{"id":"https://openalex.org/W1997802665","doi":"https://doi.org/10.1097/01.wnr.0000201504.23255.bc","title":"Mesencephalic astrocyte-derived neurotrophic factor enhances nigral \u03b3-aminobutyric acid release","display_name":"Mesencephalic astrocyte-derived neurotrophic factor enhances nigral \u03b3-aminobutyric acid release","publication_year":2006,"publication_date":"2006-02-06","ids":{"openalex":"https://openalex.org/W1997802665","doi":"https://doi.org/10.1097/01.wnr.0000201504.23255.bc","mag":"1997802665","pmid":"https://pubmed.ncbi.nlm.nih.gov/16462600"},"language":"en","primary_location":{"id":"doi:10.1097/01.wnr.0000201504.23255.bc","doi":"https://doi.org/10.1097/01.wnr.0000201504.23255.bc","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.wnr.0000201504.23255.bc","pdf_url":null,"source":{"id":"https://openalex.org/S121278948","display_name":"Neuroreport","issn_l":"0959-4965","issn":["0959-4965","1473-558X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroReport","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039517524","display_name":"Chunyi Zhou","orcid":"https://orcid.org/0000-0003-2290-9234","observed_orcids":["https://orcid.org/0000-0003-2290-9234","https://orcid.org/0000-0003-0081-0946"]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chunyi Zhou","raw_affiliation_strings":["Department of Anesthesiology, New Jersey Medical School, Newark, New Jersey, USA","Departments of Anesthesiology","Pharmacology and Physiology, New Jersey Medical School, Newark, New Jersey, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, New Jersey Medical School, Newark, New Jersey, USA","institution_ids":["https://openalex.org/I4402554120"]},{"raw_affiliation_string":"Departments of Anesthesiology","institution_ids":[]},{"raw_affiliation_string":"Pharmacology and Physiology, New Jersey Medical School, Newark, New Jersey, USA","institution_ids":["https://openalex.org/I4402554120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067786455","display_name":"Cheng Xiao","orcid":"https://orcid.org/0000-0001-9649-7450","observed_orcids":["https://orcid.org/0000-0001-9649-7450"]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cheng Xiao","raw_affiliation_strings":["Departments of Anesthesiology","Pharmacology and Physiology, New Jersey Medical School, Newark, New Jersey, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Anesthesiology","institution_ids":[]},{"raw_affiliation_string":"Pharmacology and Physiology, New Jersey Medical School, Newark, New Jersey, USA","institution_ids":["https://openalex.org/I4402554120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113588965","display_name":"John W. Commissiong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John W. Commissiong","raw_affiliation_strings":["Neurotrophics Inc., Mississauge, Ontario"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurotrophics Inc., Mississauge, Ontario","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055716619","display_name":"Kre\u0161imir Krnjevi\u0107","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Kre\u0161imir Krnjevi\u0107","raw_affiliation_strings":["Physiology Department, McGill University, Montreal, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physiology Department, McGill University, Montreal, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112837302","display_name":"Jiang Hong Ye","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jiang Hong Ye","raw_affiliation_strings":["Departments of Anesthesiology","Pharmacology and Physiology, New Jersey Medical School, Newark, New Jersey, USA","and requests for reprints to Jiang Hong Ye, Department of Anesthesiology, New Jersey Medical School (UMDNJ), 185 South Orange Avenue, Newark, NJ 07103-2714, USA","requests for reprints to Jiang Hong Ye, Department of Anesthesiology, New Jersey Medical School (UMDNJ), 185 South Orange Avenue, Newark, NJ 07103-2714, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Anesthesiology","institution_ids":[]},{"raw_affiliation_string":"Pharmacology and Physiology, New Jersey Medical School, Newark, New Jersey, USA","institution_ids":["https://openalex.org/I4402554120"]},{"raw_affiliation_string":"and requests for reprints to Jiang Hong Ye, Department of Anesthesiology, New Jersey Medical School (UMDNJ), 185 South Orange Avenue, Newark, NJ 07103-2714, USA","institution_ids":["https://openalex.org/I4402554120"]},{"raw_affiliation_string":"requests