{"id":"https://openalex.org/W1998353404","doi":"https://doi.org/10.1002/micr.20351","title":"Comparison of two rat models of cerebral ischemia under hyperglycemic conditions","display_name":"Comparison of two rat models of cerebral ischemia under hyperglycemic conditions","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W1998353404","doi":"https://doi.org/10.1002/micr.20351","mag":"1998353404","pmid":"https://pubmed.ncbi.nlm.nih.gov/17477421"},"language":"en","primary_location":{"id":"doi:10.1002/micr.20351","doi":"https://doi.org/10.1002/micr.20351","is_oa":false,"landing_page_url":"https://doi.org/10.1002/micr.20351","pdf_url":null,"source":{"id":"https://openalex.org/S51047553","display_name":"Microsurgery","issn_l":"0738-1085","issn":["0738-1085","1098-2752"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microsurgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070825468","display_name":"Longshan Liu","orcid":"https://orcid.org/0000-0001-5199-076X","observed_orcids":["https://orcid.org/0000-0001-5199-076X","https://orcid.org/0000-0003-2013-8827"]},"institutions":[{"id":"https://openalex.org/I4210107362","display_name":"H\u00f4pital Notre-Dame","ror":"https://ror.org/01w7qz648","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210107362","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4210142730","display_name":"Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0410a8y51","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Longshan Liu","raw_affiliation_strings":["Experimental Surgery Laboratory, CHUM Research Center, Notre-Dame Hospital, Montreal, QC, Canada","Drs. Longshan Liu and Ziying Wang contributed equally to the research and the preparation of the manuscript"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Surgery Laboratory, CHUM Research Center, Notre-Dame Hospital, Montreal, QC, Canada","institution_ids":["https://openalex.org/I4210107362","https://openalex.org/I4210142730"]},{"raw_affiliation_string":"Drs. Longshan Liu and Ziying Wang contributed equally to the research and the preparation of the manuscript","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100601367","display_name":"Ziying Wang","orcid":"https://orcid.org/0000-0003-3110-5318","observed_orcids":["https://orcid.org/0000-0003-3110-5318"]},"institutions":[{"id":"https://openalex.org/I4210107362","display_name":"H\u00f4pital Notre-Dame","ror":"https://ror.org/01w7qz648","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210107362","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4210142730","display_name":"Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0410a8y51","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ziying Wang","raw_affiliation_strings":["Drs. Longshan Liu and Ziying Wang contributed equally to the research and the preparation of the manuscript","Experimental Surgery Laboratory, CHUM Research Center, Notre-Dame Hospital, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drs. Longshan Liu and Ziying Wang contributed equally to the research and the preparation of the manuscript","institution_ids":[]},{"raw_affiliation_string":"Experimental Surgery Laboratory, CHUM Research Center, Notre-Dame Hospital, Montreal, QC, Canada","institution_ids":["https://openalex.org/I4210107362","https://openalex.org/I4210142730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100389014","display_name":"Xiang Wang","orcid":"https://orcid.org/0000-0002-2135-8576","observed_orcids":["https://orcid.org/0000-0002-2135-8576"]},"institutions":[{"id":"https://openalex.org/I4210107362","display_name":"H\u00f4pital Notre-Dame","ror":"https://ror.org/01w7qz648","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210107362","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4210142730","display_name":"Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0410a8y51","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Xiang Wang","raw_affiliation_strings":["Experimental Surgery Laboratory, CHUM Research Center, Notre-Dame Hospital, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Surgery Laboratory, CHUM Research Center, Notre-Dame Hospital, Montreal, QC, Canada","institution_ids":["https://openalex.org/I4210107362","https://openalex.org/I4210142730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060577282","display_name":"Lijun Song","orcid":"https://orcid.org/0000-0002-5114-6494","observed_orcids":["https://orcid.org/0000-0002-5114-6494"]},"institutions":[{"id":"https://openalex.org/I4210107362","display_name":"H\u00f4pital Notre-Dame","ror":"https://ror.org/01w7qz648","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210107362","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4210142730","display_name":"Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0410a8y51","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Lijun Song","raw_affiliation_strings":["Experimental Surgery Laboratory, CHUM Research Center, Notre-Dame Hospital, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Surgery Laboratory, CHUM Research Center, Notre-Dame Hospital, Montreal, QC, Canada","institution_ids":["https://openalex.org/I4210107362","https://openalex.org/I4210142730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100613611","display_name":"Huifang Chen","orcid":"https://orcid.org/0000-0002-4572-5879","observed_orcids":["https://orcid.org/0000-0002-4572-5879"]},"institutions":[{"id":"https://openalex.org/I4210107362","display_name":"H\u00f4pital