{"id":"https://openalex.org/W1997669659","doi":"https://doi.org/10.1016/j.jss.2005.11.439","title":"Effects of HBOC-201 resuscitation on nitric oxide physiology in vitro","display_name":"Effects of HBOC-201 resuscitation on nitric oxide physiology in vitro","publication_year":2006,"publication_date":"2006-01-27","ids":{"openalex":"https://openalex.org/W1997669659","doi":"https://doi.org/10.1016/j.jss.2005.11.439","mag":"1997669659"},"language":"en","primary_location":{"id":"doi:10.1016/j.jss.2005.11.439","doi":"https://doi.org/10.1016/j.jss.2005.11.439","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jss.2005.11.439","pdf_url":null,"source":{"id":"https://openalex.org/S45161156","display_name":"Journal of Surgical Research","issn_l":"0022-4804","issn":["0022-4804","1095-8673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020263309","display_name":"Colleen M. Fitzpatrick","orcid":"https://orcid.org/0000-0001-7460-4980","observed_orcids":["https://orcid.org/0000-0001-7460-4980"]},"institutions":[{"id":"https://openalex.org/I2799567722","display_name":"Wilford Hall Ambulatory Surgical Center","ror":"https://ror.org/025m0q735","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2799567722","https://openalex.org/I2802362820","https://openalex.org/I4210102105","https://openalex.org/I4210119345"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.M. Fitzpatrick","raw_affiliation_strings":["Wilford Hall Medical Center, San Antonio, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wilford Hall Medical Center, San Antonio, TX","institution_ids":["https://openalex.org/I2799567722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103503141","display_name":"Patricia Dixon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799567722","display_name":"Wilford Hall Ambulatory Surgical Center","ror":"https://ror.org/025m0q735","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2799567722","https://openalex.org/I2802362820","https://openalex.org/I4210102105","https://openalex.org/I4210119345"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P.S. Dixon","raw_affiliation_strings":["Wilford Hall Medical Center, San Antonio, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wilford Hall Medical Center, San Antonio, TX","institution_ids":["https://openalex.org/I2799567722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110913098","display_name":"Broadus Zane Atkins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799567722","display_name":"Wilford Hall Ambulatory Surgical Center","ror":"https://ror.org/025m0q735","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2799567722","https://openalex.org/I2802362820","https://openalex.org/I4210102105","https://openalex.org/I4210119345"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B.Z. Atkins","raw_affiliation_strings":["Wilford Hall Medical Center, San Antonio, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wilford Hall Medical Center, San Antonio, TX","institution_ids":["https://openalex.org/I2799567722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051618080","display_name":"Stephanie A. Savage","orcid":"https://orcid.org/0000-0001-6634-3098","observed_orcids":["https://orcid.org/0000-0001-6634-3098"]},"institutions":[{"id":"https://openalex.org/I2799567722","display_name":"Wilford Hall Ambulatory Surgical Center","ror":"https://ror.org/025m0q735","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2799567722","https://openalex.org/I2802362820","https://openalex.org/I4210102105","https://openalex.org/I4210119345"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S.A. Savage","raw_affiliation_strings":["Wilford Hall Medical Center, San Antonio, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wilford Hall Medical Center, San Antonio, TX","institution_ids":["https://openalex.org/I2799567722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035870137","display_name":"Jeffrey David Kerby","orcid":"https://orcid.org/0000-0001-7368-1124","observed_orcids":["https://orcid.org/0000-0001-7368-1124"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.D. Kerby","raw_affiliation_strings":["The University of Alabama at Birmingham, Birmingham, AL,","The Univ of Alabama at Birmingham, Birmingham, AL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Alabama at Birmingham, Birmingham, AL,","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"The Univ of Alabama at Birmingham, Birmingham, AL","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040420566","display_name":"Vikram S. Kashyap","orcid":"https://orcid.org/0000-0003-1780-979X","observed_orcids":["https://orcid.org/0000-0003-1780-979X"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V.S. Kashyap","raw_affiliation_strings":["The Cleveland Clinic Foundation, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Cleveland Clinic Foundation, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14401657,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"130","issue":"2","first_page":"312","last_page":"312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.04560000076889992,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hboc-201","display_name":"HBOC-201","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hemoglobin-based-oxygen-carriers","display_name":"hemoglobin-based oxygen carriers","score":0.8640000224113464},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.9330000281333923},{"id":"https://openalex.org/keywords/endothelial-nitric-oxide-synthase","display_name":"endothelial nitric oxide synthase","score":0.968999981880188},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.8500000238418579},{"id":"https://openalex.org/keywords/aortic-endothelium","display_name":"aortic endothelium","score":0.7239999771118164},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.6570000052452087},{"id":"https://openalex.org/keywords/cell-viability","display_name":"cell viability","score":0.6809999942779541},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8479999899864197},{"id":"https://openalex.org/keywords/vasoconstriction","display_name":"vasoconstriction","score":0.7429999709129333},{"id":"https://openalex.org/keywords/lactated-ringer-s-solution","display_name":"lactated Ringer's solution","score":0.8090000152587891},{"id":"https://openalex.org/keywords/l-arginine","display_name":"L-arginine","score":0.367000013589859}],"concepts":[{"id":"https://openalex.org/C2778326061","wikidata":"https://www.wikidata.org/wiki/Q1761022","display_name":"Enos","level":4,"score":0.7847549915313721},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.6812841892242432},{"id":"https://openalex.org/C2777622882","wikidata":"https://www.wikidata.org/wiki/Q417619","display_name":"Nitric oxide synthase","level":3,"score":0.4710927903652191},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.44515806436538696},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.43842190504074097},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.41906973719596863},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.3916776776313782},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3575795888900757},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35259202122688293},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.34634673595428467},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3349590003490448},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2655304968357086}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jss.2005.11.439","doi":"https://doi.org/10.1016/j.jss.2005.11.439","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jss.2005.11.439","pdf_url":null,"source":{"id":"https://openalex.org/S45161156","display_name":"Journal of Surgical Research","issn_l":"0022-4804","issn":["0022-4804","1095-8673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1982283356","https://openalex.org/W2586822926","https://openalex.org/W2135279998","https://openalex.org/W2913846631","https://openalex.org/W2132841791","https://openalex.org/W2015453414","https://openalex.org/W2089334038","https://openalex.org/W2914003330","https://openalex.org/W2007854210","https://openalex.org/W2045707675"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}