{"id":"https://openalex.org/W1998281904","doi":"https://doi.org/10.1016/s0896-8411(05)80037-x","title":"Monoclonal anti-la antibody derived from a mouse with experimental SLE is similar to human anti-la antibodies","display_name":"Monoclonal anti-la antibody derived from a mouse with experimental SLE is similar to human anti-la antibodies","publication_year":1990,"publication_date":"1990-12-01","ids":{"openalex":"https://openalex.org/W1998281904","doi":"https://doi.org/10.1016/s0896-8411(05)80037-x","mag":"1998281904","pmid":"https://pubmed.ncbi.nlm.nih.gov/1708260"},"language":"en","primary_location":{"id":"doi:10.1016/s0896-8411(05)80037-x","doi":"https://doi.org/10.1016/s0896-8411(05)80037-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0896-8411(05)80037-x","pdf_url":null,"source":{"id":"https://openalex.org/S187826688","display_name":"Journal of Autoimmunity","issn_l":"0896-8411","issn":["0896-8411","1095-9157"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Autoimmunity","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057431624","display_name":"Daniel Offen","orcid":"https://orcid.org/0000-0002-1102-4521","observed_orcids":["https://orcid.org/0000-0002-1102-4521"]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Daniel Offen","raw_affiliation_strings":["Department of Organic Chemistry, Weizmann Institute of Science, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Organic Chemistry, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085884949","display_name":"Shlomo Mendlovic","orcid":"https://orcid.org/0000-0002-0587-1169","observed_orcids":["https://orcid.org/0000-0002-0587-1169"]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Shlomo Mendlovic","raw_affiliation_strings":["Department of Chemical Immunology, The Weizmann Institute of Science, Rehovot 76100, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Immunology, The Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008616655","display_name":"H FRICKE","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Harald Fricke","raw_affiliation_strings":["Department of Chemical Immunology, The Weizmann Institute of Science, Rehovot 76100, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Immunology, The Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045761416","display_name":"Ruth Sperling","orcid":"https://orcid.org/0000-0002-8950-4584","observed_orcids":["https://orcid.org/0000-0002-8950-4584"]},"institutions":[{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Ruth Sperling","raw_affiliation_strings":["Department of Genetics, The Hebrew University, Jerusalem, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, The Hebrew University, Jerusalem, Israel","institution_ids":["https://openalex.org/I197251160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047459030","display_name":"Joseph M. Sperling","orcid":"https://orcid.org/0000-0003-1916-5633","observed_orcids":["https://orcid.org/0000-0003-1916-5633"]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Joseph Sperling","raw_affiliation_strings":["Department of Organic Chemistry The Weizmann Institute of Science, Rehovot 76100, Israel","Dept. of Organic Chemistry, The Weizmann Institute of Science, Rehovot, 76100, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Organic Chemistry The Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Dept. of Organic Chemistry, The Weizmann Institute of Science, Rehovot, 76100, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020352199","display_name":"Edna Mozes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Edna Mozes","raw_affiliation_strings":["Department of Chemical Immunology, The Weizmann Institute of Science, Rehovot 76100, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Immunology, The Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I53964585"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5020352199"],"corresponding_institution_ids":["https://openalex.org/I53964585"],"apc_list":{"value":5420,"currency":"USD","value_usd":5420},"apc_paid":null,"fwci":1.0828,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.75805255,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":"3","issue":"6","first_page":"701","last_page":"713"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/la-antigen","display_name":"La antigen","score":0.9089999794960022},{"id":"https://openalex.org/keywords/anti-ssb-antibodies","display_name":"anti-SSB antibodies","score":0.7739999890327454},{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.9070000052452087},{"id":"https://openalex.org/keywords/monoclonal-antibodies","display_name":"monoclonal antibodies","score":0.8529999852180481},{"id":"https://openalex.org/keywords/anti-idiotypic-antibodies","display_name":"anti-idiotypic antibodies","score":0.6869999766349792},{"id":"https://openalex.org/keywords/epitope-mapping","display_name":"epitope mapping","score":0.7519999742507935},{"id":"https://openalex.org/keywords/nuclear-antigens","display_name":"nuclear