{"id":"https://openalex.org/W1998153574","doi":"https://doi.org/10.1016/s0736-0266(01)00172-3","title":"Tenascin\u2010C expression and distribution in cultured human chondrocytes and chondrosarcoma cells","display_name":"Tenascin\u2010C expression and distribution in cultured human chondrocytes and chondrosarcoma cells","publication_year":2002,"publication_date":"2002-07-01","ids":{"openalex":"https://openalex.org/W1998153574","doi":"https://doi.org/10.1016/s0736-0266(01)00172-3","mag":"1998153574","pmid":"https://pubmed.ncbi.nlm.nih.gov/12168675"},"language":"en","primary_location":{"id":"doi:10.1016/s0736-0266(01)00172-3","doi":"https://doi.org/10.1016/s0736-0266(01)00172-3","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0736-0266(01)00172-3","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/S0736-0266%2801%2900172-3","source":{"id":"https://openalex.org/S12558119","display_name":"Journal of Orthopaedic Research\u00ae","issn_l":"0736-0266","issn":["0736-0266","1554-527X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/S0736-0266%2801%2900172-3","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032254130","display_name":"Michelle A. Ghert","orcid":"https://orcid.org/0000-0002-4778-4522","observed_orcids":["https://orcid.org/0000-0002-4778-4522"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michelle A. Ghert","raw_affiliation_strings":["Division of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108425579","display_name":"Wen\u2010Ning Qi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wen\u2010Ning Qi","raw_affiliation_strings":["Division of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043777416","display_name":"Harold Erickson","orcid":"https://orcid.org/0000-0002-9104-8987","observed_orcids":["https://orcid.org/0000-0002-9104-8987"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harold P. Erickson","raw_affiliation_strings":["Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089546365","display_name":"Joel A. Block","orcid":"https://orcid.org/0000-0002-0330-7353","observed_orcids":["https://orcid.org/0000-0002-0330-7353"]},"institutions":[{"id":"https://openalex.org/I1285301757","display_name":"Rush University Medical Center","ror":"https://ror.org/01j7c0b24","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285301757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joel A. Block","raw_affiliation_strings":["Department of Cell Biology, Rush-Presbyterian St. Luke's Medical Center, Chicago, IL 60612, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, Rush-Presbyterian St. Luke's Medical Center, Chicago, IL 60612, USA","institution_ids":["https://openalex.org/I1285301757"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110238568","display_name":"Sean P. Scully","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sean P. Scully","raw_affiliation_strings":["Department of Orthopaedic Surgery, Mayo Clinic, 200 First Street SW, West 14A, Rochester, MN 55905, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Mayo Clinic, 200 First Street SW, West 14A, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5110238568"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":3970,"currency":"USD","value_usd":3970},"apc_paid":null,"fwci":0.5733,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.67040515,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"20","issue":"4","first_page":"834","last_page":"841"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.5336999893188477,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.5336999893188477,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.42750000953674316,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","score":0.03220000118017197,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tenascin-c","display_name":"tenascin-C","score":0.9010000228881836},{"id":"https://openalex.org/keywords/chondrocytes","display_name":"chondrocytes","score":0.734000027179718},{"id":"https://openalex.org/keywords/chondrosarcoma","display_name":"chondrosarcoma","score":0.9950000047683716},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.7179999947547913},{"id":"https://openalex.org/keywords/protein-isoforms","display_name":"protein isoforms","score":0.6959999799728394},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.8859999775886536},{"id":"https://openalex.org/keywords/articular-cartilage","display_name":"articular cartilage","score":0.9819999933242798},{"id":"https://openalex.org/keywords/tumor-extracellular-matrix","display_name":"tumor extracellular matrix","score":0.4620000123977661},{"id":"https://openalex.org/keywords/glycoprotein-expression","display_name":"glycoprotein