{"id":"https://openalex.org/W1997994342","doi":"https://doi.org/10.1002/1097-0142(19860215)57:4<837::aid-cncr2820570425>3.0.co;2-o","title":"A clinical study of the pineal gland activity in oncologic patients","display_name":"A clinical study of the pineal gland activity in oncologic patients","publication_year":1986,"publication_date":"1986-02-15","ids":{"openalex":"https://openalex.org/W1997994342","doi":"https://doi.org/10.1002/1097-0142(19860215)57:4<837::aid-cncr2820570425>3.0.co;2-o","mag":"1997994342","pmid":"https://pubmed.ncbi.nlm.nih.gov/3943015"},"language":"en","primary_location":{"id":"doi:10.1002/1097-0142(19860215)57:4<837::aid-cncr2820570425>3.0.co;2-o","doi":"https://doi.org/10.1002/1097-0142(19860215)57:4<837::aid-cncr2820570425>3.0.co;2-o","is_oa":true,"landing_page_url":"https://doi.org/10.1002/1097-0142(19860215)57:4<837::aid-cncr2820570425>3.0.co;2-o","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2819860215%2957%3A4%3C837%3A%3AAID-CNCR2820570425%3E3.0.CO%3B2-O","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2819860215%2957%3A4%3C837%3A%3AAID-CNCR2820570425%3E3.0.CO%3B2-O","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113805869","display_name":"Paolo Lissoni","orcid":"https://orcid.org/0000-0002-5374-1350","observed_orcids":["https://orcid.org/0000-0002-5374-1350"]},"institutions":[{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Lissoni","raw_affiliation_strings":["Italian Auxological Centre, Piancavallo-Milan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian Auxological Centre, Piancavallo-Milan","institution_ids":["https://openalex.org/I4210134201"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087990801","display_name":"Simonetta Viviani","orcid":"https://orcid.org/0000-0002-5014-9546","observed_orcids":["https://orcid.org/0000-0002-5014-9546"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Simonetta Viviani","raw_affiliation_strings":["National Cancer Institute of Milan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Cancer Institute of Milan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014772726","display_name":"E. Bajetta","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Emilo Bajetta","raw_affiliation_strings":["National Cancer Institute of Milan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Cancer Institute of Milan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040934952","display_name":"Roberto Buzzoni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Buzzoni","raw_affiliation_strings":["National Cancer Institute of Milan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Cancer Institute of Milan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108421528","display_name":"Antonella Barreca","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonella Barreca","raw_affiliation_strings":["Chair of Endocrinology, University of Genoa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chair of Endocrinology, University of Genoa","institution_ids":["https://openalex.org/I83816512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002523211","display_name":"R Mauri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Raffaella Mauri","raw_affiliation_strings":["Italian Auxological Centre, Piancavallo-Milan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian Auxological Centre, Piancavallo-Milan","institution_ids":["https://openalex.org/I4210134201"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063793680","display_name":"M. Resentini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maurizio Resentini","raw_affiliation_strings":["Italian Auxological Centre, Piancavallo-Milan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian Auxological Centre, Piancavallo-Milan","institution_ids":["https://openalex.org/I4210134201"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068143882","display_name":"Francesco Carlo Morabito","orcid":"https://orcid.org/0000-0003-0734-9136","observed_orcids":["https://orcid.org/0000-0003-0734-9136"]},"institutions":[{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesco Morabito","raw_affiliation_strings":["Italian Auxological Centre, Piancavallo-Milan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Italian Auxological Centre, Piancavallo-Milan","institution_ids":["https://openalex.org/I4210134201"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086402435","display_name":"Daniele Esposti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Daniele Esposti","raw_affiliation_strings":["Institute of Human Physiology II, Faculty of Medicine, University of Milan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Human Physiology II, Faculty of Medicine, University of Milan","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111610457","display_name":"Germana Esposti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Germana Esposti","raw_affiliation_strings":["Chair of Chemotherapy, Faculty of Medicine, University of Milan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chair of Chemotherapy, Faculty of Medicine, University of Milan","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107639580","display_name":"FRANCO FRASCHINI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Franco Fraschini","raw_affiliation_strings":["Chair of Chemotherapy, Faculty of Medicine, University of Milan","Universita Degli Studi di Milano, Dipartimento di Farmacologia, Chemoterapia E. Tossicologia Medica, Cattedra di Chemioterapia, 20129 Milano, Via Vanvitelli 32, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chair of Chemotherapy, Faculty of Medicine, University of Milan","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Universita Degli Studi di Milano, Dipartimento di Farmacologia, Chemoterapia E. Tossicologia Medica, Cattedra di Chemioterapia, 20129 Milano, Via Vanvitelli 