antigens","score":0.6439999938011169},{"id":"https://openalex.org/keywords/speckled-pattern","display_name":"speckled pattern","score":0.7950000166893005},{"id":"https://openalex.org/keywords/small-rna","display_name":"small RNA","score":0.7789999842643738},{"id":"https://openalex.org/keywords/autoantibody-cross-reactivity","display_name":"autoantibody cross-reactivity","score":0.6940000057220459},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.4740000069141388}],"concepts":[{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.8759710788726807},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.756558895111084},{"id":"https://openalex.org/C74505204","wikidata":"https://www.wikidata.org/wiki/Q1047644","display_name":"Idiotype","level":4,"score":0.7561334371566772},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.7535505890846252},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6659424304962158},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6021814942359924},{"id":"https://openalex.org/C149443304","wikidata":"https://www.wikidata.org/wiki/Q185390","display_name":"Anti-nuclear antibody","level":4,"score":0.5805540680885315},{"id":"https://openalex.org/C2778236600","wikidata":"https://www.wikidata.org/wiki/Q592324","display_name":"Immunofluorescence","level":3,"score":0.5593520998954773},{"id":"https://openalex.org/C163864487","wikidata":"https://www.wikidata.org/wiki/Q6901461","display_name":"Monoclonal","level":4,"score":0.49327224493026733},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4686388671398163},{"id":"https://openalex.org/C2780130043","wikidata":"https://www.wikidata.org/wiki/Q192360","display_name":"Autoimmunity","level":3,"score":0.42910271883010864},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.41542357206344604},{"id":"https://openalex.org/C163764329","wikidata":"https://www.wikidata.org/wiki/Q785022","display_name":"Autoantibody","level":3,"score":0.37494874000549316},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3494427800178528}],"mesh":[{"descriptor_ui":"D000097585","descriptor_name":"SS-B Antigen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001324","descriptor_name":"Autoantigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001667","descriptor_name":"Binding, Competitive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008809","descriptor_name":"Mice, Inbred C3H","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011233","descriptor_name":"Precipitin Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012261","descriptor_name":"Ribonucleoproteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015151","descriptor_name":"Immunoblotting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0896-8411(05)80037-x","doi":"https://doi.org/10.1016/s0896-8411(05)80037-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0896-8411(05)80037-x","pdf_url":null,"source":{"id":"https://openalex.org/S187826688","display_name":"Journal of Autoimmunity","issn_l":"0896-8411","issn":["0896-8411","1095-9157"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Autoimmunity","raw_type":"journal-article"},{"id":"pmid:1708260","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1708260","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of autoimmunity","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320315026","display_name":"Weizmann UK","ror":"https://ror.org/04bjpr751"},{"id":"https://openalex.org/F4320320946","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W9131470","https://openalex.org/W160997634","https://openalex.org/W210302837","https://openalex.org/W284187410","https://openalex.org/W1496392745","https://openalex.org/W1496430412","https://openalex.org/W1502103265","https://openalex.org/W1554364726","https://openalex.org/W1607146370","https://openalex.org/W1910342421","https://openalex.org/W1976732266","https://openalex.org/W1984927734","https://openalex.org/W1993243592","https://openalex.org/W2010033210","https://openalex.org/W2011699726","https://openalex.org/W2018322200","https://openalex.org/W2021783076","https://openalex.org/W2022915892","https://openalex.org/W2047026229","https://openalex.org/W2058962713","https://openalex.org/W2059161182","https://openalex.org/W2070356374","https://openalex.org/W2072927794","https://openalex.org/W2085402165","https://openalex.org/W2089578769","https://openalex.org/W2100837269","https://openalex.org/W2101108802","https://openalex.org/W2103027823","https://openalex.org/W2113135200","https://openalex.org/W2128635872","https://openalex.org/W2146203649","https://openalex.org/W2165597690","https://openalex.org/W2426175606"],"related_works":["https://openalex.org/W1965068360","https://openalex.org/W2085402165","https://openalex.org/W7100302420","https://openalex.org/W103637832","https://openalex.org/W7096952758","https://openalex.org/W1541258859","https://openalex.org/W2104435943","https://openalex.org/W7097707210","https://openalex.org/W1983907809","https://openalex.org/W2032735845"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}