{"id":"https://openalex.org/W1997566637","doi":"https://doi.org/10.1292/jvms.13-0589","title":"Anesthetic Effect of a Combination of Medetomidine-Midazolam-Butorphanol in Cynomolgus Monkeys (Macaca fascicularis)","display_name":"Anesthetic Effect of a Combination of Medetomidine-Midazolam-Butorphanol in Cynomolgus Monkeys (Macaca fascicularis)","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W1997566637","doi":"https://doi.org/10.1292/jvms.13-0589","mag":"1997566637","pmid":"https://pubmed.ncbi.nlm.nih.gov/24584083","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4108780"},"language":"en","primary_location":{"id":"doi:10.1292/jvms.13-0589","doi":"https://doi.org/10.1292/jvms.13-0589","is_oa":true,"landing_page_url":"https://doi.org/10.1292/jvms.13-0589","pdf_url":"https://www.jstage.jst.go.jp/article/jvms/76/6/76_13-0589/_pdf","source":{"id":"https://openalex.org/S40103090","display_name":"Journal of Veterinary Medical Science","issn_l":"0916-7250","issn":["0916-7250","1347-7439"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313482","host_organization_name":"Japanese Society of Veterinary Science","host_organization_lineage":["https://openalex.org/P4310313482"],"host_organization_lineage_names":["Japanese Society of Veterinary Science"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Veterinary Medical Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jstage.jst.go.jp/article/jvms/76/6/76_13-0589/_pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111723956","display_name":"Takehiro Ochi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Takehiro OCHI","raw_affiliation_strings":["Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081307026","display_name":"Ippei Nishiura","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ippei NISHIURA","raw_affiliation_strings":["Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mitsuyoshi TATSUMI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mitsuyoshi TATSUMI","raw_affiliation_strings":["Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007047818","display_name":"Yoshimi Hirano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yoshimi HIRANO","raw_affiliation_strings":["Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066502180","display_name":"Kouichi Yahagi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kouichi YAHAGI","raw_affiliation_strings":["Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yasuhiro SAKURAI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yasuhiro SAKURAI","raw_affiliation_strings":["Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049597763","display_name":"Kanako MATSUYAMA-FUJIWARA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kanako MATSUYAMA-FUJIWARA","raw_affiliation_strings":["Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033806624","display_name":"Yuji Sudo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yuji SUDO","raw_affiliation_strings":["Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006272251","display_name":"Noriko Nishina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142395110","display_name":"Astellas Pharma (Japan)","ror":"https://ror.org/01cjash87","country_code":"JP","type":"company","lineage":["https://openalex.org/I142395110"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Noriko NISHINA","raw_affiliation_strings":["Drug Safety Research Labs, Astellas Pharma Inc., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan","Drug Safety Research Laboratories, Astellas Pharma Inc, 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Safety Research Labs, Astellas Pharma Inc., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan","institution_ids":["https://openalex.org/I142395110"]},{"raw_affiliation_string":"Drug Safety Research Laboratories, Astellas Pharma Inc, 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan","institution_ids":["https://openalex.org/I142395110"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113512477","display_name":"H. Koyama","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hironari KOYAMA","raw_affiliation_strings":["Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1\u20136 Kashima 2-chome, Yodogawa-ku, Osaka 532\u20138514, Japan","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111723956"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9619,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.84250032,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"76","issue":"6","first_page":"917","last_page":"921"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11905","display_name":"Veterinary Pharmacology and Anesthesia","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11905","display_name":"Veterinary