Notre-Dame","ror":"https://ror.org/01w7qz648","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210107362","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4210142730","display_name":"Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0410a8y51","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Huifang Chen","raw_affiliation_strings":["Experimental Surgery Laboratory, CHUM Research Center, Notre-Dame Hospital, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Surgery Laboratory, CHUM Research Center, Notre-Dame Hospital, Montreal, QC, Canada","institution_ids":["https://openalex.org/I4210107362","https://openalex.org/I4210142730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080559656","display_name":"Chantal B\u00e9meur","orcid":"https://orcid.org/0000-0003-2757-5958","observed_orcids":["https://orcid.org/0000-0003-2757-5958"]},"institutions":[{"id":"https://openalex.org/I4210162151","display_name":"H\u00f4pital Saint-Luc","ror":"https://ror.org/04xk8j027","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4210162151","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Chantal B\u00e9meur","raw_affiliation_strings":["Neurological Sciences Research Units, St-Luc Hospital, Universite\u0301 de Montre\u0301al, Montreal, QC, Canada","Neurological Sciences Research Units, St-Luc Hospital, Universit\u00e9 de Montr\u00e9al, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurological Sciences Research Units, St-Luc Hospital, Universite\u0301 de Montre\u0301al, Montreal, QC, Canada","institution_ids":["https://openalex.org/I4210162151","https://openalex.org/I70931966"]},{"raw_affiliation_string":"Neurological Sciences Research Units, St-Luc Hospital, Universit\u00e9 de Montr\u00e9al, Montreal, QC, Canada","institution_ids":["https://openalex.org/I4210162151","https://openalex.org/I70931966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108383638","display_name":"Line Ste\u2010Marie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210107362","display_name":"H\u00f4pital Notre-Dame","ror":"https://ror.org/01w7qz648","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210107362","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Line Ste\u2010Marie","raw_affiliation_strings":["Interventional Neuroradiology Laboratory, Notre-Dame Hospital, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Interventional Neuroradiology Laboratory, Notre-Dame Hospital, Montreal, QC, Canada","institution_ids":["https://openalex.org/I4210107362"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055439760","display_name":"Jane A. Montgomery","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210162151","display_name":"H\u00f4pital Saint-Luc","ror":"https://ror.org/04xk8j027","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4210162151","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Jane Montgomery","raw_affiliation_strings":["Neurobiology Laboratory, St-Luc Hospital, Universite\u0301 de Montre\u0301al, Montreal, QC, Canada","Neurobiology Laboratory, St-Luc Hospital, Universit\u00e9 de Montr\u00e9al, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurobiology Laboratory, St-Luc Hospital, Universite\u0301 de Montre\u0301al, Montreal, QC, Canada","institution_ids":["https://openalex.org/I4210162151","https://openalex.org/I70931966"]},{"raw_affiliation_string":"Neurobiology Laboratory, St-Luc Hospital, Universit\u00e9 de Montr\u00e9al, Montreal, QC, Canada","institution_ids":["https://openalex.org/I4210162151","https://openalex.org/I70931966"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5055439760"],"corresponding_institution_ids":["https://openalex.org/I4210162151","https://openalex.org/I70931966"],"apc_list":{"value":3780,"currency":"USD","value_usd":3780},"apc_paid":null,"fwci":1.5466,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.81769773,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"27","issue":"4","first_page":"258","last_page":"262"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13796","display_name":"Neuroprotection in Cerebral Ischemia","score":0.014600000344216824,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperglycemia","display_name":"hyperglycemia","score":0.9020000100135803},{"id":"https://openalex.org/keywords/cerebral-ischemia","display_name":"cerebral ischemia","score":0.8529999852180481},{"id":"https://openalex.org/keywords/middle-cerebral-artery-occlusion","display_name":"middle cerebral artery occlusion","score":0.9390000104904175},{"id":"https://openalex.org/keywords/focal-cerebral-ischemia","display_name":"focal cerebral ischemia","score":0.7649999856948853},{"id":"https://openalex.org/keywords/ischemia-reperfusion","display_name":"ischemia-reperfusion","score":0.8059999942779541},{"id":"https://openalex.org/keywords/infarct-size","display_name":"infarct size","score":0.7519999742507935},{"id":"https://openalex.org/keywords/cerebral-cortex","display_name":"cerebral cortex","score":0.6399999856948853},{"id":"https://openalex.org/keywords/subcortical-infarction","display_name":"subcortical infarcts","score":0.8960000276565552},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8610000014305115},{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":0.8730000257492065},{"id":"https://openalex.org/keywords/antioxidant-therapy","display_name":"antioxidant