{"id":"https://openalex.org/W1998207224","doi":"https://doi.org/10.1021/bc9001163","title":"Multimodal Nanoagents for the Detection of Intravascular Thrombi","display_name":"Multimodal Nanoagents for the Detection of Intravascular Thrombi","publication_year":2009,"publication_date":"2009-05-20","ids":{"openalex":"https://openalex.org/W1998207224","doi":"https://doi.org/10.1021/bc9001163","mag":"1998207224","pmid":"https://pubmed.ncbi.nlm.nih.gov/19456115","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2733224"},"language":"en","primary_location":{"id":"doi:10.1021/bc9001163","doi":"https://doi.org/10.1021/bc9001163","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bc9001163","pdf_url":null,"source":{"id":"https://openalex.org/S155115410","display_name":"Bioconjugate Chemistry","issn_l":"1043-1802","issn":["1043-1802","1520-4812"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioconjugate Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2733224","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005270186","display_name":"Jason R. McCarthy","orcid":"https://orcid.org/0000-0002-5302-2030","observed_orcids":["https://orcid.org/0000-0002-5302-2030"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jason R. McCarthy","raw_affiliation_strings":["Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111482807","display_name":"Purvish Patel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Purvish Patel","raw_affiliation_strings":["Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033639587","display_name":"Ion Botnaru","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ion Botnaru","raw_affiliation_strings":["Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084789801","display_name":"Pouneh Haghayeghi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pouneh Haghayeghi","raw_affiliation_strings":["Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067255019","display_name":"Ralph Weissleder","orcid":"https://orcid.org/0000-0003-0828-4143","observed_orcids":["https://orcid.org/0000-0003-0828-4143"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ralph Weissleder","raw_affiliation_strings":["Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035255903","display_name":"Farouc Amin Jaffer","orcid":"https://orcid.org/0000-0001-7980-384X","observed_orcids":["https://orcid.org/0000-0001-7980-384X"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Farouc A. Jaffer","raw_affiliation_strings":["Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Imaging Research, Harvard Medical School and Massachusetts General Hospital, 149 13th Street, Room 5406, Charlestown, Massachusetts 02129, and Cardiovascular Research Center, Cardiology Division, Harvard Medical School and Massachusetts General Hospital, 185 Cambridge St Room 3206, Boston Massachusetts 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5005270186","https://openalex.org/A5035255903"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":4.2445,"has_fulltext":false,"cited_by_count":84,"citation_normalized_percentile":{"value":0.94379845,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"20","issue":"6","first_page":"1251","last_page":"1255"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.25440001487731934,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.25440001487731934,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.14980000257492065,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.10660000145435333,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intravascular-thrombi","display_name":"intravascular thrombi","score":0.859000027179718},{"id":"https://openalex.org/keywords/thrombosis-imaging","display_name":"thrombosis imaging","score":0.8659999966621399},{"id":"https://openalex.org/keywords/fluorescent-magnetic-nanoparticles","display_name":"fluorescent magnetic nanoparticles","score":0.7990000247955322},{"id":"https://openalex.org/keywords/fluorescence-imaging","display_name":"fluorescence imaging","score":0.8370000123977661},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"magnetic resonance imaging","score":0.972000002861023},{"id":"https://openalex.org/keywords/fibrinolysis","display_name":"fibrinolysis","score":0.8109999895095825},{"id":"https://openalex.org/keywords/thrombus-formation","display_name":"thrombus formation","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8673033714294434},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6807422637939453},{"id":"https://openalex.org/C2776825266","wikidata":"https://www.wikidata.org/wiki/Q1410794","display_name":"Fibrinolysis","level":2,"score":0.5629265308380127},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.5380527377128601},{"id":"https://openalex.org/C54173615","wikidata":"https://www.wikidata.org/wiki/Q27205","display_name":"Fibrin","level":2,"score":0.5353356599807739},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.5319509506225586},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4167739450931549},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.14078202843666077},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12977564334869385},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.11097389459609985},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0638471245765686},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001777","descriptor_name":"Blood Coagulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001808","descriptor_name":"Blood