Pharmacology and Anesthesia","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10838","display_name":"Animal Behavior and Welfare Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medetomidine","display_name":"medetomidine","score":0.9890000224113464},{"id":"https://openalex.org/keywords/midazolam","display_name":"midazolam","score":1.0},{"id":"https://openalex.org/keywords/butorphanol","display_name":"butorphanol","score":1.0},{"id":"https://openalex.org/keywords/combined-anesthesia","display_name":"combined anesthesia","score":0.7289999723434448},{"id":"https://openalex.org/keywords/cynomolgus-monkeys","display_name":"Macaca fascicularis","score":0.9570000171661377},{"id":"https://openalex.org/keywords/atipamezole","display_name":"atipamezole","score":0.9049999713897705},{"id":"https://openalex.org/keywords/alpha2-adrenoceptor-antagonists","display_name":"alpha2-adrenoceptor antagonists","score":0.8349999785423279},{"id":"https://openalex.org/keywords/anesthesia-duration","display_name":"anesthesia duration","score":0.6669999957084656},{"id":"https://openalex.org/keywords/hematological-parameters","display_name":"hematological parameters","score":0.7179999947547913},{"id":"https://openalex.org/keywords/serum-biochemical-parameters","display_name":"serum biochemical parameters","score":0.7559999823570251},{"id":"https://openalex.org/keywords/veterinary-anesthesia","display_name":"veterinary anesthesia","score":0.45899999141693115}],"concepts":[{"id":"https://openalex.org/C2776312488","wikidata":"https://www.wikidata.org/wiki/Q413894","display_name":"Atipamezole","level":5,"score":0.9756145477294922},{"id":"https://openalex.org/C2781020239","wikidata":"https://www.wikidata.org/wiki/Q1185089","display_name":"Butorphanol","level":2,"score":0.9450646638870239},{"id":"https://openalex.org/C2779520467","wikidata":"https://www.wikidata.org/wiki/Q427179","display_name":"Medetomidine","level":4,"score":0.9124389886856079},{"id":"https://openalex.org/C2778000748","wikidata":"https://www.wikidata.org/wiki/Q423071","display_name":"Midazolam","level":3,"score":0.8631251454353333},{"id":"https://openalex.org/C2778162923","wikidata":"https://www.wikidata.org/wiki/Q4990531","display_name":"Anesthetic","level":2,"score":0.78055340051651},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6302171945571899},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.5272437930107117},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5188049674034119},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4696340560913086},{"id":"https://openalex.org/C2992926266","wikidata":"https://www.wikidata.org/wiki/Q609370","display_name":"Adult male","level":2,"score":0.42098894715309143},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.326541930437088},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1601411998271942},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.14952191710472107},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14391037821769714},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.10453006625175476},{"id":"https://openalex.org/C2776814716","wikidata":"https://www.wikidata.org/wiki/Q574801","display_name":"Sedation","level":2,"score":0.08979469537734985},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.07223543524742126}],"mesh":[{"descriptor_ui":"D000758","descriptor_name":"Anesthesia","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D000777","descriptor_name":"Anesthetics","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002077","descriptor_name":"Butorphanol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D002077","descriptor_name":"Butorphanol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007273","descriptor_name":"Injections, Intramuscular","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D008252","descriptor_name":"Macaca fascicularis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008874","descriptor_name":"Midazolam","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D008874","descriptor_name":"Midazolam","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019162","descriptor_name":"Anesthetics, Combined","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D019162","descriptor_name":"Anesthetics, Combined","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D020926","descriptor_name":"Medetomidine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D020926","descriptor_name":"Medetomidine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1292/jvms.13-0589","doi":"https://doi.org/10.1292/jvms.13-0589","is_oa":true,"landing_page_url":"https://doi.org/10.1292/jvms.13-0589","pdf_url":"https://www.jstage.jst.go.jp/article/jvms/76/6/76_13-0589/_pdf","source":{"id":"https://openalex.org/S40103090","display_name":"Journal