{"id":"https://openalex.org/W1997704623","doi":"https://doi.org/10.1016/s0014-5793(03)01396-6","title":"Genomic expression pattern in Saccharomyces cerevisiae cells in response to high hydrostatic pressure","display_name":"Genomic expression pattern in Saccharomyces cerevisiae cells in response to high hydrostatic pressure","publication_year":2003,"publication_date":"2003-12-04","ids":{"openalex":"https://openalex.org/W1997704623","doi":"https://doi.org/10.1016/s0014-5793(03)01396-6","mag":"1997704623","pmid":"https://pubmed.ncbi.nlm.nih.gov/14706843"},"language":"en","primary_location":{"id":"doi:10.1016/s0014-5793(03)01396-6","doi":"https://doi.org/10.1016/s0014-5793(03)01396-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0014-5793(03)01396-6","pdf_url":null,"source":{"id":"https://openalex.org/S104830714","display_name":"FEBS Letters","issn_l":"0014-5793","issn":["0014-5793","1873-3468"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEBS Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022788967","display_name":"Patr\u00edcia Machado Bueno Fernandes","orcid":"https://orcid.org/0000-0003-2695-3638","observed_orcids":["https://orcid.org/0000-0003-2695-3638"]},"institutions":[{"id":"https://openalex.org/I51235708","display_name":"Universidade Federal do Esp\u00edrito Santo","ror":"https://ror.org/05sxf4h28","country_code":"BR","type":"education","lineage":["https://openalex.org/I51235708"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Patricia M.B. Fernandes","raw_affiliation_strings":["Departamento de Ci\u00eancias Fisiol\u00f3gicas, CBM, UFES, 29090-040, ES, Vit\u00f3ria, Brazil. pat@npd.ufes.br","Departamento de Ci\u00eancias Fisiol\u00f3gicas, CBM, UFES, 29090-040, Vit\u00f3ria, ES, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Ci\u00eancias Fisiol\u00f3gicas, CBM, UFES, 29090-040, ES, Vit\u00f3ria, Brazil. pat@npd.ufes.br","institution_ids":["https://openalex.org/I51235708"]},{"raw_affiliation_string":"Departamento de Ci\u00eancias Fisiol\u00f3gicas, CBM, UFES, 29090-040, Vit\u00f3ria, ES, Brazil","institution_ids":["https://openalex.org/I51235708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013463238","display_name":"Tatiana Domitrovic","orcid":"https://orcid.org/0000-0001-9196-9412","observed_orcids":["https://orcid.org/0000-0001-9196-9412"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Tatiana Domitrovic","raw_affiliation_strings":["Departamento de Bioqu\u0131\u0301mica Me\u0301dica, ICB/CCS, UFRJ, Rio de Janeiro, RJ, Brazil","Departamento de Bioqu\u0131\u0301mica M\u00e9dica, ICB/CCS, UFRJ, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u0131\u0301mica Me\u0301dica, ICB/CCS, UFRJ, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]},{"raw_affiliation_string":"Departamento de Bioqu\u0131\u0301mica M\u00e9dica, ICB/CCS, UFRJ, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042850506","display_name":"Camilla M. Kao","orcid":"https://orcid.org/0000-0002-5743-5246","observed_orcids":["https://orcid.org/0000-0002-5743-5246"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Camilla M. Kao","raw_affiliation_strings":["Department of Chemical Engineering, Stanford University, Stanford, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Stanford University, Stanford, CA, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030477433","display_name":"Eleonora Kurtenbach","orcid":"https://orcid.org/0000-0002-2141-518X","observed_orcids":["https://orcid.org/0000-0002-2141-518X"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Eleonora Kurtenbach","raw_affiliation_strings":["Departamento de Bioqu\u0131\u0301mica Me\u0301dica, ICB/CCS, UFRJ, Rio de Janeiro, RJ, Brazil","Departamento de Bioqu\u0131\u0301mica M\u00e9dica, ICB/CCS, UFRJ, Rio de Janeiro, RJ, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioqu\u0131\u0301mica Me\u0301dica, ICB/CCS, UFRJ, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]},{"raw_affiliation_string":"Departamento de Bioqu\u0131\u0301mica M\u00e9dica, ICB/CCS, UFRJ, Rio de Janeiro, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5022788967"],"corresponding_institution_ids":["https://openalex.org/I51235708"],"apc_list":{"value":3980,"currency":"USD","value_usd":3980},"apc_paid":null,"fwci":2.6435,"has_fulltext":false,"cited_by_count":127,"citation_normalized_percentile":{"value":0.89944838,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"556","issue":"1-3","first_page":"153","last_page":"160"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9057999849319458,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9057999849319458,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":0.06599999964237213,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.9150000214576721},{"id":"https://openalex.org/keywords/high-hydrostatic-pressure","display_name":"high hydrostatic pressure","score":0.8970000147819519},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.6990000009536743},{"id":"https://openalex.org/keywords/stress-response","display_name":"stress response","score":0.9399999976158142},{"id":"https://openalex.org/keywords/pressure-adaptation","display_name":"pressure adaptation","score":0.6420000195503235},{"id":"https://openalex.org/keywords/carbohydrate-metabolism","display_name":"carbohydrate metabolism","score":0.9459999799728394},{"id":"https://openalex.org/keywords/cell-cycle","display_name":"cell cycle","score":0.8270000219345093},{"id":"https://openalex.org/keywords/protein-synthesis","display_name":"protein