for reprints to Jiang Hong Ye, Department of Anesthesiology, New Jersey Medical School (UMDNJ), 185 South Orange Avenue, Newark, NJ 07103-2714, USA","institution_ids":["https://openalex.org/I4402554120"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5112837302"],"corresponding_institution_ids":["https://openalex.org/I4402554120"],"apc_list":null,"apc_paid":null,"fwci":1.0751,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.70381726,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"17","issue":"3","first_page":"293","last_page":"297"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.8598999977111816,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.8598999977111816,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.07660000026226044,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.022700000554323196,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/manf","display_name":"MANF","score":0.996999979019165},{"id":"https://openalex.org/keywords/gaba-release","display_name":"GABA release","score":0.7559999823570251},{"id":"https://openalex.org/keywords/gaba-a-receptor","display_name":"GABAA receptor","score":0.777999997138977},{"id":"https://openalex.org/keywords/inhibitory-postsynaptic-currents","display_name":"inhibitory postsynaptic currents","score":0.9319999814033508},{"id":"https://openalex.org/keywords/substantia-nigra-pars-compacta","display_name":"substantia nigra pars compacta","score":0.9789999723434448},{"id":"https://openalex.org/keywords/dopaminergic-neurons","display_name":"dopaminergic neurons","score":0.921999990940094},{"id":"https://openalex.org/keywords/neuronal-survival","display_name":"neuronal survival","score":0.6110000014305115},{"id":"https://openalex.org/keywords/paired-pulse-ratio","display_name":"paired-pulse ratio","score":0.8180000185966492},{"id":"https://openalex.org/keywords/miniature-ipscs","display_name":"miniature IPSCs","score":0.8539999723434448}],"concepts":[{"id":"https://openalex.org/C2777542381","wikidata":"https://www.wikidata.org/wiki/Q502961","display_name":"Astrocyte","level":3,"score":0.8043904304504395},{"id":"https://openalex.org/C160539049","wikidata":"https://www.wikidata.org/wiki/Q3064187","display_name":"Neurotrophic factors","level":3,"score":0.6688264012336731},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6509963274002075},{"id":"https://openalex.org/C2779414652","wikidata":"https://www.wikidata.org/wiki/Q3604505","display_name":"Aminobutyric acid","level":3,"score":0.6007331013679504},{"id":"https://openalex.org/C2778790584","wikidata":"https://www.wikidata.org/wiki/Q123045","display_name":"Brain-derived neurotrophic factor","level":4,"score":0.5632439851760864},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.4984734058380127},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4465491771697998},{"id":"https://openalex.org/C92020748","wikidata":"https://www.wikidata.org/wiki/Q420457","display_name":"Neurotrophin","level":3,"score":0.43461525440216064},{"id":"https://openalex.org/C185856081","wikidata":"https://www.wikidata.org/wiki/Q14916286","display_name":"Glial cell line-derived neurotrophic factor","level":4,"score":0.4257138967514038},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3396996855735779},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3240332007408142},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21163630485534668},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001640","descriptor_name":"Bicuculline","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004307","descriptor_name":"Dose-Response Relationship, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005680","descriptor_name":"gamma-Aminobutyric Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008564","descriptor_name":"Membrane Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008564","descriptor_name":"Membrane Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008564","descriptor_name":"Membrane Potentials","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D008636","descriptor_name":"Mesencephalon","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018408","descriptor_name":"Patch-Clamp Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018491","descriptor_name":"Dopamine Agonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018756","descriptor_name":"GABA Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D019257","descriptor_name":"Quinpirole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D020875","descriptor_name":"Enkephalin, Ala(2)-MePhe(4)-Gly(5)-","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051100","descriptor_name":"Glial Cell Line-Derived Neurotrophic Factor","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/01.wnr.0000201504.23255.bc","doi":"https://doi.org/10.1097/01.wnr.0000201504.23255.bc","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.wnr.0000201504.23255.bc","pdf_url":null,"source":{"id":"https://openalex.org/S121278948","display_name":"Neuroreport","issn_l":"0959-4965","issn":["0959-4965","1473-558X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroReport","raw_type":"journal-article"},{"id":"pmid:16462600","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16462600","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroreport","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1394581091","display_name":null,"funder_award_id":"AT001182","funder_id":"https://openalex.org/F4320337593","funder_display_name":"National Center for Complementary and Integrative Health"},{"id":"https://openalex.org/G2661628120","display_name":null,"funder_award_id":"AA11989","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G6978924823","display_name":"Neurobiol mechanism/acupuncture therapy/alcoholism","funder_award_id":"R21AT001182","funder_id":"https://openalex.org/F4320337593","funder_display_name":"National Center for Complementary and Integrative Health"},{"id":"https://openalex.org/G8585789348","display_name":"ETHANOL EFFECTS ON GLYCINE RECEPTOR/CHANNEL FUNCTION","funder_award_id":"R01AA011989","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"}],"funders":[{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"},{"id":"https://openalex.org/F4320337593","display_name":"National Center for Complementary and Integrative Health","ror":"https://ror.org/00190t495"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1507802589","https://openalex.org/W1586815960","https://openalex.org/W1764026126","https://openalex.org/W1929519779","https://openalex.org/W1985114553","https://openalex.org/W2002529395","https://openalex.org/W2009632489","https://openalex.org/W2022015307","https://openalex.org/W2027915766","https://openalex.org/W2047098181","https://openalex.org/W2055775269","https://openalex.org/W2069866761","https://openalex.org/W2136690680","https://openalex.org/W2143959688","https://openalex.org/W2155166279"],"related_works":["https://openalex.org/W2126967674","https://openalex.org/W2785262129","https://openalex.org/W2107639627","https://openalex.org/W4310071250","https://openalex.org/W2023505129","https://openalex.org/W2977407748","https://openalex.org/W2290493017","https://openalex.org/W2069866761","https://openalex.org/W2141240317","https://openalex.org/W2729799602"],"abstract_inverted_index":{"Mesencephalic":[0],"astrocyte-derived":[1,12],"neurotrophic":[2],"factor":[3],"(MANF)":[4],"-":[5],"one":[6],"of":[7,11,18,21,35,51,57,68,85,113],"a":[8],"new":[9],"class":[10],"human":[13],"proteins--selectively":[14],"promotes":[15],"the":[16,22,26,52,66,73,83],"survival":[17],"dopamine":[19,49,123],"neurons":[20,50],"ventral":[23],"midbrain.":[24],"Using":[25],"whole-cell":[27],"clamp":[28],"technique,":[29],"we":[30],"looked":[31],"for":[32],"acute":[33],"effects":[34],"MANF":[36,64,81,100],"on":[37,104,122],"gamma-aminobutyric":[38],"acid":[39],"type":[40],"A":[41],"(GABAA)":[42],"receptor-mediated":[43],"inhibitory":[44],"postsynaptic":[45],"currents":[46,105],"(IPSCs)":[47],"in":[48,96],"substantia":[53],"nigra":[54],"pars":[55],"compacta":[56],"6":[58],"to":[59,118],"15-day-old":[60],"rats.":[61],"In":[62,77],"slices,":[63],"increased":[65,82],"amplitude":[67],"evoked":[69],"IPSCs":[70],"and":[71,87,95],"decreased":[72],"paired":[74],"pulse":[75],"ratio.":[76],"mechanically":[78],"dissociated":[79,98],"cells,":[80],"frequency":[84],"spontaneous":[86],"miniature":[88],"IPSCs,":[89],"without":[90],"changing":[91],"their":[92],"mean":[93],"amplitudes;":[94],"enzymatically":[97],"neurons,":[99],"had":[101],"no":[102],"effect":[103],"induced":[106],"by":[107],"exogenous":[108],"GABA.":[109],"The":[110],"presynaptic":[111],"enhancement":[112],"GABAergic":[114],"inhibition":[115],"may":[116],"contribute":[117],"MANF's":[119],"protective":[120],"action":[121],"cells.":[124]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}