therapy","score":0.8059999942779541},{"id":"https://openalex.org/keywords/animal-models-of-stroke","display_name":"animal models of stroke","score":0.6679999828338623},{"id":"https://openalex.org/keywords/rat-model","display_name":"rat model","score":0.4779999852180481}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9713804125785828},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.746208906173706},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.6107881665229797},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.572938859462738},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.5725288391113281},{"id":"https://openalex.org/C2777798775","wikidata":"https://www.wikidata.org/wiki/Q207550","display_name":"Infarction","level":3,"score":0.5303018093109131},{"id":"https://openalex.org/C2986274086","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Ascorbic acid","level":2,"score":0.5041099786758423},{"id":"https://openalex.org/C2779450755","wikidata":"https://www.wikidata.org/wiki/Q1209150","display_name":"Cerebral infarction","level":3,"score":0.5036696791648865},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4994025230407715},{"id":"https://openalex.org/C2781041448","wikidata":"https://www.wikidata.org/wiki/Q75839","display_name":"Cerebral cortex","level":2,"score":0.426618754863739},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3166542053222656},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2926756739616394},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.07145035266876221},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001205","descriptor_name":"Ascorbic Acid","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006943","descriptor_name":"Hyperglycemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006943","descriptor_name":"Hyperglycemia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020244","descriptor_name":"Infarction, Middle Cerebral Artery","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D020244","descriptor_name":"Infarction, Middle Cerebral Artery","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D020244","descriptor_name":"Infarction, Middle Cerebral Artery","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/micr.20351","doi":"https://doi.org/10.1002/micr.20351","is_oa":false,"landing_page_url":"https://doi.org/10.1002/micr.20351","pdf_url":null,"source":{"id":"https://openalex.org/S51047553","display_name":"Microsurgery","issn_l":"0738-1085","issn":["0738-1085","1098-2752"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microsurgery","raw_type":"journal-article"},{"id":"pmid:17477421","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17477421","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microsurgery","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1550602012","https://openalex.org/W1563482856","https://openalex.org/W1966628310","https://openalex.org/W1981951271","https://openalex.org/W2015640153","https://openalex.org/W2044437167","https://openalex.org/W2085622785","https://openalex.org/W2112505121","https://openalex.org/W2152091665","https://openalex.org/W2155885439","https://openalex.org/W2166653964"],"related_works":["https://openalex.org/W2039404300","https://openalex.org/W2372262514","https://openalex.org/W235164468","https://openalex.org/W2413902526","https://openalex.org/W1991237280","https://openalex.org/W2409509573","https://openalex.org/W1977216789","https://openalex.org/W2033251545","https://openalex.org/W2075368594","https://openalex.org/W228991539"],"abstract_inverted_index":{"Hyperglycemia":[0,104],"worsens":[1],"outcome":[2],"of":[3,97,123,132,155],"stroke":[4],"either":[5,131],"in":[6,11,56,67,79,138],"the":[7,15,57,64,68,76,80,85,98,106,120,133],"clinical":[8],"setting":[9],"or":[10],"animal":[12],"models.":[13],"In":[14,126],"present":[16],"study,":[17],"two":[18,134],"focal":[19],"cerebral":[20,25,65,107],"ischemia":[21,36],"models,":[22],"permanent":[23,69],"middle":[24],"artery":[26],"occlusion":[27],"(MCAO,":[28],"3-4":[29],"h)":[30],"and":[31,84,93,112],"reversible":[32,81],"MCAO":[33,70,82,135],"(1":[34],"h":[35,39],"+":[37],"3":[38],"reperfusion),":[40],"under":[41],"hyperglycemic":[42,124,147],"conditions":[43],"were":[44,88],"compared.":[45],"Using":[46],"2,3,5-triphenyltetrazolium":[47],"chloride":[48],"staining":[49],"to":[50,63,75,110],"define":[51],"viable":[52],"tissue,":[53],"this":[54],"resulted":[55,137],"infarction":[58,140],"area":[59,78],"being":[60],"confined":[61],"primarily":[62],"cortex":[66],"group,":[71,83],"while":[72],"it":[73],"extended":[74],"subcortical":[77],"lesion":[86],"areas":[87],"respectively":[89],"27.7":[90],"+/-":[91,95],"5.3%":[92],"46.8":[94],"12.0%":[96],"ipsilateral":[99],"hemisphere":[100],"(P":[101],"=":[102],"0.012).":[103],"accelerated":[105],"damage":[108],"compared":[109],"normoglycemia":[111],"ascorbic":[113],"acid":[114],"pre-treatment":[115],"maintained":[116],"tissue":[117],"viability":[118],"during":[119],"acute":[121],"phase":[122],"MCAO.":[125],"conclusion,":[127],"hyperglycemia":[128],"combined":[129],"with":[130,142],"models":[136,148],"rapid":[139],"associated":[141],"increased":[143],"oxidative":[144],"stress.":[145],"The":[146],"are":[149],"suitable":[150],"for":[151],"pharmaceutical":[152],"therapeutic":[153],"studies":[154],"antioxidant":[156],"efficacy.":[157]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}