{"id":"https://openalex.org/W1997843665","doi":"https://doi.org/10.1016/j.neurad.2010.08.001","title":"Dynamic perfusion-CT assessment of early changes in blood brain barrier permeability of acute ischaemic stroke patients","display_name":"Dynamic perfusion-CT assessment of early changes in blood brain barrier permeability of acute ischaemic stroke patients","publication_year":2010,"publication_date":"2010-10-15","ids":{"openalex":"https://openalex.org/W1997843665","doi":"https://doi.org/10.1016/j.neurad.2010.08.001","mag":"1997843665","pmid":"https://pubmed.ncbi.nlm.nih.gov/20950860"},"language":"en","primary_location":{"id":"doi:10.1016/j.neurad.2010.08.001","doi":"https://doi.org/10.1016/j.neurad.2010.08.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neurad.2010.08.001","pdf_url":null,"source":{"id":"https://openalex.org/S45717877","display_name":"Journal of Neuroradiology","issn_l":"0150-9861","issn":["0150-9861","1773-0406"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroradiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019072762","display_name":"Jan Willem Dankbaar","orcid":"https://orcid.org/0000-0003-4646-9587","observed_orcids":["https://orcid.org/0000-0003-4646-9587"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL","US"],"is_corresponding":false,"raw_author_name":"J.W. Dankbaar","raw_affiliation_strings":["University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, USA","University Medical Center Utrecht, Department of Radiology, The Netherlands","University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"University Medical Center Utrecht, Department of Radiology, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]},{"raw_affiliation_string":"University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, United States","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061093158","display_name":"Jason Hom","orcid":"https://orcid.org/0000-0002-8404-5796","observed_orcids":["https://orcid.org/0000-0002-8404-5796"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Hom","raw_affiliation_strings":["University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, United States","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":null,"display_name":"T. Schneider","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131230","display_name":"Philips (United States)","ror":"https://ror.org/03kw6wr76","country_code":"US","type":"company","lineage":["https://openalex.org/I4210122849","https://openalex.org/I4210131230"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T. Schneider","raw_affiliation_strings":["Philips Healthcare, CT Clinical Science Group and Philips Research North America, Clinical Sites Research Program, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Philips Healthcare, CT Clinical Science Group and Philips Research North America, Clinical Sites Research Program, United States","institution_ids":["https://openalex.org/I4210131230"]}]},{"author_position":"middle","author":{"id":null,"display_name":"S.-C. Cheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S.-C. Cheng","raw_affiliation_strings":["University of California, Department of Epidemiology and Biostatistics, San Francisco, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Department of Epidemiology and Biostatistics, San Francisco, United States","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018623004","display_name":"Joerg Bredno","orcid":"https://orcid.org/0000-0002-2302-2339","observed_orcids":["https://orcid.org/0000-0002-2302-2339"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I4210131230","display_name":"Philips (United States)","ror":"https://ror.org/03kw6wr76","country_code":"US","type":"company","lineage":["https://openalex.org/I4210122849","https://openalex.org/I4210131230"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Bredno","raw_affiliation_strings":["Philips Healthcare, CT Clinical Science Group and Philips Research North America, Clinical Sites Research Program, United States","University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Philips Healthcare, CT Clinical Science Group and Philips Research North America, Clinical Sites Research Program, United States","institution_ids":["https://openalex.org/I4210131230"]},{"raw_affiliation_string":"University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, United States","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087625184","display_name":"Benison C. Lau","orcid":"https://orcid.org/0009-0006-3248-6123","observed_orcids":["https://orcid.org/0009-0006-3248-6123"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B.C. Lau","raw_affiliation_strings":["University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, United States","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055365141","display_name":"Irene C. van der Schaaf","orcid":"https://orcid.org/0000-0002-2588-264X","observed_orcids":["https://orcid.org/0000-0002-2588-264X"]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"I.C. van der Schaaf","raw_affiliation_strings":["University Medical Center Utrecht, Department of Radiology, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Medical Center Utrecht, Department of Radiology, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052087773","display_name":"Max Wintermark","orcid":"https://orcid.org/0000-0002-6726-3951","observed_orcids":["https://orcid.org/0000-0002-6726-3951"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"M. Wintermark","raw_affiliation_strings":["University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, United States","University of Virginia, Department of Radiology, Neuroradiology Division, 1st Floor, Room 1011, 1215, Lee Street-New Hospital, P.O. Box 800170, Charlottesville, VA 22908-0170, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, United States","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"University of Virginia, Department