{"id":"https://openalex.org/W1998240074","doi":"https://doi.org/10.1034/j.1399-3046.2000.00082.x","title":"Use of anti\u2010hypertensive medications and post\u2010transplant renal allograft function in children","display_name":"Use of anti\u2010hypertensive medications and post\u2010transplant renal allograft function in children","publication_year":2000,"publication_date":"2000-02-01","ids":{"openalex":"https://openalex.org/W1998240074","doi":"https://doi.org/10.1034/j.1399-3046.2000.00082.x","mag":"1998240074","pmid":"https://pubmed.ncbi.nlm.nih.gov/10731054"},"language":"en","primary_location":{"id":"doi:10.1034/j.1399-3046.2000.00082.x","doi":"https://doi.org/10.1034/j.1399-3046.2000.00082.x","is_oa":false,"landing_page_url":"https://doi.org/10.1034/j.1399-3046.2000.00082.x","pdf_url":null,"source":{"id":"https://openalex.org/S27713550","display_name":"Pediatric Transplantation","issn_l":"1397-3142","issn":["1397-3142","1399-3046"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033463159","display_name":"Jonathan M. Sorof","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157394403","display_name":"Baylor University","ror":"https://ror.org/005781934","country_code":"US","type":"education","lineage":["https://openalex.org/I157394403"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan M. Sorof","raw_affiliation_strings":["Department of Pediatrics, Baylor University School of Medicine, Houston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Baylor University School of Medicine, Houston, Texas, USA","institution_ids":["https://openalex.org/I157394403","https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012594790","display_name":"Stuart L. Goldstein","orcid":"https://orcid.org/0000-0003-3711-8785","observed_orcids":["https://orcid.org/0000-0003-3711-8785"]},"institutions":[{"id":"https://openalex.org/I157394403","display_name":"Baylor University","ror":"https://ror.org/005781934","country_code":"US","type":"education","lineage":["https://openalex.org/I157394403"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stuart L. Goldstein","raw_affiliation_strings":["1Department of Pediatrics, Baylor University School of Medicine, and 2University of Texas, Houston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Pediatrics, Baylor University School of Medicine, and 2University of Texas, Houston, Texas, USA","institution_ids":["https://openalex.org/I157394403","https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020259997","display_name":"Eileen D. Brewer","orcid":"https://orcid.org/0000-0002-7365-5986","observed_orcids":["https://orcid.org/0000-0002-7365-5986"]},"institutions":[{"id":"https://openalex.org/I157394403","display_name":"Baylor University","ror":"https://ror.org/005781934","country_code":"US","type":"education","lineage":["https://openalex.org/I157394403"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eileen D. Brewer","raw_affiliation_strings":["1Department of Pediatrics, Baylor University School of Medicine, and 2University of Texas, Houston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Pediatrics, Baylor University School of Medicine, and 2University of Texas, Houston, Texas, USA","institution_ids":["https://openalex.org/I157394403","https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053439839","display_name":"Helen M. Steiger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157394403","display_name":"Baylor University","ror":"https://ror.org/005781934","country_code":"US","type":"education","lineage":["https://openalex.org/I157394403"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Helen M. Steiger","raw_affiliation_strings":["1Department of Pediatrics, Baylor University School of Medicine, and 2University of Texas, Houston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Pediatrics, Baylor University School of Medicine, and 2University of Texas, Houston, Texas, USA","institution_ids":["https://openalex.org/I157394403","https://openalex.org/I181547552"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023828011","display_name":"Ronald J. Portman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157394403","display_name":"Baylor University","ror":"https://ror.org/005781934","country_code":"US","type":"education","lineage":["https://openalex.org/I157394403"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald J. Portman","raw_affiliation_strings":["1Department of Pediatrics, Baylor University School of Medicine, and 2University of Texas, Houston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department of Pediatrics, Baylor University School of Medicine, and 2University of Texas, Houston, Texas, USA","institution_ids":["https://openalex.org/I157394403","https://openalex.org/I181547552"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3730,"currency":"USD","value_usd":3730},"apc_paid":null,"fwci":1.3561,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.7979798,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"4","issue":"1","first_page":"21","last_page":"27"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pediatric-kidney-transplantation","display_name":"pediatric kidney transplantation","score":0.6639999747276306},{"id":"https://openalex.org/keywords/post-transplant-hypertension","display_name":"post-transplant hypertension","score":0.9440000057220459},{"id":"https://openalex.org/keywords/antihypertensive-drugs","display_name":"antihypertensive drugs","score":0.9139999747276306},{"id":"https://openalex.org/keywords/renal-allograft-function","display_name":"renal allograft function","score":0.9139999747276306},{"id":"https://openalex.org/keywords/allograft-dysfunction","display_name":"allograft dysfunction","score":0.9629999995231628},{"id":"https://openalex.org/keywords/estimated-glomerular-filtration-rate","display_name":"estimated glomerular filtration rate","score":0.9359999895095825},{"id":"https://openalex.org/keywords/acute-rejection","display_name":"acute rejection","score":0.8539999723434448},{"id":"https://openalex.org/keywords/donor-type","display_name":"donor type","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9685564041137695},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.7255261540412903},{"id":"https://openalex.org/C2992666275","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Renal