{"id":"https://openalex.org/W1997769129","doi":"https://doi.org/10.1111/j.1749-6632.1968.tb19070.x","title":"A BRIEF REVIEW OF THE DEVELOPMENT OF DIAZOXIDE AS AN ANTIHYPERTENSIVE AGENT","display_name":"A BRIEF REVIEW OF THE DEVELOPMENT OF DIAZOXIDE AS AN ANTIHYPERTENSIVE AGENT","publication_year":1968,"publication_date":"1968-04-01","ids":{"openalex":"https://openalex.org/W1997769129","doi":"https://doi.org/10.1111/j.1749-6632.1968.tb19070.x","mag":"1997769129","pmid":"https://pubmed.ncbi.nlm.nih.gov/5243883"},"language":"en","primary_location":{"id":"doi:10.1111/j.1749-6632.1968.tb19070.x","doi":"https://doi.org/10.1111/j.1749-6632.1968.tb19070.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1968.tb19070.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060749779","display_name":"Alan A. Rubin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alan A. Rubin","raw_affiliation_strings":["Endo Labs., Garden City, N. Y","Scheming Corporation, Bloomfield, N. J"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endo Labs., Garden City, N. Y","institution_ids":[]},{"raw_affiliation_string":"Scheming Corporation, Bloomfield, N. J","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113535294","display_name":"Richard M. Taylor","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard M. Taylor","raw_affiliation_strings":["Deceased","Scheming Corporation, Bloomfield, N. J"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Deceased","institution_ids":[]},{"raw_affiliation_string":"Scheming Corporation, Bloomfield, N. J","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112727929","display_name":"Franklin E. Roth","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Franklin E. Roth","raw_affiliation_strings":["Scheming Corporation, Bloomfield, N. J"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scheming Corporation, Bloomfield, N. J","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":null,"fwci":2.477,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.87277811,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"150","issue":"2","first_page":"457","last_page":"460"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.8407999873161316,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.8407999873161316,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14275","display_name":"Historical Medical Research and Treatments","score":0.11029999703168869,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12990","display_name":"Medical History and Innovations","score":0.028999999165534973,"subfield":{"id":"https://openalex.org/subfields/1202","display_name":"History"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diazoxide","display_name":"diazoxide","score":0.9980000257492065},{"id":"https://openalex.org/keywords/antihypertensive-drugs","display_name":"antihypertensive drugs","score":0.9660000205039978},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.7789999842643738},{"id":"https://openalex.org/keywords/drug-development","display_name":"drug development","score":0.6140000224113464},{"id":"https://openalex.org/keywords/potassium-channel-openers","display_name":"potassium channel openers","score":0.6460000276565552}],"concepts":[{"id":"https://openalex.org/C2778348171","wikidata":"https://www.wikidata.org/wiki/Q167037","display_name":"Corporation","level":2,"score":0.7119420170783997},{"id":"https://openalex.org/C2780708616","wikidata":"https://www.wikidata.org/wiki/Q193866","display_name":"Annals","level":2,"score":0.5368301272392273},{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.4852416515350342},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.46016284823417664},{"id":"https://openalex.org/C2779872217","wikidata":"https://www.wikidata.org/wiki/Q420009","display_name":"Diazoxide","level":3,"score":0.4174623489379883},{"id":"https://openalex.org/C74916050","wikidata":"https://www.wikidata.org/wiki/Q841090","display_name":"Classics","level":1,"score":0.3301737606525421},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3222264051437378},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.2568895220756531},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2336532473564148},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.17894452810287476},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.16695266962051392},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001158","descriptor_name":"Arteries","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003981","descriptor_name":"Diazoxide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004231","descriptor_name":"Diuresis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007684","descriptor_name":"Kidney Tubules","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009130","descriptor_name":"Muscle, Smooth","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014655","descriptor_name":"Vascular Resistance","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014667","descriptor_name":"Vasopressins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1749-6632.1968.tb19070.x","doi":"https://doi.org/10.1111/j.1749-6632.1968.tb19070.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1968.tb19070.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:5243883","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5243883","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1895862748","https://openalex.org/W1979123502","https://openalex.org/W2007393139","https://openalex.org/W2022352208","https://openalex.org/W2033742616","https://openalex.org/W2071649264","https://openalex.org/W2073697186","https://openalex.org/W2076646754","https://openalex.org/W2089754759","https://openalex.org/W2170573990","https://openalex.org/W2171254609","https://openalex.org/W2415765182","https://openalex.org/W2418713696","https://openalex.org/W4406965190"],"related_works":["https://openalex.org/W2414393992","https://openalex.org/W1974933395","https://openalex.org/W2079947306","https://openalex.org/W1994990421","https://openalex.org/W2140547903","https://openalex.org/W2443307623","https://openalex.org/W4255790126","https://openalex.org/W4231203974","https://openalex.org/W2105427384","https://openalex.org/W1976621742"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}