expression","score":0.6769999861717224}],"concepts":[{"id":"https://openalex.org/C53345823","wikidata":"https://www.wikidata.org/wiki/Q5531554","display_name":"Gene isoform","level":3,"score":0.8084248900413513},{"id":"https://openalex.org/C117961784","wikidata":"https://www.wikidata.org/wiki/Q18027461","display_name":"Tenascin C","level":3,"score":0.8076716661453247},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.7046265602111816},{"id":"https://openalex.org/C2776302905","wikidata":"https://www.wikidata.org/wiki/Q1076087","display_name":"Chondrosarcoma","level":2,"score":0.6959922313690186},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.6342283487319946},{"id":"https://openalex.org/C2777738151","wikidata":"https://www.wikidata.org/wiki/Q1903925","display_name":"Tenascin","level":4,"score":0.5747064352035522},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5151315927505493},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5074097514152527},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.4965832829475403},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.4237402379512787},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.4228225350379944},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3753405809402466},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.34119418263435364},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3114127516746521},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15773114562034607},{"id":"https://openalex.org/C86492073","wikidata":"https://www.wikidata.org/wiki/Q413766","display_name":"Fibronectin","level":3,"score":0.1503579318523407},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.15008282661437988},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1478748917579651},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.14404591917991638},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10235077142715454}],"mesh":[{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002813","descriptor_name":"Chondrosarcoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002813","descriptor_name":"Chondrosarcoma","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019063","descriptor_name":"Tenascin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D019063","descriptor_name":"Tenascin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019902","descriptor_name":"Chondrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019902","descriptor_name":"Chondrocytes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0736-0266(01)00172-3","doi":"https://doi.org/10.1016/s0736-0266(01)00172-3","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0736-0266(01)00172-3","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/S0736-0266%2801%2900172-3","source":{"id":"https://openalex.org/S12558119","display_name":"Journal of Orthopaedic Research\u00ae","issn_l":"0736-0266","issn":["0736-0266","1554-527X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Research","raw_type":"journal-article"},{"id":"pmid:12168675","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12168675","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of orthopaedic research : official publication of the Orthopaedic Research Society","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0736-0266(01)00172-3","doi":"https://doi.org/10.1016/s0736-0266(01)00172-3","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0736-0266(01)00172-3","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/S0736-0266%2801%2900172-3","source":{"id":"https://openalex.org/S12558119","display_name":"Journal of Orthopaedic Research\u00ae","issn_l":"0736-0266","issn":["0736-0266","1554-527X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Orthopaedic Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G287124706","display_name":null,"funder_award_id":"AR42863","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G3179476580","display_name":"CHONDROCYTE REGULATION BY EXTRACELLULAR COLLAGEN","funder_award_id":"R29AR042863","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320306775","display_name":"Musculoskeletal Transplant