of Radiology, Neuroradiology Division, 1st Floor, Room 1011, 1215, Lee Street-New Hospital, P.O. Box 800170, Charlottesville, VA 22908-0170, United States","institution_ids":["https://openalex.org/I51556381"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5052087773"],"corresponding_institution_ids":["https://openalex.org/I180670191","https://openalex.org/I51556381"],"apc_list":{"value":4040,"currency":"USD","value_usd":4040},"apc_paid":null,"fwci":1.1637,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.78787719,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"38","issue":"3","first_page":"161","last_page":"166"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.7871000170707703,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.7871000170707703,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.1956000030040741,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blood-brain-barrier-permeability","display_name":"blood-brain barrier permeability","score":0.9070000052452087},{"id":"https://openalex.org/keywords/acute-ischemic-stroke","display_name":"acute ischemic stroke","score":0.9900000095367432},{"id":"https://openalex.org/keywords/ct-perfusion","display_name":"CT perfusion","score":0.8259999752044678},{"id":"https://openalex.org/keywords/hemorrhagic-transformation","display_name":"hemorrhagic transformation","score":0.9750000238418579},{"id":"https://openalex.org/keywords/collateral-circulation","display_name":"collateral circulation","score":0.7990000247955322},{"id":"https://openalex.org/keywords/infarct-core","display_name":"infarct core","score":0.9160000085830688},{"id":"https://openalex.org/keywords/patlak-model","display_name":"Patlak model","score":0.8659999966621399},{"id":"https://openalex.org/keywords/stroke-severity","display_name":"stroke severity","score":0.7599999904632568},{"id":"https://openalex.org/keywords/vascular-risk-factors","display_name":"vascular risk factors","score":0.906000018119812}],"concepts":[{"id":"https://openalex.org/C2780577055","wikidata":"https://www.wikidata.org/wiki/Q2069532","display_name":"Penumbra","level":3,"score":0.9312583208084106},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8374816179275513},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.6566348075866699},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.579041063785553},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.57850581407547},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5658432841300964},{"id":"https://openalex.org/C2776599846","wikidata":"https://www.wikidata.org/wiki/Q5145979","display_name":"Collateral circulation","level":2,"score":0.5282145142555237},{"id":"https://openalex.org/C3018755981","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischaemic stroke","level":3,"score":0.5046650171279907},{"id":"https://openalex.org/C135691158","wikidata":"https://www.wikidata.org/wiki/Q7168308","display_name":"Perfusion scanning","level":3,"score":0.4848126471042633},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3475401699542999},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.3287602663040161},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001812","descriptor_name":"Blood-Brain Barrier","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002533","descriptor_name":"Cerebral Angiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D003287","descriptor_name":"Contrast Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011857","descriptor_name":"Radiographic Image Interpretation, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.neurad.2010.08.001","doi":"https://doi.org/10.1016/j.neurad.2010.08.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neurad.2010.08.001","pdf_url":null,"source":{"id":"https://openalex.org/S45717877","display_name":"Journal of Neuroradiology","issn_l":"0150-9861","issn":["0150-9861","1773-0406"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroradiology","raw_type":"journal-article"},{"id":"pmid:20950860","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20950860","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuroradiology = Journal de neuroradiologie","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.7799999713897705,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320333854","display_name":"Philips Research Americas","ror":null},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1921106608","https://openalex.org/W1971777852","https://openalex.org/W1973215406","https://openalex.org/W1979482187","https://openalex.org/W1998869669","https://openalex.org/W1998907224","https://openalex.org/W2000351290","https://openalex.org/W2035228112","https://openalex.org/W2046724625","https://openalex.org/W2053752925","https://openalex.org/W2053877781","https://openalex.org/W2054789729","https://openalex.org/W2060066888","https://openalex.org/W2064342657","https://openalex.org/W2068780254","https://openalex.org/W2074858865","https://openalex.org/W2075897459","https://openalex.org/W2080190646","https://openalex.org/W2082497790","https://openalex.org/W2088303839","https://openalex.org/W2092078486","https://openalex.org/W2093460922","https://openalex.org/W2115018111","https://openalex.org/W2122998820","https://openalex.org/W2134657255","https://openalex.org/W2148656951","https://openalex.org/W2153837600","https://openalex.org/W2154227298","https://openalex.org/W2158528601","https://openalex.org/W2159899308","https://openalex.org/W2339319747","https://openalex.org/W4210973470"],"related_works":["https://openalex.org/W2075100313","https://openalex.org/W2134657255","https://openalex.org/W2017248600","https://openalex.org/W2091228853","https://openalex.org/W1975190311","https://openalex.org/W141075433","https://openalex.org/W2044247537","https://openalex.org/W2035228112","https://openalex.org/W7096128107","https://openalex.org/W1967218812"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}