transplant","level":3,"score":0.685478150844574},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.5224989056587219},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5222678780555725},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.479907363653183},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3785470426082611},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3342530131340027},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3302111029624939}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002102","descriptor_name":"Cadaver","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005919","descriptor_name":"Glomerular Filtration Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006977","descriptor_name":"Hypertension, Renal","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006977","descriptor_name":"Hypertension, Renal","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016572","descriptor_name":"Cyclosporine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019520","descriptor_name":"Living Donors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1034/j.1399-3046.2000.00082.x","doi":"https://doi.org/10.1034/j.1399-3046.2000.00082.x","is_oa":false,"landing_page_url":"https://doi.org/10.1034/j.1399-3046.2000.00082.x","pdf_url":null,"source":{"id":"https://openalex.org/S27713550","display_name":"Pediatric Transplantation","issn_l":"1397-3142","issn":["1397-3142","1399-3046"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Transplantation","raw_type":"journal-article"},{"id":"pmid:10731054","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10731054","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric transplantation","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W50987173","https://openalex.org/W165043925","https://openalex.org/W1929190765","https://openalex.org/W1930046360","https://openalex.org/W1960255425","https://openalex.org/W1970174468","https://openalex.org/W1970744236","https://openalex.org/W1972398324","https://openalex.org/W1978019715","https://openalex.org/W1993430086","https://openalex.org/W1994697674","https://openalex.org/W1995430077","https://openalex.org/W1998310659","https://openalex.org/W2007940520","https://openalex.org/W2013123055","https://openalex.org/W2014482367","https://openalex.org/W2017687888","https://openalex.org/W2026728357","https://openalex.org/W2032539592","https://openalex.org/W2033699712","https://openalex.org/W2033833938","https://openalex.org/W2042192684","https://openalex.org/W2042598295","https://openalex.org/W2043481431","https://openalex.org/W2044497215","https://openalex.org/W2048779495","https://openalex.org/W2049565232","https://openalex.org/W2054827086","https://openalex.org/W2059579024","https://openalex.org/W2060800923","https://openalex.org/W2062040788","https://openalex.org/W2063655342","https://openalex.org/W2076195455","https://openalex.org/W2163961840","https://openalex.org/W2321629942","https://openalex.org/W2397884926","https://openalex.org/W2399770488","https://openalex.org/W2408437877","https://openalex.org/W2411361093","https://openalex.org/W2442350108","https://openalex.org/W2470247601","https://openalex.org/W3004788954","https://openalex.org/W4327494036"],"related_works":["https://openalex.org/W2163961840","https://openalex.org/W3013510761","https://openalex.org/W2904646484","https://openalex.org/W2131247472","https://openalex.org/W1930984523","https://openalex.org/W2032539592","https://openalex.org/W2323752081","https://openalex.org/W4285612757","https://openalex.org/W4319999520","https://openalex.org/W2116458201"],"abstract_inverted_index":{"Post-transplant":[0],"hypertension":[1,13,220],"is":[2,18,238],"a":[3,215],"common":[4],"occurrence":[5],"in":[6,206],"children.":[7],"The":[8],"relative":[9],"effect":[10],"of":[11,45,69,75,188],"this":[12,228],"on":[14],"renal":[15,26],"allograft":[16,53,242],"function":[17],"uncertain.":[19],"Examining":[20],"the":[21,43,90,233],"accumulated":[22],"data":[23,57,107],"for":[24,35,86,153,235],"pediatric":[25],"transplant":[27],"recipients":[28],"at":[29,133,140,148,172,201],"our":[30],"institution":[31],"from":[32,109,227],"monthly":[33,85,106],"visits":[34],"up":[36],"to":[37,116],"three":[38,102],"years,":[39],"we":[40,230],"determined":[41],"whether":[42],"use":[44],"anti-hypertensive":[46],"medications":[47,157,210,237],"(anti-HTN":[48],"medications)":[49],"was":[50,83,95,129,146,170],"associated":[51,239],"with":[52,159,240],"dysfunction.":[54],"Monthly":[55],"clinical":[56],"included":[58],"height,":[59],"weight,":[60],"serum":[61],"creatinine,":[62],"cyclosporin":[63],"A":[64,143],"(CsA)":[65],"trough":[66,197],"levels,":[67],"number":[68,74],"acute":[70,189],"rejection":[71,190],"episodes,":[72],"and":[73,104,136,192,221],"anti-HTN":[76,156,209,236],"medications.":[77],"Estimated":[78],"glomerular":[79],"filtration":[80],"rate":[81],"(eGFR)":[82],"calculated":[84],"each":[87],"patient":[88],"using":[89],"Schwartz":[91],"formula.":[92],"Time":[93],"post-transplant":[94,119,150,178,203,219],"grouped":[96,182],"into":[97],"6-month":[98],"intervals.":[99],"One":[100],"thousand":[101],"hundred":[103],"sixty-three":[105],"sets":[108],"6":[110,134],"months":[111,135],"(n":[112,120],"=":[113,121],"76":[114],"patients)":[115,123],"3":[117,141],"yr":[118],"47":[122],"were":[124,162,181,199],"analyzed.":[125],"Overall":[126],"mean":[127],"eGFR":[128,145,169],"75":[130],"mL/min/1.73":[131,138],"m2":[132,139],"54":[137],"yr.":[142],"lower":[144,168],"found":[147,171],"all":[149,176,202],"time":[151,204],"intervals":[152,205],"patients":[154,180,207],"receiving":[155,208],"compared":[158],"those":[160],"who":[161],"not":[163,175],"(p":[164,211],"<":[165,212],"0.01).":[166],"This":[167],"some":[173],"but":[174],"times":[177],"when":[179],"by":[183],"donor":[184],"type":[185],"or":[186],"history":[187],"episodes":[191],"analyzed":[193],"separately.":[194],"Mean":[195],"CsA":[196],"levels":[198],"higher":[200],"0.05).":[213],"While":[214],"causal":[216],"relationship":[217],"between":[218],"graft":[222],"dysfunction":[223],"cannot":[224],"be":[225],"established":[226],"study,":[229],"conclude":[231],"that":[232],"need":[234],"worse":[241],"function.":[243]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}