Vessels","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005337","descriptor_name":"Fibrin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005453","descriptor_name":"Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013927","descriptor_name":"Thrombosis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013927","descriptor_name":"Thrombosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D013927","descriptor_name":"Thrombosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013927","descriptor_name":"Thrombosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D026122","descriptor_name":"Factor XIIIa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1021/bc9001163","doi":"https://doi.org/10.1021/bc9001163","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bc9001163","pdf_url":null,"source":{"id":"https://openalex.org/S155115410","display_name":"Bioconjugate Chemistry","issn_l":"1043-1802","issn":["1043-1802","1520-4812"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioconjugate Chemistry","raw_type":"journal-article"},{"id":"pmid:19456115","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19456115","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioconjugate chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2733224","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2733224","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Bioconjug Chem","raw_type":"Text"},{"id":"pmh:oai:dash.harvard.edu:1/41384211","doi":null,"is_oa":true,"landing_page_url":"http://nrs.harvard.edu/urn-3:HUL.InstRepos:41384211","pdf_url":null,"source":{"id":"https://openalex.org/S4306401540","display_name":"Digital Access to Scholarship at Harvard (DASH) (Harvard University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I136199984","host_organization_name":"Harvard University","host_organization_lineage":["https://openalex.org/I136199984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2733224","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2733224","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Bioconjug Chem","raw_type":"Text"},"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1406893269","display_name":"Translational Program of Excellence in Nanotechnology","funder_award_id":"U01HL080731","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2457503501","display_name":"Small Animal Imaging Resource","funder_award_id":"U24CA092782","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7425843285","display_name":null,"funder_award_id":"UU54-CA126515","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7441681070","display_name":"The MIT-Harvard Center of Cancer Nanotechnology Excelle*","funder_award_id":"5u54ca119349-05","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8447957866","display_name":"Tumor-Stroma Interacions in the Tumor Microenvironment","funder_award_id":"U54CA126515","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G947370982","display_name":null,"funder_award_id":"U54 CA-119349","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W78645399","https://openalex.org/W1973776877","https://openalex.org/W1983549854","https://openalex.org/W1995054061","https://openalex.org/W2007341156","https://openalex.org/W2010081112","https://openalex.org/W2010752752","https://openalex.org/W2012016203","https://openalex.org/W2012079485","https://openalex.org/W2023122926","https://openalex.org/W2023951029","https://openalex.org/W2039026859","https://openalex.org/W2064859115","https://openalex.org/W2085861396","https://openalex.org/W2112334970","https://openalex.org/W2126226332","https://openalex.org/W2151790333","https://openalex.org/W2168252560","https://openalex.org/W2388746528"],"related_works":["https://openalex.org/W2080277744","https://openalex.org/W1989663127","https://openalex.org/W2417735474","https://openalex.org/W2309461639","https://openalex.org/W2769410216","https://openalex.org/W1972910517","https://openalex.org/W2064633228","https://openalex.org/W1971919437","https://openalex.org/W1967794926","https://openalex.org/W2971563883"],"abstract_inverted_index":{"Thrombosis":[0],"underlies":[1],"numerous":[2],"life-threatening":[3],"cardiovascular":[4],"syndromes.":[5,31],"Development":[6],"of":[7,29,46,61,67],"thrombosis-specific":[8],"molecular":[9],"imaging":[10],"agents":[11,55],"to":[12,42,64],"detect":[13],"and":[14,17,27,50,77,88,92],"monitor":[15],"thrombogenesis":[16],"fibrinolysis":[18],"in":[19,75,78],"vivo":[20,79],"could":[21],"improve":[22],"the":[23,59,65],"diagnosis,":[24],"risk":[25],"stratification,":[26],"treatment":[28],"thrombosis":[30],"To":[32],"this":[33],"end,":[34],"we":[35],"have":[36],"synthesized":[37],"efficient":[38],"multimodal":[39],"nanoagents":[40,82],"targeted":[41,57],"two":[43],"different":[44],"constituents":[45],"thrombi,":[47,87],"namely,":[48],"fibrin":[49],"activated":[51],"factor":[52],"XIII.":[53],"These":[54],"are":[56],"via":[58],"conjugation":[60],"peptide-targeting":[62],"ligands":[63],"surface":[66],"fluorescently":[68],"labeled":[69],"magnetic":[70,93],"nanoparticles.":[71],"As":[72],"demonstrated":[73],"by":[74],"vitro":[76],"studies,":[80],"both":[81],"possess":[83],"high":[84],"affinities":[85],"for":[86],"enable":[89],"mutimodal":[90],"fluorescence":[91],"resonance":[94],"imaging.":[95]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":9}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}