of Veterinary Medical Science","issn_l":"0916-7250","issn":["0916-7250","1347-7439"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313482","host_organization_name":"Japanese Society of Veterinary Science","host_organization_lineage":["https://openalex.org/P4310313482"],"host_organization_lineage_names":["Japanese Society of Veterinary Science"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Veterinary Medical Science","raw_type":"journal-article"},{"id":"pmid:24584083","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24584083","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of veterinary medical science","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4108780","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4108780/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Vet Med Sci","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.804.8041","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.804.8041","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/3d/1f/jvms-76-917.PMC4108780.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1292/jvms.13-0589","doi":"https://doi.org/10.1292/jvms.13-0589","is_oa":true,"landing_page_url":"https://doi.org/10.1292/jvms.13-0589","pdf_url":"https://www.jstage.jst.go.jp/article/jvms/76/6/76_13-0589/_pdf","source":{"id":"https://openalex.org/S40103090","display_name":"Journal of Veterinary Medical Science","issn_l":"0916-7250","issn":["0916-7250","1347-7439"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313482","host_organization_name":"Japanese Society of Veterinary Science","host_organization_lineage":["https://openalex.org/P4310313482"],"host_organization_lineage_names":["Japanese Society of Veterinary Science"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Veterinary Medical Science","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1997566637.pdf","grobid_xml":"https://content.openalex.org/works/W1997566637.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W14414806","https://openalex.org/W46807049","https://openalex.org/W130309539","https://openalex.org/W1547007062","https://openalex.org/W1883003388","https://openalex.org/W1958308969","https://openalex.org/W1966684950","https://openalex.org/W1971042825","https://openalex.org/W1982277489","https://openalex.org/W1984512724","https://openalex.org/W1997746998","https://openalex.org/W2000253499","https://openalex.org/W2018393962","https://openalex.org/W2060940547","https://openalex.org/W2079556793","https://openalex.org/W2108847838","https://openalex.org/W2116948571","https://openalex.org/W2276252199","https://openalex.org/W2401119697","https://openalex.org/W4295192786","https://openalex.org/W4360771646"],"related_works":["https://openalex.org/W2395228328","https://openalex.org/W2947308046","https://openalex.org/W2060940547","https://openalex.org/W2079556793","https://openalex.org/W1997746998","https://openalex.org/W7097164421","https://openalex.org/W2416408784","https://openalex.org/W1883003388","https://openalex.org/W2000253499","https://openalex.org/W7221560708"],"abstract_inverted_index":{"The":[0,18,54,67,96],"anesthetic":[1,97,142],"effect":[2,98,143],"of":[3,6,69,99,115],"a":[4],"combination":[5,20,55,101,128,139],"medetomidine,":[7],"midazolam":[8],"and":[9,44,59,89,144],"butorphanol":[10],"(Me-Mi-Bu)":[11],"was":[12,21,62,75,102],"evaluated":[13],"in":[14,112,123],"healthy":[15],"cynomolgus":[16,124,151],"monkeys.":[17,152],"Me-Mi-Bu":[19,138],"intramuscularly":[22],"administered":[23,74,126],"as":[24],"follows:":[25,76],"Dose":[26,35,45,77,83,90],"1,":[27,78],"Me":[28,37,47],"0.015":[29],"mg/kg-Mi":[30,39,49],"0.1":[31],"mg/kg-Bu":[32,41,51],"0.15":[33,40],"mg/kg;":[34,43],"2,":[36,84],"0.02":[38],"0.2":[42],"3,":[46,91],"0.04":[48],"0.3":[50],"0.4":[52],"mg/kg.":[53],"rapidly":[56],"induced":[57],"immobilization,":[58],"lateral":[60],"recumbency":[61],"reached":[63],"within":[64],"15":[65],"min.":[66,95],"duration":[68],"anesthesia":[70],"for":[71,148],"each":[72],"dose":[73],"47":[79],"\u00b1":[80,86,93],"27":[81],"min;":[82,88],"113":[85],"31":[87],"190":[92],"24":[94],"the":[100,105,113,127,137],"abolished":[103],"by":[104],"\u03b12-adrenoceptor":[106],"antagonist":[107],"atipamezole.":[108,130],"No":[109],"marked":[110],"changes":[111],"levels":[114],"hematologic":[116],"or":[117],"serum":[118],"biochemical":[119],"parameters":[120],"were":[121],"noted":[122],"monkeys":[125],"plus":[129],"Taken":[131],"together,":[132],"these":[133],"results":[134],"suggest":[135],"that":[136],"exhibits":[140],"reversible":[141],"may":[145],"be":[146],"useful":[147],"studies":[149],"involving":[150]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}