Foundation","ror":"https://ror.org/011398447"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1998153574.pdf","grobid_xml":"https://content.openalex.org/works/W1998153574.grobid-xml"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W60692637","https://openalex.org/W1485340008","https://openalex.org/W1508590375","https://openalex.org/W1593205980","https://openalex.org/W1872026168","https://openalex.org/W1965333299","https://openalex.org/W1980779026","https://openalex.org/W1982622792","https://openalex.org/W1983894074","https://openalex.org/W1988180998","https://openalex.org/W1990941508","https://openalex.org/W1993885626","https://openalex.org/W1995713262","https://openalex.org/W1996599102","https://openalex.org/W1997867057","https://openalex.org/W2000246632","https://openalex.org/W2002744139","https://openalex.org/W2010500685","https://openalex.org/W2012084406","https://openalex.org/W2014195384","https://openalex.org/W2021122530","https://openalex.org/W2021928747","https://openalex.org/W2024058845","https://openalex.org/W2026726491","https://openalex.org/W2031291347","https://openalex.org/W2038497915","https://openalex.org/W2041163630","https://openalex.org/W2045460359","https://openalex.org/W2052556648","https://openalex.org/W2056532130","https://openalex.org/W2058171392","https://openalex.org/W2061223357","https://openalex.org/W2066413357","https://openalex.org/W2069273167","https://openalex.org/W2070505667","https://openalex.org/W2076749175","https://openalex.org/W2078421877","https://openalex.org/W2079191512","https://openalex.org/W2079195493","https://openalex.org/W2082207304","https://openalex.org/W2083800286","https://openalex.org/W2087899034","https://openalex.org/W2093694656","https://openalex.org/W2098840127","https://openalex.org/W2100837269","https://openalex.org/W2101108802","https://openalex.org/W2105367621","https://openalex.org/W2138548458","https://openalex.org/W2138646462","https://openalex.org/W2144775586","https://openalex.org/W2145028356","https://openalex.org/W2145908660","https://openalex.org/W2152463831","https://openalex.org/W2153396167","https://openalex.org/W2406517519","https://openalex.org/W2410825100","https://openalex.org/W2425349986","https://openalex.org/W2469482484","https://openalex.org/W4231575667","https://openalex.org/W4238542256","https://openalex.org/W4245958293"],"related_works":["https://openalex.org/W1996205796","https://openalex.org/W6902824970","https://openalex.org/W2409527034","https://openalex.org/W1992149936","https://openalex.org/W2004716655","https://openalex.org/W2587091765","https://openalex.org/W1996599102","https://openalex.org/W2082207304","https://openalex.org/W1810967695","https://openalex.org/W1980779026"],"abstract_inverted_index":{"Tenascin-C":[0],"(TNC)":[1],"is":[2,29],"an":[3],"oligomeric":[4],"glycoprotein":[5],"of":[6,42,55,84,111,130,140,161,173,184,188,199],"the":[7,24,48,82,97,102,112,125,131,141,150,159,162,169,174,185,189,197],"extracellular":[8],"matrix":[9],"with":[10,81],"several":[11],"distinct":[12],"isoforms":[13,193],"variably":[14],"expressed":[15],"during":[16],"embryogenesis,":[17],"tumorogenesis,":[18],"angiogenesis":[19],"and":[20,58,72,77,93,99,168,171,202],"wound":[21],"healing.":[22],"In":[23,152,181],"normal":[25,178],"human":[26,60],"adult,":[27],"TNC":[28,52,73,164,192],"found":[30,105],"in":[31,34,50,67,166,177],"large":[32,163],"concentrations":[33],"articular":[35,56],"cartilage,":[36],"suggesting":[37],"tissue-specific":[38],"function.":[39],"The":[40,127],"purpose":[41],"this":[43],"study":[44],"was":[45,121,134,147],"to":[46,106,157,196,205],"determine":[47],"specific":[49],"vitro":[51],"splicing":[53,128],"patterns":[54],"chondrocytes":[57,103],"a":[59,68,137],"chondrosarcoma":[61,167],"cell":[62],"line.":[63],"Cells":[64],"were":[65,79,104],"cultured":[66],"three-dimensional":[69],"bead":[70],"system":[71],"splice":[74],"variant":[75],"expression":[76,160],"distribution":[78],"examined":[80],"use":[83],"Western":[85],"blotting":[86],"techniques,":[87],"semi-quantitative":[88],"reverse-transcription":[89],"polymerase":[90],"chain":[91],"reaction":[92],"immunohistochemistry.":[94],"At":[95],"both":[96],"transcriptional":[98],"post-translational":[100],"levels,":[101],"express":[107],"significantly":[108],"higher":[109,138],"levels":[110],"smaller":[113,175],"220":[114],"kDa":[115,144],"isoform":[116,145,165,176],"(P":[117],"<":[118],"0.01),":[119],"which":[120,146],"predominantly":[122],"incorporated":[123],"into":[124,149],"matrix.":[126,180],"pattern":[129],"malignant":[132],"cells":[133],"characterized":[135],"by":[136],"proportion":[139],"larger":[142],"320":[143],"extruded":[148],"media.":[151],"vivo":[153],"studies":[154],"are":[155],"necessary":[156],"verify":[158],"production":[170],"integration":[172],"chondroid":[179],"addition,":[182],"elucidation":[183],"biologic":[186],"functions":[187],"two":[190],"major":[191],"may":[194],"lead":[195],"development":[198],"novel":[200],"diagnostic":[201],"therapeutic":[203],"approaches":[204],"chondrosarcoma.":[206]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}