{"id":"https://openalex.org/W1998287271","doi":"https://doi.org/10.1016/0304-4165(76)90043-x","title":"The subcellular distribution and partial characterization of cholinesterase activities of canine platelets","display_name":"The subcellular distribution and partial characterization of cholinesterase activities of canine platelets","publication_year":1976,"publication_date":"1976-04-01","ids":{"openalex":"https://openalex.org/W1998287271","doi":"https://doi.org/10.1016/0304-4165(76)90043-x","mag":"1998287271","pmid":"https://pubmed.ncbi.nlm.nih.gov/6047"},"language":"en","primary_location":{"id":"doi:10.1016/0304-4165(76)90043-x","doi":"https://doi.org/10.1016/0304-4165(76)90043-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0304-4165(76)90043-x","pdf_url":null,"source":{"id":"https://openalex.org/S4210238601","display_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","issn_l":"0304-4165","issn":["0304-4165","1872-8006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022794362","display_name":"Kenneth M. Lovette","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth M. Lovette","raw_affiliation_strings":["Departments of Biochemistry and Pathology, University of North Carolina, Chapel Hill, N.C., U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biochemistry and Pathology, University of North Carolina, Chapel Hill, N.C., U.S.A","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103464295","display_name":"Hanson Y.K. Chuang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hanson Y.K. Chuang","raw_affiliation_strings":["Departments of Biochemistry and Pathology, University of North Carolina, Chapel Hill, N.C., U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biochemistry and Pathology, University of North Carolina, Chapel Hill, N.C., U.S.A","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003308022","display_name":"S. Fazal Mohammad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Fazal Mohammad","raw_affiliation_strings":["Departments of Biochemistry and Pathology, University of North Carolina, Chapel Hill, N.C., U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biochemistry and Pathology, University of North Carolina, Chapel Hill, N.C., U.S.A","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111630904","display_name":"Reginald G. Mason","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Reginald G. Mason","raw_affiliation_strings":["Departments of Biochemistry and Pathology, University of North Carolina, Chapel Hill, N.C., U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biochemistry and Pathology, University of North Carolina, Chapel Hill, N.C., U.S.A","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5103464295"],"corresponding_institution_ids":["https://openalex.org/I114027177"],"apc_list":{"value":3310,"currency":"USD","value_usd":3310},"apc_paid":null,"fwci":0.333,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.55588473,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"428","issue":"2","first_page":"355","last_page":"368"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases","score":0.5210000276565552,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases","score":0.5210000276565552,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.34860000014305115,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cholinesterase","display_name":"cholinesterase","score":0.8970000147819519},{"id":"https://openalex.org/keywords/canine-platelets","display_name":"canine platelets","score":0.9010000228881836},{"id":"https://openalex.org/keywords/subcellular-localization","display_name":"subcellular localization","score":0.9750000238418579},{"id":"https://openalex.org/keywords/platelet-membrane","display_name":"platelet membrane","score":0.8949999809265137},{"id":"https://openalex.org/keywords/platelet-granules","display_name":"platelet granules","score":0.6309999823570251},{"id":"https://openalex.org/keywords/enzyme-kinetics","display_name":"enzyme kinetics","score":0.675000011920929},{"id":"https://openalex.org/keywords/cell-disruption","display_name":"cell disruption","score":0.42899999022483826},{"id":"https://openalex.org/keywords/density-gradient-fractionation","display_name":"density gradient fractionation","score":0.6320000290870667},{"id":"https://openalex.org/keywords/platelet-secretion","display_name":"platelet secretion","score":0.40400001406669617}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.792883038520813},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.7094753980636597},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.7075002193450928},{"id":"https://openalex.org/C57409179","wikidata":"https://www.wikidata.org/wiki/Q1218293","display_name":"Lysis","level":2,"score":0.6863439679145813},{"id":"https://openalex.org/C31896038","wikidata":"https://www.wikidata.org/wiki/Q415635","display_name":"Cholinesterase","level":2,"score":0.5789573788642883},{"id":"https://openalex.org/C49760210","wikidata":"https://www.wikidata.org/wiki/Q5596727","display_name":"Granule (geology)","level":2,"score":0.5215173363685608},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5166144967079163},{"id":"https://openalex.org/C2777292125","wikidata":"https://www.wikidata.org/wiki/Q409166","display_name":"Thrombin","level":3,"score":0.5033139586448669},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.489688903093338},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.4333626627922058},{"id":"https://openalex.org/C2778816929","wikidata":"https://www.wikidata.org/wiki/Q22676679","display_name":"Acetylcholinesterase","level":3,"score":0.41816800832748413},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3638420104980469},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.11454606056213379},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08492329716682434},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000118","descriptor_name":"Acetylglucosaminidase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D002800","descriptor_name":"Cholinesterase Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002802","descriptor_name":"Cholinesterases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002802","descriptor_name":"Cholinesterases","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007770","descriptor_name":"L-Lactate Dehydrogenase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013347","descriptor_name":"Subcellular Fractions","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D013917","descriptor_name":"Thrombin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0304-4165(76)90043-x","doi":"https://doi.org/10.1016/0304-4165(76)90043-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0304-4165(76)90043-x","pdf_url":null,"source":{"id":"https://openalex.org/S4210238601","display_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","issn_l":"0304-4165","issn":["0304-4165","1872-8006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","raw_type":"journal-article"},{"id":"pmid:6047","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6047","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W287398703","https://openalex.org/W1513285127","https://openalex.org/W1775749144","https://openalex.org/W1817187376","https://openalex.org/W1966401537","https://openalex.org/W1972162561","https://openalex.org/W2009489000","https://openalex.org/W2027075986","https://openalex.org/W2033005806","https://openalex.org/W2080967232","https://openalex.org/W2143964792"],"related_works":["https://openalex.org/W2014838476","https://openalex.org/W2009489000","https://openalex.org/W2010230985","https://openalex.org/W2469136268","https://openalex.org/W125599838","https://openalex.org/W2048886671","https://openalex.org/W2051291538","https://openalex.org/W2438412224","https://openalex.org/W2092552887","https://openalex.org/W1988878380"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}