synthesis","score":0.9850000143051147},{"id":"https://openalex.org/keywords/uncharacterized-genes","display_name":"uncharacterized genes","score":0.8109999895095825},{"id":"https://openalex.org/keywords/yeast","display_name":"yeast","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.895077109336853},{"id":"https://openalex.org/C2910081258","wikidata":"https://www.wikidata.org/wiki/Q177807","display_name":"Hydrostatic pressure","level":2,"score":0.7591198682785034},{"id":"https://openalex.org/C6856738","wikidata":"https://www.wikidata.org/wiki/Q331672","display_name":"Protein expression","level":3,"score":0.4568865895271301},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.424969345331192},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3810526728630066},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3719716966152191},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.35329723358154297},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.32429808378219604},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.2422516644001007},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21273553371429443},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1701655089855194},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.09476050734519958}],"mesh":[{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006874","descriptor_name":"Hydrostatic Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016366","descriptor_name":"Open Reading Frames","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016681","descriptor_name":"Genome, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0014-5793(03)01396-6","doi":"https://doi.org/10.1016/s0014-5793(03)01396-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0014-5793(03)01396-6","pdf_url":null,"source":{"id":"https://openalex.org/S104830714","display_name":"FEBS Letters","issn_l":"0014-5793","issn":["0014-5793","1873-3468"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEBS Letters","raw_type":"journal-article"},{"id":"pmid:14706843","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14706843","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEBS letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320325035","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77"},{"id":"https://openalex.org/F4320333063","display_name":"Stanford Bio-X","ror":"https://ror.org/00f54p054"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1483463110","https://openalex.org/W1513720422","https://openalex.org/W1519865990","https://openalex.org/W1965594934","https://openalex.org/W1979481911","https://openalex.org/W1988938688","https://openalex.org/W2001018111","https://openalex.org/W2012563600","https://openalex.org/W2031189086","https://openalex.org/W2038069471","https://openalex.org/W2038352464","https://openalex.org/W2046721512","https://openalex.org/W2049330690","https://openalex.org/W2051741047","https://openalex.org/W2056817403","https://openalex.org/W2063134564","https://openalex.org/W2065304353","https://openalex.org/W2067714035","https://openalex.org/W2073302388","https://openalex.org/W2074117716","https://openalex.org/W2075890683","https://openalex.org/W2077798236","https://openalex.org/W2078481023","https://openalex.org/W2084047073","https://openalex.org/W2093868134","https://openalex.org/W2094489008","https://openalex.org/W2099722059","https://openalex.org/W2137683543","https://openalex.org/W2141979703","https://openalex.org/W2146142695","https://openalex.org/W2155733474","https://openalex.org/W2157163471","https://openalex.org/W2164047897","https://openalex.org/W2167869241","https://openalex.org/W2411711343","https://openalex.org/W2415772383","https://openalex.org/W3010029181","https://openalex.org/W4229738735"],"related_works":["https://openalex.org/W1531537539","https://openalex.org/W2341399252","https://openalex.org/W1979481911","https://openalex.org/W2136413219","https://openalex.org/W6998433719","https://openalex.org/W2041059150","https://openalex.org/W1623463470","https://openalex.org/W1602844888","https://openalex.org/W2116376573","https://openalex.org/W2395937405"],"abstract_inverted_index":{"Gene":[0],"expression":[1,35],"patterns":[2],"in":[3,46,59,105],"response":[4,34,95],"to":[5,109],"hydrostatic":[6,92],"pressure":[7,23],"were":[8,44,58,70],"determined":[9],"by":[10,22],"whole":[11],"genome":[12],"microarray":[13],"hybridization.":[14],"Functional":[15],"classification":[16],"of":[17,25,39,54,80,87,107],"the":[18,40,55,72,81,102],"274":[19],"genes":[20,43,69],"affected":[21],"treatment":[24],"200":[26],"MPa":[27],"for":[28],"30":[29],"min":[30],"revealed":[31,90],"a":[32,91,110],"stress":[33,47,94],"profile.":[36],"The":[37,85],"majority":[38],">2-fold":[41],"upregulated":[42,83],"involved":[45,104],"defense":[48],"and":[49,63,77,97],"carbohydrate":[50],"metabolism":[51],"while":[52],"most":[53],"repressed":[56],"ones":[57],"cell":[60],"cycle":[61],"progression":[62],"protein":[64],"synthesis":[65],"categories.":[66],"Furthermore,":[67],"uncharacterized":[68],"among":[71],"10":[73],"highest":[74],"expressed":[75],"sequences":[76],"represented":[78],"45%":[79],"total":[82],"genes.":[84],"results":[86],"this":[88],"study":[89],"pressure-specific":[93],"pattern":[96],"suggested":[98],"interesting":[99],"information":[100],"about":[101],"mechanisms":[103],"adaptation":[106],"cells":[108],"high-pressure":[111],"environment.":[112]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}