32, Italy","institution_ids":["https://openalex.org/I189158943"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5107639580"],"corresponding_institution_ids":["https://openalex.org/I189158943"],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":null,"fwci":3.6869,"has_fulltext":true,"cited_by_count":45,"citation_normalized_percentile":{"value":0.94126357,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"57","issue":"4","first_page":"837","last_page":"842"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12626","display_name":"Cancer, Stress, Anesthesia, and Immune Response","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11144","display_name":"melanin and skin pigmentation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pineal-gland","display_name":"pineal gland","score":0.9900000095367432},{"id":"https://openalex.org/keywords/melatonin","display_name":"melatonin","score":0.9539999961853027},{"id":"https://openalex.org/keywords/serum-melatonin-levels","display_name":"serum melatonin","score":0.906000018119812},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.7649999856948853},{"id":"https://openalex.org/keywords/tumor-growth-control","display_name":"tumor growth control","score":0.6710000038146973},{"id":"https://openalex.org/keywords/cancer-patients","display_name":"cancer patients","score":0.7910000085830688},{"id":"https://openalex.org/keywords/chemotherapy-effects","display_name":"chemotherapy effects","score":0.7260000109672546}],"concepts":[{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.987706184387207},{"id":"https://openalex.org/C2780059843","wikidata":"https://www.wikidata.org/wiki/Q198654","display_name":"Pineal gland","level":3,"score":0.9407804012298584},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7086721062660217},{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.6274756193161011},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5812740921974182},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.540781557559967},{"id":"https://openalex.org/C135343436","wikidata":"https://www.wikidata.org/wiki/Q170406","display_name":"Rhythm","level":2,"score":0.5174944400787354},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4895942807197571}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008550","descriptor_name":"Melatonin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D010870","descriptor_name":"Pineal Gland","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/1097-0142(19860215)57:4<837::aid-cncr2820570425>3.0.co;2-o","doi":"https://doi.org/10.1002/1097-0142(19860215)57:4<837::aid-cncr2820570425>3.0.co;2-o","is_oa":true,"landing_page_url":"https://doi.org/10.1002/1097-0142(19860215)57:4<837::aid-cncr2820570425>3.0.co;2-o","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2819860215%2957%3A4%3C837%3A%3AAID-CNCR2820570425%3E3.0.CO%3B2-O","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},{"id":"pmid:3943015","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3943015","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/1097-0142(19860215)57:4<837::aid-cncr2820570425>3.0.co;2-o","doi":"https://doi.org/10.1002/1097-0142(19860215)57:4<837::aid-cncr2820570425>3.0.co;2-o","is_oa":true,"landing_page_url":"https://doi.org/10.1002/1097-0142(19860215)57:4<837::aid-cncr2820570425>3.0.co;2-o","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2819860215%2957%3A4%3C837%3A%3AAID-CNCR2820570425%3E3.0.CO%3B2-O","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1997994342.pdf","grobid_xml":"https://content.openalex.org/works/W1997994342.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W273889473","https://openalex.org/W1483633408","https://openalex.org/W1541345471","https://openalex.org/W1570031919","https://openalex.org/W1608288887","https://openalex.org/W1971541825","https://openalex.org/W1971644718","https://openalex.org/W1983665527","https://openalex.org/W1987380712","https://openalex.org/W1988189248","https://openalex.org/W1990071979","https://openalex.org/W1994710209","https://openalex.org/W2001600473","https://openalex.org/W2005752116","https://openalex.org/W2005919702","https://openalex.org/W2011139962","https://openalex.org/W2013943621","https://openalex.org/W2040614990","https://openalex.org/W2062190231","https://openalex.org/W2070916044","https://openalex.org/W2071756336","https://openalex.org/W2077129521","https://openalex.org/W2080191063","https://openalex.org/W2130306865","https://openalex.org/W2144349079","https://openalex.org/W2157950502","https://openalex.org/W2333249756","https://openalex.org/W2397107637","https://openalex.org/W2410667685","https://openalex.org/W4205964204"],"related_works":["https://openalex.org/W2088526645","https://openalex.org/W2414707710","https://openalex.org/W2006689021","https://openalex.org/W2398104261","https://openalex.org/W3092004357","https://openalex.org/W2032148808","https://openalex.org/W2765809655","https://openalex.org/W175628731","https://openalex.org/W2161441499","https://openalex.org/W2427188350"],"abstract_inverted_index":{"It":[0,109],"has":[1,68],"been":[2,39,69],"known":[3],"for":[4],"many":[5],"years":[6],"that":[7],"the":[8,21,25,42,55,58,72,75,83,120],"pineal":[9,26],"gland":[10,27],"is":[11],"involved":[12],"in":[13,28,45,95],"regulating":[14],"tumor":[15,59],"growth.":[16],"In":[17],"order":[18],"to":[19,113],"evaluate":[20],"functional":[22],"activity":[23],"of":[24,51,54,57,61,65,80,91,101,122],"neoplastic":[29],"diseases,":[30],"melatonin":[31,92,103,116],"serum":[32,102],"levels":[33,79,117],"and":[34,60,82],"its":[35,62],"light/dark":[36,89],"rhythm":[37,90],"have":[38],"determined":[40],"with":[41,77,85,124],"RIA":[43],"method":[44],"patients":[46,123],"affected":[47],"by":[48],"various":[49],"forms":[50],"tumor.":[52],"Irrespectively":[53],"type":[56],"localization,":[63],"existence":[64],"two":[66],"subpopulations":[67],"observed":[70],"within":[71],"oncologic":[73],"patients,":[74],"former":[76],"normal":[78],"melatonin,":[81],"latter":[84],"high":[86],"ones.":[87],"The":[88],"was":[93,105],"anomalous":[94],"some":[96],"cases.":[97],"An":[98],"evident":[99],"decrease":[100],"values":[104],"seen":[106],"after":[107],"chemotherapy.":[108],"might":[110],"be":[111],"interesting":[112],"establish":[114],"whether":[115],"may":[118],"conditionate":[119],"prognosis":[121],"cancer.":[125]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}