{"id":"https://openalex.org/W1998239684","doi":"https://doi.org/10.1016/j.foodchem.2013.07.067","title":"Active peptides from skate (Okamejei kenojei) skin gelatin diminish angiotensin-I converting enzyme activity and intracellular free radical-mediated oxidation","display_name":"Active peptides from skate (Okamejei kenojei) skin gelatin diminish angiotensin-I converting enzyme activity and intracellular free radical-mediated oxidation","publication_year":2013,"publication_date":"2013-07-24","ids":{"openalex":"https://openalex.org/W1998239684","doi":"https://doi.org/10.1016/j.foodchem.2013.07.067","mag":"1998239684","pmid":"https://pubmed.ncbi.nlm.nih.gov/24054237"},"language":"en","primary_location":{"id":"doi:10.1016/j.foodchem.2013.07.067","doi":"https://doi.org/10.1016/j.foodchem.2013.07.067","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.foodchem.2013.07.067","pdf_url":null,"source":{"id":"https://openalex.org/S98026630","display_name":"Food Chemistry","issn_l":"0308-8146","issn":["0308-8146","1873-7072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Chemistry","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1998239684"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103065067","display_name":"Dai\u2010Hung Ngo","orcid":"https://orcid.org/0000-0002-4025-1694","observed_orcids":["https://orcid.org/0000-0002-4025-1694"]},"institutions":[{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Dai-Hung Ngo","raw_affiliation_strings":["Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Republic of Korea","institution_ids":["https://openalex.org/I8991828"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030829661","display_name":"BoMi Ryu","orcid":"https://orcid.org/0000-0001-5797-500X","observed_orcids":["https://orcid.org/0000-0001-5797-500X"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"BoMi Ryu","raw_affiliation_strings":["School of Pharmacy, The University of Queensland, Brisbane, Qld 4072, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, The University of Queensland, Brisbane, Qld 4072, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037284987","display_name":"Se\u2010Kwon Kim","orcid":"https://orcid.org/0000-0001-6507-9539","observed_orcids":["https://orcid.org/0000-0001-6507-9539"]},"institutions":[{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Se-Kwon Kim","raw_affiliation_strings":["Department of Chemistry, Pukyong National University, Busan 608-737, Republic of Korea","Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Pukyong National University, Busan 608-737, Republic of Korea","institution_ids":["https://openalex.org/I8991828"]},{"raw_affiliation_string":"Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Republic of Korea","institution_ids":["https://openalex.org/I8991828"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5037284987"],"corresponding_institution_ids":["https://openalex.org/I8991828"],"apc_list":{"value":4930,"currency":"USD","value_usd":4930},"apc_paid":null,"fwci":10.0292,"has_fulltext":false,"cited_by_count":124,"citation_normalized_percentile":{"value":0.98564965,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"143","issue":null,"first_page":"246","last_page":"255"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14127","display_name":"Food Nutrient Composition and Product Development","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bioactive-peptides","display_name":"bioactive peptides","score":0.8410000205039978},{"id":"https://openalex.org/keywords/angiotensin-converting-enzyme-inhibition","display_name":"angiotensin-converting enzyme inhibition","score":0.9480000138282776},{"id":"https://openalex.org/keywords/antihypertensive-peptides","display_name":"antihypertensive peptides","score":0.8569999933242798},{"id":"https://openalex.org/keywords/antioxidant-peptides","display_name":"antioxidant peptides","score":0.6890000104904175},{"id":"https://openalex.org/keywords/free-radical-scavenging-activity","display_name":"free radical scavenging","score":0.9739999771118164},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.5550000071525574},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.7390000224113464},{"id":"https://openalex.org/keywords/antioxidant-enzymes","display_name":"antioxidant enzymes","score":0.7139999866485596},{"id":"https://openalex.org/keywords/enzymatic-hydrolysis","display_name":"enzymatic hydrolysis","score":0.8169999718666077},{"id":"https://openalex.org/keywords/functional-food-ingredients","display_name":"functional food ingredients","score":0.6830000281333923},{"id":"https://openalex.org/keywords/fish-by-products","display_name":"fish by-products","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8801699876785278},{"id":"https://openalex.org/C28800991","wikidata":"https://www.wikidata.org/wiki/Q15634405","display_name":"Hydrolysate","level":3,"score":0.8657103776931763},{"id":"https://openalex.org/C2779853653","wikidata":"https://www.wikidata.org/wiki/Q837104","display_name":"Skate","level":2,"score":0.6864114999771118},{"id":"https://openalex.org/C2778823387","wikidata":"https://www.wikidata.org/wiki/Q179254","display_name":"Gelatin","level":2,"score":0.6822887063026428},{"id":"https://openalex.org/C50817676","wikidata":"https://www.wikidata.org/wiki/Q7880534","display_name":"Ultrafiltration (renal)","level":2,"score":0.6589963436126709},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.6136825084686279},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.6023204326629639},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5501197576522827},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.5400018095970154},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.47763147950172424},{"id":"https://openalex.org/C2776714187","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Protease","level":3,"score":0.47176840901374817},{"id":"https://openalex.org/C2777752497","wikidata":"https://www.wikidata.org/wiki/Q286779","display_name":"IC50","level":3,"score":0.45333346724510193},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3709369897842407},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.15257248282432556},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.05483636260032654},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000806","descriptor_name":"Angiotensin-Converting Enzyme Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000806","descriptor_name":"Angiotensin-Converting Enzyme Inhibitors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005780","descriptor_name":"Gelatin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006868","descriptor_name":"Hydrolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007703","descriptor_name":"Peptidyl-Dipeptidase A","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010449","descriptor_name":"Peptide Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011492","descriptor_name":"Protein Hydrolysates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011492","descriptor_name":"Protein Hydrolysates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012860","descriptor_name":"Skates, Fish","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013381","descriptor_name":"Subtilisins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016166","descriptor_name":"Free Radical Scavengers","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D016166","descriptor_name":"Free Radical Scavengers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D029941","descriptor_name":"Fish Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D061307","descriptor_name":"Human Umbilical Vein Endothelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D061307","descriptor_name":"Human Umbilical Vein Endothelial Cells","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D061307","descriptor_name":"Human Umbilical Vein Endothelial Cells","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.foodchem.2013.07.067","doi":"https://doi.org/10.1016/j.foodchem.2013.07.067","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.foodchem.2013.07.067","pdf_url":null,"source":{"id":"https://openalex.org/S98026630","display_name":"Food Chemistry","issn_l":"0308-8146","issn":["0308-8146","1873-7072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Chemistry","raw_type":"journal-article"},{"id":"pmid:24054237","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24054237","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W1545016281","https://openalex.org/W1967782318","https://openalex.org/W1971246867","https://openalex.org/W1971975537","https://openalex.org/W1973574551","https://openalex.org/W1974561818","https://openalex.org/W1974999975","https://openalex.org/W1975004227","https://openalex.org/W1975796698","https://openalex.org/W1976179916","https://openalex.org/W1979416106","https://openalex.org/W1982832249","https://openalex.org/W1985328551","https://openalex.org/W1987000855","https://openalex.org/W1989542847","https://openalex.org/W1991776232","https://openalex.org/W1993224429","https://openalex.org/W1993303404","https://openalex.org/W1994075750","https://openalex.org/W1998182513","https://openalex.org/W2002840594","https://openalex.org/W2003694301","https://openalex.org/W2007459036","https://openalex.org/W2010937249","https://openalex.org/W2012275144","https://openalex.org/W2013951601","https://openalex.org/W2014616121","https://openalex.org/W2018194228","https://openalex.org/W2018669372","https://openalex.org/W2020395259","https://openalex.org/W2020868868","https://openalex.org/W2021209564","https://openalex.org/W2021261187","https://openalex.org/W2021660616","https://openalex.org/W2024537305","https://openalex.org/W2025521338","https://openalex.org/W2041162677","https://openalex.org/W2043446937","https://openalex.org/W2045978624","https://openalex.org/W2052031768","https://openalex.org/W2052870835","https://openalex.org/W2054751638","https://openalex.org/W2055754348","https://openalex.org/W2056092379","https://openalex.org/W2057525158","https://openalex.org/W2057908978","https://openalex.org/W2059172961","https://openalex.org/W2073110854","https://openalex.org/W2075270505","https://openalex.org/W2081962247","https://openalex.org/W2087447071","https://openalex.org/W2092234961","https://openalex.org/W2093974041","https://openalex.org/W2096431838","https://openalex.org/W2099476122","https://openalex.org/W2114311509","https://openalex.org/W2115896899","https://openalex.org/W2116717490","https://openalex.org/W2117456535","https://openalex.org/W2182772262","https://openalex.org/W2280640365","https://openalex.org/W2284344255"],"related_works":["https://openalex.org/W2051836390","https://openalex.org/W2009689206","https://openalex.org/W2057908978","https://openalex.org/W1969538331","https://openalex.org/W2503172822","https://openalex.org/W2010279842","https://openalex.org/W4409334930","https://openalex.org/W2013810121","https://openalex.org/W2045544524","https://openalex.org/W2171689175"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":8}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}