Parkland Memorial Hospital, Dallas, Texas","institution_ids":["https://openalex.org/I1284037270","https://openalex.org/I867280407"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5048931664"],"corresponding_institution_ids":["https://openalex.org/I867280407"],"apc_list":{"value":2940,"currency":"USD","value_usd":2940},"apc_paid":null,"fwci":0.7725,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.71901001,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"297","issue":"4","first_page":"203","last_page":"208"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11967","display_name":"Electrolyte and hormonal disorders","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14486","display_name":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atrial-natriuretic-peptide","display_name":"atrial natriuretic peptide","score":1.0},{"id":"https://openalex.org/keywords/congestive-heart-failure","display_name":"congestive heart failure","score":0.9909999966621399},{"id":"https://openalex.org/keywords/sodium-excretion","display_name":"sodium excretion","score":0.9729999899864197},{"id":"https://openalex.org/keywords/diuresis","display_name":"diuresis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/urinary-potassium-excretion","display_name":"potassium excretion","score":0.8840000033378601},{"id":"https://openalex.org/keywords/urine-flow-rate","display_name":"urinary flow rate","score":0.7860000133514404},{"id":"https://openalex.org/keywords/renal-plasma-flow","display_name":"renal plasma flow","score":0.925000011920929},{"id":"https://openalex.org/keywords/glomerular-filtration-rate","display_name":"glomerular filtration rate","score":1.0},{"id":"https://openalex.org/keywords/hemodynamic-effects","display_name":"hemodynamic effects","score":0.5799999833106995},{"id":"https://openalex.org/keywords/aldosterone","display_name":"aldosterone","score":0.746999979019165},{"id":"https://openalex.org/keywords/plasma-renin-activity","display_name":"plasma renin activity","score":0.9269999861717224}],"concepts":[{"id":"https://openalex.org/C174459258","wikidata":"https://www.wikidata.org/wiki/Q6980232","display_name":"Natriuresis","level":3,"score":0.8342175483703613},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7944684028625488},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.717365026473999},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6983602046966553},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.6823247075080872},{"id":"https://openalex.org/C142225936","wikidata":"https://www.wikidata.org/wiki/Q1129139","display_name":"Renal blood flow","level":3,"score":0.6410340070724487},{"id":"https://openalex.org/C2779547328","wikidata":"https://www.wikidata.org/wiki/Q584691","display_name":"Diuresis","level":3,"score":0.615844190120697},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.5809441804885864},{"id":"https://openalex.org/C138976137","wikidata":"https://www.wikidata.org/wiki/Q7201790","display_name":"Plasma renin activity","level":4,"score":0.5324170589447021},{"id":"https://openalex.org/C2778525890","wikidata":"https://www.wikidata.org/wiki/Q184564","display_name":"Aldosterone","level":2,"score":0.5296444892883301},{"id":"https://openalex.org/C21652263","wikidata":"https://www.wikidata.org/wiki/Q5347278","display_name":"Effective renal plasma flow","level":4,"score":0.4881744980812073},{"id":"https://openalex.org/C2779805383","wikidata":"https://www.wikidata.org/wiki/Q2500975","display_name":"Urine flow rate","level":3,"score":0.4796321988105774},{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.4696331024169922},{"id":"https://openalex.org/C2778069365","wikidata":"https://www.wikidata.org/wiki/Q78185357","display_name":"Atrial natriuretic peptide","level":2,"score":0.4589174687862396},{"id":"https://openalex.org/C119584498","wikidata":"https://www.wikidata.org/wiki/Q5449277","display_name":"Filtration fraction","level":4,"score":0.4330633878707886},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.41087356209754944},{"id":"https://openalex.org/C198710026","wikidata":"https://www.wikidata.org/wiki/Q898218","display_name":"Renin\u2013angiotensin system","level":3,"score":0.2755761742591858},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.22483718395233154}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004231","descriptor_name":"Diuresis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007275","descriptor_name":"Injections, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009318","descriptor_name":"Natriuresis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009320","descriptor_name":"Atrial Natriuretic Factor","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D018377","descriptor_name":"Neurotransmitter Agents","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00000441-198904000-00001","doi":"https://doi.org/10.1097/00000441-198904000-00001","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00000441-198904000-00001","pdf_url":null,"source":{"id":"https://openalex.org/S109361689","display_name":"The American Journal of the Medical Sciences","issn_l":"0002-9629","issn":["0002-9629","1538-2990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of the Medical Sciences","raw_type":"journal-article"},{"id":"pmid:2565086","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2565086","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of the medical sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.8100000023841858,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1964404358","https://openalex.org/W1966257496","https://openalex.org/W1975622210","https://openalex.org/W1977462706","https://openalex.org/W1978858292","https://openalex.org/W1985532348","https://openalex.org/W1985972379","https://openalex.org/W1993577260","https://openalex.org/W2012041356","https://openalex.org/W2016278714","https://openalex.org/W2023758236","https://openalex.org/W2034773285","https://openalex.org/W2040367941","https://openalex.org/W2041179424","https://openalex.org/W2042464106","https://openalex.org/W2045019226","https://openalex.org/W2052097767","https://openalex.org/W2054477494","https://openalex.org/W2056851052","https://openalex.org/W2065142882","https://openalex.org/W2076734878","https://openalex.org/W2084376098","https://openalex.org/W2093175759","https://openalex.org/W2099601233","https://openalex.org/W2111983335","https://openalex.org/W2129685902","https://openalex.org/W2146351587","https://openalex.org/W2157034872","https://openalex.org/W2253049708","https://openalex.org/W2295479440","https://openalex.org/W2322206236","https://openalex.org/W2410182003","https://openalex.org/W2410267155","https://openalex.org/W2411728052","https://openalex.org/W2412729899","https://openalex.org/W2436556188"],"related_works":["https://openalex.org/W2099601233","https://openalex.org/W2055906510","https://openalex.org/W2461349386","https://openalex.org/W1971609936","https://openalex.org/W1966482160","https://openalex.org/W1993910160","https://openalex.org/W2273911780","https://openalex.org/W1909275815","https://openalex.org/W2001875144","https://openalex.org/W2527825143"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}